WO2014045323A1 - Pompe médicale - Google Patents

Pompe médicale Download PDF

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Publication number
WO2014045323A1
WO2014045323A1 PCT/JP2012/006036 JP2012006036W WO2014045323A1 WO 2014045323 A1 WO2014045323 A1 WO 2014045323A1 JP 2012006036 W JP2012006036 W JP 2012006036W WO 2014045323 A1 WO2014045323 A1 WO 2014045323A1
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WO
WIPO (PCT)
Prior art keywords
control unit
main control
sub
unit
display
Prior art date
Application number
PCT/JP2012/006036
Other languages
English (en)
Japanese (ja)
Inventor
朋子 上村
Original Assignee
テルモ株式会社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by テルモ株式会社 filed Critical テルモ株式会社
Priority to PCT/JP2012/006036 priority Critical patent/WO2014045323A1/fr
Publication of WO2014045323A1 publication Critical patent/WO2014045323A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/142—Pressure infusion, e.g. using pumps
    • A61M5/14212—Pumping with an aspiration and an expulsion action
    • A61M5/14228—Pumping with an aspiration and an expulsion action with linear peristaltic action, i.e. comprising at least three pressurising members or a helical member
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M2005/16863—Occlusion detection
    • A61M2005/16868—Downstream occlusion sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
    • A61M5/168—Means for controlling media flow to the body or for metering media to the body, e.g. drip meters, counters ; Monitoring media flow to the body
    • A61M5/16831—Monitoring, detecting, signalling or eliminating infusion flow anomalies
    • A61M2005/16863—Occlusion detection
    • A61M2005/16872—Upstream occlusion sensors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/18—General characteristics of the apparatus with alarm
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/33—Controlling, regulating or measuring
    • A61M2205/3368—Temperature
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/50—General characteristics of the apparatus with microprocessors or computers
    • A61M2205/502—User interfaces, e.g. screens or keyboards
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/36—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests with means for eliminating or preventing injection or infusion of air into body
    • A61M5/365—Air detectors

Definitions

  • the present invention relates to a medical pump for delivering a medicine to a patient.
  • an infusion pump is used, for example, in an intensive care unit (ICU) or the like, and is used to perform a liquid feeding treatment for a patient for a long time with high accuracy.
  • a predetermined drug bag (infusion bag) is arranged on the infusion pump, and an infusion tube lowered from the drug bag is sandwiched between the main body and the door, and the infusion tube is accommodated in the main body.
  • the door is held by closing the door.
  • the outer peripheral surface of the infusion tube set at a fixed position is sandwiched between a plurality of fingers in the main body and the inner surface of the door.
  • This infusion pump is a peristaltic infusion pump that feeds a drug by sequentially pressing a plurality of fingers along the length of the outer peripheral surface of the infusion tube (see Patent Document 1).
  • the infusion tube is held vertically through the infusion pump main body from top to bottom.
  • an infusion pump that holds an infusion tube in a horizontal direction in the body of the infusion pump has been proposed.
  • the infusion pump has a structure in which the infusion tube is held in the horizontal direction in the main body of the infusion pump so that the infusion tube passes vertically through the main body of the infusion pump from top to bottom. This is because the infusion tube does not get in the way even if a plurality of infusion pumps are stacked and held in a stacked state in the vertical position.
  • the upstream side of the infusion tube is disposed on the right side of the infusion pump main body, and the downstream side of the infusion tube is disposed on the left side of the infusion pump main body.
  • the drug is directed from the upstream side to the downstream side.
  • Liquid can be fed along a predetermined liquid feeding direction, and liquid can be fed correctly to the patient.
  • the medical pump of the present invention is a medical pump for delivering a medicine to a patient by pressing an infusion tube with a plurality of fingers, and is formed by a main control unit and circuit elements different from the main control unit. And a sub-control unit for controlling a controlled unit that is electrically connected to a motor for feeding the medicine and a display unit for displaying various types of information and is not directly controlled by the main control unit
  • the main control unit and the sub-control unit are medical pumps configured to monitor each other for abnormal operation. According to the said structure, each role of a main control part and a sub-control part can be divided
  • the sub control unit when the sub control unit detects an operation abnormality of the main control unit, the sub control unit controls and stops the operation of the motor so that the finger is in a predetermined position, and the main control unit When detecting an abnormal operation of the sub-control unit, the main control unit controls and stops the operation of the motor so that the finger is in a predetermined position.
  • the main control unit controls and stops the operation of the motor so that the finger is in a predetermined position.
  • a white screen is displayed on the display unit to display the operation abnormality of the main control unit, and the main control unit displays the sub control.
  • a white screen is displayed on the display unit to display the operation abnormality of the sub-control unit.
  • a buzzer for notifying the alarm is provided, and the buzzer notifies the alarm when the sub control unit detects an operation abnormality of the main control unit, and the main control unit operates the sub control unit.
  • the alarm is notified.
  • a battery monitoring unit that monitors a charging voltage abnormality of the battery is provided, and the temperature sensor is arranged in the battery monitoring unit.
  • the temperature sensor used in the said battery monitoring part is used, since it is not necessary to mount a temperature sensor as another component, reduction of a number of parts can be aimed at.
  • the display unit and an operation panel unit having operation buttons are arranged on an upper part of the main body of the medical pump, and a lower part of the main body of the medical pump is used for feeding the medicine. It is a region where a liquid feeding member is arranged.
  • the medical worker can perform the liquid feeding operation
  • the present invention can provide a medical pump that can ensure safety when a medical pump such as an infusion pump delivers a drug to a patient and can reduce costs.
  • FIG. 1 is a perspective view showing an infusion pump which is a preferred embodiment of the medical pump of the present invention.
  • FIG. 2 is a view of the infusion pump shown in FIG. 1 as viewed from the W direction.
  • the infusion pump 1 shown in FIGS. 1 and 2 is an example of a medical pump.
  • the infusion pump 1 is used, for example, in an intensive care unit (ICU, CCU, NICU) or the like, and for a patient, for example, an anticancer agent, an anesthetic agent, a chemotherapeutic agent, a blood transfusion, etc.
  • This is a micro continuous infusion pump used for performing microinjection treatment (also referred to as)) for a relatively long time with high accuracy.
  • This infusion pump 1 is used, for example, for selecting a drug to be used from a drug library and feeding the selected drug.
  • This drug library is drug information which is a drug administration setting group including drug names registered in advance in the drug library database (DB). By using this drug library, a medical worker does not have to perform complicated administration settings each time, and can select a drug and set a drug.
  • DB drug library database
  • the infusion pump 1 can accurately deliver liquid to the patient P from the medicine bag 170 filled with the medicine 171 via the clamp 179, the infusion tube 200, and the indwelling needle 172.
  • the drug is also called an infusion.
  • An infusion tube is also called an infusion line.
  • the infusion pump 1 has a main body cover 2 and a handle 2T, and the handle 2T can be extended in the N direction or stored in the T direction.
  • the main body cover 2 is also called a main body, and is integrally formed of a molded resin material having chemical resistance, and can be prevented from entering the infusion pump 1 even if a drug or the like is applied. have.
  • the main body cover 2 has the drip-proof treatment structure because the medicine 171 in the medicine bag 170 disposed above spills out or disinfects the disinfecting liquid used in the vicinity. Because there is.
  • a display unit 3 and an operation panel unit 4 are arranged on the upper portion 2 ⁇ / b> A of the main body cover 2.
  • the display unit 3 is an image display device, and uses, for example, a color liquid crystal display device. This display unit 3 can display not only information notation in Japanese but also information in a plurality of foreign languages as required.
  • the display unit 3 is disposed on the upper left side of the upper portion 2 ⁇ / b> A of the main body cover 2 and above the opening / closing cover 5.
  • the upper portion 2 ⁇ / b> A of the main body cover 2 is an upper half portion of the main body cover 2.
  • the lower part 2 ⁇ / b> B of the main body cover 2 is a lower half part of the main body cover 2.
  • a display portion 3 for displaying information and an operation panel portion 4 having a plurality of operation buttons are arranged on the upper portion 2A of the body cover 2 of the infusion pump 1, and a lower portion 2B of the body cover 2 of the infusion pump 1 is This is a region where an infusion tube 200 which is a liquid feeding member for feeding a medicine is arranged.
  • the medical worker can perform the liquid feeding operation of the medicine by the infusion pump 1 while confirming the information on the display unit 3 of the upper portion 2A of the main body cover 2.
  • the medical staff can operate the operation buttons on the operation panel unit 4 while checking the information on the display unit 3 of the upper portion 2A of the main body cover 2. For this reason, the operability of the infusion pump 1 is good.
  • the display unit 3 includes a display column 3B for a scheduled dose (mL) of drug administration, a display column 3C for an accumulated dose (mL) of drug administration, a display column 3D for a charge history, and a flow rate (mL / h).
  • a display column 3B for a scheduled dose (mL) of drug administration
  • a display column 3C for an accumulated dose (mL) of drug administration
  • a display column 3D for a charge history
  • a flow rate mL / h
  • the display unit 3 can also display a warning message.
  • the display unit 3 can change the display from, for example, a yellow display screen to a white display screen by turning on a backlight of an LED (light emitting diode).
  • the operation panel unit 4 is disposed on the right side of the display unit 3 in the upper part 2A of the main body cover 2, and the operation panel unit 4 includes, for example, a pilot lamp 4A, a fast-forward switch button 4B, and a start button as illustrated in FIG.
  • a switch button 4C, a stop switch button 4D, a menu selection button 4E, a power switch 4F, and the like are arranged.
  • an opening / closing cover 5 as a lid member is provided on the lower portion 2B of the main body cover 2 so as to be openable and closable in the R direction around the rotation shaft 5A.
  • the open / close cover 5 is a plate-like lid member that is formed long along the X direction.
  • the tube mounting part 50 and the liquid feeding drive part 60 are disposed inside the opening / closing cover 5.
  • An infusion tube 200 made of a flexible thermoplastic resin such as soft vinyl chloride is set in the tube mounting portion 50, and the infusion tube 200 is connected to the tube mounting portion 50 by closing the open / close cover 5. , And can be mounted horizontally along the X direction (T direction). Note that the X direction, the Y direction, and the Z direction in FIGS.
  • the X direction is parallel to the T direction, which is the liquid feeding direction, and is the left-right direction of the infusion pump 1.
  • the Y direction is the front-rear direction of the infusion pump 1.
  • FIG. 3 is a perspective view showing a tube mounting portion 50 for opening the opening / closing cover 5 of the infusion pump 1 shown in FIGS. 1 and 2 and mounting the infusion tube 200.
  • the tube mounting part 50 and the liquid feeding drive part 60 are provided on the main body lower part 1B side of the infusion pump 1, and the tube mounting part 50 and the liquid feeding drive part 60 are operated with the display part 3.
  • a lower portion of the panel portion 4 is provided along the X direction.
  • the tube mounting portion 50 can cover the open / close cover 5 with the open / close cover 5 when the open / close cover 5 is closed in the CR direction around the rotation shaft 5A.
  • the tube mounting portion 50 includes a bubble sensor 51, an upstream blockage sensor 52, a downstream blockage sensor 53, a tube clamp portion 270, a first infusion tube guide portion 54 at the right side position, and a left side position.
  • a second infusion tube guide portion 55 is provided.
  • an infusion tube setting direction display unit 150 for clearly displaying the T direction that is the correct liquid feeding direction when the infusion tube 200 is set is provided in the vicinity of the tube mounting unit 50. ing.
  • the infusion tube setting direction display unit 150 includes, for example, a plurality of arrows 151.
  • the infusion tube setting direction display unit 150 may be printed directly on the lower part of the tube mounting part 50, for example, or may be printed on a seal-like member and attached to the lower part of the tube mounting part 50.
  • the infusion tube setting direction display unit 150 is arranged to clearly indicate the liquid feeding direction (T direction) in the correct direction of the medicine 171 by the infusion tube 200 set inside the opening / closing cover 5.
  • the infusion tube 200 it is possible to clearly indicate the T direction, which is the direction of drug delivery. For this reason, it can prevent reliably that a medical worker will attach the infusion tube 200 by the reverse direction accidentally.
  • the open / close cover 5 is a plate-like member made of a thin molded resin member in order to reduce the weight of the infusion pump 1. Thereby, the weight of the opening / closing cover 5 can be reduced, and the structure can be simplified.
  • the opening / closing cover 5 has two hinge portions 2H and 2H that allow the tube mounting portion 50 to be covered so as to be openable and closable along the CS direction and the CR direction about the rotation shaft 5A. It is supported with respect to the main body lower part 2B.
  • the two hinge portions 2H and 2H are arranged corresponding to the first hook member 5D and the second hook member 5E, respectively.
  • an opening / closing operation lever 260 is provided at the upper right portion on the surface side of the opening / closing cover 5.
  • an infusion tube pressing member 500 On the inner surface side of the opening / closing cover 5, an infusion tube pressing member 500, a first hook member 5D, and a second hook member 5E are provided.
  • the infusion tube pressing member 500 is disposed as a long rectangular and planar protrusion along the X direction, and the infusion tube pressing member 500 is in a position facing the liquid feeding drive unit 60.
  • the infusion tube pressing member 500 has a flat surface in the X direction along the liquid feeding drive unit 60, and the infusion tube pressing member 500 closes the opening / closing cover 5 in the CR direction, A part of the infusion tube 200 is pressed between them.
  • the medical worker can set the infusion tube 200 on the lower half of the body of the infusion pump 1 along the horizontal direction while confirming the display content displayed on the display unit 3, and the infusion tube 200 is connected to the tube mounting portion. After being set to 50, the opening / closing cover 5 can cover the infusion tube 200.
  • the first hook member 5D and the second hook member 5E are mechanically simultaneously engaged with the fixing portions 1D and 1E on the lower body 1B side, so that the open / close cover 5 is As shown, the tube mounting part 50 of the main body lower part 1B is held in a closed state.
  • the first hook member 5D, the second hook member 5E, and the fixing portions 1D, 1E on the main body lower part 1B side constitute a double hook structure portion 300 of the opening / closing cover 5.
  • the tube clamp part 270 shown in FIG. 3 clamps and closes the middle part of the infusion tube 200 by closing the open / close cover 5.
  • the tube clamp portion 270 is disposed in the vicinity of the left fixed portion 1E and at a position corresponding to the left second hook member 5E.
  • the tube clamp portion 270 can block a part of the infusion tube 200 in the middle.
  • the first infusion tube guide portion 54 is provided on the right side of the main body lower portion 1B, and the second infusion tube guide portion 55 is provided on the left side of the main body lower portion 1B.
  • the first infusion tube guide portion 54 can be held by fitting the upstream side 200A of the infusion tube 200
  • the second infusion tube guide portion 55 can be held by fitting the downstream side 200B of the infusion tube 200
  • the infusion tube 200 can be held. It is held in the horizontal direction along the X direction.
  • the infusion tube 200 held in the horizontal direction is in the T direction along the bubble sensor 51, the upstream block sensor 52, the liquid feed drive unit 60, the downstream block sensor 53, and the tube clamp unit 270. It is fixed by fitting along.
  • the second infusion tube guide portion 55 is a groove portion formed in the side surface portion 1 ⁇ / b> S of the main body lower portion 1 ⁇ / b> B in order to detachably hold a part of the downstream side 200 ⁇ / b> B of the infusion tube 200. is there.
  • the first infusion tube guide portion 54 and the second infusion tube guide portion 55 are provided in the tube attachment portion 50 so that the infusion tube 200 is not sandwiched between the opening / closing cover 5 and the tube attachment portion 50 and crushed. Can be installed securely.
  • the bubble sensor 51 shown in FIG. 3 is a sensor that detects bubbles (air) generated in the infusion tube 200.
  • the bubble sensor 51 flows into the infusion tube 200 from the outside of the infusion tube 200 such as soft vinyl chloride.
  • It is an ultrasonic sensor that monitors bubbles contained in a medicine.
  • the receiving unit monitors the presence or absence of bubbles by detecting the difference in transmittance.
  • the bubble sensor 51 has a pressing member 320 and a receiving member 330.
  • the ultrasonic oscillator is disposed on the pressing member 320.
  • the ultrasonic wave receiver is disposed on the receiving member 330.
  • the upstream blockage sensor 52 shown in FIG. 3 is a sensor that detects whether or not the inside of the infusion tube 200 is blocked on the upstream side 200A of the infusion tube 200, and the downstream blockage sensor 53 is an infusion solution on the downstream side 200B of the infusion tube 200. It is a sensor that detects whether or not the inside of the tube 200 is closed.
  • the upstream blockage sensor 52 and the downstream blockage sensor 53 have the same configuration.
  • the case where the infusion tube 200 is blocked is, for example, a case where the viscosity of the medicine to be delivered is high or the concentration of the medicine is high. As shown in FIG.
  • pressing members 452 and 453 are provided on the inner surface side of the opening / closing cover 5 at positions corresponding to the upstream closing sensor 52 and the downstream closing sensor 53, respectively.
  • the infusion tube 200 of any size among the plural types of infusion tubes 200 having different diameters is attached to the infusion pump 1, when the open / close cover 5 is closed, the upstream side occlusion sensor 52 and the downstream side occlusion sensor 53 are The occlusion state of the infusion tube 200 can be detected.
  • FIG. 4 shows an electrical configuration example of the infusion pump 1.
  • the infusion pump 1 has a main control unit 100 and a sub control unit 400.
  • the liquid feeding drive unit 60 includes a drive motor 61, a cam structure 62 having a plurality of eccentric cams that are rotationally driven by the drive motor 61, and cams (eccentric cams 62A to 62F) of the cam structure 62.
  • a finger 63 having a plurality of fingers to be moved is provided.
  • the cam structure 62 has a plurality of eccentric cams, for example, a plurality of eccentric cams 62A to 62F, and the finger structure 63 has a plurality of fingers 63A to 63F corresponding to the plurality of eccentric cams 62A to 62F. is doing.
  • the plurality of eccentric cams 62A to 62F are arranged with a phase difference from each other, and the cam structure 62 is connected to the output shaft 61A of the drive motor 61.
  • the cam structure 62 supported by the output shaft 61A rotates, and the plurality of fingers 63A to 63F are sequentially moved in the Y direction by a predetermined stroke (top dead center and bottom dead center).
  • the infusion tube 200 is pressed against the infusion tube holding member 500 of the opening / closing cover 5 along the T direction. For this reason, the medicine in infusion tube 200 can be sent in the T direction.
  • the plurality of fingers 63A to 63F sequentially advance and retract by a predetermined stroke in the Y direction, so that the infusion tube 200 moves in the T direction.
  • the medicine in infusion tube 200 can be sent in the T direction. That is, when the plurality of fingers 63A to 63F are individually driven, the plurality of fingers 63A to 63F sequentially press the outer peripheral surface of the infusion tube 200 along the T direction to feed the medicine in the infusion tube 200. .
  • the sub-control unit 400 controls the peristaltic motion of the plurality of fingers 63A to 63F, thereby causing the fingers 63A to 63F to move forward and backward in sequence, so that the wave travels, so that the blocking point of the infusion tube 200 is increased. Is moved in the T direction to squeeze the infusion tube 200 and transfer the medicine.
  • the infusion pump 1 has the main control unit 100 and the sub control unit 400.
  • the main control unit 100 is a first control unit
  • the sub control unit 400 is a second control unit.
  • the main control unit 100 employs a CPU (central control unit) chip
  • the sub-control unit 400 preferably employs an FPGA (Field-Programmable Gate Array).
  • the FPGA is a device that can realize a logic function desired by the user in a short period of time using the user's own computer, and is less expensive than a CPU.
  • the main control unit 100 uses, for example, a one-chip microcomputer to control the overall operation, and includes a ROM (Read Only Memory) 101, a RAM (Random Access Memory) 102, a non-volatile memory 103, and A clock 104 is included.
  • the clock 104 can correct the current time by a predetermined operation, and can acquire the current time, measure the elapsed time of a predetermined liquid feeding operation, measure the reference time of liquid feeding speed control, and the like.
  • the main control unit 100 and the sub control unit 400 shown in FIG. 4 are electrically connected, and perform mutual monitoring and monitoring of peripheral elements. That is, the main control unit 100 monitors abnormal operations (for example, runaway operation) of the sub-control unit 400 and monitors peripheral elements directly connected to the main control unit 100. On the other hand, the sub control unit 400 monitors abnormal operations (for example, runaway operation) of the main control unit 100 and controls and monitors peripheral elements connected to the sub control unit 400.
  • the main control unit 100 illustrated in FIG. 4 is directly connected to the following peripheral elements. Directly connected to the main control unit 100 are a battery monitoring unit 181, a power converter unit 112, and a battery 113.
  • the main control unit 100 is connected to a power switch button 4F, a power switch 111, a display driver 130, a drive motor 61, a speaker 131, a buzzer 132, and an information terminal 600 on the nurse center side.
  • This switch 111 supplies power to the main control unit 100 from one of the power converter unit 112 and the battery 113 by switching between the power converter unit 112 and the battery 113.
  • the power converter unit 112 is connected to a commercial AC power source 115 via an outlet 114.
  • the battery 113 is a rechargeable secondary battery such as a lithium ion battery.
  • the main control unit 100 can charge the battery 113 from the power converter unit 112 by issuing a charge command signal CZ and turning on the charging switch 199.
  • the main control unit 100 cancels the charging command signal CZ, charging of the battery 113 can be stopped.
  • the main control unit 100 is also connected to an upstream blockage sensor 52 and a downstream blockage sensor 53 as necessary. Thereby, the main control unit 100 can also monitor the closed state in the infusion tube 200.
  • the temperature sensor 180 measures the temperature when the battery 113 of the infusion pump 1 is operating, and notifies the main controller 100 of the temperature measurement result as a temperature sensor value (A / D value) TS. Thereby, main controller 100 can detect the abnormal state of battery 113 from the temperature during operation of battery 113.
  • the battery monitoring unit 181 is an integrated circuit for battery monitoring, monitors whether the voltage values obtained from the power converter unit 112 and the battery 113 are within a predetermined value range, and monitors the main control unit 100. A signal QS is supplied. As a result, the main control unit 100 can monitor the charging voltage abnormality of the battery 113.
  • a ROM 185 is connected between the main control unit 100 and the sub control unit 400 shown in FIG. Further, another ROM 190 is connected to the sub-control unit 400.
  • These ROMs 185 and 190 use a kind of semiconductor memory, for example, a flash ROM (Flash ROM). Data can be freely erased and written, and the data contents are not lost even when the power is turned off. .
  • the ROM 185 stores arbitrary data for the main control unit 100 to write from the main control unit 100 to the sub control unit 400 in order to detect an abnormal operation of the sub control unit 400, for example.
  • the ROM 190 stores a program for operating the sub control unit 400.
  • the sub-control unit 400 includes a display unit driver 130, an error display lamp 3W, a speaker 131, a buzzer 132, a bubble sensor 51, an upstream block sensor 52, a downstream block sensor 53, a communication port 140, an operation panel (
  • the operation button 4 is electrically connected to the information terminal 600 on the nurse center side, and these peripheral elements are managed and controlled.
  • An information terminal 600 on the nurse center side is placed in the nurse center 650, and the display unit 3T, error display lamp 3WT, speaker 131T, buzzer similar to the display unit 3, error display lamp 3W, speaker 131, and buzzer 132 described above. 132T.
  • the display unit driver 130 in FIG. 4 drives the display unit 3 according to a command from the main control unit 100 or a command from the sub control unit 400, displays information contents and warning messages illustrated in FIG. 2, and LED (light emitting diode). Turn on the backlight.
  • the error display lamp 3W is turned on when either the main control unit 100 or the sub control unit 400 fails.
  • the speaker 131 can notify various alarm contents by voice according to a command from the main control unit 100 or a command from the sub-control unit 400.
  • the buzzer 132 can notify various alarms by sound according to a command from the main control unit 100 or a command from the sub-control unit 400.
  • a downstream blocking signal S3 indicating that the side is blocked is supplied to the sub-control unit 400.
  • the upstream blockage sensor 52 and the downstream blockage sensor 53 can detect a state in which the internal pressure of the infusion circuit exceeds the set pressure in the infusion pump 1 and the medicine cannot be delivered.
  • the reason why the internal pressure of the infusion circuit exceeds the set pressure in the infusion pump 1 is that when the infusion needle for infusion or the infusion tube 200 is clogged, the infusion tube 200 is crushed or broken, a highly viscous drug This is the case when using.
  • the sub-control unit 400 can communicate bidirectionally with a computer 141 such as a desktop computer through the communication port 140.
  • the computer 141 is connected to a drug database (DB) 160, and drug information MF stored in the drug database 160 is acquired by the sub-control unit 400 via the computer 141, and the sub-control unit 400 It can be stored in the ROM 101.
  • the sub-control unit 400 can display the drug information MF and the like on the display unit 3 shown in FIG. 2, for example, based on the stored drug information MF.
  • FIG. 5 is a flowchart showing an operation example of the infusion pump 1.
  • the main control unit 100 and the sub control unit 400 are activated to perform mutual monitoring and monitoring of peripheral elements. . That is, the main control unit 100 monitors abnormal operations (for example, runaway operation) of the sub-control unit 400 and monitors peripheral elements directly connected to the main control unit 100.
  • the sub-control unit 400 monitors the abnormal operation (for example, runaway operation) of the main control unit 100 and controls and monitors the peripheral elements connected to the sub-control unit 400.
  • the sub-control unit 400 shown in FIG. 4 operates the drive motor 61 of the liquid feeding drive unit 60, the cam structure 62 presses the infusion tube 200, thereby feeding the drug along the liquid feeding direction T. Do.
  • step ST2 the sub-control unit 400 monitors an abnormal operation of the main control unit 100 by a watch dog timer (WDT).
  • WDT watch dog timer
  • the abnormal operation of the main control unit 100 is an abnormality that occurs when the microcomputer used in the main control unit 100 is not operating normally. Therefore, the sub-control unit 400 checks whether the main control unit 100 is operating normally or abnormally using a timer called a watchdog timer.
  • This watchdog timer is one of the methods for checking whether the main control unit 100 is operating normally.
  • a normal processing routine called watchdog timer
  • the watchdog timer starts a timer that is reset by an instruction within a certain period of time, and if the timer has not been reset even after this certain period of time has elapsed. Then, it is determined that the program has entered an abnormal processing routine, and an interruption is generated to detect an abnormal operation of the main control unit 100.
  • the sub-control unit 400 is programmed to execute, for example, a certain command to the main control unit 100 so that the same command is executed again even after a predetermined time elapses.
  • the sub-control unit 400 determines that an abnormality has occurred in the hardware of the main control unit 100. However, the sub control unit 400 does not forcibly reset the operation of the main control unit 100. For this reason, the main control unit 100 plays a higher role with respect to the sub control unit 400, but even if the sub control unit 400 determines that an abnormality has occurred in the hardware of the main control unit 100, Since the main control unit 100 is not necessarily in an abnormal state, the main control unit 100 does not enter the reset state, but executes various countermeasures as shown in step ST3.
  • step ST2 of FIG. 5 when the sub control unit 400 shown in FIG. 4 determines that an abnormality has occurred in the hardware of the main control unit 100, in step ST3, the sub control unit 400 displays the display unit driver 130 of FIG.
  • the display unit driver 130 causes the display unit 3 to display “main control unit 100 (CPU) error”.
  • the display color of the liquid crystal display device of the display unit 3 is changed from, for example, a yellow screen to a “white screen” in order to increase the visibility for the medical staff. “Error” is displayed.
  • the medical staff sees the error display on a “white screen” different from the display color of the normal display unit 3, so that the error of the main control unit 100 can be easily and reliably visually recognized. .
  • step ST3 the sub-control unit 400 turns on the red LED of the error display lamp 3W, turns on the buzzer 132, stops the operation of the drive motor 61, and stops the medicine feeding operation. To do. Further, if necessary, the sub-control unit 400 issues a nurse call signal by issuing a “main control unit 100 (CPU) error” to the medical staff through the speaker 131 by voice. In this step ST3, preferably, the sub-control unit 400 notifies the medical staff of “main control unit 100 (CPU) error” also to the information terminal 600 on the nurse center side.
  • the display color of the liquid crystal display device of the display unit 3 is changed from, for example, a yellow screen to a “white screen” by turning on the backlight, and “CPU Error” is displayed on the “white screen”.
  • the sub-control unit 400 “red-lights” the red LED of the error display lamp 3WT, rings the buzzer 132T, and medically reports “main control unit 100 (CPU) error” by voice through the speaker 131T.
  • a nurse call signal is issued by issuing to a worker.
  • step ST4 the main control unit 100 now monitors the operation abnormality of the sub control unit 400.
  • the main control unit 100 writes arbitrary different data in the register of the sub-control unit 400 to the error check register (WRITE).
  • the main control unit 100 reads the data written in the error check register in the sub control unit 400 (READ).
  • the main control unit 100 verifies (inspects) the data by comparing the written data with the read data.
  • This arbitrary data is stored, for example, in the ROM 185 shown in FIG.
  • the main control unit 100 compares the written data with the read data, and if the written data and the read data are different, the main control unit 100 indicates that the sub-control unit 400 has malfunctioned. Judge that.
  • step ST4 when the main control unit 100 determines that the sub control unit 400 is operating abnormally, the main control unit 100 moves to step ST5 and performs the next operation.
  • step ST5 the main control unit 100 forces the sub control unit 400 to be in a reset state.
  • the main control unit 100 forcibly stops the command operation of the sub control unit 400 by forcing the sub control unit 400 into the reset state.
  • priority is given to safety.
  • the main control unit 100 issues a command to the display unit driver 130 of FIG. 4, and the display unit driver 130 causes the display unit 3 to display “sub control unit 400 (FPGA) error”.
  • FPGA sub control unit 400
  • the display color of the liquid crystal display device of the display unit 3 is changed from a yellow screen to a “white screen”, for example, by turning on the backlight in order to increase the visibility for the medical staff.
  • “FPGA Error” is displayed.
  • step ST5 the main control unit 100 turns on the red LED of the error display lamp 3W to “red light”, sounds the buzzer 132, and stops the operation of the drive motor 61. Further, as necessary, the sub-control unit 400 issues a nurse call signal by issuing a “sub-control unit 400 (FPGA) error” to the medical staff through the speaker 131 by voice. In this step ST5, preferably, the main control unit 100 notifies the medical staff of the “sub control unit 400 (FPGA) error” also to the information terminal 600 on the nurse center side. As a result, the display color of the liquid crystal display device of the display unit 3 is changed from, for example, a yellow screen to a “white screen” by turning on the backlight to display “FPGA Error”.
  • step ST3 the main control unit 100 “red-lights” the red LED of the error display lamp 3WT, sounds the buzzer 132T, and performs a medical “sub-control unit 400 (FPGA) error” by voice through the speaker 131T.
  • a nurse call signal is issued by issuing to a person.
  • step ST4 when the main control unit 100 determines that the sub control unit 400 is not operating abnormally, the main control unit 100 moves to step ST6, and when the infusion pump 1 delivers a predetermined amount of drug to the patient, The normal liquid feeding operation performed so far is stopped.
  • the control for stopping the drive motor 61 of the liquid supply drive unit 60 by the main control unit 100 or the sub-control unit 400 is the same whether the normal liquid supply operation is stopped or the liquid supply operation is stopped in the event of an abnormality. .
  • the flow of feeding the medicine 171 in the infusion tube 200 by the finger structure 63 of the liquid feeding drive unit 60 pressing the infusion tube 200 will be described first.
  • FIG. 6 (A) to 6 (F) show a so-called mid-press type liquid feeding drive unit 60 that pushes the inside of the infusion tube 200 and feeds the medicine 171 by squeezing the infusion tube 200 in the T direction. Show. However, the liquid feeding drive unit 60 feeds the medicine 171 in the infusion tube 200 by pressing the infusion tube 200 without completely crushing it. Thus, in this example, the fingers 63C, 63D, and 63E do not completely crush the infusion tube 200 among the finger structures 63 of the mid-press type liquid feeding drive unit 60. The infusion tube 200 can be crushed by a certain amount within the range where there is little settling, and the required amount of the drug 171 can be accurately fed. In FIG.
  • the infusion tube 200 is completely closed by the finger 63B located at the top dead center, and the drug 171 flows in the infusion tube 200 in the T direction.
  • the inflow of the medicine 171 is stopped, and the infusion tube 200 is completely closed by the finger 63F located at the top dead center, so that a certain amount of the medicine 171 is infused.
  • the finger 63B at the bottom dead center is released from pushing the infusion tube 200, the finger 63E at the top dead center pushes the infusion tube 200, and FIG.
  • the fingers 63D and 63C at the top dead center position push the infusion tube 200 to discharge the medicine 171 in the T direction.
  • the finger 63E and the fingers 63D and 63C that are at the top dead center do not completely crush the infusion tube 200.
  • the finger 63B at the top dead center again completely closes the infusion tube 200 again, and stops the discharge of the medicine 171 in the T direction.
  • the finger 63B at the bottom dead center is released from pushing the infusion tube 200, thereby returning to the initial state of FIG. 6 (A).
  • the main control unit 100 or the sub-control unit 400 causes the finger 63B to reach the top dead center position, and the infusion tube 200 is completely removed.
  • the liquid feeding operation is stopped in a state where the pressure is closed.
  • the delivery is performed with the most downstream finger at the top dead center position (predetermined position). Stop fluid operation.
  • the method for stopping the drive motor with a syringe pump is to stop applying a pulse-shaped input current waveform for two-phase excitation for forward rotation from the motor driver of the stepping motor according to the command of the control unit, Control to stop the forward rotation of the magnet rotor of the drive motor.
  • the main control unit 100 and the sub control unit 400 can monitor each other, and the main control unit 100 can monitor abnormal operation (for example, runaway operation) of the sub control unit 400. 400 can monitor abnormal operation (for example, runaway operation) of the main control unit 100.
  • the main control unit 100 and the sub control unit 400 monitor the following peripheral elements, for example.
  • the main control unit 100 monitors the rotation detection signal of the drive motor 61 via the sub control unit 400 for the rotation abnormality of the drive motor 61 shown in FIG.
  • the main control unit 100 monitors the operating state of the battery 113 by directly monitoring the temperature sensor value (A / D value) TS of the temperature sensor 180 without passing through the sub-control unit 400, thereby causing abnormal operation. Sometimes, for example, it is displayed on the display unit 3 and an alarm is given by the buzzer 132.
  • the main control unit 100 directly obtains the monitoring signal (battery voltage detection value (A / D value)) QS without passing through the sub-control unit 400, thereby monitoring the charging voltage abnormality of the battery 113 and charging voltage abnormality. Is displayed on the display unit 3, for example, and an alarm is given by the buzzer 132.
  • the main control unit 100 monitors the presence / absence of bubbles in the infusion tube by the signal S1 of the bubble sensor 51 via the sub-control unit 400, displays the bubble on the display unit 3, and alerts the buzzer 132, for example. You can also
  • the main control unit 100 is also connected to an upstream blockage sensor 52 and a downstream blockage sensor 53 as necessary. As a result, the main control unit 100 can directly monitor the closed state in the infusion tube 200 by directly obtaining the signal S2 from the upstream blockage sensor 52 and the signal S3 from the downstream blockage sensor 53.
  • the main control unit 100 can also monitor the key input signal when the button (key) of the operation panel 4 is continuously turned on via the sub control unit 400.
  • the infusion pump 1 includes a main control unit 100 and a sub control unit 400 as illustrated in FIG. 4, and an FPGA is used as the sub control unit 400.
  • the battery monitoring unit 181, the power converter unit 112, and the battery 113 are directly connected to the main control unit 100 as peripheral elements, for example. As described above, the battery monitoring unit 181, the power supply converter unit 112, and the battery 113 are directly connected to the main control unit 100 without passing through the sub-control unit 400. It is most important to supply power from the converter unit 112 or the battery 113 to the main control unit 100.
  • the main control unit 100 and the sub control unit 400 perform mutual monitoring, monitor peripheral elements, and use them properly.
  • the main control unit 100 monitors, for example, a situation in which a temperature abnormality of the battery 113 or a charging voltage abnormality of the battery 113 occurs, or a situation in which power is not supplied, as the most important monitoring items regarding safety in use. Therefore, the safety of the patient who receives the liquid can be ensured.
  • the sub-control unit 400 monitors other functions. As a result, the main control unit 100 does not incorporate all the functions described above, but the main control unit 100 and the sub control unit 400 share the functions. For this reason, it is not necessary to use a high-performance and expensive CPU (central processing unit) chip as the main control unit 100, and an inexpensive CPU chip with reduced performance can be used. Even if it is used, the cost of the main control unit 100 can be reduced.
  • a medical pump is a medical pump for feeding a drug to a patient, and includes a main control unit, a main control unit, a motor for feeding the drug, and various types of information.
  • the main control unit and the sub control unit are configured to mutually monitor an abnormal operation.
  • the main control unit can separate the roles of the main control unit and the sub control unit. For this reason, it is possible to ensure the safety when the medical pump delivers the medicine to the patient, and furthermore, it is possible to use an inexpensive central processing unit with reduced performance as the main control unit, thereby reducing the cost.
  • the main control unit can directly monitor the power supply from the battery, which is the most important for the medical pump, and the temperature of the battery from the temperature sensor, so that the medical pump can ensure the safety when sending the medicine to the patient, In addition, since an inexpensive one with reduced performance can be used as the main control unit, the cost can be reduced.
  • the sub control unit When the sub control unit detects an operation abnormality of the main control unit, the sub control unit stops the operation of the motor, and when the main control unit detects an operation abnormality of the sub control unit, the main control unit stops the operation of the motor. Thereby, even if any of the main control unit and the sub-control unit operates abnormally, the operation of the motor can be stopped, so that the liquid feeding operation of the medicine can be stopped, and when the medicine is fed, the main control section Safety can be ensured regardless of whether there is a problem with either of the sub-control unit.
  • a white screen is displayed on the display unit to display an operation error of the main control unit
  • the display unit displays a white screen and displays an abnormal operation of the sub-control unit.
  • the buzzer has a buzzer for notifying the alarm, and the buzzer notifies the alarm when the sub control unit detects an operation abnormality of the main control unit, and notifies the alarm when the main control unit detects the operation abnormality of the sub control unit.
  • the buzzer can notify the alarm, so the medical staff can confirm by hearing whether the main control unit or the sub control unit operates abnormally. can do.
  • a battery monitoring unit that monitors battery charging voltage abnormality is provided, and the temperature sensor is disposed in the battery monitoring unit. Thereby, since the temperature sensor used in the battery monitoring unit is used, there is no need to mount the temperature sensor as a separate part, so the number of parts can be reduced.
  • a display unit for displaying information and an operation panel unit having operation buttons are arranged on the upper part of the main body of the medical pump, and a lower part of the main body of the medical pump is a liquid feeding member for feeding a medicine Is an area to be placed.
  • the medical worker can perform the liquid feeding operation of the medicine by the medical pump while confirming the information on the display unit on the upper part of the main body.
  • the medical worker can operate the operation buttons on the operation panel unit while confirming the information on the display unit on the upper part of the main body.
  • the present invention is not limited to the above embodiment, and various modifications can be made without departing from the scope of the claims.
  • the embodiment of the medical pump of the present invention is the infusion pump 1
  • the present invention is not limited to this, and another embodiment of the medical pump of the present invention may be a syringe pump.
  • This syringe pump is used in, for example, an intensive care unit (ICU), etc., and performs high-accuracy treatment of a liquid such as an anticancer agent, anesthetic agent, chemotherapeutic agent, blood transfusion, etc. for a patient. Used for a relatively long time.
  • the flow rate control of the drug in the syringe pump is precise and superior compared to other infusion pumps.
  • the syringe body filled with the medicine is mounted so that it does not move using the clamp against the syringe pump housing, and the syringe pump presses the syringe pusher to accurately deliver the medicine in the syringe body to the patient side. To do.
  • a plurality of types of syringes having different accommodation amounts are prepared in advance.
  • a medical worker selects a required amount of syringe from a plurality of types of syringes, and attaches the selected amount of syringe to the above-described syringe pump.
  • the outer peripheral surface of the syringe main body is brought into close contact with the inner surface of the concave portion of the syringe pump, and the main body flange can be gripped by the inset portion of the syringe pump.
  • the syringe pump motor is driven, and the pressing member of the syringe pump gradually pushes the pusher flange of the syringe pusher toward the syringe body, so that the medicine in the syringe body is sent to the patient through the tube. It comes to liquefy.
  • a display unit for displaying information and an operation panel unit having operation buttons are arranged, and the lower part of the main body of the syringe pump is a liquid feeding member for feeding a medicine. This is an area where a syringe and a tube connected to the syringe are arranged.
  • the medical worker can perform the liquid feeding operation of the medicine by the syringe pump while confirming the information on the display part of the upper part of the main body. Then, the medical worker can operate the operation buttons on the operation panel unit while confirming the information on the display unit on the upper part of the main body.
  • a part of each configuration of the above embodiment can be omitted, or can be arbitrarily combined so as to be different from the above.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention vise à fournir une pompe médicale, par exemple pompe de perfusion, qui implique la réduction des coûts et qui peut assurer la sécurité lorsque la pompe médicale administre un médicament à un patient. La présente invention concerne par conséquent une pompe de perfusion (1) servant de pompe médicale et comprenant : une unité de commande principale (100) ; une unité de commande auxiliaire (400) qui est électriquement raccordée à l'unité de commande principale (100), un moteur (61) pour l'administration d'un médicament, et une unité d'affichage (3) pour afficher différents types d'informations ; une batterie (113) qui alimente en énergie l'unité de commande principale (100) ; et un capteur de température (180) qui détecte la température de la batterie. La batterie (113) et le capteur de température (180) sont directement raccordés à l'unité de commande principale (100). L'unité de commande principale (100) et l'unité de commande auxiliaire (400) surveillent mutuellement les anomalies de fonctionnement.
PCT/JP2012/006036 2012-09-21 2012-09-21 Pompe médicale WO2014045323A1 (fr)

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Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005516644A (ja) * 2001-10-09 2005-06-09 スコット・ラボラトリーズ・インコーポレイテッド 適切な臨床的発見法に従って意識のある患者の医療または手術手法に伴う苦痛または不安を緩和するための装置および方法
JP2009502109A (ja) * 2005-07-21 2009-01-22 ハンヒ シン 太陽電池を利用した携帯機器充電装置
JP2009521258A (ja) * 2005-12-21 2009-06-04 オプテイスカン・バイオメデイカル・コーポレーシヨン 周期的サンプル抜き取りと体液分析器を伴う被検体検出システムと方法
WO2011125439A1 (fr) * 2010-03-31 2011-10-13 テルモ株式会社 Circuit intégré et instrument médical l'utilisant
JP2012010956A (ja) * 2010-06-30 2012-01-19 Terumo Corp 輸液ポンプ
JP2012010940A (ja) * 2010-06-30 2012-01-19 Terumo Corp 機能補完集積回路、集積回路システムおよびこれらを使用した医療機器

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005516644A (ja) * 2001-10-09 2005-06-09 スコット・ラボラトリーズ・インコーポレイテッド 適切な臨床的発見法に従って意識のある患者の医療または手術手法に伴う苦痛または不安を緩和するための装置および方法
JP2009502109A (ja) * 2005-07-21 2009-01-22 ハンヒ シン 太陽電池を利用した携帯機器充電装置
JP2009521258A (ja) * 2005-12-21 2009-06-04 オプテイスカン・バイオメデイカル・コーポレーシヨン 周期的サンプル抜き取りと体液分析器を伴う被検体検出システムと方法
WO2011125439A1 (fr) * 2010-03-31 2011-10-13 テルモ株式会社 Circuit intégré et instrument médical l'utilisant
JP2012010956A (ja) * 2010-06-30 2012-01-19 Terumo Corp 輸液ポンプ
JP2012010940A (ja) * 2010-06-30 2012-01-19 Terumo Corp 機能補完集積回路、集積回路システムおよびこれらを使用した医療機器

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