WO2013186735A3 - In-vivo tissue imaging by photothermal detection - Google Patents

In-vivo tissue imaging by photothermal detection Download PDF

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Publication number
WO2013186735A3
WO2013186735A3 PCT/IB2013/054849 IB2013054849W WO2013186735A3 WO 2013186735 A3 WO2013186735 A3 WO 2013186735A3 IB 2013054849 W IB2013054849 W IB 2013054849W WO 2013186735 A3 WO2013186735 A3 WO 2013186735A3
Authority
WO
WIPO (PCT)
Prior art keywords
vivo tissue
tissue imaging
photothermal detection
vivo
tissue
Prior art date
Application number
PCT/IB2013/054849
Other languages
French (fr)
Other versions
WO2013186735A2 (en
Inventor
Moshe Prof. SINVANI
Zeev Prof. ZALEVSKY
Rachela Dr. POPOVTZER
Kobi JAKOBSOHN
Original Assignee
Bar-Ilan Research And Development Company Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bar-Ilan Research And Development Company Ltd. filed Critical Bar-Ilan Research And Development Company Ltd.
Publication of WO2013186735A2 publication Critical patent/WO2013186735A2/en
Publication of WO2013186735A3 publication Critical patent/WO2013186735A3/en

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Classifications

    • H—ELECTRICITY
    • H04—ELECTRIC COMMUNICATION TECHNIQUE
    • H04N—PICTORIAL COMMUNICATION, e.g. TELEVISION
    • H04N5/00—Details of television systems
    • H04N5/30—Transforming light or analogous information into electric information
    • H04N5/33—Transforming infrared radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/01—Measuring temperature of body parts ; Diagnostic temperature sensing, e.g. for malignant or inflamed tissue
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery

Abstract

The present invention provides a method and a system for in-vivo a imaging a tissue with gold nanoparticles inserted therein, the said system and method are based on: a composition of cellular gold nanoparticles, an irradiation device (preferably a 650-900nm laser device) configure to selectively increase the temperature of the nanoparticles and a thermal imaging camera configure to in-vivo Image the tissue.
PCT/IB2013/054849 2012-06-14 2013-06-13 Photothermal detection WO2013186735A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261659444P 2012-06-14 2012-06-14
US61/659,444 2012-06-14

Publications (2)

Publication Number Publication Date
WO2013186735A2 WO2013186735A2 (en) 2013-12-19
WO2013186735A3 true WO2013186735A3 (en) 2014-02-20

Family

ID=49758819

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2013/054849 WO2013186735A2 (en) 2012-06-14 2013-06-13 Photothermal detection

Country Status (1)

Country Link
WO (1) WO2013186735A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10094823B2 (en) * 2015-01-23 2018-10-09 Tokitae Llc Photothermal spectroscopy assay readers, and related assay kits and methods
US9625385B2 (en) 2015-02-24 2017-04-18 Tokitae Llc Photothermal spectroscopy systems for offset synchronous testing of flow assays and methods of using same
AU2017311684B2 (en) 2016-08-14 2023-05-04 Ramot At Tel-Aviv University Ltd. Mesenchymal cell-derived exosomes to treat neurological disorders
JP2021519283A (en) 2018-03-29 2021-08-10 テクニオン・リサーチ・アンド・ディベロップメント・ファウンデーション・リミテッド Vesicles containing PTEN inhibitors and their use
WO2021205459A1 (en) 2020-04-07 2021-10-14 Ramot At Tel-Aviv University Ltd. Cannabidiol-containing compositions and uses thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
WO2003011130A2 (en) * 2001-07-31 2003-02-13 Medisim Ltd. A method for detection of cancer using a thermal enhancement agent, and non-invasive thermal monitoring
WO2003023341A2 (en) * 2001-09-08 2003-03-20 Avecia Limited Thermographic metthod
US20100286674A1 (en) * 2008-01-22 2010-11-11 Board Of Regents, The University Of Texas System Systems, devices and methods for imaging and surgery
TW201039881A (en) * 2009-05-11 2010-11-16 New Vision Inc Laser-excited nanoparticle tumor therapy medical device

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020103517A1 (en) * 2000-02-08 2002-08-01 West Jennifer L. Optically-active nanoparticles for use in therapeutic and diagnostic methods
WO2003011130A2 (en) * 2001-07-31 2003-02-13 Medisim Ltd. A method for detection of cancer using a thermal enhancement agent, and non-invasive thermal monitoring
WO2003023341A2 (en) * 2001-09-08 2003-03-20 Avecia Limited Thermographic metthod
US20100286674A1 (en) * 2008-01-22 2010-11-11 Board Of Regents, The University Of Texas System Systems, devices and methods for imaging and surgery
TW201039881A (en) * 2009-05-11 2010-11-16 New Vision Inc Laser-excited nanoparticle tumor therapy medical device

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
HUNG X. ET AL.: "Cancer Cell Imaging and Photothermal Therapy in the Near-Infrared Region by Using Gold Nanorods", J. AM. CHEM. SOC., vol. 128, no. 6, 21 January 2006 (2006-01-21), pages 2115 - 2120 *
JAKOBSOHN K. ET AL.: "Towards real-time detection of tumor margins using photothermal imaging of immune-targeted gold nanoparticles", INTERNATIONAL JOURNAL OF NANOMEDICINE, vol. 7, 28 August 2012 (2012-08-28), pages 4707 - 4713 *
PERETZ V. ET AL.: "The Effect of Nanoparticle Size on Cellular Binding Probability", JOURNAL OF ATOMIC, MOLECULAR, AND OPTICAL PHYSICS, vol. 2012, 9 April 2012 (2012-04-09) *

Also Published As

Publication number Publication date
WO2013186735A2 (en) 2013-12-19

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