WO2014049924A1 - Cartridge holder, cartridge unit, and drug injection device to which cartridge unit is mounted - Google Patents

Cartridge holder, cartridge unit, and drug injection device to which cartridge unit is mounted Download PDF

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Publication number
WO2014049924A1
WO2014049924A1 PCT/JP2013/004453 JP2013004453W WO2014049924A1 WO 2014049924 A1 WO2014049924 A1 WO 2014049924A1 JP 2013004453 W JP2013004453 W JP 2013004453W WO 2014049924 A1 WO2014049924 A1 WO 2014049924A1
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WO
WIPO (PCT)
Prior art keywords
cartridge
holder
opening
stopper
contact
Prior art date
Application number
PCT/JP2013/004453
Other languages
French (fr)
Japanese (ja)
Inventor
飯尾　敏明
池川　泰造
村上　健二
矢野　賢一
幸広 高畑
Original Assignee
パナソニックヘルスケア株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by パナソニックヘルスケア株式会社 filed Critical パナソニックヘルスケア株式会社
Publication of WO2014049924A1 publication Critical patent/WO2014049924A1/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
    • A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
    • A61M5/14546—Front-loading type injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically

Definitions

  • the present invention relates to a cartridge holder, a cartridge unit, and a medicine injection device to which the cartridge unit is attached.
  • the following configuration is disclosed as a conventional drug injection device of this type.
  • a configuration of a drug injection device including a holder into which a syringe preparation pre-filled with a drug is inserted, a dispensing device fixed to the end of the holder, and a chemical liquid metering injector connected to the dispensing device. It is disclosed (for example, see Patent Document 1).
  • the drug injection device having such a configuration is provided to a hospital or a patient in a state in which a syringe preparation is inserted into a holder and a dispensing device and a drug metering injector are connected to the holder and assembled.
  • a user such as a doctor or a patient drives the piston to inject the preparation in the syringe preparation into a human body or the like from the injection needle attached to the distal end side of the syringe preparation.
  • the drug injection device of Patent Document 1 is generally disposable, but a drug injection device using a replaceable cartridge preparation is also used. In such a drug injection device, after mounting the cartridge, a piston provided in the drug injection device is inserted into the cartridge preparation, and drug injection is performed. When the contents of the cartridge preparation disappear, the user can inject the medicine by mounting a new cartridge preparation.
  • an object of the present invention is to provide a cartridge holder, a cartridge unit, and a medicine injection device capable of reducing damage to the cartridge preparation due to dropping or the like in consideration of the problems of the conventional cartridge preparation.
  • the cartridge holder of the present invention is a cartridge holder that holds a cartridge containing a medicine and is attached to the medicine injection device, and includes a holder body and a stopper.
  • the holder body has a cylindrical shape having a first opening into which the cartridge is inserted and an engaged portion provided on the side surface.
  • the stopper is formed with a second opening into which a drug injection piston provided in the drug injection device is inserted, and protrudes from the periphery of the second opening to be attached to the holder body.
  • the perspective view which shows the chemical injection device in embodiment concerning this invention 1 is an exploded perspective view of the drug injection device of FIG. Sectional drawing for demonstrating the operation state of the chemical
  • worn 4 is an exploded perspective view of the cartridge unit of FIG. 4 is an exploded perspective view of the cartridge unit of FIG. Sectional view of the cartridge unit of FIG.
  • the perspective view of the stopper which comprises the cartridge unit of FIG. Sectional view of the stopper of FIG. Plan view of the stopper of FIG. Sectional drawing which shows the rear end vicinity of the cartridge unit of FIG. 4A is a sectional view showing the vicinity of the positioning portion of the cartridge unit of FIG. 4, and FIG.
  • FIG. 4B is a plan view showing the vicinity of the cartridge holding portion of the cartridge unit of FIG. Sectional drawing which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention Sectional drawing which shows the rear end vicinity of the cartridge unit in the modification of embodiment concerning this invention
  • the top view which shows the modification of the stopper of the cartridge unit in the modification of embodiment concerning this invention The top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention
  • the top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention The top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention
  • the top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention (A) Top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention, (b) DD 'sectional drawing of Fig.19 (a) (A) Top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention, (b) Sectional drawing between EE 'of Fig.20
  • FIG. 1 is a perspective view showing the appearance of the drug injection device of the present embodiment.
  • FIG. 2 is an exploded perspective view of the drug injection device according to the present embodiment.
  • the front end side or the front end side indicates the direction in which the medicine is injected (opening 9 side), and the rear end side indicates the opposite direction (the power button 5 side).
  • the drug injection device has a main body case 1. 1 and 2, a display unit 2 is provided on the front side of the main body case 1, and an air vent button 3 and a completion button 4 are provided on the side of the display unit 2. Further, a power button 5 is provided on the right side of the display unit 2 in FIG. Further, a medicine injection button 6 is provided on the left side of the display unit 2 and on the front end side of the main body case 1.
  • a front end cap 7 is detachably attached to the front end side of the main body case 1.
  • the tip cap 7 is provided with a confirmation window 8 on the front side in FIG.
  • An opening 9 is provided on the front end side of the tip cap 7 as shown in FIG.
  • a cartridge unit 10 including a cartridge preparation 21 and a cartridge holder 30 is attached to a portion in the tip cap 7 that can be seen from the confirmation window 8.
  • a needle cap 11 that protects the injection needle 12 attached to the front end side of the cartridge unit 10 is shown.
  • the tip cap 7 attached to the main body case 1 is removed from the main body case 1 as shown in FIG. In this state, the cartridge unit 10 is mounted on the mounting portion 13 (see FIG. 2) of the main body case 1 from the rear end side, and the needle cap 11 is mounted on the front end side of the cartridge unit 10. Thereafter, the tip cap 7 is attached to the main body case 1.
  • FIG. 3 is a cross-sectional view for illustrating an operating state of the pharmaceutical injection device according to the present embodiment.
  • the drug injection device includes a mounting portion 13, a piston 14, a motor 15, and a piston fixing portion 29.
  • the mounting portion 13 is an inner case provided in the main body case 1.
  • the cartridge unit 10 is mounted in the mounting portion 13.
  • the piston 14 is inserted into the cartridge preparation 21 of the cartridge unit 10, whereby the preparation in the cartridge preparation 21 is injected into the human body or the like via the injection needle 12.
  • the piston fixing part 29 fixes the position of the piston 14, and the position is fixed with respect to the cartridge unit 10.
  • the motor 15 drives the piston 14 to push the piston 14 toward the injection needle 12 side.
  • FIG. 4 is a perspective view of the cartridge unit 10 of the present embodiment.
  • FIG. 5 is an exploded perspective view of the cartridge unit 10 of the present embodiment.
  • FIG. 6 is an exploded perspective view of the cartridge unit 10 viewed from a direction different from that in FIG.
  • FIG. 7 is a cross-sectional view of the cartridge unit 10 of the present embodiment, and is a cross-sectional view taken along the line AA ′ of FIG. Further, AA ′ is also shown in FIG. 10 described later.
  • the cartridge unit 10 of the present embodiment includes a cartridge preparation 21 and a cartridge holder 30.
  • the cartridge holder 30 includes a holder main body 40 and a stopper 22. (Holder body 40)
  • the holder main body 40 has a cylindrical shape, and includes a cylindrical portion 41, a connection portion 42, a positioning portion 18, a holder main body front end side opening 16, and a holder main body rear end side. An opening 17 and an engagement opening 25 are provided.
  • the connecting portion 42 is provided on the front end side of the cylindrical portion 41, has a smaller diameter than the cylindrical portion 41, and has a screw portion formed on the outer peripheral side surface thereof.
  • the screw portion and the screw portion formed on the injection needle 12 (see FIG. 3) arranged inside the needle cap 11 (see FIG. 2) are screwed together, and the needle cap 11 is connected to the holder body 40.
  • the positioning portion 18 is provided between the cylindrical portion 41 and the connection portion 42, and is formed in a tapered shape whose diameter decreases from the cylindrical portion 41 toward the connection portion 42.
  • the positioning portion 18 abuts on a distal end side abutting portion 19 of the cartridge preparation 21 described later in a state where the cartridge preparation 21 is stored in the holder main body 40.
  • the holder main body front end side opening 16 is provided on the front end side of the holder main body 40 (also referred to as an injection needle mounting side on which the injection needle 12 is mounted), and is provided inside the connection portion 42. Is done.
  • the holder main body rear end side opening 17 is provided on the rear end side (also referred to as piston insertion side) opposite to the holder main body front end side opening 16, and the stopper 22 is inserted.
  • the engagement openings 25 are holes formed through the side surface of the cylindrical portion 41, and are formed at four locations along the circumferential direction near the holder body rear end side opening 17. An engagement claw 24 of a stopper 22 described later engages with the engagement opening 25.
  • the cartridge preparation 21 is cylindrical and is accommodated in the holder body 40.
  • the cartridge preparation 21 is pre-filled with a medicine for injection such as insulin.
  • the cartridge preparation 21 has a cylindrical portion 51, a connection portion 52, a distal end side contact portion 19, and a cartridge opening 20.
  • the cylindrical part 51 is filled with a medicine.
  • the connecting portion 52 is provided on the front end side of the cylindrical portion 51, has a smaller diameter than the cylindrical portion 51, and the injection needle 12 is connected through the inside thereof.
  • the connection part 52 is provided with a rubber-like cap part 152, and the cartridge preparation 21 is sealed.
  • the needle cap 11 by connecting the needle cap 11 to the holder main body 40 in a state in which the cartridge preparation 21 is stored in the cartridge holder 30, the injection needle 12 disposed in the needle cap 11 is inserted through the opening 16 on the distal end side of the holder main body. It is attached to the connection part 52 of the cartridge preparation 21.
  • the front end side contact portion 19 is provided between the cylindrical portion 51 and the connection portion 52, and is formed in a tapered shape whose diameter decreases from the cylindrical portion 51 toward the connection portion 52.
  • the distal end side contact portion 19 comes into contact with the tapered positioning portion 18.
  • the front end side contact portion 19 slides with respect to the positioning portion 18, and the cartridge preparation 21 is positioned at a substantially center in the radial direction of the holder main body 40.
  • positioning of the cartridge preparation 21 with respect to the cartridge holder 30 is performed.
  • the cartridge opening 20 is provided at the rear end of the cartridge preparation 21 and the piston 14 is inserted therein.
  • the cartridge opening 20 is sealed with a gasket 153.
  • the gasket 153 is pushed, and the medicine in the cylindrical part 51 is injected from the injection needle 12 connected to the connection part 52.
  • FIG. 8 is a perspective view of the stopper 22 of the present embodiment.
  • FIG. 9 is a side sectional view of the stopper 22 of the present embodiment.
  • FIG. 10 is a plan view of the stopper 22 of the present embodiment. 9 is a cross-sectional view taken along CC ′ in FIG. In FIG. 10, the outer peripheral edge 21T at the rear end of the cartridge preparation 21 is indicated by a two-dot chain line.
  • the stopper 22 is made of synthetic resin and is softer than the piston 14. As shown in FIGS. 8 to 10, the stopper 22 has an engaging claw 24 and a cartridge holding part 50.
  • the cartridge holding unit 50 holds the cartridge preparation 21 in the cartridge holder 30.
  • the cartridge holding portion 50 is provided with a lid portion 53 and a contact claw 26.
  • the lid 53 has a disk shape, and a piston insertion opening 23 is provided at the center thereof.
  • the piston insertion opening 23 is disposed at a position corresponding to the cartridge opening 20 of the cartridge preparation 21, and the piston 14 is inserted at the time of drug injection.
  • the lid 53 is arranged so that the piston insertion opening 23 faces the cartridge opening 20 in a state in which the stopper 22 is mounted on the holder main body 40.
  • the peripheral edge 23e of the piston insertion opening 23 is formed in an R shape.
  • the contact support portion 260 is a plate-like member that is curved along the outer peripheral edge of the lid portion 53.
  • the protrusion 27 protrudes toward the central axis 22a (see FIG.
  • FIG. 11 is a cross-sectional view showing a peripheral portion of the stopper 22 in a state where the stopper 22 is mounted on the holder main body 40 in which the cartridge preparation 21 is inserted.
  • the cartridge preparation 21 is disposed so as to be sandwiched between the protrusions 27 of the contact claw 26, and moved to the holder body rear end side opening 17 by the lid 53. The cartridge preparation 21 is held in the cartridge holder 30.
  • engagement claw 24 Four engagement claws 24 are provided on the outer peripheral edge of the lid 53 with a predetermined interval. In other words, the four engaging claws 24 are arranged at intervals of 90 degrees around the central axis 22a in plan view. Each engagement claw 24 is provided between the contact claws 26. More specifically, as shown in FIGS. 8 and 9, the engagement claw 24 includes an engagement support portion 240 formed in a substantially vertical direction from the outer peripheral edge of the lid portion 53 to the lid portion 53, and an engagement support portion. The claw portion 241 is provided outside the front end portion of the 240 and supported by the engagement support portion 240.
  • the engagement support portion 240 is a plate-like member that is curved along the outer peripheral edge of the lid portion 53, and is formed longer than the contact support portion 260.
  • the claw portion 241 has an inclined surface 241 a formed on the outer peripheral side so that the length of the claw portion 241 protrudes outward from the end of the engagement support portion 240 toward the lid portion 53.
  • An engagement surface 241b is formed between the lower end of the claw portion 241, that is, between the lower end of the inclined surface 241 a and the engagement support portion 240.
  • the engagement surface 241b contacts the edge on the rear end side of the engagement opening 25, and the claw 241 engages with the engagement opening 25 (see FIG. 4). Further, as shown in FIG.
  • the engagement surface 241 b is formed with an acute angle ⁇ with the outer surface of the engagement support portion 240.
  • the engaging claw 24 can be smoothly inserted when inserted into the holder main body 40.
  • the stopper 22 has the piston insertion opening 23, and the inner periphery of the holder main body rear end side opening 17 of the holder main body 40 is provided on the outer peripheral edge of the lid 53 where the piston insertion opening 23 is formed.
  • An engaging claw 24 to be inserted into the is provided.
  • An engagement opening 25 to which the engagement claw 24 engages is provided on the side surface portion of the holder main body 40 corresponding to the outer peripheral direction of the engagement claw 24.
  • the cartridge preparation 21 is mounted on the storage / portable / pharmaceutical injection device while being mounted in the cartridge holder 30. Further, the cartridge preparation 21 has a distal end side contact portion 19 that is in contact with a positioning portion 18 provided inside the holder body distal end side opening 16 on the distal end side, and a piston end on the rear end side. 14 is provided with a cartridge opening 20 into which 14 is inserted.
  • a stopper 22 is mounted inside the holder body rear end opening 17.
  • the stopper 22 has a piston insertion opening 23 at a portion corresponding to the cartridge opening 20 of the cartridge preparation 21.
  • An engagement claw 24 to be inserted into the holder main body rear end side opening 17 of the holder main body 40 is provided on the outer peripheral edge of the piston insertion opening 23.
  • an engagement opening 25 to which the engagement claw 24 is engaged is provided in the portion of the holder main body 40 corresponding to the outer peripheral direction of the engagement claw 24, an engagement opening 25 to which the engagement claw 24 is engaged is provided.
  • the cartridge preparation 21 is always mounted in the cartridge holder 30. As a result, the cartridge preparation 21 was accidentally dropped during storage, carrying, or mounting on the drug injection device. Even so, damage to the cartridge preparation 21 can be prevented.
  • the cartridge preparation 21 is inserted into the holder body 40.
  • the cartridge preparation 21 is inserted into the holder main body 40 from the holder main body rear end side opening 17, the tapered front end side contact portion 19 and the tapered positioning portion 18 come into contact. From this state, the tip-side contact portion 19 and the positioning portion 18 slide together, and the cartridge preparation 21 is positioned approximately at the center in the radial direction in the holder main body 40. In other words, the central axis of the cartridge preparation 21 and the central axis of the holder body 40 are substantially overlapped.
  • the stopper 22 is inserted into the holder main body 40 so as to close the holder main body rear end side opening 17.
  • the inclined surface 241a of the engaging claw 24 abuts on the edge 17a (see FIG. 5) of the holder main body rear end side opening 17.
  • the engagement support portion 240 bends inward (see arrow B in FIG. 11), so that the claw portion 241 enters the inside of the holder main body 40 along the edge 17a.
  • the front end side of the cartridge preparation 21 is located on the holder front end side in the positioning portion 18 by the stepped portion, and at least a part of the outer peripheral surface of the front end side of the cartridge preparation 21 in the holder main body 40. It has a structure held via a gap between the peripheral surface.
  • FIG. 12A is a cross-sectional view showing the vicinity of the positioning portion 18 and the distal end side contact portion 19.
  • the tapered positioning portion 18 is formed around the circumference of the holder body distal end side opening portion 16 over the entire circumference. Further, the tapered tip side contact portion 19 is also formed around the connection portion 52 over the entire circumference.
  • the cartridge preparation 21 is held in the cartridge holder 30 by the contact of the positioning portion 18 with the distal end side contact portion 19, but at least a part between the positioning portion 18 and the distal end side contact portion 19 is As shown in the enlarged view of the P portion, a gap S1 is provided.
  • the minute gap S1 disappears when the drug is injected, and the piston 14 presses the gasket 153, and the cartridge preparation 21 is accurately positioned in the longitudinal direction.
  • FIG. 12B is a plan view showing the rear end portion of the cartridge preparation 21.
  • the cartridge preparation 21 is held by the cartridge holder 30 by the contact of the protrusion 27 of the contact claw 26 with the outer peripheral surface of the cartridge preparation 21, but the outer peripheral surface 21 a of the cartridge preparation 21 and the four protrusions 27
  • a gap S2 is provided between at least one protrusion 27 as shown in the enlarged view of the Q portion.
  • the cartridge preparation 21 is held in the cartridge holder 30 through the slight gap on both the front end side and the rear end side, the impact applied to the cartridge holder 30 due to dropping or the like is directly applied. In this respect, the strength against impact is strong.
  • the lid portion 53 of the stopper 22 enters inside the edge 17 a that is the rear end of the holder body 40.
  • the edge 17a which is the rear end of the holder body 40, comes into contact with the ground, and damage due to dropping or the like can be reduced.
  • the engagement opening 25 is formed larger in the front-rear direction than the claw 241, the claw 241 can move in the front-rear direction in the engagement opening 25.
  • the cartridge preparation 21 can move slightly in the longitudinal direction together with the stopper 22 and can absorb the impact of the drop. It becomes possible.
  • the diameter R1 of the piston insertion opening 23 of the stopper 22 is equal to or smaller than the diameter R2 of the cartridge opening 20 of the cartridge preparation 21.
  • the stopper 22 is formed of synthetic resin, and the stopper 22 is formed to be softer than the piston 14. Thereby, when the piston 14 passes through the piston insertion opening 23 of the stopper 22, it is possible to prevent the piston 14 from being worn even if it comes into contact.
  • four (plural) engaging claws 24 are 90 degrees on the outer peripheral edge of the piston insertion opening 23 of the stopper 22, as shown in FIGS. They are provided at predetermined intervals. As a result, the stopper 22 can be firmly and securely mounted on the inner periphery of the holder body rear end opening 17 of the holder body 40.
  • a contact claw 26 is provided between the engaging claws 24, and a protrusion 27 protruding toward the outer peripheral surface of the cartridge preparation 21 is provided on the inner peripheral portion of the contact claw 26. Yes. For this reason, the support of the rear end side of the cartridge preparation 21 by the stopper 22 can be firmly and well balanced.
  • the cartridge preparation 21 is inserted into the holder main body 40, and then the stopper 22 is inserted from the holder main body rear end side opening 17 of the holder main body 40, and the engaging claw 24 is connected to the holder main body 40.
  • the label 28 shown in FIG. 5 covers the four engagement openings 25 provided at equal intervals on the outer periphery of the holder body 40 in the state engaged with the 40 engagement openings 25, that is, in the state shown in FIG. Is pasted.
  • the label 28 describes the type and expiration date of the cartridge preparation 21.
  • the label 28 can be engaged without being damaged.
  • the engaging claw 24 cannot be pushed inward from the opening 25 and removed.
  • the cartridge holder 30 of the present embodiment is a cartridge holder 30 that holds a cartridge preparation 21 (an example of a cartridge) containing a drug and is attached to a drug injection device. And a stopper 22.
  • the holder main body 40 has a cylindrical shape, and the holder main body rear end side opening 17 (an example of the first opening) into which the cartridge preparation 21 is inserted, and the engagement opening 25 provided on the side surface (engaged) Part).
  • the stopper 22 includes a piston insertion opening 23 (an example of a second opening) into which a drug injection piston 14 provided in the drug injection device is inserted, and a piston insertion opening 23 ( An engaging claw 24 that projects from the periphery of the second opening (an example of the second opening) and engages with the engaging opening 25 (an example of the engaged part), and holds the cartridge preparation 21 in the holder body 40.
  • the holder body 40 is attached to the holder body rear end side opening 17 (an example of the first opening).
  • the cartridge preparation 21 can be stored, carried, and attached to the medicine injection device as a unit with the cartridge preparation 21 and the cartridge holder 30 in a state of being mounted in the cartridge holder 30. For this reason, even if it is accidentally dropped at the time of storage, carrying, or mounting on a medicine injection device, damage to the cartridge preparation 21 can be prevented.
  • the drug injection device of the above embodiment is a device for automatically injecting a drug and is often used by a patient.
  • a cartridge preparation can be handled together with a holder for a patient who is not used to handling a drug, It becomes possible to operate safely and easily.
  • the cartridge preparation 21 can be easily held in the cartridge holder 30 simply by engaging the engagement claw 24 with the engagement opening 25. Further, for example, by pushing the engaging claw 24 inward, the engaging claw 24 can be separated from the engaging opening 25, and the cartridge preparation 21 can be taken out from the cartridge holder 30.
  • the cartridge holder 30 can be reused, so that costs can be reduced and resources can be reused. Further, when the stopper 22 is attached to the rear end portion of the cartridge preparation 21, the engaging claw 24 serves as a guide and is easy to attach.
  • the holder main body 40 includes a connection portion 42 (an example of a holder-side connection portion) and the positioning portion 18.
  • the connection part 42 is provided on the opposite side of the holder body rear end side opening part 17 (an example of the first opening part), and the injection needle 12 is connected thereto.
  • the positioning portion 18 is provided around the connection portion 42, and is formed in a tapered shape so that the diameter increases from the connection portion 42 toward the holder body rear end side opening portion 17.
  • the positioning portion 18 is formed around a connection portion 52 (an example of a cartridge-side connection portion) to which the injection needle 12 of the cartridge preparation 21 is connected, and has a distal end side contact portion 19 (having a tapered shape corresponding to the positioning portion 18).
  • the cartridge preparation 21 is positioned with respect to the cartridge holder 30 by abutting on an example of the outer peripheral surface.
  • the tip end side abutting portion 19 can slide automatically on the positioning portion 18 simply by inserting the cartridge preparation 21 into the cartridge holder 30, so that the inside of the cartridge holder 30 can be simply and easily saved. Positioning of the cartridge preparation 21 can be performed.
  • the positioning portion 18 also serves as a first holding portion that holds the cartridge, and the first holding portion is at least partially in the cartridge preparation 21 as shown in FIG.
  • a clearance S1 is provided between the tip end side contact portion 19 (an example of the outer peripheral surface) having a tapered shape.
  • the cartridge preparation 21 can be held in a state where the gap S1 is formed, the impact applied to the cartridge holder 30 by dropping or the like is not directly applied to the cartridge preparation 21, and the strength against impact is strong. It becomes.
  • the minute gap S1 disappears when the drug is injected, and the piston 14 presses the gasket 153, and the cartridge preparation 21 is accurately positioned in the longitudinal direction.
  • the stopper 22 further has a cartridge holding part 50 (an example of a second holding part) that holds the cartridge preparation 21.
  • the cartridge holding part 50 includes a lid part 53 and a plurality of contact claws 26 (an example of a contact part).
  • the lid 53 is provided with a piston insertion opening 23 (an example of a second opening) and is disposed so as to close the holder main body rear end side opening 17 (an example of a first opening).
  • the plurality of contact claws 26 are attached to the holder main body 40 from the periphery of the piston insertion opening 23 (an example of the second opening) of the lid portion 53 from the holder main body rear end side opening 17 (first opening). ) To project toward the side.
  • the cartridge preparation 21 is held so as to be sandwiched between the plurality of contact claws 26.
  • the cartridge preparation 21 can be held by a plurality of contact claws. Further, the cartridge preparation 21 can be held by the lid portion 53 coming into contact with the rear end of the cartridge preparation 21. For this reason, the cartridge preparation 21 can be held only by inserting the stopper 22 into the holder body 40. In addition, when the stopper 22 is attached to the rear end portion of the cartridge preparation 21, the plurality of contact claws 26 serve as guides and are easy to attach.
  • a gap is formed at least partially between the plurality of contact claws 26 and the cartridge preparation 21.
  • the diameter R1 of the piston insertion opening 23 (an example of the second opening) of the stopper 22 is the piston insertion into which the piston 14 of the cartridge preparation 21 is inserted. It is below the diameter R2 of the opening part 23 (an example of an insertion part).
  • the stopper 22 has an R shape at the peripheral edge 23e of the piston insertion opening 23 (an example of the second opening). Thereby, the piston 14 can pass smoothly through the piston insertion opening 23 of the stopper 22.
  • the stopper 22 is made of synthetic resin and is softer than the piston 14. Thereby, when the piston 14 passes through the piston insertion opening 23 of the stopper 22, it is possible to prevent the piston 14 from being worn even if it comes into contact.
  • a plurality of engagement claws 24 are provided along the outer periphery of the lid portion 53 with a predetermined interval.
  • the stopper 22 can be firmly and securely mounted on the inner periphery of the holder body rear end side opening 17 of the holder body 40.
  • a plurality of engagement claws 24 are provided along the outer periphery of the lid portion 53 with a predetermined interval.
  • the contact claw 26 (an example of a contact portion) is disposed between the engagement claws 24.
  • the contact claw 26 (an example of a contact portion) has a protrusion 27 provided toward the outer peripheral surface side of the cartridge preparation 21.
  • the cartridge unit 10 of the present embodiment includes a cartridge preparation 21 and a cartridge holder 30 in which the cartridge preparation 21 is stored.
  • the cartridge preparation 21 can be attached to the storage / portable / pharmaceutical injection device in a state of being attached in the cartridge holder 30. For this reason, even if it is accidentally dropped at the time of storage, carrying, or mounting on a medicine injection device, damage to the cartridge preparation 21 can be prevented.
  • the cartridge unit 10 includes a cartridge preparation 21, a cartridge holder 30 in which the cartridge preparation 21 is stored, and a label 28.
  • the engagement opening 25 is a hole formed in the side surface of the holder main body 40.
  • the label 28 is affixed to the cartridge holder 30 so as to close the engagement opening 25. Thereby, it becomes impossible to push the engagement claw 24 inwardly from the engagement opening 25 without damaging the label 28. As a result, it is possible to prevent the cartridge preparation 21 from being taken out of the cartridge holder 30 and then inserting another cartridge preparation 21.
  • the drug injection device includes a mounting portion 13 and a piston 14.
  • the mounting unit 13 is mounted with the cartridge unit 10.
  • the piston 14 passes from the piston insertion opening 23 (an example of the second opening) of the cartridge holder 30 of the cartridge unit 10 attached to the attachment part 13 via the cartridge opening 20 (an example of the insertion part) of the cartridge preparation 21. Is inserted into the cartridge preparation 21.
  • the cartridge preparation 21 can be attached to the medicine injecting device in a state where it is attached in the cartridge holder 30, and the medicine can be injected.
  • the peripheral edge 23e of the piston insertion opening 23 of the stopper 22 has an R shape on the insertion direction side of the piston 14, but is limited to such a shape. is not.
  • the edge 231e of the piston insertion opening 231 shown in FIG. 13 is formed in a tapered shape so that the diameter increases toward the rear end (piston 14 side).
  • the diameter R1 of the piston insertion opening 23 of the stopper 22 is equal to or smaller than the diameter R2 of the cartridge opening 20 of the cartridge preparation 21.
  • the diameter 14 may be smaller than the cartridge opening 20, and the diameter R 1 of the piston insertion opening 23 may be larger than the diameter R 2 of the cartridge opening 20.
  • R1 and R2 are set so that the edge of the piston insertion opening 23 does not overlap the cartridge opening 20. Further, the rear end surface 21 s of the cartridge preparation 21 overlaps the lid portion 53. The overlap portion is indicated by W.
  • L1 is set to a length in the range of 7 mm to 15 mm in consideration of assemblability.
  • the thickness of the engaging claw 24 is D1
  • D1 is set to a length in the range of 0.5 mm to 1 mm in consideration of assembling property and strength.
  • the dimension of the piston insertion opening 23 of the stopper 22 is preferably set to a dimension having a radius larger than the cartridge opening 20 by D2. This D2 is preferably set within a range of 0.2 mm to 0.5 mm.
  • the width of the engaging claw 24 is D3, it is preferable to set D3 in a range of 3 mm to 5 mm in consideration of assembling property and strength.
  • the four engaging claws 24 are provided along the outer periphery of the lid portion 53, and the abutting claws 26 are respectively provided between the engaging claws 24. . That is, the four engaging claws 24 are provided at equal intervals and the four contact claws 26 are provided at equal intervals.
  • the configuration is not limited to this.
  • a stopper 220 provided with two engagement claws 24 may be used.
  • the two engaging claws 24 are arranged to face each other.
  • a contact claw 66 is provided between each of the two engagement claws 24 (between the upper side and the lower side in FIG. 15).
  • Each contact claw 66 is provided with two projections 27 in the direction of the central axis 220a.
  • the protrusion 27 is formed in a protruding shape along the direction of the central axis 220a as in the above embodiment. Further, the four protrusions 27 are arranged so that two each face each other as in the above embodiment.
  • the four protrusions 27 are formed at intervals of 90 degrees around the central axis 220a in plan view.
  • the stopper 220 having such a configuration, since only two engagement claws 24 are provided, the engagement with the holder main body 40 is easy and the assembly is excellent.
  • the width D3 of the engaging claw 24 is preferably set between 3 mm and 5 mm.
  • a stopper 221 provided with three engagement claws 24 and three contact claws 26 may be used.
  • the three engaging claws 24 are arranged at equal intervals along the outer periphery of the lid portion 53. In other words, the three engaging claws 24 are provided at intervals of 120 degrees around the central axis 221a in plan view.
  • a contact claw 26 is provided between the engagement claws 24.
  • the assemblability is better than in the case of four engaging claws 24. Furthermore, the configuration with three engagement claws 24 is less likely to cause the inclination of the engagement claws 24 than the configuration with two engagement claws 24.
  • the number of engagement claws 24 and the number of contact claws 26 are not limited to the numbers 2 to 4 in FIGS. 10, 15, and 16, and may be 5 or more.
  • claw 26 is the structure which has the permite
  • a stopper 222 configured as shown in FIG. 17 may be used.
  • a contact claw 76 that is not provided with the protrusion 27 is provided.
  • the abutment claw 76 is formed such that the central portion in the width direction protrudes inwardly in plan view. The projecting central portion 76a contacts the cartridge preparation 21.
  • a stopper 223 configured as shown in FIG. 18 may be used.
  • the contact claw 86 of the stopper 223 shown in FIG. 18 is different from the contact claw 76 of the stopper 222 shown in FIG. 17 in that the central portion 76a is not formed and a flat surface 86a is formed inside.
  • the flat surface 86 a comes into contact with the outer surface of the cartridge preparation 21.
  • the protrusion includes the shape of the protrusion as in the contact claw 76 in FIG. 17, and the inner side thereof is formed in a triangular shape, or is formed in a planar shape as in the contact claw 86 in FIG.
  • the strength can be improved as compared with the case where the protrusion 27 is provided. Further, since the strength is improved, the length of the contact claws 76 and 86 in the axial direction (length in the front-rear direction) can be increased, and the degree of dimensional freedom can be increased. Further, in the case of the contact claw shown in FIGS. 17 and 18, since the shape can be simplified as compared with the contact claw 26 of the embodiment, the processing becomes easy and the cost can be reduced.
  • FIG. 19A is a plan view of the stopper 100 of the cartridge holder in which the engaging claw 24 and the contact claw 26 are connected.
  • FIG. 19B is a cross-sectional view taken along the DD ′ line in FIG.
  • the stopper 100 unlike the stopper 22 of the embodiment, the engagement claw 24 and the contact claw 26 are connected, and one cylindrical portion 101 is formed. Is formed.
  • the stopper 100 is connected so as to connect a part of the engagement support part 240 (a part below the part where the claw part 241 is provided) and a part excluding the protrusion 27 of the contact claw 26.
  • a portion 102 is formed, and a cylindrical portion 101 is formed by a part of the engagement support portion 240, the contact support portion 260 of the contact claw 26, and the connecting portion 102.
  • the connecting portion 102 that connects the engaging claw 24 and the contact claw 26 is provided along the outer periphery of the lid portion 53.
  • the cylindrical part 101 is provided, a part of the cylindrical part 101 is used as a part of the contact claw 26, and a part is used as a part of the engaging claw 24.
  • the strength can be improved.
  • the length from the lid portion 53 to the tip of the engagement support portion 240 is L1
  • the length from the lid portion 53 of the cylindrical portion 101 is L2
  • the difference between L1 and L2 is 3 mm to 10 mm. .
  • FIG. 20A is a plan view of the stopper 110 having a configuration in which a part of the locking claw and a part of the abutment claw are combined.
  • FIG. 20B is a cross-sectional view taken along the line EE ′ in FIG.
  • the stopper 110 shown in FIGS. 20A and 20B four engagement claws 24 are provided, and the engagement support portions 240 are provided inside the engagement support portions 240 of the respective engagement claws 24.
  • a protrusion 27 is formed along the line. The protrusion 27 is not formed up to the tip portion where the claw portion 241 of the engagement support portion 240 is formed. That is, the contact support portion 260 of the contact claw 26 in the above embodiment also serves as the engagement support portion 240 of the engagement claw 24.
  • the four engaging claws 24 are provided along the outer periphery of the lid portion 53 at a predetermined interval, and have the engaging support portion 240 and the claw portion 241. is doing.
  • the engagement support portion 240 is formed so as to protrude from the lid portion 53.
  • the claw portion 241 is provided at the tip of the engagement support portion 240 and is engaged with the engagement opening portion 25.
  • the contact claw 26 has a contact support portion 260 and a protrusion 27.
  • the contact support portion 260 is formed so as to protrude from the lid portion 53.
  • the protrusion 27 is formed inward from the contact support portion 260.
  • the contact support portion 260 is also used as the engagement support portion 240.
  • the shape can be simplified and manufacturing can be easily performed.
  • the difference between L1 and L2 is preferably 3 mm to 10 mm.
  • the cartridge holder and the cartridge holder unit of the present invention have an effect capable of reducing damage to the cartridge preparation due to dropping or the like, and are expected to be used as a medicine injection device.

Abstract

The present invention pertains to a cartridge holder and has, as the objective, preventing damage to a cartridge formulation resulting from dropping or the like. Also, in order to achieve the objective, the present invention is a cartridge holder (30) that holds a cartridge formulation (21), is mounted to a drug injection device, and has a holder main body (40) and a stopper (22). The holder main body (40) has an aperture section (17) that is at the rear end side of the holder main body and to which the cartridge formulation (21) is inserted. The stopper (22) has a piston-insertion aperture section (23) to which a piston (14) for drug injection is inserted, and the stopper (22) is mounted to the aperture section (17) at the rear end side of the holder main body (40) in order to hold the cartridge formulation (21) within the holder main body (40).

Description

カートリッジホルダ、カートリッジユニット、及びカートリッジユニットが装着される薬剤注入装置Cartridge holder, cartridge unit, and medicine injection device to which cartridge unit is attached
　本発明は、カートリッジホルダ、カートリッジユニット、及びカートリッジユニットが装着される薬剤注入装置に関するものである。 The present invention relates to a cartridge holder, a cartridge unit, and a medicine injection device to which the cartridge unit is attached.
　従来のこの種の薬剤注入装置として、以下のような構成が開示されている。
　例えば、薬剤が予め充填されているシリンジ製剤が挿入されるホルダと、このホルダの末端に固定される調剤装置と、調剤装置に接続された薬液定量注入器とを備えた薬剤注入装置の構成が開示されている（例えば、特許文献１参照）。
　このような構成の薬剤注入装置は、シリンジ製剤をホルダ内に挿入し、ホルダに調剤装置及び薬剤定量注入器を接続して組み立てられた状態で病院または患者に提供される。
　そして、医師又は患者等の使用者がピストンを駆動させることによってシリンジ製剤内の製剤がシリンジ製剤の先端側に装着された注射針から人体等に注入される。
　このように、ピストンを駆動させることで、シリンジ製剤内の製剤を自動的に人体等に注入することが出来るので、極めて利便性の高いものであった。
　上記特許文献１の薬剤注入装置は一般的に使い捨てであるが、交換可能なカートリッジ製剤を用いた薬剤注入装置も使用されている。このような薬剤注入装置では、カートリッジを装着後、薬剤注入装置に設けられているピストンがカートリッジ製剤に挿入され、薬剤の注入が行われる。そして、カートリッジ製剤の中身がなくなると、使用者が新たなカートリッジ製剤を装着することにより、薬剤の注入を行うことが出来る。 The following configuration is disclosed as a conventional drug injection device of this type.
For example, a configuration of a drug injection device including a holder into which a syringe preparation pre-filled with a drug is inserted, a dispensing device fixed to the end of the holder, and a chemical liquid metering injector connected to the dispensing device. It is disclosed (for example, see Patent Document 1).
The drug injection device having such a configuration is provided to a hospital or a patient in a state in which a syringe preparation is inserted into a holder and a dispensing device and a drug metering injector are connected to the holder and assembled.
Then, a user such as a doctor or a patient drives the piston to inject the preparation in the syringe preparation into a human body or the like from the injection needle attached to the distal end side of the syringe preparation.
In this way, by driving the piston, the preparation in the syringe preparation can be automatically injected into the human body or the like, which is extremely convenient.
The drug injection device of Patent Document 1 is generally disposable, but a drug injection device using a replaceable cartridge preparation is also used. In such a drug injection device, after mounting the cartridge, a piston provided in the drug injection device is inserted into the cartridge preparation, and drug injection is performed. When the contents of the cartridge preparation disappear, the user can inject the medicine by mounting a new cartridge preparation.
特開平１１－７６４０４号公報Japanese Patent Laid-Open No. 11-76404
（発明が解決しようとする課題）
　しかしながら、市販されているカートリッジ製剤は、例えば、ガラスで形成された円筒状となっているため、これを薬剤注入装置に装着する作業時等に誤って落下させると、カートリッジ製剤が損傷してしまうという課題があった。
　そこで、本発明の目的は、従来のカートリッジ製剤の課題を考慮し、落下等によるカートリッジ製剤の損傷を低減することが可能なカートリッジホルダ、カートリッジユニット及び薬剤注入装置を提供することである。 (Problems to be solved by the invention)
However, since the commercially available cartridge preparation has a cylindrical shape made of glass, for example, if the cartridge preparation is accidentally dropped at the time of attaching the medicine injection apparatus, the cartridge preparation is damaged. There was a problem.
Accordingly, an object of the present invention is to provide a cartridge holder, a cartridge unit, and a medicine injection device capable of reducing damage to the cartridge preparation due to dropping or the like in consideration of the problems of the conventional cartridge preparation.
　そして、この目的を達成するために、本発明のカートリッジホルダは、薬剤入りのカートリッジを保持し、薬剤注入装置に装着されるカートリッジホルダであって、ホルダ本体と、ストッパとを備える。ホルダ本体は、カートリッジが挿入される第１開口部と、側面に設けられた被係合部とを有する筒状である。ストッパは、薬剤注入装置に設けられた薬剤注入用のピストンが挿入される第２開口部と、ホルダ本体に装着するために第２開口部の周囲から突出して形成され、被係合部と係合する係合爪とを有し、ホルダ本体内にカートリッジを保持するためにホルダ本体の第１開口部に装着される。
（発明の効果）
　本発明によれば、落下等による製剤シリンジの損傷を低減することが可能なカートリッジホルダ、カートリッジユニット及び薬剤注入装置を提供することが出来る。 In order to achieve this object, the cartridge holder of the present invention is a cartridge holder that holds a cartridge containing a medicine and is attached to the medicine injection device, and includes a holder body and a stopper. The holder body has a cylindrical shape having a first opening into which the cartridge is inserted and an engaged portion provided on the side surface. The stopper is formed with a second opening into which a drug injection piston provided in the drug injection device is inserted, and protrudes from the periphery of the second opening to be attached to the holder body. An engaging claw for mating, and is mounted in the first opening of the holder body to hold the cartridge in the holder body.
(The invention's effect)
ADVANTAGE OF THE INVENTION According to this invention, the cartridge holder, cartridge unit, and chemical | medical agent injection apparatus which can reduce the damage of the preparation syringe by fall etc. can be provided.
本発明にかかる実施の形態における薬剤注入装置を示す斜視図The perspective view which shows the chemical injection device in embodiment concerning this invention 図１の薬剤注入装置の分解斜視図1 is an exploded perspective view of the drug injection device of FIG. 図１の薬剤注入装置の動作状態を示すための断面図Sectional drawing for demonstrating the operation state of the chemical | medical agent injection apparatus of FIG. 図１の薬剤注入装置に装着されるカートリッジユニットの斜視図The perspective view of the cartridge unit with which the chemical | medical agent injection apparatus of FIG. 1 is mounted | worn 図４のカートリッジユニットの分解斜視図4 is an exploded perspective view of the cartridge unit of FIG. 図４のカートリッジユニットの分解斜視図4 is an exploded perspective view of the cartridge unit of FIG. 図４のカートリッジユニットの断面図Sectional view of the cartridge unit of FIG. 図４のカートリッジユニットを構成するストッパの斜視図The perspective view of the stopper which comprises the cartridge unit of FIG. 図８のストッパの断面図Sectional view of the stopper of FIG. 図８のストッパの平面図Plan view of the stopper of FIG. 図４のカートリッジユニットの後端近傍を示す断面図Sectional drawing which shows the rear end vicinity of the cartridge unit of FIG. （ａ）図４のカートリッジユニットの位置決め部近傍を示す断面図、（ｂ）図４のカートリッジユニットのカートリッジ保持部近傍を示す平面図4A is a sectional view showing the vicinity of the positioning portion of the cartridge unit of FIG. 4, and FIG. 4B is a plan view showing the vicinity of the cartridge holding portion of the cartridge unit of FIG. 本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す断面図Sectional drawing which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention 本発明にかかる実施の形態の変形例におけるカートリッジユニットの後端近傍を示す断面図Sectional drawing which shows the rear end vicinity of the cartridge unit in the modification of embodiment concerning this invention 本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパの変形例を示す平面図The top view which shows the modification of the stopper of the cartridge unit in the modification of embodiment concerning this invention 本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す平面図The top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention 本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す平面図The top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention 本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す平面図The top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention （ａ）本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す平面図、（ｂ）図１９（ａ）のＤＤ´間断面図(A) Top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention, (b) DD 'sectional drawing of Fig.19 (a) （ａ）本発明にかかる実施の形態の変形例におけるカートリッジユニットのストッパを示す平面図、（ｂ）図２０（ａ）のＥＥ´間断面図(A) Top view which shows the stopper of the cartridge unit in the modification of embodiment concerning this invention, (b) Sectional drawing between EE 'of Fig.20 (a).
　以下、本発明の実施の形態について図面を参照して詳細に説明する。
（実施の形態１）
　＜構成＞
　（薬剤注入装置の外観構成）
　図１は、本実施の形態の薬剤注入装置の外観を示す斜視図である。又、図２は、本実施の形態の薬剤注入装置の分解斜視図である。尚、以下の説明において、先端側又は前端側とは、薬剤が注入される方向（開口部９側）を示し、後端側とは、その反対方向（電源ボタン５側）のことを示す。 Hereinafter, embodiments of the present invention will be described in detail with reference to the drawings.
(Embodiment 1)
<Configuration>
(Appearance structure of drug injection device)
FIG. 1 is a perspective view showing the appearance of the drug injection device of the present embodiment. FIG. 2 is an exploded perspective view of the drug injection device according to the present embodiment. In the following description, the front end side or the front end side indicates the direction in which the medicine is injected (opening 9 side), and the rear end side indicates the opposite direction (the power button 5 side).
　図１及び図２に示すように、薬剤注入装置は、本体ケース１を有している。図１及び図２において、この本体ケース１の前面側には表示部２が設けられ、この表示部２の側方には、エアー抜きボタン３及び完了ボタン４が設けられている。
　また、図１において表示部２の右方側であって本体ケース１の後端側には電源ボタン５が設けられている。さらに表示部２の左方側であって本体ケース１の前端側には薬剤注入ボタン６が設けられている。 As shown in FIGS. 1 and 2, the drug injection device has a main body case 1. 1 and 2, a display unit 2 is provided on the front side of the main body case 1, and an air vent button 3 and a completion button 4 are provided on the side of the display unit 2.
Further, a power button 5 is provided on the right side of the display unit 2 in FIG. Further, a medicine injection button 6 is provided on the left side of the display unit 2 and on the front end side of the main body case 1.
　また、図１及び図２に示すように本体ケース１の前端側には先端キャップ７が着脱自在に装着されている。先端キャップ７には、図１において前面側に確認窓８が設けられている。先端キャップ７の前端側には、図２に示すように開口部９が設けられている。
　この図１において、確認窓８から見える先端キャップ７内の部分には、カートリッジ製剤２１及びカートリッジホルダ３０で構成されるカートリッジユニット１０が装着されている。また、カートリッジユニット１０の前端側に装着される注射針１２を保護する針キャップ１１が図示されている。 Further, as shown in FIGS. 1 and 2, a front end cap 7 is detachably attached to the front end side of the main body case 1. The tip cap 7 is provided with a confirmation window 8 on the front side in FIG. An opening 9 is provided on the front end side of the tip cap 7 as shown in FIG.
In FIG. 1, a cartridge unit 10 including a cartridge preparation 21 and a cartridge holder 30 is attached to a portion in the tip cap 7 that can be seen from the confirmation window 8. Further, a needle cap 11 that protects the injection needle 12 attached to the front end side of the cartridge unit 10 is shown.
　カートリッジユニット１０を薬剤注入装置に装着する際には、図１のように本体ケース１に取り付けられている先端キャップ７が本体ケース１から取り外される。そして、その状態で、カートリッジユニット１０が、その後端側から本体ケース１の装着部１３（図２参照）に装着され、また、針キャップ１１がカートリッジユニット１０の先端側に装着される。その後、先端キャップ７が本体ケース１に取り付けられる。 When the cartridge unit 10 is attached to the drug injection device, the tip cap 7 attached to the main body case 1 is removed from the main body case 1 as shown in FIG. In this state, the cartridge unit 10 is mounted on the mounting portion 13 (see FIG. 2) of the main body case 1 from the rear end side, and the needle cap 11 is mounted on the front end side of the cartridge unit 10. Thereafter, the tip cap 7 is attached to the main body case 1.
　（薬剤注入装置の内部構成）
　図３は、本実施の形態の薬剤注入装置の動作状態を示すための断面図である。図３に示すように、薬剤注入装置は、装着部１３と、ピストン１４と、モータ１５と、ピストン固定部２９とを備えている。装着部１３は本体ケース１内に設けられたインナーケースであって、カートリッジユニット１０を薬剤注入装置に装着した際には、カートリッジユニット１０は、この装着部１３内に装着された状態となる。 (Internal configuration of drug injection device)
FIG. 3 is a cross-sectional view for illustrating an operating state of the pharmaceutical injection device according to the present embodiment. As shown in FIG. 3, the drug injection device includes a mounting portion 13, a piston 14, a motor 15, and a piston fixing portion 29. The mounting portion 13 is an inner case provided in the main body case 1. When the cartridge unit 10 is mounted on the drug injection device, the cartridge unit 10 is mounted in the mounting portion 13.
　ピストン１４は、カートリッジユニット１０のカートリッジ製剤２１内に挿入され、それによって、カートリッジ製剤２１内の製剤が注射針１２を介して人体等に注入される。
　ピストン固定部２９は、ピストン１４の位置を固定するものであり、カートリッジユニット１０に対して位置が固定されている。
　モータ１５は、注射針１２側にピストン１４を押し込むためにピストン１４を駆動する。 The piston 14 is inserted into the cartridge preparation 21 of the cartridge unit 10, whereby the preparation in the cartridge preparation 21 is injected into the human body or the like via the injection needle 12.
The piston fixing part 29 fixes the position of the piston 14, and the position is fixed with respect to the cartridge unit 10.
The motor 15 drives the piston 14 to push the piston 14 toward the injection needle 12 side.
　（カートリッジユニット１０の構成）
　次に、本実施の形態のカートリッジユニット１０の構成について、図４から図１０を用いて詳細に説明する。図４は、本実施の形態のカートリッジユニット１０の斜視図である。図５は、本実施の形態のカートリッジユニット１０の分解斜視図である。図６は、図５とは異なる方向から視たカートリッジユニット１０の分解斜視図である。図７は、本実施の形態のカートリッジユニット１０の断面図であり、図５のＡＡ´間の断面図である。また、後述する図１０にもＡＡ´が示されている。 (Configuration of cartridge unit 10)
Next, the configuration of the cartridge unit 10 of the present embodiment will be described in detail with reference to FIGS. FIG. 4 is a perspective view of the cartridge unit 10 of the present embodiment. FIG. 5 is an exploded perspective view of the cartridge unit 10 of the present embodiment. FIG. 6 is an exploded perspective view of the cartridge unit 10 viewed from a direction different from that in FIG. FIG. 7 is a cross-sectional view of the cartridge unit 10 of the present embodiment, and is a cross-sectional view taken along the line AA ′ of FIG. Further, AA ′ is also shown in FIG. 10 described later.
　図４～図７に示すように、本実施の形態のカートリッジユニット１０は、カートリッジ製剤２１と、カートリッジホルダ３０とを備えている。また、カートリッジホルダ３０は、ホルダ本体４０と、ストッパ２２とを有している。
　（ホルダ本体４０）
　図５～図７に示すように、ホルダ本体４０は、円筒形状であって、円筒部４１と、接続部４２と、位置決め部１８と、ホルダ本体先端側開口部１６と、ホルダ本体後端側開口部１７と、係合開口部２５を有している。 As shown in FIGS. 4 to 7, the cartridge unit 10 of the present embodiment includes a cartridge preparation 21 and a cartridge holder 30. The cartridge holder 30 includes a holder main body 40 and a stopper 22.
(Holder body 40)
As shown in FIGS. 5 to 7, the holder main body 40 has a cylindrical shape, and includes a cylindrical portion 41, a connection portion 42, a positioning portion 18, a holder main body front end side opening 16, and a holder main body rear end side. An opening 17 and an engagement opening 25 are provided.
　円筒部４１には、カートリッジ製剤２１が収納される。
　接続部４２は、円筒部４１の前端側に設けられており、円筒部４１よりも径が小さく、その外周側面にはネジ部が形成されている。このネジ部と針キャップ１１（図２参照）の内側に配置された注射針１２（図３参照）に形成されているネジ部が螺合し、針キャップ１１がホルダ本体４０に接続される。 In the cylindrical portion 41, the cartridge preparation 21 is stored.
The connecting portion 42 is provided on the front end side of the cylindrical portion 41, has a smaller diameter than the cylindrical portion 41, and has a screw portion formed on the outer peripheral side surface thereof. The screw portion and the screw portion formed on the injection needle 12 (see FIG. 3) arranged inside the needle cap 11 (see FIG. 2) are screwed together, and the needle cap 11 is connected to the holder body 40.
　位置決め部１８は、円筒部４１と接続部４２の間に設けられ、円筒部４１から接続部４２に向かって径が小さくなるテーパー状に形成されている。位置決め部１８は、カートリッジ製剤２１がホルダ本体４０に収納された状態において、後述するカートリッジ製剤２１の先端側当接部１９と当接する。
　ホルダ本体先端側開口部１６は、ホルダ本体４０の先端側（注射針１２が装着される注射針装着側ともいう）であって、接続部４２の内側に設けられており、注射針１２が接続される。 The positioning portion 18 is provided between the cylindrical portion 41 and the connection portion 42, and is formed in a tapered shape whose diameter decreases from the cylindrical portion 41 toward the connection portion 42. The positioning portion 18 abuts on a distal end side abutting portion 19 of the cartridge preparation 21 described later in a state where the cartridge preparation 21 is stored in the holder main body 40.
The holder main body front end side opening 16 is provided on the front end side of the holder main body 40 (also referred to as an injection needle mounting side on which the injection needle 12 is mounted), and is provided inside the connection portion 42. Is done.
　ホルダ本体後端側開口部１７は、ホルダ本体先端側開口部１６の反対側である後端側（ピストン挿入側ともいう）に設けられており、ストッパ２２が挿入される。
　係合開口部２５は、円筒部４１の側面を貫通して形成された孔であって、ホルダ本体後端側開口部１７寄りに周方向に沿って４箇所形成されている。この係合開口部２５には、後述するストッパ２２の係合爪２４が係合する。 The holder main body rear end side opening 17 is provided on the rear end side (also referred to as piston insertion side) opposite to the holder main body front end side opening 16, and the stopper 22 is inserted.
The engagement openings 25 are holes formed through the side surface of the cylindrical portion 41, and are formed at four locations along the circumferential direction near the holder body rear end side opening 17. An engagement claw 24 of a stopper 22 described later engages with the engagement opening 25.
　（カートリッジ製剤２１）
　カートリッジ製剤２１は、円筒状であって、上記ホルダ本体４０内に収納される。カートリッジ製剤２１には、例えば、インスリン等の注入用の薬剤が予め充填されている。
　図５～図７に示すように、カートリッジ製剤２１は、円筒部５１と、接続部５２と、先端側当接部１９と、カートリッジ開口部２０を有している。 (Cartridge formulation 21)
The cartridge preparation 21 is cylindrical and is accommodated in the holder body 40. For example, the cartridge preparation 21 is pre-filled with a medicine for injection such as insulin.
As shown in FIGS. 5 to 7, the cartridge preparation 21 has a cylindrical portion 51, a connection portion 52, a distal end side contact portion 19, and a cartridge opening 20.
　円筒部５１には、薬剤が充填される。
　接続部５２は、円筒部５１の前端側に設けられており、円筒部５１よりも径が小さく、その内側を通して注射針１２が接続される。図７に示すように、接続部５２には、ゴム状のキャップ部１５２が設けられており、カートリッジ製剤２１が封止されている。尚、カートリッジホルダ３０にカートリッジ製剤２１を収納した状態で針キャップ１１をホルダ本体４０に接続することによって、針キャップ１１内に配置されている注射針１２がホルダ本体先端側開口部１６を介してカートリッジ製剤２１の接続部５２に装着される。 The cylindrical part 51 is filled with a medicine.
The connecting portion 52 is provided on the front end side of the cylindrical portion 51, has a smaller diameter than the cylindrical portion 51, and the injection needle 12 is connected through the inside thereof. As shown in FIG. 7, the connection part 52 is provided with a rubber-like cap part 152, and the cartridge preparation 21 is sealed. In addition, by connecting the needle cap 11 to the holder main body 40 in a state in which the cartridge preparation 21 is stored in the cartridge holder 30, the injection needle 12 disposed in the needle cap 11 is inserted through the opening 16 on the distal end side of the holder main body. It is attached to the connection part 52 of the cartridge preparation 21.
　先端側当接部１９は、円筒部５１と接続部５２の間に設けられており、円筒部５１から接続部５２に向かって径が小さくなるテーパー形状に形成されている。カートリッジ製剤２１をホルダ本体４０に挿入すると、この先端側当接部１９が、テーパー形状の位置決め部１８に当接する。そして位置決め部１８に対して先端側当接部１９が滑ってホルダ本体４０の径方向の略中央でカートリッジ製剤２１が位置決めされる。このように、カートリッジホルダ３０に対するカートリッジ製剤２１の位置決めが行われる。 The front end side contact portion 19 is provided between the cylindrical portion 51 and the connection portion 52, and is formed in a tapered shape whose diameter decreases from the cylindrical portion 51 toward the connection portion 52. When the cartridge preparation 21 is inserted into the holder main body 40, the distal end side contact portion 19 comes into contact with the tapered positioning portion 18. Then, the front end side contact portion 19 slides with respect to the positioning portion 18, and the cartridge preparation 21 is positioned at a substantially center in the radial direction of the holder main body 40. Thus, positioning of the cartridge preparation 21 with respect to the cartridge holder 30 is performed.
　カートリッジ開口部２０は、カートリッジ製剤２１の後端に設けられており、ピストン１４が挿入される。カートリッジ開口部２０は、ガスケット１５３によって封止されている。ピストン挿入時には、このガスケット１５３が押され、円筒部５１内の薬剤が接続部５２に接続された注射針１２から注入される。 The cartridge opening 20 is provided at the rear end of the cartridge preparation 21 and the piston 14 is inserted therein. The cartridge opening 20 is sealed with a gasket 153. When the piston is inserted, the gasket 153 is pushed, and the medicine in the cylindrical part 51 is injected from the injection needle 12 connected to the connection part 52.
　（ストッパ２２）
　図３、図４及び図７に示すように、ストッパ２２は、ホルダ本体４０のホルダ本体後端側開口部１７の内方に装着されている。
　図８は、本実施の形態のストッパ２２の斜視図である。図９は、本実施の形態のストッパ２２の側断面図である。図１０は、本実施の形態のストッパ２２の平面図である。尚、図９は、図１０のＣＣ´間断面図である。尚、図１０では、カートリッジ製剤２１の後端の外周縁２１Ｔが二点鎖線で示されている。
　このストッパ２２は、合成樹脂で形成されており、ピストン１４よりも軟質に形成されている。そして、図８～図１０に示すように、ストッパ２２は、係合爪２４と、カートリッジ保持部５０を有する。 (Stopper 22)
As shown in FIGS. 3, 4, and 7, the stopper 22 is mounted inside the holder body rear end side opening 17 of the holder body 40.
FIG. 8 is a perspective view of the stopper 22 of the present embodiment. FIG. 9 is a side sectional view of the stopper 22 of the present embodiment. FIG. 10 is a plan view of the stopper 22 of the present embodiment. 9 is a cross-sectional view taken along CC ′ in FIG. In FIG. 10, the outer peripheral edge 21T at the rear end of the cartridge preparation 21 is indicated by a two-dot chain line.
The stopper 22 is made of synthetic resin and is softer than the piston 14. As shown in FIGS. 8 to 10, the stopper 22 has an engaging claw 24 and a cartridge holding part 50.
　（カートリッジ保持部５０）
　カートリッジ保持部５０は、カートリッジ製剤２１をカートリッジホルダ３０内に保持するものである。カートリッジ保持部５０には、蓋部５３と、当接爪２６が設けられている。 (Cartridge holder 50)
The cartridge holding unit 50 holds the cartridge preparation 21 in the cartridge holder 30. The cartridge holding portion 50 is provided with a lid portion 53 and a contact claw 26.
　（蓋部５３）
　蓋部５３は、円盤形状であり、その中央にピストン挿入開口部２３が設けられている。ストッパ２２がホルダ本体４０に装着された状態において、ピストン挿入開口部２３はカートリッジ製剤２１のカートリッジ開口部２０に対応する位置に配置され、薬剤注入時にピストン１４が挿入される。いいかえると、ストッパ２２がホルダ本体４０に装着された状態において、蓋部５３は、ピストン挿入開口部２３がカートリッジ開口部２０と対向するように配置される。
　また、図９に示すようにピストン挿入開口部２３の周縁２３ｅは、Ｒ形状に形成されている。 (Cover 53)
The lid 53 has a disk shape, and a piston insertion opening 23 is provided at the center thereof. In a state where the stopper 22 is mounted on the holder main body 40, the piston insertion opening 23 is disposed at a position corresponding to the cartridge opening 20 of the cartridge preparation 21, and the piston 14 is inserted at the time of drug injection. In other words, the lid 53 is arranged so that the piston insertion opening 23 faces the cartridge opening 20 in a state in which the stopper 22 is mounted on the holder main body 40.
Further, as shown in FIG. 9, the peripheral edge 23e of the piston insertion opening 23 is formed in an R shape.
　（当接爪２６）
　当接爪２６は、蓋部５３の外周縁に所定の間隔を設けて４つ設けられている。いいかえると、４つの当接爪２６は平面視において中心軸２２ａを中心として９０度間隔で配置されている。詳しく説明すると、この当接爪２６には、蓋部５３の外周縁から蓋部５３に対して略垂直方向に形成された当接支持部２６０と、当接支持部２６０から内側に向かって突出して形成された突起２７が設けられている。この当接支持部２６０は、蓋部５３の外周縁に沿って湾曲された板状の部材である。突起２７は、中心軸２２ａ（図１０参照）に向かって突出しており、図８に示すように当接支持部２６０に沿って前後方向に突状に形成されている。
　図１１は、カートリッジ製剤２１が挿入されたホルダ本体４０にストッパ２２を装着した状態のストッパ２２の周辺部を示す断面図である。図７、図１０及び図１１に示すように、カートリッジ製剤２１が当接爪２６の突起２７の間に挟まるように配置されるとともに、蓋部５３によってホルダ本体後端側開口部１７への移動が規制され、カートリッジ製剤２１がカートリッジホルダ３０内に保持される。 (Abutment claw 26)
Four contact claws 26 are provided at a predetermined interval on the outer peripheral edge of the lid portion 53. In other words, the four contact claws 26 are arranged at intervals of 90 degrees around the central axis 22a in plan view. More specifically, the contact claw 26 protrudes inward from the contact support portion 260 and a contact support portion 260 formed in a direction substantially perpendicular to the cover portion 53 from the outer peripheral edge of the cover portion 53. A projection 27 is formed. The contact support portion 260 is a plate-like member that is curved along the outer peripheral edge of the lid portion 53. The protrusion 27 protrudes toward the central axis 22a (see FIG. 10), and is formed in a protruding shape in the front-rear direction along the contact support portion 260 as shown in FIG.
FIG. 11 is a cross-sectional view showing a peripheral portion of the stopper 22 in a state where the stopper 22 is mounted on the holder main body 40 in which the cartridge preparation 21 is inserted. As shown in FIGS. 7, 10, and 11, the cartridge preparation 21 is disposed so as to be sandwiched between the protrusions 27 of the contact claw 26, and moved to the holder body rear end side opening 17 by the lid 53. The cartridge preparation 21 is held in the cartridge holder 30.
　（係合爪２４）
　係合爪２４は、蓋部５３の外周縁に所定の間隔を空けて４つ設けられている。いいかえると、４つの係合爪２４は平面視において中心軸２２ａを中心として９０度間隔で配置されている。それぞれの係合爪２４は、当接爪２６の間に設けられている。詳しく説明すると、図８、図９に示すように係合爪２４は、蓋部５３の外周縁から蓋部５３に対して略垂直方向に形成された係合支持部２４０と、係合支持部２４０の先端部分の外側に設けられ、係合支持部２４０によって支持されている爪部２４１とを有している。 (Engagement claw 24)
Four engagement claws 24 are provided on the outer peripheral edge of the lid 53 with a predetermined interval. In other words, the four engaging claws 24 are arranged at intervals of 90 degrees around the central axis 22a in plan view. Each engagement claw 24 is provided between the contact claws 26. More specifically, as shown in FIGS. 8 and 9, the engagement claw 24 includes an engagement support portion 240 formed in a substantially vertical direction from the outer peripheral edge of the lid portion 53 to the lid portion 53, and an engagement support portion. The claw portion 241 is provided outside the front end portion of the 240 and supported by the engagement support portion 240.
　係合支持部２４０は、蓋部５３の外周縁に沿って湾曲された板状の部材であり、当接支持部２６０よりも長く形成されている。爪部２４１は、図９に示すように係合支持部２４０の先端から蓋部５３に向かうに従って外側に向かって突出する長さが長くなるように、その外周側に傾斜面２４１ａが形成されている。また、爪部２４１の下端、すなわち傾斜面２４１ａの下端から係合支持部２４０の間には、係合面２４１ｂが形成されている。この係合面２４１ｂが係合開口部２５の後端側の縁に当接し、爪部２４１が係合開口部２５に係合する（図４参照）。又、図９に示すように、係合面２４１ｂは、係合支持部２４０の外側面との間の角θが鋭角に形成されている。ストッパ２２がホルダ本体４０から外れる方向（図１１における矢印Ｂ）に力を受けた時、係合爪２４が中心側に撓もうとするが、角θを鋭角にすることにより爪部２４１が係合開口部２５から外れ難くすることが出来る。 The engagement support portion 240 is a plate-like member that is curved along the outer peripheral edge of the lid portion 53, and is formed longer than the contact support portion 260. As shown in FIG. 9, the claw portion 241 has an inclined surface 241 a formed on the outer peripheral side so that the length of the claw portion 241 protrudes outward from the end of the engagement support portion 240 toward the lid portion 53. Yes. An engagement surface 241b is formed between the lower end of the claw portion 241, that is, between the lower end of the inclined surface 241 a and the engagement support portion 240. The engagement surface 241b contacts the edge on the rear end side of the engagement opening 25, and the claw 241 engages with the engagement opening 25 (see FIG. 4). Further, as shown in FIG. 9, the engagement surface 241 b is formed with an acute angle θ with the outer surface of the engagement support portion 240. When the stopper 22 receives a force in a direction away from the holder main body 40 (arrow B in FIG. 11), the engaging claw 24 tries to bend toward the center, but the claw 241 is engaged by making the angle θ an acute angle. It can be made difficult to come off from the joint opening 25.
　また、傾斜面２４１ａを設けることにより、係合爪２４をホルダ本体４０に挿入する際にスムーズに入れることが可能になる。
　このように、ストッパ２２は、ピストン挿入開口部２３を有し、このピストン挿入開口部２３が形成されている蓋部５３の外周縁には、ホルダ本体４０のホルダ本体後端側開口部１７内に挿入される係合爪２４が設けられている。そして、この係合爪２４の外周方向に対応するホルダ本体４０の側面部分には、この係合爪２４が係合する係合開口部２５が設けられている。 Further, by providing the inclined surface 241a, the engaging claw 24 can be smoothly inserted when inserted into the holder main body 40.
As described above, the stopper 22 has the piston insertion opening 23, and the inner periphery of the holder main body rear end side opening 17 of the holder main body 40 is provided on the outer peripheral edge of the lid 53 where the piston insertion opening 23 is formed. An engaging claw 24 to be inserted into the is provided. An engagement opening 25 to which the engagement claw 24 engages is provided on the side surface portion of the holder main body 40 corresponding to the outer peripheral direction of the engagement claw 24.
　すなわち、本実施形態においては、カートリッジ製剤２１は、カートリッジホルダ３０内に装着された状態で、保管・携帯・薬剤注入装置への装着が行なわれるようになっている。
　また、カートリッジ製剤２１は、その先端側に、ホルダ本体先端側開口部１６の内方に設けた位置決め部１８に当接される先端側当接部１９を有し、その後端側には、ピストン１４が挿入されるカートリッジ開口部２０を有する構成を備えている。 In other words, in the present embodiment, the cartridge preparation 21 is mounted on the storage / portable / pharmaceutical injection device while being mounted in the cartridge holder 30.
Further, the cartridge preparation 21 has a distal end side contact portion 19 that is in contact with a positioning portion 18 provided inside the holder body distal end side opening 16 on the distal end side, and a piston end on the rear end side. 14 is provided with a cartridge opening 20 into which 14 is inserted.
　さらに、本実施の形態のカートリッジユニット１０では、ホルダ本体後端側開口部１７の内方にはストッパ２２が装着されている。このストッパ２２は、カートリッジ製剤２１のカートリッジ開口部２０に対応する部分に、ピストン挿入開口部２３を有している。このピストン挿入開口部２３の外周縁には、ホルダ本体４０のホルダ本体後端側開口部１７内に挿入される係合爪２４が設けられている。この係合爪２４の外周方向に対応するホルダ本体４０の部分には、この係合爪２４が係合する係合開口部２５が設けられている。 Furthermore, in the cartridge unit 10 of the present embodiment, a stopper 22 is mounted inside the holder body rear end opening 17. The stopper 22 has a piston insertion opening 23 at a portion corresponding to the cartridge opening 20 of the cartridge preparation 21. An engagement claw 24 to be inserted into the holder main body rear end side opening 17 of the holder main body 40 is provided on the outer peripheral edge of the piston insertion opening 23. In the portion of the holder main body 40 corresponding to the outer peripheral direction of the engagement claw 24, an engagement opening 25 to which the engagement claw 24 is engaged is provided.
　このため、カートリッジ製剤２１は、常時、カートリッジホルダ３０内に装着された状態となっており、この結果として、保管・携帯・薬剤注入装置への装着時等に、誤って、それを落下させたとしても、カートリッジ製剤２１の損傷を防止することができる。 For this reason, the cartridge preparation 21 is always mounted in the cartridge holder 30. As a result, the cartridge preparation 21 was accidentally dropped during storage, carrying, or mounting on the drug injection device. Even so, damage to the cartridge preparation 21 can be prevented.
　（組み立て動作）
　次に、カートリッジユニット１０の組立て動作について説明する。
　カートリッジ製剤２１、ホルダ本体４０及びストッパ２２を組み合わせてカートリッジユニット１０を作成する場合、ホルダ本体４０にカートリッジ製剤２１が挿入される。ホルダ本体後端側開口部１７からカートリッジ製剤２１をホルダ本体４０に挿入すると、テーパー形状である先端側当接部１９と、テーパー形状である位置決め部１８が当接する。その状態から、先端側当接部１９と位置決め部１８同士が滑り、カートリッジ製剤２１がホルダ本体４０内の径方向における略中央に位置決めされる。いいかえると、カートリッジ製剤２１の中心軸とホルダ本体４０の中心軸がほぼ重なった状態となる。 (Assembly operation)
Next, the assembly operation of the cartridge unit 10 will be described.
When the cartridge unit 10 is formed by combining the cartridge preparation 21, the holder body 40 and the stopper 22, the cartridge preparation 21 is inserted into the holder body 40. When the cartridge preparation 21 is inserted into the holder main body 40 from the holder main body rear end side opening 17, the tapered front end side contact portion 19 and the tapered positioning portion 18 come into contact. From this state, the tip-side contact portion 19 and the positioning portion 18 slide together, and the cartridge preparation 21 is positioned approximately at the center in the radial direction in the holder main body 40. In other words, the central axis of the cartridge preparation 21 and the central axis of the holder body 40 are substantially overlapped.
　次に、ストッパ２２がホルダ本体後端側開口部１７を塞ぐようにホルダ本体４０内に挿入される。
　ストッパ２２をホルダ本体４０の内側に挿入する際には、係合爪２４の傾斜面２４１ａが、ホルダ本体後端側開口部１７の縁１７ａ（図５参照）に当接する。更にストッパ２２をホルダ本体４０に押し込むと、係合支持部２４０が内側（図１１の矢印Ｂ参照）に向かって撓むことによって爪部２４１が縁１７ａに沿ってホルダ本体４０の内側に入り込む。 Next, the stopper 22 is inserted into the holder main body 40 so as to close the holder main body rear end side opening 17.
When the stopper 22 is inserted inside the holder main body 40, the inclined surface 241a of the engaging claw 24 abuts on the edge 17a (see FIG. 5) of the holder main body rear end side opening 17. When the stopper 22 is further pushed into the holder main body 40, the engagement support portion 240 bends inward (see arrow B in FIG. 11), so that the claw portion 241 enters the inside of the holder main body 40 along the edge 17a.
　ストッパ２２をホルダ本体４０に押し込むに従って、当接爪２６の間にカートリッジ製剤２１の後端部分が嵌りこむ。
　そして、爪部２４１が係合開口部２５に係合するとともに係合支持部２４０の撓みが解除される。
　以上のように、カートリッジユニット１０が組み立てられる。 As the stopper 22 is pushed into the holder body 40, the rear end portion of the cartridge preparation 21 is fitted between the contact claws 26.
And the nail | claw part 241 engages with the engagement opening part 25, and the bending of the engagement support part 240 is cancelled | released.
As described above, the cartridge unit 10 is assembled.
　（組み立てた状態のカートリッジユニット１０の構成）
　次に、組み立てられたカートリッジユニット１０の構成について説明するとともに、各部の構成についても、さらに詳細に説明する。
　本実施の形態のカートリッジユニット１０では、ホルダ本体４０の位置決め部１８と、ストッパ２２の蓋部５３及び当接爪２６とによってカートリッジ製剤２１がカートリッジホルダ３０内で所定の位置に保持されている。 (Configuration of cartridge unit 10 in an assembled state)
Next, the structure of the assembled cartridge unit 10 will be described, and the structure of each part will be described in more detail.
In the cartridge unit 10 of the present embodiment, the cartridge preparation 21 is held at a predetermined position in the cartridge holder 30 by the positioning portion 18 of the holder main body 40, the lid portion 53 of the stopper 22, and the contact claw 26.
　ここで、ホルダ本体４０内において、カートリッジ製剤２１の先端側は、段部による位置決め部１８において、ホルダ先端側に、このカートリッジ製剤２１の先端側外周面の少なくとも一部において、ホルダ本体４０の内周面との間に隙間を介して保持された構造となっている。
　図１２（ａ）を用いて詳しく説明する。図１２（ａ）は、位置決め部１８及び先端側当接部１９の近傍を示す断面図である。テーパー形状の位置決め部１８は、ホルダ本体先端側開口部１６の周囲に一周にわたって形成されている。また、テーパー形状の先端側当接部１９も、接続部５２の周囲に一周にわたって形成されている。位置決め部１８の先端側当接部１９への当接により、カートリッジ製剤２１がカートリッジホルダ３０に保持されているが、この位置決め部１８と先端側当接部１９の間の少なくとも一部には、Ｐ部拡大図に示すように隙間Ｓ１が設けられている。この微少な隙間Ｓ１は薬剤を注入する際、ピストン１４がガスケット１５３を押す事で無くなり、カートリッジ製剤２１が長手方向に精度良く位置決めされる。 Here, in the holder main body 40, the front end side of the cartridge preparation 21 is located on the holder front end side in the positioning portion 18 by the stepped portion, and at least a part of the outer peripheral surface of the front end side of the cartridge preparation 21 in the holder main body 40. It has a structure held via a gap between the peripheral surface.
This will be described in detail with reference to FIG. FIG. 12A is a cross-sectional view showing the vicinity of the positioning portion 18 and the distal end side contact portion 19. The tapered positioning portion 18 is formed around the circumference of the holder body distal end side opening portion 16 over the entire circumference. Further, the tapered tip side contact portion 19 is also formed around the connection portion 52 over the entire circumference. The cartridge preparation 21 is held in the cartridge holder 30 by the contact of the positioning portion 18 with the distal end side contact portion 19, but at least a part between the positioning portion 18 and the distal end side contact portion 19 is As shown in the enlarged view of the P portion, a gap S1 is provided. The minute gap S1 disappears when the drug is injected, and the piston 14 presses the gasket 153, and the cartridge preparation 21 is accurately positioned in the longitudinal direction.
　また、カートリッジ製剤２１の後端側外周面の少なくとも一部において、ストッパ２２の内周面との間に隙間を介して保持された構造となっている。
　図１２（ｂ）を用いて詳しく説明する。図１２（ｂ）は、カートリッジ製剤２１の後端部分を示す平面図である。当接爪２６の突起２７のカートリッジ製剤２１の外周面への当接により、カートリッジ製剤２１がカートリッジホルダ３０に保持されているが、カートリッジ製剤２１の外周面２１ａと、４つの突起２７のうちの少なくとも１つの突起２７との間には、Ｑ部拡大図に示すように隙間Ｓ２が設けられている。 Further, at least a part of the outer peripheral surface on the rear end side of the cartridge preparation 21 is held between the inner peripheral surface of the stopper 22 via a gap.
This will be described in detail with reference to FIG. FIG. 12B is a plan view showing the rear end portion of the cartridge preparation 21. The cartridge preparation 21 is held by the cartridge holder 30 by the contact of the protrusion 27 of the contact claw 26 with the outer peripheral surface of the cartridge preparation 21, but the outer peripheral surface 21 a of the cartridge preparation 21 and the four protrusions 27 A gap S2 is provided between at least one protrusion 27 as shown in the enlarged view of the Q portion.
　このように、カートリッジ製剤２１は、カートリッジホルダ３０内において、先端側も後端側も若干の隙間を介して保持された状態となっているので、落下等によりカートリッジホルダ３０に加わる衝撃が直接的にカートリッジ製剤２１に加わることはなく、この点からも、衝撃に対する強度の強いものとなる。
　また、図４及び図１１に示すように、本実施の形態のカートリッジユニット１０では、ストッパ２２の蓋部５３がホルダ本体４０の後端である縁１７ａより内側に入り込んでいる。 Thus, since the cartridge preparation 21 is held in the cartridge holder 30 through the slight gap on both the front end side and the rear end side, the impact applied to the cartridge holder 30 due to dropping or the like is directly applied. In this respect, the strength against impact is strong.
As shown in FIGS. 4 and 11, in the cartridge unit 10 of the present embodiment, the lid portion 53 of the stopper 22 enters inside the edge 17 a that is the rear end of the holder body 40.
　このため、カートリッジユニット１０をストッパ２２側から落下させたとしても、ホルダ本体４０の後端である縁１７ａが地面に接触することになり、落下などによる破損を低減することが出来る。
　また、図１１に示すように、係合開口部２５が爪部２４１よりも前後方向に大きく形成されているため、係合開口部２５内を爪部２４１が前後方向に移動可能である。そのため、落下した際にカートリッジ製剤２１と蓋部５３が当接している場合であっても、カートリッジ製剤２１はストッパ２２とともに長手方向に若干移動することが可能となり、落下の衝撃を吸収することが可能となる。 For this reason, even if the cartridge unit 10 is dropped from the stopper 22 side, the edge 17a, which is the rear end of the holder body 40, comes into contact with the ground, and damage due to dropping or the like can be reduced.
Further, as shown in FIG. 11, since the engagement opening 25 is formed larger in the front-rear direction than the claw 241, the claw 241 can move in the front-rear direction in the engagement opening 25. For this reason, even when the cartridge preparation 21 and the lid 53 are in contact with each other when dropped, the cartridge preparation 21 can move slightly in the longitudinal direction together with the stopper 22 and can absorb the impact of the drop. It becomes possible.
　また、図１１に示すように、ストッパ２２のピストン挿入開口部２３の径Ｒ１は、カートリッジ製剤２１のカートリッジ開口部２０の径Ｒ２と同等もしくは、カートリッジ開口部２０の径より小径としている。
　これにより、上述のように若干の隙間を設けた保持による結果として、カートリッジホルダ３０とカートリッジ製剤２１の軸心が合っていない状態が生じた場合でも、ストッパ２２のピストン挿入開口部２３を通過したピストン１４は確実にカートリッジ製剤２１のカートリッジ開口部２０へと導かれることになる。 Also, as shown in FIG. 11, the diameter R1 of the piston insertion opening 23 of the stopper 22 is equal to or smaller than the diameter R2 of the cartridge opening 20 of the cartridge preparation 21.
As a result, as a result of the holding with a slight gap as described above, even when the cartridge holder 30 and the cartridge preparation 21 are not aligned with each other, the piston insertion opening 23 of the stopper 22 passes. The piston 14 is surely guided to the cartridge opening 20 of the cartridge preparation 21.
　また、ストッパ２２を合成樹脂で形成すると共に、ストッパ２２はピストン１４よりも軟質に形成されている。これにより、ピストン１４がストッパ２２のピストン挿入開口部２３を通過する時に、仮に接触した時でもこのピストン１４が磨耗することを抑制することが出来る。
　また、本実施の形態では、上述のようにストッパ２２のピストン挿入開口部２３の外周縁には、図８から図１０に示すように、４本（複数）の係合爪２４が９０度の所定間隔で設けられている。これにより、ストッパ２２は、ホルダ本体４０のホルダ本体後端側開口部１７の内周に、バランスよく、且つ、強固に装着することが可能となる。 Further, the stopper 22 is formed of synthetic resin, and the stopper 22 is formed to be softer than the piston 14. Thereby, when the piston 14 passes through the piston insertion opening 23 of the stopper 22, it is possible to prevent the piston 14 from being worn even if it comes into contact.
In the present embodiment, as described above, four (plural) engaging claws 24 are 90 degrees on the outer peripheral edge of the piston insertion opening 23 of the stopper 22, as shown in FIGS. They are provided at predetermined intervals. As a result, the stopper 22 can be firmly and securely mounted on the inner periphery of the holder body rear end opening 17 of the holder body 40.
　また、係合爪２４の間には、当接爪２６が設けられており、この当接爪２６の内周部分には、カートリッジ製剤２１の外周面に向けて突出する突起２７が設けられている。このため、このストッパ２２によるカートリッジ製剤２１の後端側の支持がバランスよく、且つ、強固に支持することが可能となる。
　また本実施形態においては、ホルダ本体４０内にカートリッジ製剤２１が挿入され、続いてホルダ本体４０のホルダ本体後端側開口部１７から、ストッパ２２を挿入し、その係合爪２４を、ホルダ本体４０の係合開口部２５に係合させた状態、つまり図４の状態において、図５に示すラベル２８が、ホルダ本体４０の外周に等間隔で設けた４つの係合開口部２５を覆うように貼り付けられる。 Further, a contact claw 26 is provided between the engaging claws 24, and a protrusion 27 protruding toward the outer peripheral surface of the cartridge preparation 21 is provided on the inner peripheral portion of the contact claw 26. Yes. For this reason, the support of the rear end side of the cartridge preparation 21 by the stopper 22 can be firmly and well balanced.
In the present embodiment, the cartridge preparation 21 is inserted into the holder main body 40, and then the stopper 22 is inserted from the holder main body rear end side opening 17 of the holder main body 40, and the engaging claw 24 is connected to the holder main body 40. 4, the label 28 shown in FIG. 5 covers the four engagement openings 25 provided at equal intervals on the outer periphery of the holder body 40 in the state engaged with the 40 engagement openings 25, that is, in the state shown in FIG. Is pasted.
　このラベル２８は、カートリッジ製剤２１の種類や有効期限などを記載したものであり、このラベル２８を貼り付けることによって、上述した係合開口部２５を覆えば、ラベル２８を破損せずに係合開口部２５から係合爪２４を内側に押し込んで外すことが不可能となる。その結果として、カートリッジホルダ３０内からカートリッジ製剤２１を取り出したり、その後、別のカートリッジ製剤２１を挿入したりすることも防止できるものである。
　つまり、本実施形態におけるシリンジユニットは、カートリッジ製剤２１とホルダ本体４０が、ストッパ２２を利用して、一体化されているものであり、これは、図１に示す専用の薬剤注入装置にのみ装着することが可能となっている。 The label 28 describes the type and expiration date of the cartridge preparation 21. When the label 28 is applied to cover the engagement opening 25 described above, the label 28 can be engaged without being damaged. The engaging claw 24 cannot be pushed inward from the opening 25 and removed. As a result, it is also possible to prevent the cartridge preparation 21 from being taken out from the cartridge holder 30 and thereafter inserting another cartridge preparation 21.
That is, in the syringe unit in this embodiment, the cartridge preparation 21 and the holder main body 40 are integrated using the stopper 22, which is attached only to the dedicated drug injection device shown in FIG. 1. It is possible to do.
　＜特徴＞
　（１）
　本実施の形態のカートリッジホルダ３０は、図６に示すように、薬剤入りのカートリッジ製剤２１（カートリッジの一例）を保持し、薬剤注入装置に装着されるカートリッジホルダ３０であって、ホルダ本体４０と、ストッパ２２とを有する。ホルダ本体４０は、筒状であって、カートリッジ製剤２１が挿入されるホルダ本体後端側開口部１７（第１開口部の一例）と、側面に設けられた係合開口部２５（被係合部の一例）とを有する。ストッパ２２は、薬剤注入装置に設けられた薬剤注入用のピストン１４が挿入されるピストン挿入開口部２３（第２開口部の一例）と、ホルダ本体４０に装着するためにピストン挿入開口部２３（第２開口部の一例）の周囲から突出して形成され、係合開口部２５（被係合部の一例）と係合する係合爪２４とを有し、ホルダ本体４０にカートリッジ製剤２１を保持するためにホルダ本体４０のホルダ本体後端側開口部１７（第１開口部の一例）に装着される。 <Features>
(1)
As shown in FIG. 6, the cartridge holder 30 of the present embodiment is a cartridge holder 30 that holds a cartridge preparation 21 (an example of a cartridge) containing a drug and is attached to a drug injection device. And a stopper 22. The holder main body 40 has a cylindrical shape, and the holder main body rear end side opening 17 (an example of the first opening) into which the cartridge preparation 21 is inserted, and the engagement opening 25 provided on the side surface (engaged) Part). The stopper 22 includes a piston insertion opening 23 (an example of a second opening) into which a drug injection piston 14 provided in the drug injection device is inserted, and a piston insertion opening 23 ( An engaging claw 24 that projects from the periphery of the second opening (an example of the second opening) and engages with the engaging opening 25 (an example of the engaged part), and holds the cartridge preparation 21 in the holder body 40. For this purpose, the holder body 40 is attached to the holder body rear end side opening 17 (an example of the first opening).
　これにより、カートリッジ製剤２１は、カートリッジホルダ３０内に装着された状態で、カートリッジ製剤２１とカートリッジホルダ３０を一体として保管・携帯・薬剤注入装置への装着が行なうことが出来る。
　このため、保管・携帯・薬剤注入装置への装着時等に、誤って、それを落下させたとしても、カートリッジ製剤２１の損傷を防止することができる。 Thereby, the cartridge preparation 21 can be stored, carried, and attached to the medicine injection device as a unit with the cartridge preparation 21 and the cartridge holder 30 in a state of being mounted in the cartridge holder 30.
For this reason, even if it is accidentally dropped at the time of storage, carrying, or mounting on a medicine injection device, damage to the cartridge preparation 21 can be prevented.
　また、カートリッジ製剤２１とカートリッジホルダ３０を一体として取り扱うことが出来るため、操作性が良い。
　上記実施の形態の薬剤注入装置は、自動で薬剤を注入する装置であり、患者が利用する場合が多いが、薬剤の扱いに慣れない患者にとってもカートリッジ製剤をホルダごと取り扱うことができるため、より安全に容易に操作することが可能となる。 Further, since the cartridge preparation 21 and the cartridge holder 30 can be handled as a unit, operability is good.
The drug injection device of the above embodiment is a device for automatically injecting a drug and is often used by a patient. However, since a cartridge preparation can be handled together with a holder for a patient who is not used to handling a drug, It becomes possible to operate safely and easily.
　また、これにより、係合爪２４を係合開口部２５に係合するだけで、簡単にカートリッジ製剤２１をカートリッジホルダ３０に保持することが出来る。
　また、例えば、係合爪２４を内側に押し込むことにより、係合爪２４を係合開口部２５から離間させることが出来、カートリッジホルダ３０からカートリッジ製剤２１を取り出すことが可能である。 In addition, the cartridge preparation 21 can be easily held in the cartridge holder 30 simply by engaging the engagement claw 24 with the engagement opening 25.
Further, for example, by pushing the engaging claw 24 inward, the engaging claw 24 can be separated from the engaging opening 25, and the cartridge preparation 21 can be taken out from the cartridge holder 30.
　このため、使い切ったカートリッジ製剤２１を破棄したとしても、カートリッジホルダ３０を再利用することが出来るため、コストを低減することが出来るとともに、資源の再利用を図ることが出来る。
　また、ストッパ２２をカートリッジ製剤２１の後端部分に装着する際に、係合爪２４がガイドの役割をするため装着しやすい。 For this reason, even if the used cartridge preparation 21 is discarded, the cartridge holder 30 can be reused, so that costs can be reduced and resources can be reused.
Further, when the stopper 22 is attached to the rear end portion of the cartridge preparation 21, the engaging claw 24 serves as a guide and is easy to attach.
　（２）
　本実施の形態のカートリッジホルダ３０では、ホルダ本体４０は、接続部４２（ホルダ側接続部の一例）と、位置決め部１８を有している。接続部４２は、ホルダ本体後端側開口部１７（第１開口部の一例）の反対側に設けられ、注射針１２が接続される。位置決め部１８は、接続部４２の周囲に設けられ、接続部４２からホルダ本体後端側開口部１７に向かって径が広くなるようにテーパー形状に形成されている。位置決め部１８は、カートリッジ製剤２１の注射針１２が接続される接続部５２（カートリッジ側接続部の一例）の周囲に形成され、位置決め部１８に対応したテーパー形状を有する先端側当接部１９（外周面の一例）に当接することにより、カートリッジホルダ３０に対するカートリッジ製剤２１の位置決めを行う。
　これにより、カートリッジホルダ３０にカートリッジ製剤２１を挿入するだけで、位置決め部１８上を先端側当接部１９が滑り自動的に位置決めを行うことが出来るため、手間を掛けず簡易にカートリッジホルダ３０内におけるカートリッジ製剤２１の位置決めを行うことが出来る。 (2)
In the cartridge holder 30 of the present embodiment, the holder main body 40 includes a connection portion 42 (an example of a holder-side connection portion) and the positioning portion 18. The connection part 42 is provided on the opposite side of the holder body rear end side opening part 17 (an example of the first opening part), and the injection needle 12 is connected thereto. The positioning portion 18 is provided around the connection portion 42, and is formed in a tapered shape so that the diameter increases from the connection portion 42 toward the holder body rear end side opening portion 17. The positioning portion 18 is formed around a connection portion 52 (an example of a cartridge-side connection portion) to which the injection needle 12 of the cartridge preparation 21 is connected, and has a distal end side contact portion 19 (having a tapered shape corresponding to the positioning portion 18). The cartridge preparation 21 is positioned with respect to the cartridge holder 30 by abutting on an example of the outer peripheral surface.
As a result, the tip end side abutting portion 19 can slide automatically on the positioning portion 18 simply by inserting the cartridge preparation 21 into the cartridge holder 30, so that the inside of the cartridge holder 30 can be simply and easily saved. Positioning of the cartridge preparation 21 can be performed.
　（３）
　本実施の形態のカートリッジホルダ３０では、位置決め部１８は、カートリッジを保持する第１保持部と兼ねられており、第１保持部は、図１２（ａ）に示すように少なくとも一部分にカートリッジ製剤２１のテーパー形状を有する先端側当接部１９（外周面の一例）との間に隙間Ｓ１を有している。 (3)
In the cartridge holder 30 of the present embodiment, the positioning portion 18 also serves as a first holding portion that holds the cartridge, and the first holding portion is at least partially in the cartridge preparation 21 as shown in FIG. A clearance S1 is provided between the tip end side contact portion 19 (an example of the outer peripheral surface) having a tapered shape.
　これにより、隙間Ｓ１が形成された状態でカートリッジ製剤２１を保持することが出来るため、落下等によりカートリッジホルダ３０に加わる衝撃が直接的にカートリッジ製剤２１に加わることがなく、衝撃に対する強度の強いものとなる。この微少な隙間Ｓ１は薬剤を注入する際、ピストン１４がガスケット１５３を押す事で無くなり、カートリッジ製剤２１が長手方向に精度良く位置決めされる。 Thereby, since the cartridge preparation 21 can be held in a state where the gap S1 is formed, the impact applied to the cartridge holder 30 by dropping or the like is not directly applied to the cartridge preparation 21, and the strength against impact is strong. It becomes. The minute gap S1 disappears when the drug is injected, and the piston 14 presses the gasket 153, and the cartridge preparation 21 is accurately positioned in the longitudinal direction.
　（４）
　本実施の形態のカートリッジホルダ３０では、ストッパ２２は、カートリッジ製剤２１を保持するカートリッジ保持部５０（第２保持部の一例）を更に有する。カートリッジ保持部５０は、蓋部５３と、複数の当接爪２６（当接部の一例）を有している。蓋部５３は、ピストン挿入開口部２３（第２開口部の一例）が設けられており、ホルダ本体後端側開口部１７（第１開口部の一例）を塞ぐように配置される。複数の当接爪２６は、ホルダ本体４０に装着された状態において蓋部５３のピストン挿入開口部２３（第２開口部の一例）の周囲からホルダ本体後端側開口部１７（第１開口部）側に向かって突出するように形成されている。カートリッジ製剤２１は、複数の当接爪２６の間に挟まるように保持される。 (4)
In the cartridge holder 30 of the present embodiment, the stopper 22 further has a cartridge holding part 50 (an example of a second holding part) that holds the cartridge preparation 21. The cartridge holding part 50 includes a lid part 53 and a plurality of contact claws 26 (an example of a contact part). The lid 53 is provided with a piston insertion opening 23 (an example of a second opening) and is disposed so as to close the holder main body rear end side opening 17 (an example of a first opening). The plurality of contact claws 26 are attached to the holder main body 40 from the periphery of the piston insertion opening 23 (an example of the second opening) of the lid portion 53 from the holder main body rear end side opening 17 (first opening). ) To project toward the side. The cartridge preparation 21 is held so as to be sandwiched between the plurality of contact claws 26.
　このように、複数の当接爪により、カートリッジ製剤２１を保持することが出来る。また、蓋部５３がカートリッジ製剤２１の後端に当接することによりカートリッジ製剤２１を保持できる。
　このため、ホルダ本体４０にストッパ２２を挿入するだけで、カートリッジ製剤２１を保持することが出来る。
　また、ストッパ２２をカートリッジ製剤２１の後端部分に装着する際に、複数の当接爪２６がガイドの役割をするため装着しやすい。 Thus, the cartridge preparation 21 can be held by a plurality of contact claws. Further, the cartridge preparation 21 can be held by the lid portion 53 coming into contact with the rear end of the cartridge preparation 21.
For this reason, the cartridge preparation 21 can be held only by inserting the stopper 22 into the holder body 40.
In addition, when the stopper 22 is attached to the rear end portion of the cartridge preparation 21, the plurality of contact claws 26 serve as guides and are easy to attach.
　（５）
　本実施の形態のカートリッジホルダ３０では、複数の当接爪２６とカートリッジ製剤２１の間には、少なくとも一部に隙間が形成される。
　これにより、隙間が形成された状態でカートリッジ製剤２１を保持することが出来るため、落下等によりカートリッジホルダ３０に加わる衝撃が直接的にカートリッジ製剤２１に加わることがなく、衝撃に対する強度の強いものとなる。 (5)
In the cartridge holder 30 of the present embodiment, a gap is formed at least partially between the plurality of contact claws 26 and the cartridge preparation 21.
Thereby, since the cartridge preparation 21 can be held in a state where a gap is formed, the impact applied to the cartridge holder 30 due to dropping or the like is not directly applied to the cartridge preparation 21, and the strength against impact is strong. Become.
　（６）
　本実施の形態のカートリッジホルダ３０では、図１１に示すように、ストッパ２２のピストン挿入開口部２３（第２開口部の一例）の径Ｒ１は、カートリッジ製剤２１のピストン１４が挿入されるピストン挿入開口部２３（挿入部の一例）の径Ｒ２以下である。
　これにより、上述のように若干の隙間を設けた保持による結果として、カートリッジホルダ３０とカートリッジ製剤２１の軸心が合っていない状態が生じた場合でも、ストッパ２２のピストン挿入開口部２３を通過したピストン１４をより確実にカートリッジ製剤２１のカートリッジ開口部２０へと導くことが出来る。 (6)
In the cartridge holder 30 of the present embodiment, as shown in FIG. 11, the diameter R1 of the piston insertion opening 23 (an example of the second opening) of the stopper 22 is the piston insertion into which the piston 14 of the cartridge preparation 21 is inserted. It is below the diameter R2 of the opening part 23 (an example of an insertion part).
As a result, as a result of the holding with a slight gap as described above, even when the cartridge holder 30 and the cartridge preparation 21 are not aligned with each other, the piston insertion opening 23 of the stopper 22 passes. The piston 14 can be more reliably guided to the cartridge opening 20 of the cartridge preparation 21.
　（７）
　本実施の形態のカートリッジホルダ３０では、図１１に示すように、ストッパ２２は、ピストン挿入開口部２３（第２開口部の一例）の周縁２３ｅにＲ形状を有する。
　これにより、ピストン１４がストッパ２２のピストン挿入開口部２３をスムーズに通過することが出来る。 (7)
In the cartridge holder 30 of the present embodiment, as shown in FIG. 11, the stopper 22 has an R shape at the peripheral edge 23e of the piston insertion opening 23 (an example of the second opening).
Thereby, the piston 14 can pass smoothly through the piston insertion opening 23 of the stopper 22.
　（８）
　本実施の形態のカートリッジホルダ３０では、ストッパ２２は、合成樹脂によって形成されており、ピストン１４よりも軟質に形成されている。
　これにより、ピストン１４がストッパ２２のピストン挿入開口部２３を通過する時に、仮に接触した時でもこのピストン１４が磨耗することを抑制することが出来る。 (8)
In the cartridge holder 30 of the present embodiment, the stopper 22 is made of synthetic resin and is softer than the piston 14.
Thereby, when the piston 14 passes through the piston insertion opening 23 of the stopper 22, it is possible to prevent the piston 14 from being worn even if it comes into contact.
　（９）
　本実施の形態のカートリッジホルダ３０では、係合爪２４は、蓋部５３の外周に沿って所定間隔を空けて複数設けられている。
　これにより、ストッパ２２は、ホルダ本体４０のホルダ本体後端側開口部１７内周に、バランスよく、且つ、強固に装着することが可能となる。 (9)
In the cartridge holder 30 of the present embodiment, a plurality of engagement claws 24 are provided along the outer periphery of the lid portion 53 with a predetermined interval.
As a result, the stopper 22 can be firmly and securely mounted on the inner periphery of the holder body rear end side opening 17 of the holder body 40.
　（１０）
　本実施の形態のカートリッジホルダ３０では、係合爪２４は、蓋部５３の外周に沿って所定間隔を空けて複数設けられている。当接爪２６（当接部の一例）は、係合爪２４の間に配置されている。当接爪２６（当接部の一例）は、カートリッジ製剤２１の外周面側に向けて設けられた突起２７を有する。
　このように複数の突起２７によって保持することにより、ストッパ２２によるカートリッジ製剤２１の後端側の支持がバランスよく、且つ、強固に支持することが可能となる。 (10)
In the cartridge holder 30 of the present embodiment, a plurality of engagement claws 24 are provided along the outer periphery of the lid portion 53 with a predetermined interval. The contact claw 26 (an example of a contact portion) is disposed between the engagement claws 24. The contact claw 26 (an example of a contact portion) has a protrusion 27 provided toward the outer peripheral surface side of the cartridge preparation 21.
By holding the plurality of protrusions 27 in this manner, the support on the rear end side of the cartridge preparation 21 by the stopper 22 can be balanced and firmly supported.
　（１１）
　本実施の形態のカートリッジユニット１０は、カートリッジ製剤２１と、カートリッジ製剤２１が収納されたカートリッジホルダ３０を備えている。
　これにより、カートリッジ製剤２１は、カートリッジホルダ３０内に装着された状態で、保管・携帯・薬剤注入装置への装着が行なうことが出来る。
　このため、保管・携帯・薬剤注入装置への装着時等に、誤って、それを落下させたとしても、カートリッジ製剤２１の損傷を防止することができる。 (11)
The cartridge unit 10 of the present embodiment includes a cartridge preparation 21 and a cartridge holder 30 in which the cartridge preparation 21 is stored.
As a result, the cartridge preparation 21 can be attached to the storage / portable / pharmaceutical injection device in a state of being attached in the cartridge holder 30.
For this reason, even if it is accidentally dropped at the time of storage, carrying, or mounting on a medicine injection device, damage to the cartridge preparation 21 can be prevented.
　（１２）
　本実施の形態のカートリッジユニット１０は、カートリッジ製剤２１と、カートリッジ製剤２１が収納されたカートリッジホルダ３０と、ラベル２８とを備えている。係合開口部２５は、ホルダ本体４０の側面に形成された孔である。ラベル２８は、係合開口部２５を塞ぐようにカートリッジホルダ３０に貼り付けられる。
　これにより、ラベル２８を破損せずに係合開口部２５から係合爪２４を内側に押し込んで外すことが不可能となる。その結果として、カートリッジホルダ３０内からカートリッジ製剤２１を取り出したり、その後、別のカートリッジ製剤２１を挿入したりすることも防止できる。 (12)
The cartridge unit 10 according to the present embodiment includes a cartridge preparation 21, a cartridge holder 30 in which the cartridge preparation 21 is stored, and a label 28. The engagement opening 25 is a hole formed in the side surface of the holder main body 40. The label 28 is affixed to the cartridge holder 30 so as to close the engagement opening 25.
Thereby, it becomes impossible to push the engagement claw 24 inwardly from the engagement opening 25 without damaging the label 28. As a result, it is possible to prevent the cartridge preparation 21 from being taken out of the cartridge holder 30 and then inserting another cartridge preparation 21.
　（１３）
　本実施の形態の薬剤注入装置は、装着部１３と、ピストン１４とを備える。装着部１３は、カートリッジユニット１０が装着される。ピストン１４は、装着部１３に装着されるカートリッジユニット１０のカートリッジホルダ３０のピストン挿入開口部２３（第２開口部の一例）から、カートリッジ製剤２１のカートリッジ開口部２０（挿入部の一例）を介して、カートリッジ製剤２１内に挿入される。
　これにより、カートリッジ製剤２１は、カートリッジホルダ３０内に装着された状態で、薬剤注入装置への装着を行なうことが出来、薬剤注入も行うことが出来る。 (13)
The drug injection device according to the present embodiment includes a mounting portion 13 and a piston 14. The mounting unit 13 is mounted with the cartridge unit 10. The piston 14 passes from the piston insertion opening 23 (an example of the second opening) of the cartridge holder 30 of the cartridge unit 10 attached to the attachment part 13 via the cartridge opening 20 (an example of the insertion part) of the cartridge preparation 21. Is inserted into the cartridge preparation 21.
As a result, the cartridge preparation 21 can be attached to the medicine injecting device in a state where it is attached in the cartridge holder 30, and the medicine can be injected.
　＜他の実施の形態＞
　（Ａ）
　上記実施の形態では、図１１に示すように、ストッパ２２のピストン挿入開口部２３の周縁２３ｅは、ピストン１４の挿入方向側にＲ形状を有しているが、このような形状に限られるものではない。例えば、図１３に示すようなテーパー形状であってもよい。図１３に示すピストン挿入開口部２３１の縁２３１ｅは、後端（ピストン１４側）に向かうに従って径が大きくなるようにテーパー形状に形成されている。ピストン１４をガイドするテーパー形状を設ける事により、ピストン１４がストッパ２２のピストン挿入開口部２３を通過する際にスムーズに通過することが出来る。また、ストッパ２２をピストンよりも軟性とすることにより、ピストン１４を、更にスムーズにピストン挿入開口部２３を通過させることが出来る。 <Other embodiments>
(A)
In the above embodiment, as shown in FIG. 11, the peripheral edge 23e of the piston insertion opening 23 of the stopper 22 has an R shape on the insertion direction side of the piston 14, but is limited to such a shape. is not. For example, a tapered shape as shown in FIG. The edge 231e of the piston insertion opening 231 shown in FIG. 13 is formed in a tapered shape so that the diameter increases toward the rear end (piston 14 side). By providing the tapered shape for guiding the piston 14, the piston 14 can pass smoothly when passing through the piston insertion opening 23 of the stopper 22. Further, by making the stopper 22 softer than the piston, the piston 14 can pass through the piston insertion opening 23 more smoothly.
　（Ｂ）
　また、上記実施の形態では、ストッパ２２のピストン挿入開口部２３の径Ｒ１は、カートリッジ製剤２１のカートリッジ開口部２０の径Ｒ２と同等もしくはカートリッジ開口部２０よりも小径に形成されているが、ピストン１４の径をカートリッジ開口部２０よりも小径に形成しており、ピストン挿入開口部２３の径Ｒ１を、カートリッジ開口部２０の径Ｒ２よりも大きく形成してもよい。このような構成を、図１４に示す。 (B)
In the above-described embodiment, the diameter R1 of the piston insertion opening 23 of the stopper 22 is equal to or smaller than the diameter R2 of the cartridge opening 20 of the cartridge preparation 21. The diameter 14 may be smaller than the cartridge opening 20, and the diameter R 1 of the piston insertion opening 23 may be larger than the diameter R 2 of the cartridge opening 20. Such a configuration is shown in FIG.
　また、カートリッジホルダ３０内においてカートリッジ製剤２１ががたついたとしても、ピストン挿入開口部２３の縁がカートリッジ開口部２０に重ならないようにＲ１及びＲ２が設定されているほうがより好ましい。
　又、カートリッジ製剤２１の後端面２１ｓが、蓋部５３とオーバーラップしている。オーバーラップ部分がＷで示されている。 Further, even if the cartridge preparation 21 rattles in the cartridge holder 30, it is more preferable that R1 and R2 are set so that the edge of the piston insertion opening 23 does not overlap the cartridge opening 20.
Further, the rear end surface 21 s of the cartridge preparation 21 overlaps the lid portion 53. The overlap portion is indicated by W.
　又、図１４に示すように、係合爪２４の長さをＬ１とした場合、Ｌ１は組立て性を考慮し７ｍｍ～１５ｍｍの範囲の長さに設定されるほうが好ましい。また係合爪２４の厚さをＤ１とすると、組立て性と強度を考慮し、Ｄ１は０．５ｍｍ～１ｍｍの範囲の長さに設定されるほうが好ましい。
　また、ストッパ２２のピストン挿入開口部２３の寸法は、カートリッジ開口部２０よりも半径がＤ２大きい寸法に設定されているほうが好ましい。このＤ２は、０．２ｍｍ～０．５ｍｍの範囲内に設定されるほうが好ましい。
　また、係合爪２４の幅をＤ３とすると、Ｄ３は、組立て性と強度を考慮し、３ｍｍ～５ｍｍの範囲に設定されるほうが好ましい。 As shown in FIG. 14, when the length of the engaging claw 24 is L1, it is preferable that L1 is set to a length in the range of 7 mm to 15 mm in consideration of assemblability. When the thickness of the engaging claw 24 is D1, it is preferable to set D1 to a length in the range of 0.5 mm to 1 mm in consideration of assembling property and strength.
The dimension of the piston insertion opening 23 of the stopper 22 is preferably set to a dimension having a radius larger than the cartridge opening 20 by D2. This D2 is preferably set within a range of 0.2 mm to 0.5 mm.
Further, when the width of the engaging claw 24 is D3, it is preferable to set D3 in a range of 3 mm to 5 mm in consideration of assembling property and strength.
　（Ｃ）
　上記実施の形態では、図８に示すように、蓋部５３の外周に沿って４つの係合爪２４が設けられており、係合爪２４の間にそれぞれ当接爪２６が設けられている。すなわち、４つの係合爪２４が等間隔で設けられ、４つの当接爪２６が等間隔で設けられているが、このような構成に限らなくても良い。 (C)
In the above embodiment, as shown in FIG. 8, the four engaging claws 24 are provided along the outer periphery of the lid portion 53, and the abutting claws 26 are respectively provided between the engaging claws 24. . That is, the four engaging claws 24 are provided at equal intervals and the four contact claws 26 are provided at equal intervals. However, the configuration is not limited to this.
　（Ｃ－１）
　例えば、図１５に示すように、２つの係合爪２４が設けられたストッパ２２０が用いられても良い。図１５に示すストッパ２２０では、２つの係合爪２４は対向して配置されている。そして、２つの係合爪２４の間のそれぞれ（図１５において上側の間と下側の間）には、当接爪６６が設けられている。それぞれの当接爪６６には、中心軸２２０ａ方向に向けて突起２７が２つずつ設けられている。この突起２７は、上記実施の形態と同様に中心軸２２０ａ方向に沿って突状に形成されている。また、４つの突起２７は、上記実施の形態と同様に２つずつが対向するように配置されている。すなわち、４つの突起２７は、平面視において中心軸２２０ａを中心にして９０度間隔で形成されている。
　このような構成のストッパ２２０では、係合爪２４が２つしか設けられていないため、ホルダ本体４０への係合が容易で組立て性に優れている。
　尚、組立て性及び強度を考慮すると、係合爪２４の幅Ｄ３は、３ｍｍ～５ｍｍの間に設定されるほうが好ましい。 (C-1)
For example, as shown in FIG. 15, a stopper 220 provided with two engagement claws 24 may be used. In the stopper 220 shown in FIG. 15, the two engaging claws 24 are arranged to face each other. A contact claw 66 is provided between each of the two engagement claws 24 (between the upper side and the lower side in FIG. 15). Each contact claw 66 is provided with two projections 27 in the direction of the central axis 220a. The protrusion 27 is formed in a protruding shape along the direction of the central axis 220a as in the above embodiment. Further, the four protrusions 27 are arranged so that two each face each other as in the above embodiment. That is, the four protrusions 27 are formed at intervals of 90 degrees around the central axis 220a in plan view.
In the stopper 220 having such a configuration, since only two engagement claws 24 are provided, the engagement with the holder main body 40 is easy and the assembly is excellent.
In consideration of assemblability and strength, the width D3 of the engaging claw 24 is preferably set between 3 mm and 5 mm.
　（Ｃ－２）
　また、例えば図１６に示すように、３つの係合爪２４と３つの当接爪２６が設けられたストッパ２２１が用いられても良い。図１６に示すストッパ２２１では、３つの係合爪２４が蓋部５３の外周に沿って等間隔で配置されている。いいかえると、３つの係合爪２４は、平面視において中心軸２２１ａを中心にして１２０度間隔で設けられている。係合爪２４のそれぞれの間に当接爪２６が設けられている。 (C-2)
For example, as shown in FIG. 16, a stopper 221 provided with three engagement claws 24 and three contact claws 26 may be used. In the stopper 221 shown in FIG. 16, the three engaging claws 24 are arranged at equal intervals along the outer periphery of the lid portion 53. In other words, the three engaging claws 24 are provided at intervals of 120 degrees around the central axis 221a in plan view. A contact claw 26 is provided between the engagement claws 24.
　このような構成のストッパ２２１では、係合爪２４が３つであるため、係合爪２４が４つの場合よりも組立て性が良い。更に、係合爪２４が３つの構成は、係合爪２４が２つの構成と比較して係合爪２４の傾きが生じにくい。
　尚、係合爪２４の数及び当接爪２６の数は、図１０、図１５、図１６の数２～４つに限られるものではなく、５個以上であってもよい。 In the stopper 221 having such a configuration, since there are three engaging claws 24, the assemblability is better than in the case of four engaging claws 24. Furthermore, the configuration with three engagement claws 24 is less likely to cause the inclination of the engagement claws 24 than the configuration with two engagement claws 24.
The number of engagement claws 24 and the number of contact claws 26 are not limited to the numbers 2 to 4 in FIGS. 10, 15, and 16, and may be 5 or more.
　（Ｄ）
　また、上記実施の形態では、当接爪２６は内側に向かって突出した突起２７を有する構成であるが、このような構成に限られない。
　（Ｄ－１）
　例えば、図１７に示すような構成のストッパ２２２が用いられても良い。図１７に示すストッパ２２２では、実施の形態のストッパ２２と異なり、突起２７が設けられていない当接爪７６が設けられている。この当接爪７６は、平面視において幅方向の中央部分が最も内側に突出するように形成されている。この突出した中央部分７６ａがカートリッジ製剤２１に当接する。 (D)
Moreover, in the said embodiment, although the contact nail | claw 26 is the structure which has the processus | protrusion 27 which protruded toward the inner side, it is not restricted to such a structure.
(D-1)
For example, a stopper 222 configured as shown in FIG. 17 may be used. In the stopper 222 shown in FIG. 17, unlike the stopper 22 of the embodiment, a contact claw 76 that is not provided with the protrusion 27 is provided. The abutment claw 76 is formed such that the central portion in the width direction protrudes inwardly in plan view. The projecting central portion 76a contacts the cartridge preparation 21.
　（Ｄ－２）
　また、例えば、図１８に示すような構成のストッパ２２３が用いられても良い。図１８に示すストッパ２２３の当接爪８６では、図１７に示すストッパ２２２の当接爪７６と異なり、中央部分７６ａが形成されておらず内側に平面８６ａが形成されている。この平面８６ａがカートリッジ製剤２１の外側面に当接する。 (D-2)
Further, for example, a stopper 223 configured as shown in FIG. 18 may be used. The contact claw 86 of the stopper 223 shown in FIG. 18 is different from the contact claw 76 of the stopper 222 shown in FIG. 17 in that the central portion 76a is not formed and a flat surface 86a is formed inside. The flat surface 86 a comes into contact with the outer surface of the cartridge preparation 21.
　このように、図１７の当接爪７６のように突起の形状を含めて、その内側を三角形状に形成したり、図１８の当接爪８６のように平面形状にすることによって、突出した突起２７を設けるよりも強度を向上することが出来る。また、強度が向上するため、当接爪７６、８６の軸方向（前後方向の長さ）の長さを長くすることが可能となり、寸法の自由度を増すことが出来る。また、図１７及び図１８に示す当接爪の場合、実施の形態の当接爪２６よりも形状を簡素化することが出来るため、加工が容易となり、コストを低減することが可能となる。 As described above, the protrusion includes the shape of the protrusion as in the contact claw 76 in FIG. 17, and the inner side thereof is formed in a triangular shape, or is formed in a planar shape as in the contact claw 86 in FIG. The strength can be improved as compared with the case where the protrusion 27 is provided. Further, since the strength is improved, the length of the contact claws 76 and 86 in the axial direction (length in the front-rear direction) can be increased, and the degree of dimensional freedom can be increased. Further, in the case of the contact claw shown in FIGS. 17 and 18, since the shape can be simplified as compared with the contact claw 26 of the embodiment, the processing becomes easy and the cost can be reduced.
　（Ｅ）
　また、上記実施の形態では、係合爪２４と当接爪２６の間には空間が形成されているが、係合爪２４と当接爪２６の間が接続されていても良い。
　図１９（ａ）は、係合爪２４と当接爪２６が接続された構成のカートリッジホルダのストッパ１００の平面図である。図１９（ｂ）は、図１９（ａ）のＤＤ´間断面矢視図である。図１９（ａ）及び図１９（ｂ）に示すように、ストッパ１００では、実施の形態のストッパ２２と異なり、係合爪２４と当接爪２６の間が繋がっており１つの円筒部１０１が形成されている。 (E)
Moreover, in the said embodiment, although the space is formed between the engaging claw 24 and the contact claw 26, between the engagement claw 24 and the contact claw 26 may be connected.
FIG. 19A is a plan view of the stopper 100 of the cartridge holder in which the engaging claw 24 and the contact claw 26 are connected. FIG. 19B is a cross-sectional view taken along the DD ′ line in FIG. As shown in FIGS. 19A and 19B, in the stopper 100, unlike the stopper 22 of the embodiment, the engagement claw 24 and the contact claw 26 are connected, and one cylindrical portion 101 is formed. Is formed.
　詳しく説明すると、ストッパ１００は、係合支持部２４０の一部（爪部２４１が設けられている部分よりも下側の部分）と、当接爪２６の突起２７を除く部分を繋ぐように連結部１０２が形成されており、この係合支持部２４０の一部と、当接爪２６の当接支持部２６０と、連結部１０２によって円筒部１０１が形成されている。
　このように図１９に示す構成では、蓋部５３の外周に沿って、係合爪２４と当接爪２６（当接部の一例）を繋ぐ連結部１０２が設けられている。 More specifically, the stopper 100 is connected so as to connect a part of the engagement support part 240 (a part below the part where the claw part 241 is provided) and a part excluding the protrusion 27 of the contact claw 26. A portion 102 is formed, and a cylindrical portion 101 is formed by a part of the engagement support portion 240, the contact support portion 260 of the contact claw 26, and the connecting portion 102.
As described above, in the configuration illustrated in FIG. 19, the connecting portion 102 that connects the engaging claw 24 and the contact claw 26 (an example of the contact portion) is provided along the outer periphery of the lid portion 53.
　これにより、円筒部１０１を設け、円筒部１０１の一部を当接爪２６の一部として利用し、一部を係合爪２４の一部として利用している。このように係合爪２４を蓋部５３から一定の高さまで当接爪２６と一体で形成することにより、強度を向上させることが可能となる。
　尚、蓋部５３から係合支持部２４０の先端までの長さをＬ１とし、円筒部１０１の蓋部５３からの長さをＬ２とし、Ｌ１とＬ２の差を３ｍｍ～１０ｍｍとする方が好ましい。このように設定することで、係合爪２４の先端が撓みやすく、また強度も確保することが出来る。 Thereby, the cylindrical part 101 is provided, a part of the cylindrical part 101 is used as a part of the contact claw 26, and a part is used as a part of the engaging claw 24. In this way, by forming the engaging claw 24 integrally with the abutting claw 26 from the lid portion 53 to a certain height, the strength can be improved.
It is preferable that the length from the lid portion 53 to the tip of the engagement support portion 240 is L1, the length from the lid portion 53 of the cylindrical portion 101 is L2, and the difference between L1 and L2 is 3 mm to 10 mm. . By setting in this way, the tip of the engaging claw 24 can be easily bent and the strength can be secured.
　（Ｆ）
　また、上記実施の形態では、当接爪２６が係合爪２４の間に設けられているが、これに限られるものではなく、当接爪２６の一部が係合爪２４の一部と兼ねられていても良い。
　図２０（ａ）は、係止爪の一部と当接爪の一部が兼ねられた構成のストッパ１１０の平面図である。図２０（ｂ）は、図２０（ａ）のＥＥ´間断面矢視図である。図２０（ａ）及び図２０（ｂ）に示すストッパ１１０では、４つの係合爪２４が設けられており、それぞれの係合爪２４の係合支持部２４０の内側に係合支持部２４０に沿って突起２７が形成されている。尚、突起２７は、係合支持部２４０の爪部２４１が形成されている先端部分までは形成されていない。すなわち、上記実施の形態における当接爪２６の当接支持部２６０が、係合爪２４の係合支持部２４０と兼ねられている。 (F)
In the above-described embodiment, the contact claw 26 is provided between the engagement claws 24. However, the present invention is not limited to this, and a part of the contact claw 26 is a part of the engagement claw 24. You may also be served.
FIG. 20A is a plan view of the stopper 110 having a configuration in which a part of the locking claw and a part of the abutment claw are combined. FIG. 20B is a cross-sectional view taken along the line EE ′ in FIG. In the stopper 110 shown in FIGS. 20A and 20B, four engagement claws 24 are provided, and the engagement support portions 240 are provided inside the engagement support portions 240 of the respective engagement claws 24. A protrusion 27 is formed along the line. The protrusion 27 is not formed up to the tip portion where the claw portion 241 of the engagement support portion 240 is formed. That is, the contact support portion 260 of the contact claw 26 in the above embodiment also serves as the engagement support portion 240 of the engagement claw 24.
　以上のように、図２０に示す構成では、係合爪２４は、蓋部５３の外周に沿って所定間隔を空けて４つ設けられており、係合支持部２４０と、爪部２４１を有している。係合支持部２４０は、蓋部５３から突出して形成されている。爪部２４１は、係合支持部２４０の先端に設けられ、係合開口部２５に係合される。当接爪２６は、当接支持部２６０と、突起２７を有している。当接支持部２６０は、蓋部５３から突出して形成されている。突起２７は、当接支持部２６０から内側に向かって形成されている。当接支持部２６０は、係合支持部２４０と兼ねられている。 As described above, in the configuration shown in FIG. 20, the four engaging claws 24 are provided along the outer periphery of the lid portion 53 at a predetermined interval, and have the engaging support portion 240 and the claw portion 241. is doing. The engagement support portion 240 is formed so as to protrude from the lid portion 53. The claw portion 241 is provided at the tip of the engagement support portion 240 and is engaged with the engagement opening portion 25. The contact claw 26 has a contact support portion 260 and a protrusion 27. The contact support portion 260 is formed so as to protrude from the lid portion 53. The protrusion 27 is formed inward from the contact support portion 260. The contact support portion 260 is also used as the engagement support portion 240.
　このように、係合爪２４の一部と当接爪２６の一部が兼ねられて一体で形成することにより、形状を簡素化することが出来、容易に製造することが可能となる。
　尚、蓋部５３から係合支持部２４０の先端までの長さをＬ１とし、突起２７の長さをＬ２とすると、Ｌ１とＬ２の差を３ｍｍ～１０ｍｍとする方が好ましい。このように設定することで、係合爪２４の先端が撓みやすく、また強度も確保することが出来る。
　又、上記図１５～２０で説明した複数の当接爪とカートリッジ製剤２１の間にも少なくとも一部に隙間が形成されているほうがより好ましい。 In this way, by forming a part of the engaging claw 24 and a part of the abutting claw 26 so as to be formed integrally, the shape can be simplified and manufacturing can be easily performed.
If the length from the lid 53 to the tip of the engagement support 240 is L1, and the length of the protrusion 27 is L2, the difference between L1 and L2 is preferably 3 mm to 10 mm. By setting in this way, the tip of the engaging claw 24 can be easily bent and the strength can be secured.
Further, it is more preferable that a gap is formed at least partially between the plurality of contact claws described in FIGS.
　（Ｇ）
　また、上記実施の形態では、係合爪２４は、ホルダ本体４０の内側に挿入されるように構成されているが、外側からホルダ本体４０に係合しても良い。 (G)
Moreover, in the said embodiment, although the engaging claw 24 is comprised so that it may be inserted inside the holder main body 40, you may engage with the holder main body 40 from the outer side.
　本発明のカートリッジホルダ、カートリッジホルダユニットは、落下等によるカートリッジ製剤の損傷を低減することが可能な効果を有し、薬剤注入装置としての活用が期待されるものである。 The cartridge holder and the cartridge holder unit of the present invention have an effect capable of reducing damage to the cartridge preparation due to dropping or the like, and are expected to be used as a medicine injection device.
　１　本体ケース
　２　表示部
　３　エアー抜きボタン
　４　完了ボタン
　５　電源ボタン
　６　薬剤注入ボタン
　７　先端キャップ
　８　確認窓
　９　開口部
　１０　カートリッジユニット
　１１　針キャップ
　１２　注射針
　１３　装着部
　１４　ピストン
　１５　モータ
　１６　ホルダ本体先端側開口部
　１７　ホルダ本体後端側開口部（第１開口部の一例）
　１８　位置決め部（位置決め部、第１保持部の一例）
　１９　先端側当接部（カートリッジのテーパー形状を有する外周面の一例）
　２０　カートリッジ開口部（挿入部の一例）
　２１　カートリッジ製剤（カートリッジの一例）
　２２　ストッパ
　２３　ピストン挿入開口部（第２開口部の一例）
　２４　係合爪
　２５　係合開口部（被係合部の一例）
　２６　当接爪（当接部の一例）
　２７　突起
　２８　ラベル
　２９　ピストン固定部
　３０　カートリッジホルダ
　４０　ホルダ本体
　４１　円筒部
　４２　接続部（ホルダ側接続部の一例）
　５０　カートリッジ保持部（第２保持部の一例）
　５１　円筒部
　５２　接続部（カートリッジ側接続部の一例）
　５３　蓋部
　６６、７６、８６　当接爪（当接部の一例）
　１００　ストッパ
　１０１　円筒部
　１０２　連結部
　１１０、２２０、２２１　ストッパ
　２４０　係合支持部
　２４１　爪部
　２６０　当接支持部
　２６１　突起 DESCRIPTION OF SYMBOLS 1 Main body case 2 Display part 3 Air release button 4 Complete button 5 Power button 6 Drug injection button 7 Tip cap 8 Confirmation window 9 Opening part 10 Cartridge unit 11 Needle cap 12 Injection needle 13 Mounting part 14 Piston 15 Motor 16 Holder main body side Opening part 17 Holder body rear end side opening part (example of first opening part)
18 Positioning part (an example of a positioning part and a first holding part)
19 Tip side contact portion (an example of an outer peripheral surface having a taper shape of a cartridge)
20 Cartridge opening (an example of an insertion part)
21 Cartridge formulation (example of cartridge)
22 Stopper 23 Piston insertion opening (example of second opening)
24 engaging claw 25 engaging opening (an example of engaged portion)
26 Contact claw (an example of a contact part)
27 Protrusion 28 Label 29 Piston fixing part 30 Cartridge holder 40 Holder body 41 Cylindrical part 42 Connection part (an example of a holder side connection part)
50 Cartridge holding part (an example of a second holding part)
51 Cylindrical part 52 Connection part (an example of cartridge side connection part)
53 Lid part 66, 76, 86 Contact claw (an example of a contact part)
DESCRIPTION OF SYMBOLS 100 Stopper 101 Cylindrical part 102 Connection part 110,220,221 Stopper 240 Engagement support part 241 Claw part 260 Contact support part 261 Protrusion

Claims (15)

  1. 　薬剤入りのカートリッジを保持し、薬剤注入装置に装着されるカートリッジホルダであって、
    　前記カートリッジが挿入される第１開口部と、側面に設けられた被係合部とを有する筒状のホルダ本体と、
    　前記薬剤注入装置に設けられている薬剤注入用のピストンが挿入される第２開口部と、前記ホルダ本体に装着するために前記第２開口部の周囲から突出して形成され、前記被係合部と係合する係合爪とを有し、前記ホルダ本体に前記カートリッジを保持するために前記ホルダ本体の前記第１開口部に装着されるストッパと、
    を備えたカートリッジホルダ。     A cartridge holder that holds a cartridge containing a medicine and is attached to a medicine injection device,
    A cylindrical holder body having a first opening into which the cartridge is inserted and an engaged portion provided on a side surface;
    A second opening into which a drug injection piston provided in the drug injection device is inserted; and a portion projecting from the periphery of the second opening to be attached to the holder body; A stopper fitted to the first opening of the holder body to hold the cartridge in the holder body;
    Cartridge holder with
  2. 　前記ホルダ本体は、
    　前記第１開口部の反対側に設けられ、注射針が接続されるホルダ側接続部と、
    　前記ホルダ側接続部の周囲に設けられ、前記ホルダ側接続部から前記第１開口部側に向かって径が広くなるようにテーパー形状に形成された位置決め部とを有し、
    　前記位置決め部は、
    　前記カートリッジの前記注射針が接続されるカートリッジ側接続部の周囲に形成され、前記位置決め部に対応したテーパー形状を有する外周面に当接することにより、前記カートリッジホルダに対する前記カートリッジの位置決めを行う、
    請求項１に記載のカートリッジホルダ。     The holder body is
    A holder-side connection portion provided on the opposite side of the first opening, to which an injection needle is connected;
    A positioning portion provided around the holder-side connection portion and formed in a tapered shape so that the diameter increases from the holder-side connection portion toward the first opening,
    The positioning part is
    The cartridge is positioned with respect to the cartridge holder by abutting an outer peripheral surface having a tapered shape corresponding to the positioning portion, which is formed around a cartridge side connection portion to which the injection needle of the cartridge is connected.
    The cartridge holder according to claim 1.
  3. 　前記位置決め部は、前記カートリッジを保持する第１保持部と兼ねられており、
    　前記第１保持部は、少なくとも一部分に前記カートリッジの前記テーパー形状を有する外周面との間に隙間を有している、
    請求項２記載のカートリッジホルダ。     The positioning portion is also used as a first holding portion for holding the cartridge,
    The first holding portion has a gap between at least a part of the outer peripheral surface having the tapered shape of the cartridge,
    The cartridge holder according to claim 2.
  4. 　前記ストッパは、前記カートリッジを保持する第２保持部を更に有し、
    　前記第２保持部は、
    　前記第２開口部が設けられており、前記第１開口部を塞ぐように配置される蓋部と、
    　前記ホルダ本体に装着された状態において前記蓋部の前記第２開口部の周囲から前記第１開口部側に向かって突出するように形成された複数の当接部を有し、
    　前記カートリッジは、前記複数の当接部に挟まれるように配置されて保持される、
    請求項１記載のカートリッジホルダ。     The stopper further includes a second holding portion for holding the cartridge,
    The second holding part is
    The second opening is provided, and a lid arranged to close the first opening;
    A plurality of contact portions formed so as to protrude from the periphery of the second opening portion of the lid portion toward the first opening portion in a state of being mounted on the holder body;
    The cartridge is disposed and held so as to be sandwiched between the plurality of contact portions.
    The cartridge holder according to claim 1.
  5. 　前記複数の当接部と前記カートリッジの間には、少なくとも一部に隙間が形成される、
    請求項４記載のカートリッジホルダ。     A gap is formed at least in part between the plurality of contact portions and the cartridge.
    The cartridge holder according to claim 4.
  6. 　前記ストッパの前記第２開口部の径は、前記カートリッジの前記ピストンが挿入される挿入部の径以下である、
    請求項１に記載のカートリッジホルダ。     The diameter of the second opening of the stopper is equal to or less than the diameter of the insertion portion into which the piston of the cartridge is inserted.
    The cartridge holder according to claim 1.
  7. 　前記ストッパは、
    　前記第２開口部の周縁にテーパー形状もしくはＲ形状を有する、
    請求項１に記載のカートリッジホルダ。     The stopper is
    Having a tapered shape or an R shape at the periphery of the second opening;
    The cartridge holder according to claim 1.
  8. 　前記ストッパは、合成樹脂によって形成されており、前記ピストンよりも軟質に形成されている、
    請求項１に記載のカートリッジホルダ。     The stopper is made of synthetic resin and is made softer than the piston.
    The cartridge holder according to claim 1.
  9. 　前記係合爪は、前記蓋部の外周に沿って所定間隔を空けて複数設けられている、請求項１に記載のカートリッジホルダ。 The cartridge holder according to claim 1, wherein a plurality of the engaging claws are provided at predetermined intervals along the outer periphery of the lid portion.
  10. 　前記係合爪は、前記蓋部の外周に沿って所定間隔を空けて複数設けられており、
    　前記当接部は、前記係合爪の間に配置されており、
    　前記当接部は、内側に向かって形成された突起を有する、
    請求項４記載のカートリッジホルダ。     A plurality of the engaging claws are provided at predetermined intervals along the outer periphery of the lid portion,
    The contact portion is disposed between the engagement claws,
    The contact portion has a protrusion formed inward.
    The cartridge holder according to claim 4.
  11. 　前記蓋部の外周に沿って、前記係合爪と前記当接部を繋ぐ連結部が設けられている、
    　請求項１０記載のカートリッジホルダ。     A connecting portion that connects the engaging claw and the abutting portion is provided along the outer periphery of the lid portion.
    The cartridge holder according to claim 10.
  12. 　前記係合爪は、
    　前記蓋部の外周に沿って所定間隔を空けて複数設けられており、
    　前記蓋部から突出して形成された係合支持部と、
    　前記係合支持部の先端に設けられ、前記被係合部に係合される爪部を有し、
    　前記当接部は、
    　前記蓋部から突出して形成された当接支持部と、
    　前記当接支持部から内側に向かって形成された突起を有し、
    　前記当接支持部は、前記係合支持部と兼ねられている、請求項４記載のカートリッジホルダ。     The engaging claw is
    A plurality are provided at predetermined intervals along the outer periphery of the lid,
    An engagement support formed to protrude from the lid,
    A claw portion provided at a tip of the engagement support portion and engaged with the engaged portion;
    The contact portion is
    An abutment support portion formed to protrude from the lid portion;
    A protrusion formed inward from the contact support portion;
    The cartridge holder according to claim 4, wherein the contact support portion also serves as the engagement support portion.
  13. 　薬剤入りのカートリッジと、
    　前記カートリッジが収納された、請求項１～１２のいずれかに記載のカートリッジホルダと、
    を備えたカートリッジユニット。     A cartridge containing medicine,
    The cartridge holder according to any one of claims 1 to 12, wherein the cartridge is stored;
    Cartridge unit with
  14. 　前記カートリッジホルダに貼り付けられたラベルを備え、
    　前記被係合部は、前記ホルダ本体の側面に形成された孔であり、
    　前記ラベルは、前記孔を塞ぐように貼り付けられる、
    請求項１３記載のカートリッジユニット。     Comprising a label affixed to the cartridge holder;
    The engaged portion is a hole formed in a side surface of the holder body,
    The label is attached so as to close the hole,
    The cartridge unit according to claim 13.
  15. 　請求項１３又は１４記載のカートリッジユニットが装着される装着部と、
    　前記装着部に装着される前記カートリッジユニットの前記カートリッジホルダの前記第２開口部から、前記カートリッジの挿入部を介して、前記カートリッジ内に挿入されるピストンと、
    を備えた薬剤注入装置。     A mounting portion to which the cartridge unit according to claim 13 or 14 is mounted;
    A piston that is inserted into the cartridge from the second opening of the cartridge holder of the cartridge unit that is mounted on the mounting portion, via the insertion portion of the cartridge;
    A drug infusion device comprising:
PCT/JP2013/004453 2012-09-25 2013-07-22 Cartridge holder, cartridge unit, and drug injection device to which cartridge unit is mounted WO2014049924A1 (en)

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JP2012210824A JP2015226555A (en) 2012-09-25 2012-09-25 Syringe unit and medicine injection device mounted with the same
JP2012-210824 2012-09-25

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