WO2014001541A1 - Emballage alimentaire antimicrobien - Google Patents
Emballage alimentaire antimicrobien Download PDFInfo
- Publication number
- WO2014001541A1 WO2014001541A1 PCT/EP2013/063710 EP2013063710W WO2014001541A1 WO 2014001541 A1 WO2014001541 A1 WO 2014001541A1 EP 2013063710 W EP2013063710 W EP 2013063710W WO 2014001541 A1 WO2014001541 A1 WO 2014001541A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- metal
- package
- nanoarray
- packaging material
- nanostructures
- Prior art date
Links
- 230000000845 anti-microbial effect Effects 0.000 title claims abstract description 36
- 235000013305 food Nutrition 0.000 title claims description 33
- 239000004599 antimicrobial Substances 0.000 title claims description 8
- 239000002086 nanomaterial Substances 0.000 claims abstract description 82
- 229910052751 metal Inorganic materials 0.000 claims abstract description 58
- 239000002184 metal Substances 0.000 claims abstract description 58
- 239000005022 packaging material Substances 0.000 claims abstract description 47
- 150000004706 metal oxides Chemical class 0.000 claims abstract description 42
- 229910044991 metal oxide Inorganic materials 0.000 claims abstract description 41
- 230000000813 microbial effect Effects 0.000 claims abstract description 18
- 230000012010 growth Effects 0.000 claims abstract description 16
- 238000000034 method Methods 0.000 claims description 36
- 229920000642 polymer Polymers 0.000 claims description 24
- 238000004806 packaging method and process Methods 0.000 claims description 15
- 239000000758 substrate Substances 0.000 claims description 11
- 239000000463 material Substances 0.000 claims description 10
- 238000011282 treatment Methods 0.000 claims description 10
- 229920001400 block copolymer Polymers 0.000 claims description 8
- 229910021645 metal ion Inorganic materials 0.000 claims description 8
- 150000003839 salts Chemical class 0.000 claims description 8
- 229910052747 lanthanoid Inorganic materials 0.000 claims description 4
- 150000002602 lanthanoids Chemical class 0.000 claims description 4
- 238000001338 self-assembly Methods 0.000 claims description 4
- 229910052723 transition metal Inorganic materials 0.000 claims description 4
- 150000003624 transition metals Chemical class 0.000 claims description 4
- 239000002131 composite material Substances 0.000 claims description 3
- 239000011888 foil Substances 0.000 claims description 3
- 235000021485 packed food Nutrition 0.000 claims description 3
- 230000002401 inhibitory effect Effects 0.000 claims description 2
- 239000010408 film Substances 0.000 description 40
- BQCADISMDOOEFD-UHFFFAOYSA-N Silver Chemical compound [Ag] BQCADISMDOOEFD-UHFFFAOYSA-N 0.000 description 28
- 229910052709 silver Inorganic materials 0.000 description 26
- 239000004332 silver Substances 0.000 description 26
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 24
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 20
- 239000011521 glass Substances 0.000 description 15
- 239000002105 nanoparticle Substances 0.000 description 9
- 241000894006 Bacteria Species 0.000 description 7
- CBENFWSGALASAD-UHFFFAOYSA-N Ozone Chemical compound [O-][O+]=O CBENFWSGALASAD-UHFFFAOYSA-N 0.000 description 7
- 239000002243 precursor Substances 0.000 description 6
- 239000002904 solvent Substances 0.000 description 6
- 241000287828 Gallus gallus Species 0.000 description 5
- 150000001768 cations Chemical class 0.000 description 5
- 230000005764 inhibitory process Effects 0.000 description 5
- 238000004519 manufacturing process Methods 0.000 description 5
- 244000005706 microflora Species 0.000 description 5
- 230000008569 process Effects 0.000 description 5
- SQGYOTSLMSWVJD-UHFFFAOYSA-N silver(1+) nitrate Chemical compound [Ag+].[O-]N(=O)=O SQGYOTSLMSWVJD-UHFFFAOYSA-N 0.000 description 5
- 229920001817 Agar Polymers 0.000 description 4
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 4
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 4
- 239000004793 Polystyrene Substances 0.000 description 4
- 229910021607 Silver chloride Inorganic materials 0.000 description 4
- 239000008272 agar Substances 0.000 description 4
- 230000001580 bacterial effect Effects 0.000 description 4
- 244000005700 microbiome Species 0.000 description 4
- 239000000123 paper Substances 0.000 description 4
- 239000004033 plastic Substances 0.000 description 4
- 229920003023 plastic Polymers 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- HKZLPVFGJNLROG-UHFFFAOYSA-M silver monochloride Chemical compound [Cl-].[Ag+] HKZLPVFGJNLROG-UHFFFAOYSA-M 0.000 description 4
- 238000004528 spin coating Methods 0.000 description 4
- 239000010409 thin film Substances 0.000 description 4
- 241000588724 Escherichia coli Species 0.000 description 3
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 3
- 229920000359 diblock copolymer Polymers 0.000 description 3
- 238000009792 diffusion process Methods 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 150000002739 metals Chemical class 0.000 description 3
- NDVLTYZPCACLMA-UHFFFAOYSA-N silver oxide Chemical compound [O-2].[Ag+].[Ag+] NDVLTYZPCACLMA-UHFFFAOYSA-N 0.000 description 3
- 241000251468 Actinopterygii Species 0.000 description 2
- 241000972773 Aulopiformes Species 0.000 description 2
- 241000193755 Bacillus cereus Species 0.000 description 2
- 240000001817 Cereus hexagonus Species 0.000 description 2
- 229910052684 Cerium Inorganic materials 0.000 description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 description 2
- 244000124853 Perilla frutescens Species 0.000 description 2
- 235000004348 Perilla frutescens Nutrition 0.000 description 2
- FOIXSVOLVBLSDH-UHFFFAOYSA-N Silver ion Chemical compound [Ag+] FOIXSVOLVBLSDH-UHFFFAOYSA-N 0.000 description 2
- 229920006328 Styrofoam Polymers 0.000 description 2
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 description 2
- QRCBIKAZMDBTPZ-UHFFFAOYSA-N [Cd].[Si] Chemical compound [Cd].[Si] QRCBIKAZMDBTPZ-UHFFFAOYSA-N 0.000 description 2
- 239000004411 aluminium Substances 0.000 description 2
- 229910052782 aluminium Inorganic materials 0.000 description 2
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 2
- 150000001450 anions Chemical class 0.000 description 2
- 230000000844 anti-bacterial effect Effects 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- ZMIGMASIKSOYAM-UHFFFAOYSA-N cerium Chemical compound [Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce][Ce] ZMIGMASIKSOYAM-UHFFFAOYSA-N 0.000 description 2
- -1 cerium) Chemical class 0.000 description 2
- 238000011109 contamination Methods 0.000 description 2
- 229910052802 copper Inorganic materials 0.000 description 2
- 239000010949 copper Substances 0.000 description 2
- 239000006185 dispersion Substances 0.000 description 2
- 238000001035 drying Methods 0.000 description 2
- 235000013399 edible fruits Nutrition 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 235000019688 fish Nutrition 0.000 description 2
- 239000002054 inoculum Substances 0.000 description 2
- 229910052742 iron Inorganic materials 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 239000011159 matrix material Substances 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- 229910052757 nitrogen Inorganic materials 0.000 description 2
- 230000003287 optical effect Effects 0.000 description 2
- 229920003229 poly(methyl methacrylate) Polymers 0.000 description 2
- 239000004926 polymethyl methacrylate Substances 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 239000002096 quantum dot Substances 0.000 description 2
- 235000019515 salmon Nutrition 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 229910001961 silver nitrate Inorganic materials 0.000 description 2
- 229910001923 silver oxide Inorganic materials 0.000 description 2
- 239000008261 styrofoam Substances 0.000 description 2
- 230000002110 toxicologic effect Effects 0.000 description 2
- 231100000027 toxicology Toxicity 0.000 description 2
- WFKWXMTUELFFGS-UHFFFAOYSA-N tungsten Chemical compound [W] WFKWXMTUELFFGS-UHFFFAOYSA-N 0.000 description 2
- 229910052721 tungsten Inorganic materials 0.000 description 2
- 239000010937 tungsten Substances 0.000 description 2
- 235000013311 vegetables Nutrition 0.000 description 2
- 235000013618 yogurt Nutrition 0.000 description 2
- 239000011701 zinc Substances 0.000 description 2
- XIOUDVJTOYVRTB-UHFFFAOYSA-N 1-(1-adamantyl)-3-aminothiourea Chemical compound C1C(C2)CC3CC2CC1(NC(=S)NN)C3 XIOUDVJTOYVRTB-UHFFFAOYSA-N 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000019331 Foodborne disease Diseases 0.000 description 1
- 240000002129 Malva sylvestris Species 0.000 description 1
- 235000006770 Malva sylvestris Nutrition 0.000 description 1
- 229910019142 PO4 Inorganic materials 0.000 description 1
- 241000589540 Pseudomonas fluorescens Species 0.000 description 1
- 244000061456 Solanum tuberosum Species 0.000 description 1
- 235000002595 Solanum tuberosum Nutrition 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 229910000831 Steel Inorganic materials 0.000 description 1
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 238000009452 anti-microbial packaging Methods 0.000 description 1
- 238000003491 array Methods 0.000 description 1
- 239000012298 atmosphere Substances 0.000 description 1
- 238000004630 atomic force microscopy Methods 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 235000013361 beverage Nutrition 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000003139 biocide Substances 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 239000006285 cell suspension Substances 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- QQZMWMKOWKGPQY-UHFFFAOYSA-N cerium(3+);trinitrate;hexahydrate Chemical compound O.O.O.O.O.O.[Ce+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O QQZMWMKOWKGPQY-UHFFFAOYSA-N 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 150000003841 chloride salts Chemical class 0.000 description 1
- 235000019219 chocolate Nutrition 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 229920001577 copolymer Polymers 0.000 description 1
- XTVVROIMIGLXTD-UHFFFAOYSA-N copper(II) nitrate Chemical compound [Cu+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O XTVVROIMIGLXTD-UHFFFAOYSA-N 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- IZDJJEMZQZQQQQ-UHFFFAOYSA-N dicopper;tetranitrate;pentahydrate Chemical compound O.O.O.O.O.[Cu+2].[Cu+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O IZDJJEMZQZQQQQ-UHFFFAOYSA-N 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000003618 dip coating Methods 0.000 description 1
- 238000001493 electron microscopy Methods 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 238000001433 helium-ion microscopy Methods 0.000 description 1
- 238000007654 immersion Methods 0.000 description 1
- 238000010348 incorporation Methods 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 150000008040 ionic compounds Chemical class 0.000 description 1
- SZQUEWJRBJDHSM-UHFFFAOYSA-N iron(3+);trinitrate;nonahydrate Chemical compound O.O.O.O.O.O.O.O.O.[Fe+3].[O-][N+]([O-])=O.[O-][N+]([O-])=O.[O-][N+]([O-])=O SZQUEWJRBJDHSM-UHFFFAOYSA-N 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 229910001960 metal nitrate Inorganic materials 0.000 description 1
- 230000002906 microbiologic effect Effects 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 150000002823 nitrates Chemical class 0.000 description 1
- 150000002826 nitrites Chemical class 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 229920002223 polystyrene Polymers 0.000 description 1
- 239000004800 polyvinyl chloride Substances 0.000 description 1
- 229920000915 polyvinyl chloride Polymers 0.000 description 1
- 238000012805 post-processing Methods 0.000 description 1
- 235000012015 potatoes Nutrition 0.000 description 1
- 244000144977 poultry Species 0.000 description 1
- 235000013594 poultry meat Nutrition 0.000 description 1
- 235000015504 ready meals Nutrition 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 235000020989 red meat Nutrition 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000010076 replication Effects 0.000 description 1
- 235000015067 sauces Nutrition 0.000 description 1
- 235000013580 sausages Nutrition 0.000 description 1
- 238000007789 sealing Methods 0.000 description 1
- 239000004065 semiconductor Substances 0.000 description 1
- 235000015170 shellfish Nutrition 0.000 description 1
- 235000011888 snacks Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 235000014347 soups Nutrition 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 239000010959 steel Substances 0.000 description 1
- 150000003467 sulfuric acid derivatives Chemical class 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 238000002525 ultrasonication Methods 0.000 description 1
- 239000002966 varnish Substances 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
- 235000008924 yoghurt drink Nutrition 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
- 239000011787 zinc oxide Substances 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
- B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
- B65D81/28—Applications of food preservatives, fungicides, pesticides or animal repellants
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65B—MACHINES, APPARATUS OR DEVICES FOR, OR METHODS OF, PACKAGING ARTICLES OR MATERIALS; UNPACKING
- B65B25/00—Packaging other articles presenting special problems
- B65B25/001—Packaging other articles presenting special problems of foodstuffs, combined with their conservation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D25/00—Details of other kinds or types of rigid or semi-rigid containers
- B65D25/14—Linings or internal coatings
Definitions
- the invention relates to an antimicrobial package suitable for containing an item susceptible to microbial growth or spoilage.
- the invention relates to an antimicrobial package for comestible products such as food and drink products.
- Microbial contamination of food reduces the quality of food, limits the shelf -life of the food, and increases the risk of food-borne illness to the consumer.
- Contamination occurs primarily on the surface of foods, especially foods such as cheeses and meats.
- prevention of food spoilage is an important varaible when determining profit.
- prevention of food spoilage can prolong the shelf-life of products and thus extend market boundries, resulting in increased profit.
- the growth of microorganisms on food products largely occurs post processing during stroage, therefore the packaging of the ffod is extremely important to the quality and shelf life of the food.
- silver nanoparticles have been recognised as having antimicrobial properties, and have been suggested for use as an antibacterial agent in surgical masks, wound dressings, and cotton fibres, Use in food packaging has also been described - see for exampl Appendini et al, Innovative Food Science & Emerging technologies, 2002, Vol. 3, US6942897, US10/726512, WO2004/012998, and US7311933.
- EP 1932429 describes a food package on a cellulose hydrate base that contains nano-scale additives.
- the involved nano particles measure from 0.5 to 1000 nm in at least one dimension.
- the nano particles can be evenly distributed in the cellulose hydrate matrix, they can be on the surface or they can be concentrated in near-surface areas.
- the invention also contains a procedure for the production of the food package and its use as an artificial sausage skin.
- DE102007044286 concerns a transport container, especially for the transport of food.
- the container is made up of polymeric foam with an anti-bacterial active substance.
- the invention also describes the methodology of the process of manufacturing the food package.
- EP 1972197 describes a procedure for the manufacture of a food package with anti-microbial properties, in which nano-silver is applied to the outer side of the food package or worked into a food package by means of application to various types of varnishes or adhesives.
- This invention also concerns a food package with antimicrobial properties as well as the use of such a container to package (envelope) food.
- the methods described in the three patent documents above all involve an initial step of synthesising nanoparticles as an initial step, and then incorporation of the formed nanoparticles into a polymer to provide an active surface.
- the step of pre -forming, and subsequent handling, of nanoparticles involves significant toxicological challenge.
- the processes involve use of significant amounts of nanoparticles (1-5%).
- the Applicant has solved the above-referenced problem by the provision of a package defining an enclosed space suitable for containing an item, in which an interior of the package comprises a surface bearing an ordered nanopattern or nanoarray of metal or metal oxide nanostructures.
- ordered nanopattern or nanoarray of metal or metal oxide nanostructures should be understood to mean an arrangement of metal or metal oxide structures, for example nanodots or nanolines, that are formed on a surface of a substrate in an equispaced pattern, have dimensions in a nanometre range, and are formed by self-assembly from a microphase separated block copolymer in which one of the polymers selectively incorporates a metal ion salt prior to treatment of the block copolymer to oxidise the metal ion salt and remove the polymers.
- the invention provides a package for an item, typically an item susceptible to microbial growth or spoilage, ideally a comestible product, in which an interior of the package comprises a surface that bears a nanoarray or nanopattern of metal or metal oxide nanostructures.
- a packaging material according to the invention overcomes a number of problems of the prior art.
- the nanostructures are rigidly anchored to the surface on which they are formed, thereby allaying concerns that the nanostructures will be ingested by consumers.
- the invention also provides a package defining an enclosed space containing an item, generally an item susceptible to microbial growth or spoilage, in which an interior of the package comprises a surface bearing a nanopattern or nanoarray of metal or metal oxide nanostructures.
- the invention also relates to a packaging material in the form of a sheet or film, for example a roll of polymeric flim, having a first face and a second face, in which at least a portion of one of the faces of the film comprises a surface bearing a nanopattern or nanoarray of metal or metal oxide nanostructures.
- a packaging material in the form of a sheet or film, for example a roll of polymeric flim, having a first face and a second face, in which at least a portion of one of the faces of the film comprises a surface bearing a nanopattern or nanoarray of metal or metal oxide nanostructures.
- the invention also relates to the use of a packaging material of the invention as an antimicrobial agent, typically an antimicrobial agent against packaged comestible items such as food products.
- the invention also relates to a method of extending the shelf life of a packaged comestible item, typically a food product, which method employs a packaging material at least part of which comprises a surface bearing a nanoarray of metal or metal oxide nanostructures, the method comprising a step of enclosing the comestible item within the packaging material to form a package such that the surface bearing the nanoarray of metal or metal oxide nanostructures is disposed on an interior of the package.
- the surface bearing the nanoarray of metal or metal oxide nanostructures may be integrally formed with the packaging material, or may take the form of an insert.
- the invention also relates to a method of preserving a packaged comestible item, typically a packaged food product, which method employs a packaging material at least part of which comprises a surface bearing a nanoarray of metal or metal oxide nanostructures, the method comprising a step of enclosing the comestible item within the packaging material to form a package such that the surface bearing the nanoarray of metal or metal oxide nanostructures is disposed on an interior of the package.
- the surface bearing the nanoarray of metal or metal oxide nanostructures may be integrally formed with the packaging material, or may take the form of an insert.
- the invention also relates to a method of preventing or inhibiting microbial growth on a comestible item contained within a package, typically a packaged food product, which method employs a packaging material at least part of which comprises a surface bearing a nanoarray of metal or metal oxide nanostructures, the method comprising a step of enclosing the comestible item within the packaging material to form a package such that the surface bearing the nanoarray of metal or metal oxide nanostructures is disposed on an interior of the package.
- the surface bearing the nanoarray of metal or metal oxide nanostructures may be integrally formed with the packaging material, or may take the form of an insert.
- the invention also relates to the use of a substrate having a surface bearing an array of metal or metal oxide nanostructures as a packaging material for an item susceptible to microbial growth or spoilage, especially a comestible item such as a food product.
- the substrate is a material suitable for packaging, such as for example a material formed from a polymeric, paper, foil, material or composites thereof.
- the metals employed for the package, packaging materials, and methods and uses of the invention may be selected from the group consisting of:
- the surface bearing the nanoarray or nanopattern of nanostructures may be an interior surface of the packaging material itself, or it may be an insert that it inserted into the package. Inserts could be, for example, a planar film or card on which the nanoarray of nanostructures is formed.
- the packaging material may be polymeric, for example a polymeric bottle, pouch, tray, wrapper, bag, carton or film, with the nanostructures formed on an interior surface of the material, preferably a portion of the material that in use is in contact with at least a portion of the item.
- the nanoarray or nanopattern of nanostructures has a density on the surface of at least 1 x 10 6 nanostructures/cm 2 , preferably at least 1 x 10 7 nanostructures/cm 2 , preferably at least 1 x 10 8 nanostructures/cm 2 , preferably at least 1 x 10 9 nanostructures/cm 2 , preferably at least 1 x 10 10 nanostructures/cm 2 .
- the nanostructures generally have a diameter of from 10- 50nm, preferably 15-30nm, more preferably 20-30nm.
- the centre to centre distance of the nanostructures is 30-60nm, preferably 40-50nm. Characterisation techniques such as atomic force microscopy, secondary electron microscopy, and helium ion microscopy, are employed.
- the nanostructures have a flattened dome shape, such that the edges of the nanodot are not less than one fifth of the height at the centre.
- other types of nanostructures are envisaged, for example lines.
- the nanoarray or nanopattern of nanostructures is ordered (i.e. in an eqispaced pattern), and ideally periodically ordered.
- periodicically ordered should be understood to mean that the system exhibits a pattern formed that has both short range and long range order. In this way the local pattern is reproduced so that the spacing of features is uniform in any chosen direction across the substrate.
- the nanoarray of nanostructures may be provided in a pattern, for example having a round, oval, square, rectangular, triangular, or any other shape.
- the surface may bear a plurality of nanoarrays, for example a pattern of dots on the surface in which each dots comprises a nanoarray of nanostructures.
- the metal is a transition metal (i.e. iron, copper, silver, nickel, aluminium, tungsten, silicon cadmium) or a lanthanide (i.e. cerium), although other metals may be employed in the present invention.
- the metal is silver.
- metal oxide as employed herein should be understood to mean a chemical compound containing a metal and an anion of oxygen typically in a -2 state.
- the metal is selected from a transition metal (i.e. iron, copper, silver, nickel, aluminium, tungsten, silicon cadmium) or a lanthanide (i.e. cerium), although other metals may be employed in the present invention.
- a transition metal i.e. iron, copper, silver, nickel, aluminium, tungsten, silicon cadmium
- a lanthanide i.e. cerium
- metal ion salt should be understood to mean an ionic compound comprising a salt- forming metal cation and a salt-forming cation.
- salt-forming anions include nitrates, nitrites, phosphates, sulphates, chlorides and carbonates.
- the metal ion salt is a metal nitrate, for example iron (III) nitrate nonahydrate, cerium nitrate hexahydrate, and copper nitrate hemipentahydrate.
- item susceptible to microbial growth or spoilage should be understood to mean an item that supports microbial growth in a packaged environment.
- comestible products such as food and drink products, including red meat, poultry, fish, shellfish, vegetables, fruit, ready-made meals, dairy products, yoghurts, yoghurt drinks, fruit drinks, confectionary products.
- Various forms of packages may incorporate a surface bearing a nanopattern or nanoarray of metal or metal oxide nanostructures, for example: film packaging, where the item is wrapped in the film and an interior face of the film provides the surface bearing the metal nanostructures - the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film;
- the nanostructures may be formed on the tray, an interior surface of the film, or both, and the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film or the tray;
- TETRAPAK packs generally for drinks, milk, soups, sauces, yoghurts, in which the nanostructures are generally formed on an inner surface of the pack - the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film; plastic wrappers, for example wrappers for chocolate bars or plastic wrapping for snacks, where the nanostructures are generally formed on an inner surface of the pack - ; the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film
- plastic bag type packages such as those employed to pack potatoes and vegetables, where the nanostructures are generally formed on an inner surface of the pack- the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film;
- the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film;
- plastic bottles or vials of the type employed to contain beverages or liquid samples, where the nanostructures are generally formed on an inner surface of the bottle, and typically disposed on a part of the inner surface of the bottle that in use is in contact with the item contained within the bottle.
- the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film;
- the nanostructures are generally formed on an inner surface of the pack - the antimicrobial surafce may extend across all, some or only a portion of the interior face of the film;
- the surface bearing a nanopattern or nanoarray of metal or metal oxide nanostructures may be integral with the packaging material, or may be separate from the packaging material, for example an insert in the form of, for example, a sheet of card or polymer.
- the insert may be disposed within the package such that in use substantially all or a part of the insert abuts at least a part of the item.
- the surface bearing the nanopattern or nanoarray is preferably disposed within the packaging such that it abuts the item contained within the package.
- substantially all or a portion of the surface bearing the nanoarray of metal or metal oxide nanostructues generally abuts substantially all or a portion of the item contained wirthin the packaging.
- the packages of the invention ideally enclose the packaged item, This means that they fully or partially enclose the item.
- Nanorrays of metal or metal oxide nanostructures are created from a simple block copolymer self-assembly technique. Briefly, a thin film of a microphase separating solution is applied to a substrate (ceramic, metal, glass, polymer and films thereof) which is then treated by heating and/or solvent exposure to induce microphase separation into an ordered nanopattern. The so-formed film is then subject to exposure to a solvent containing metal cations. The solvent is chosen so that it selectively swells one block allowing the metal cations to enter one block. The substrate is removed and dried and placed under a UV/ozone atmosphere for a period of time. During this, the metal cations are oxidized to a solid oxide replication the polymer pattern formed by the microphase separation.
- the remaining polymer material is also oxidized in the treatment to C02 so that a surface containing nanodots of metal oxide may be formed. Reduction to metal (from the oxide) can be achieved by exposure to reducing gas.
- the nanodots formed are well-adhered to the surface, robust, thermally stable and of uniform size. Nanodot sizes of 5nm to lOOnm in diameter can be formed by choice of block copolymer.
- Microscopic glass substrates were cleaned by ultrasonication in ethanol and toluene for 30 min each and dried under a nitrogen stream.
- PS-b-PEO was dissolved in toluene to yield 0.9 wt polymer solution at room temperature and this solution was aged for 12 hours.
- the PS-b-PEO thin film was fabricated by spin coating the polymer solution at 3000 rpm for 30 sec on Si wafer.
- the film was exposed to toluene/water (50:50, v/v) mixed vapour placed at the bottom of a closed vessel kept at 50°C for lh to induce mobility and allow microphase separation to occur. Separate reservoirs were used for each solvent to avoid azeotropic effects.
- the resultant phase separated film was immersed in ethanol at 40°C for 15h.
- silver and zinc oxide nanodots silver nitrate (AgN0 3 ) and zinc nitrate hexahydrate (Zn(N0 3 ) 2 ,6H 2 0) were used respectively.
- 0.6wt and lwt concentrations of silver and zinc precursors were dissolved in ethanol respectively and spin coated onto the nanoporous film.
- UV/Ozone treatment (3h) was used in order to oxidize the precursor as well as to remove polymer residues.
- the spin coating of the precursors and UV/Ozone treatment were repeated four times in order to increase the concentrations of the resultant nanodots.
- a polymethylmethacrylate (PMMA) 400 micron thick film was cleaned by immersion in ethanol and ultrasonicated in the same solvent for 10 min. The film then dried under a nitrogen stream.
- PS-b-P4VP was dissolved in toluene to yield 0.5 wt polymer solution at room temperature and was ultrasonicated for 10 min to ensure dispersion of the polymer.
- the PS-b-P4VP thin film was fabricated by spin coating the polymer solution at 3000 rpm for 30 sec on Si wafer. The film was exposed to toluene vapour placed at the bottom of a closed vessel kept at 50°C for 2 h to induce chain mobility and allow microphase separation to occur. The film was immediately removed and placed in a similar arrangement so that the film was exposed to ethanol vapour for 20 min. The sample was removed and placed into ethanol containing 0.5 weight percent silver nitrate at 40°C for 15 min.
- the film was removed and dipped into clean ethanol for around 10 s. This was repeated twice before drying of the film.
- UV/Ozone treatment (lh) was used in order to oxidize the precursor as well as to remove polymer residues.
- the spin coating of the precursors and UV/Ozone treatment were repeated four times in order to increase the concentrations of the resultant nanodots.
- PS-b-P4VP diblock copolymer The same PS-b-P4VP diblock copolymer described in example 2 was used here.
- a sheet (30 cm x 30 cm) of aluminized polyvinylchloride food was cleaned by exposing to a UV/ozone mixture for 10 min.
- PS-b-P4VP was dissolved in toluene to yield 0.25 wt polymer solution at room temperature and was ultrasonicated for 10 min to ensure dispersion of the polymer.
- the PS-b-P4VP thin film was fabricated by dip coating the sheets into the polymer solution and removing when a knife edge was drawn across the film to remove excess solution.
- the sheet was exposed to toluene vapour by placing the sheet on a self-supporting gauze support 1 cm above the bottom of a tray containing toluene.
- the tray was covered and sealed with a steel lid. All solvent treatments were a room temperature for a period of 2 h
- the sheet was removed and placed in a similar arrangement so that the film was exposed to ethanol vapour for 20 min.
- the sample was removed and placed into ethanol containing 0.25 weight percent copper nitrate at 20°C for 15 min.
- the film was removed and dipped into clean ethanol for around 10 s. this was repeated twice before drying of the film.
- UV/Ozone treatment (lh) was used in order to oxidize the precursor as well as to remove polymer residues.
- the antimicrobial activity of the glass slides containing silver nanoarrays as produced according to Example 1 was carried out by agar diffusion method and viable cell count method.
- the sensitivity of bacterial strains (Gram-positive and Gram-negative bacteria) commonly present in food products and native microflora from chicken to the glass slides containing silver nanoarrays were determined by the agar diffusion method.
- Prior to use glass slides contaianing and not containing silver nanoarray were sterilised in a laminar flow using UV. The slides were then aseptically placed on the surface of the inoculated Muller Hinton agar (MHA) with 0.1 ml of inocula containing indicator microorganisms in the range of 10 6 CFU/ml.
- MHA Muller Hinton agar
- E. coli Escherichia coli
- NCIMB 11943 Staphylococcus aureus
- S. aureus Staphylococcus aureus
- NCIMB 13062 Bacillus cereus
- B. cereus Bacillus cereus
- NCIMB 9373 Bacillus cereus
- Pseudomonas fluorescences Ps. fluorescences
- NCIMB 9046 A microflora isolated from raw chicken sourced locally was also used.
- Each strain was subcultured twice in 10 mL of Muller Hinton Broth and incubated at 30 for Ps. Fluorescens and B. cereus or 37°C for E. coli and S.
- Inoculums of cell suspension in a flask with glass slides without silver nanoarrrays were used as a control.
- the flasks were incubated using an orbital shaker and rotated at 168 rpm at 30 or 37°C and aliquots of 1.5 ml were taken from the flasks and optical density at 610 nm measure every using a UV -visible spectrophotometer. The changes in the optical density were monitored for up to 36 hr.
- the susceptibility of the native microflora obtained from chicken and pure bacterial strains to the silver nanoarray glass slides as determined by the agar diffusion method are presented in Table 1.
- the silver nanoarray showed antimicrobial effect against all bacteria tested (Gram (+) and Gram (-) bacteria) including chicken microflora. Inhibition zones were noticed in all bacterial strains tested and the most susceptible microorganism to the silver nanoarrays was Ps. fluorescence followed by S. aureus. A spore forming bacteria (Bacillus cereus) was also inactivated, indicating that the silver nanoarrays are a powerful antimicrobial with a wide spectrum. After measuring the inhibition zone area, plates were stored for up to 7 days and the inhibition zone area was measured again. The area of the inhibition zone did not change after 7 days storage indicating that the bacteria are inactive and possibly death and the effect of the silver nanoarrays is biocide and not only bacterisotatic.
- the antimicrobial activity of the glass slides containing silver nanoarrays against Ps. Fluorescens and S. Aureus using a viable cell growth in liquid media is shown in Table 2.
- Table 2 Antimicrobial activity of glass slides containing silver nanoarrays against Gram (+) and Gram (-) bacteria.
- a beef steak was packaged in a Styrofoam tray, and the steak and tray were wrapped within the activated film formed according to Example 3.
- the surface bearing the nanoarray of nanostructures covers an area of approximately 5cm 2 , with the nanostructures provided by nanodots having an average diameter of approximately 20nm, and arranged at a density of approximately 1 x 10 8 nandots/cm 2 .
- the surface bearing the nanoarray of silver chloride nanodots abuts a top surface of the steak.
- a simlar steak was packaged in similar packaging but without the array of nanodots on the film. Both packages were stored for five days at refridgeration conditions, and the microbial load on the steaks sampled at days 3, 4, and 5.
- a beef steak was packaged in a Styrofoam tray, and the steak and tray were wrapped within the activated film formed according to Example 3.
- a stiff polymeric insert was placed on a top surface of the meat, the insert bearing a nanoarray of silver chloride nanostructures on a surface of the insert that bears against the meat.
- the surface bearing the nanoarray of nanostructures covers an area of approximately 5cm 2 , with the nanostructures provided by nanodots having an average diameter of approximately 20nm, and arranged at a density of approximately 1 x 10 8 nandots/cm 2 .
- a simlar steak was packaged in similar packaging but without the array of nanodots on the film insert. Both packages were stored for five days at refridgeration conditions, and the microbial load on the steaks sampled at days 3, 4, and 5.
- a salmon steak was packaged in heat sealable poly-coated foil paper packaging material bearing a nanoarray of silver chloride nanostructures on an interior surface of the material.
- the surface bearing the nanoarray of nanostructures covers an area of approximately 5cm 2 , with the nanostructures provided by nanodots having an average diameter of approximately 20nm, and arranged at a density of approximately 1 x 10 8 nandots/cm 2 .
- the surface bearing the nanoarray of silver chloride nanodots abuts a top surface of the salmon steak.
- a simlar steak was packaged in similar packaging but without the array of nanodots on the film insert.
Landscapes
- Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Food Science & Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
- Packages (AREA)
Abstract
Emballage comprenant un matériau d'emballage délimitant un espace fermé approprié pour contenir un élément prédisposé à la détérioration ou au développement de microbes. Un intérieur de l'emballage comprend au moins une surface antimicrobienne portant un nano-ensemble ordonné de nanostructures métalliques ou d'oxyde métallique. Un matériau d'emballage se présentant sous la forme d'une feuille ou d'un film comportant une première face et une seconde face, au moins une partie de l'une des première et seconde faces du film comprenant une surface portant un nano-ensemble de nanostructures métalliques ou d'oxyde métallique, est également décrit.
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP13741687.1A EP2867136A1 (fr) | 2012-06-29 | 2013-06-28 | Emballage alimentaire antimicrobien |
US14/409,254 US20150175336A1 (en) | 2012-06-29 | 2013-06-28 | Antimicrobial food package |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP12174480.9 | 2012-06-29 | ||
EP12174480.9A EP2679516A1 (fr) | 2012-06-29 | 2012-06-29 | Emballage alimentaire antimicrobien |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2014001541A1 true WO2014001541A1 (fr) | 2014-01-03 |
Family
ID=48874997
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2013/063710 WO2014001541A1 (fr) | 2012-06-29 | 2013-06-28 | Emballage alimentaire antimicrobien |
Country Status (3)
Country | Link |
---|---|
US (1) | US20150175336A1 (fr) |
EP (2) | EP2679516A1 (fr) |
WO (1) | WO2014001541A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019229495A1 (fr) | 2018-05-29 | 2019-12-05 | Copperprotek Spa. | Microparticules de cuivre multicomposites microstructurées à activité antibactérienne et/ou biocide comprenant 5 différents types de composés de cuivre |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2594995A1 (fr) * | 2011-11-16 | 2013-05-22 | University College Cork | Procédé de fourniture d'un nano-motif de nanostructures d'oxyde métallique sur un substrat |
WO2016140781A1 (fr) * | 2015-03-05 | 2016-09-09 | Dow Global Technologies Llc | Matériau de conditionnement comprenant une composition antimicrobienne |
WO2019226591A1 (fr) | 2018-05-25 | 2019-11-28 | Cryovac, Llc | Procédé de production d'un film multicouche antimicrobien |
Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000053413A1 (fr) * | 1999-03-06 | 2000-09-14 | Icet, Inc. | Plastiques antimicrobiens |
WO2004012998A2 (fr) | 2002-07-26 | 2004-02-12 | Arkema | Composition pour l'emballage alimentaire a base de resine vinyle aromatique contenant une charge minerale plaquettaire dispersee sous la forme de nanoparticules. |
US6942897B2 (en) | 2003-02-19 | 2005-09-13 | The Board Of Trustees Of Western Michigan University | Nanoparticle barrier-coated substrate and method for making the same |
US20060196623A1 (en) * | 2005-03-07 | 2006-09-07 | Home Round Paper Co., Ltd. | Making of paper product which surface layer possesses bactericidal action |
US7311933B2 (en) | 2004-04-13 | 2007-12-25 | Eastman Kodak Company | Packaging material for inhibiting microbial growth |
EP1932429A1 (fr) | 2006-12-13 | 2008-06-18 | Kalle GmbH | Enveloppes pour aliments à base d'hydrate de cellulose avec nanoparticules |
EP1972129A2 (fr) | 2006-01-11 | 2008-09-24 | Grape Technology Group, Inc. | Système d'assistance-annuaire amélioré à traitement et mise en file d'attente d'appels en périphérie |
EP1972197A2 (fr) | 2007-03-12 | 2008-09-24 | Wiberg GmbH | Emballage de produits alimentaires doté de propriétés antimicrobiennes et son procédé de fabrication |
DE102007044286A1 (de) | 2007-09-07 | 2009-03-12 | Thermohauser Gmbh | Antimikrobiell ausgerüsteter Transportbehälter, insbesondere zur Beförderung von Lebensmitteln |
CN101609743A (zh) | 2008-06-18 | 2009-12-23 | 中国科学院半导体研究所 | 制备平行取向FePt磁性纳米复合薄膜的方法 |
US20100102415A1 (en) | 2008-10-28 | 2010-04-29 | Micron Technology, Inc. | Methods for selective permeation of self-assembled block copolymers with metal oxides, methods for forming metal oxide structures, and semiconductor structures including same |
US20110250745A1 (en) | 2010-04-07 | 2011-10-13 | Dan Millward | Methods of forming patterns, and methods of forming integrated circuits |
-
2012
- 2012-06-29 EP EP12174480.9A patent/EP2679516A1/fr not_active Ceased
-
2013
- 2013-06-28 EP EP13741687.1A patent/EP2867136A1/fr not_active Withdrawn
- 2013-06-28 US US14/409,254 patent/US20150175336A1/en not_active Abandoned
- 2013-06-28 WO PCT/EP2013/063710 patent/WO2014001541A1/fr active Application Filing
Patent Citations (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2000053413A1 (fr) * | 1999-03-06 | 2000-09-14 | Icet, Inc. | Plastiques antimicrobiens |
WO2004012998A2 (fr) | 2002-07-26 | 2004-02-12 | Arkema | Composition pour l'emballage alimentaire a base de resine vinyle aromatique contenant une charge minerale plaquettaire dispersee sous la forme de nanoparticules. |
US6942897B2 (en) | 2003-02-19 | 2005-09-13 | The Board Of Trustees Of Western Michigan University | Nanoparticle barrier-coated substrate and method for making the same |
US7311933B2 (en) | 2004-04-13 | 2007-12-25 | Eastman Kodak Company | Packaging material for inhibiting microbial growth |
US20060196623A1 (en) * | 2005-03-07 | 2006-09-07 | Home Round Paper Co., Ltd. | Making of paper product which surface layer possesses bactericidal action |
EP1972129A2 (fr) | 2006-01-11 | 2008-09-24 | Grape Technology Group, Inc. | Système d'assistance-annuaire amélioré à traitement et mise en file d'attente d'appels en périphérie |
EP1932429A1 (fr) | 2006-12-13 | 2008-06-18 | Kalle GmbH | Enveloppes pour aliments à base d'hydrate de cellulose avec nanoparticules |
EP1972197A2 (fr) | 2007-03-12 | 2008-09-24 | Wiberg GmbH | Emballage de produits alimentaires doté de propriétés antimicrobiennes et son procédé de fabrication |
DE102007044286A1 (de) | 2007-09-07 | 2009-03-12 | Thermohauser Gmbh | Antimikrobiell ausgerüsteter Transportbehälter, insbesondere zur Beförderung von Lebensmitteln |
CN101609743A (zh) | 2008-06-18 | 2009-12-23 | 中国科学院半导体研究所 | 制备平行取向FePt磁性纳米复合薄膜的方法 |
US20100102415A1 (en) | 2008-10-28 | 2010-04-29 | Micron Technology, Inc. | Methods for selective permeation of self-assembled block copolymers with metal oxides, methods for forming metal oxide structures, and semiconductor structures including same |
US20110250745A1 (en) | 2010-04-07 | 2011-10-13 | Dan Millward | Methods of forming patterns, and methods of forming integrated circuits |
Non-Patent Citations (2)
Title |
---|
APPENDINI ET AL., INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES, vol. 3, 2002 |
KUEMMEL ET AL., J. SOL GEL SCI. TECHNOL., vol. 48, 2008 |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2019229495A1 (fr) | 2018-05-29 | 2019-12-05 | Copperprotek Spa. | Microparticules de cuivre multicomposites microstructurées à activité antibactérienne et/ou biocide comprenant 5 différents types de composés de cuivre |
US10570022B2 (en) | 2018-05-29 | 2020-02-25 | Copperprotek Spa | Microstructured multicomposite copper microparticle with antibacterial and/or biocidal activity that comprises in its structure 5 different types of copper compounds, all regular and crystalline |
Also Published As
Publication number | Publication date |
---|---|
EP2867136A1 (fr) | 2015-05-06 |
US20150175336A1 (en) | 2015-06-25 |
EP2679516A1 (fr) | 2014-01-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Scannell et al. | Development of bioactive food packaging materials using immobilised bacteriocins Lacticin 3147 and Nisaplin® | |
Mihaly Cozmuta et al. | Active packaging system based on Ag/TiO2 nanocomposite used for extending the shelf life of bread. Chemical and microbiological investigations | |
Espitia et al. | Zinc oxide nanoparticles for food packaging applications | |
Azlin-Hasim et al. | The potential application of antimicrobial silver polyvinyl chloride nanocomposite films to extend the shelf-life of chicken breast fillets | |
de Azeredo | Antimicrobial nanostructures in food packaging | |
EP2867136A1 (fr) | Emballage alimentaire antimicrobien | |
Lee et al. | Thyme oil encapsulated in halloysite nanotubes for antimicrobial packaging system | |
Gorrasi et al. | Active packaging for table grapes: Evaluation of antimicrobial performances of packaging for shelf life of the grapes under thermal stress | |
Yildirim et al. | Active packaging | |
KR20120109188A (ko) | 그래핀 옥사이드를 유효성분으로 포함하는 항균용 조성물 | |
Wahab et al. | Application of nanotechnology in the packaging of edible materials | |
WO2015197992A1 (fr) | Utilisation de matériaux incorporant des microparticules pour éviter la prolifération de contaminants | |
Srividya et al. | Antimicrobial nanotechnology: Research implications and prospects in food safety | |
Bayani Bandpey et al. | Surface coating of silver nanoparticles on polyethylene for fabrication of antimicrobial milk packaging films | |
US20090041908A1 (en) | Silicon package material | |
Aydemir Sezer et al. | Use of oxidized regenerated cellulose as bactericidal filler for food packaging applications | |
WO2012104844A2 (fr) | Zéolites biocides améliorées | |
Peidaei et al. | Nanotechnology in Food Packaging and Storage: A Review. | |
Azam et al. | Silver nanoparticles loaded active packaging of low-density polyethylene (LDPE), a challenge study against Listeria monocytogenes, Bacillus subtilis and Staphylococcus aurerus to enhance the shelf life of bread, meat and cheese. | |
Abbasi et al. | Comparative study of polyethylene and polyamide packaging containing silver nanoparticles in reduction of meat products (mince meat) microbial load | |
Maćkiw et al. | The Impact of Plasma‐modified Films with Sulfur Dioxide, Sodium Oxide on Food Pathogenic Microorganisms | |
Mathew et al. | Silver-based nanomaterials for food packaging applications | |
Birwal et al. | Nanotechnology applications in packaging of dairy and meat products | |
JP2006104272A (ja) | 抗菌作用を有する樹脂製品 | |
JPH03111264A (ja) | 鮮度保持包装材料 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 13741687 Country of ref document: EP Kind code of ref document: A1 |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2013741687 Country of ref document: EP |
|
WWE | Wipo information: entry into national phase |
Ref document number: 14409254 Country of ref document: US |
|
NENP | Non-entry into the national phase |
Ref country code: DE |