WO2013126027A1 - Magnetic prolonged nail - Google Patents

Magnetic prolonged nail Download PDF

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Publication number
WO2013126027A1
WO2013126027A1 PCT/TR2013/000090 TR2013000090W WO2013126027A1 WO 2013126027 A1 WO2013126027 A1 WO 2013126027A1 TR 2013000090 W TR2013000090 W TR 2013000090W WO 2013126027 A1 WO2013126027 A1 WO 2013126027A1
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WO
WIPO (PCT)
Prior art keywords
nail
screw
spring
bone
magnet
Prior art date
Application number
PCT/TR2013/000090
Other languages
French (fr)
Other versions
WO2013126027A8 (en
Inventor
İstemi̇ Alp Yücel İrşadi̇
Erkut KARACA
Adem AKKUŞ
Original Assignee
Irsadi Istemi Alp Yuecel
Karaca Erkut
Akkus Adem
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Irsadi Istemi Alp Yuecel, Karaca Erkut, Akkus Adem filed Critical Irsadi Istemi Alp Yuecel
Publication of WO2013126027A1 publication Critical patent/WO2013126027A1/en
Publication of WO2013126027A8 publication Critical patent/WO2013126027A8/en

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/56Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
    • A61B17/58Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
    • A61B17/68Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
    • A61B17/72Intramedullary pins, nails or other devices
    • A61B17/7216Intramedullary pins, nails or other devices for bone lengthening or compression
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00017Electrical control of surgical instruments
    • A61B2017/00022Sensing or detecting at the treatment site
    • A61B2017/00039Electric or electromagnetic phenomena other than conductivity, e.g. capacity, inductivity, Hall effect
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00367Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like
    • A61B2017/00411Details of actuation of instruments, e.g. relations between pushing buttons, or the like, and activation of the tool, working tip, or the like actuated by application of energy from an energy source outside the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00Surgical instruments, devices or methods, e.g. tourniquets
    • A61B2017/00982General structural features
    • A61B2017/00991Telescopic means

Definitions

  • the invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries.
  • tubular bone shaft fractures One of the common fractures in Orthopedics and Traumatology is tubular bone shaft fractures. Increased industrialization causes both increasing of traffic accidents and accidents at work. This situation increases incidence of tubular bone shaft fracture especially in young population.
  • tubular bone fractures are often developed due to high-energy trauma, it may be seen with additional injuries. Consequently, death rate is high even in isolated tubular bone fractures.
  • Purpose of treatment of long bone shaft fractures is to provide integrity of extremity (arm or leg) and to provide the functions for the patient earlier.
  • Various treatment methods are available for this purpose and today surgical treatment became standard treatment as a result of complications due to long term fixation seen in preventive treatment and complications due to treatment such as angular-rotational deviation, shortness, joint stiffness and sude atrophy, said various treatment methods don't apply to excessive or heavy treatment attempts. Traction, casting and brace can be used for conservative treatment.
  • External fixation and internal fixation are available amongst surgical treatment methods [osteosynthesis with plate and screw (Putting mechanical devices (screw, wire, nail or plate) in a fractured bone and bringing the ends together and removal process after the fracture union).
  • External fixers provide convenience in wound care in compound fractures but pin tract infection and limitation of movement in adjacent joints are important disadvantages.
  • Advantages of osteosynthesis with plate are; allowing rigid fixation by completely seeing fracture line and allowing earlier movement. But as well as causing a poor image from cosmetic point of view, it causes increase in risk of infection and long boiling time because of large amounts of tissue stripping, fracture hematoma (blood found between the broken bone fragments and starting fracture union) evacuation.
  • Intramedullary nails became golden standard today in treatment of tubular bone shaft fractures because they provide good stabilization, early weight bearing and joint movement, they can be applied by causing less soft tissue injuries, they have less angular and rotational frequency of deformities, they have high fracture union rate.
  • First info about using intramedullary nails in fracture treatment is based on 16 th century. During this period, the Incas and the Aztecs used to drive the resinous wooden nails on medullary canal in treatment of non-union long-bone fractures. In 1986 Bircher et al provided fixation by driving the ivory nails on medullary canal.
  • Kiintscher defined the clover leaf-shaped nails used today and emphasized on difficulty of providing integrity of closed reduction and intramedullary canal
  • Intramedullary nailing is one of the most important surgical inventions in orthopedics history. Long tubular bone shaft fractures can be life-threatening. Today by closed intramedullary nailing while expected union rate in these fractures vary between 95%-99%, infection rate is less than 1% (15,23,72). Poor bone fusion (Malunion) as a result of wrong placement of fractures after intramedullary nailing in tubular bone shaft fractures, is very rare. Also, adding locking screws to modem nailing systems, expanded indications of this procedure including separated fractures, remote and proximal shaft fractures (8,14,15). For these reasons, closed locked intramedullary nailing is the preferred treatment method in treatment of long tubular bone shaft fractures. Intramedullary nails used widely today are as follows:
  • Standard intramedullary nails Nails such as Kuntcsher, AO, Schneider, Samson. They work with stability restoration principle by endo-steal contact from multi-points by filling the canal along the length of the bone. Their indication is istmic regional fractures.
  • Rush and Ender nails are in this group. Ender nail is the most used one in this group in child tubular bone shaft fractures. It acts on the principle of three-point. It is used without reamer (hole punch tool and tool for carving medullary (inner) space of long tubular bone),
  • Locked intramedullary nails They are obtained by adding proximal and/or remote locking screws to intramedullary nail. Locking screws are sent to both cortexes. Basically there are two methods in fracture fixation with intramedullary nail.
  • Static locking means placement of proximal and remote locking screws. This method is used in comminuted fractures and in less cortical contact such as for example femur Winquist Hansen Type 3 and 4 fractures.
  • Dynamic locking is defined as placement of one of the proximal or remote locking screws. It is necessary for the fractures in stable and istmic areas such as femur Winquist Hansen Type 1 and 2.
  • Length and rotation is under control in static locking. If dynamic method is especially used in comminuted fractures, it can't control the rotation and the length.
  • Intramedullary nails are designed mainly to ensure load carrying and to minimize the movement in the fracture zone.
  • Locked intramedullary nails can generally be used in open fractures to Type 3a if foreign objects or non-viable tissues are cut out and if wound is cared.
  • External guide is placed on the in bone nail and locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by using x- ray machine in the guidance of external guide after sending the nail to the bone.
  • Locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by using x-ray machine by free-hand technique without external guide after sending the in bone nail to the bone.
  • Locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by seeing the screw holes and by removing a piece of bone from the front side of the bone by placing an external guide on in bone nail after sending the nail to the bone.
  • the invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries characterized with an outer case (1), a nail (2), a magnet (3), a screw (4), a resistance spring (5), a spring blocking part (6), a reducer (7), a one-way locked bearing
  • nail (2) is prolonged by means of magnet (3) moving with magnetic force applied externally, consequently the leg is prolonged.
  • the system consists of an endless screw (4), a nail (2) which is the extending part of the system and which acts as nut in which this screw (4) can enter, one-way locked bearing (8), small spring
  • the system is ready to operate in this state. After the surgery is completed, bone is prolonged by applying magnetic force to the magnet (3) moving by a magnetic force out of the skin after the desired time.

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  • Health & Medical Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Surgical Instruments (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Magnetic Treatment Devices (AREA)

Abstract

The invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries characterized with an outer case (1 ), a nail (2), a magnet (3), a screw (4), a resistance spring (5), a spring blocking part (6), a reducer (7), a one-way locked bearing (8), a spring (9), Distal holes (10) and proximal holes(11).

Description

DESCRIPTION
MAGNETIC PROLONGED NAIL
Technical Field
The invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries. Background of the Invention (Prior Art)
One of the common fractures in Orthopedics and Traumatology is tubular bone shaft fractures. Increased industrialization causes both increasing of traffic accidents and accidents at work. This situation increases incidence of tubular bone shaft fracture especially in young population.
As tubular bone fractures are often developed due to high-energy trauma, it may be seen with additional injuries. Consequently, death rate is high even in isolated tubular bone fractures.
Purpose of treatment of long bone shaft fractures, is to provide integrity of extremity (arm or leg) and to provide the functions for the patient earlier. Various treatment methods are available for this purpose and today surgical treatment became standard treatment as a result of complications due to long term fixation seen in preventive treatment and complications due to treatment such as angular-rotational deviation, shortness, joint stiffness and sude atrophy, said various treatment methods don't apply to excessive or heavy treatment attempts. Traction, casting and brace can be used for conservative treatment.
External fixation and internal fixation are available amongst surgical treatment methods [osteosynthesis with plate and screw (Putting mechanical devices (screw, wire, nail or plate) in a fractured bone and bringing the ends together and removal process after the fracture union). External fixers provide convenience in wound care in compound fractures but pin tract infection and limitation of movement in adjacent joints are important disadvantages. Advantages of osteosynthesis with plate are; allowing rigid fixation by completely seeing fracture line and allowing earlier movement. But as well as causing a poor image from cosmetic point of view, it causes increase in risk of infection and long boiling time because of large amounts of tissue stripping, fracture hematoma (blood found between the broken bone fragments and starting fracture union) evacuation.
Especially after 1980s, popularity of intramedullary nails in treatment of tubular bone shaft fractures, has steadily increased. Intramedullary nails became golden standard today in treatment of tubular bone shaft fractures because they provide good stabilization, early weight bearing and joint movement, they can be applied by causing less soft tissue injuries, they have less angular and rotational frequency of deformities, they have high fracture union rate. First info about using intramedullary nails in fracture treatment is based on 16th century. During this period, the Incas and the Aztecs used to drive the resinous wooden nails on medullary canal in treatment of non-union long-bone fractures. In 1986 Bircher et al provided fixation by driving the ivory nails on medullary canal. In 1913 Koning also used ivory nails in treatment. In 1897 Norwegian Nicolaysen published principles of intramedullary nailing. In 1907 in Belgium Lambotte Klavikula, in 1913 in Germany Schone used method of nail placement on medullary canal in treatment of radius and ulna fractures. During World War 1 , in England Hey- groves used intramedullary nails in fracture treatment. But Kiintscher is the founder of standard intramedullary nails used today. During World War 2, Kiintscher first used V and then Y shaped nails in treatment of femur fractures. First book about intramedullary nailing technique written by Kiintscher and Maatz together, has been published and in this book, Kiintscher defined the clover leaf-shaped nails used today and emphasized on difficulty of providing integrity of closed reduction and intramedullary canal,
Captive soldiers returning home after the World War 2, in 1945 have led American surgeons to learn this technique. American surgeons started to use open reduction technique as radiation dosage exposed during nailing is high. In 1953 Stryker described a hole punch tool and hole roughness remover tool (reamer) and in 1953 Modny designed locking screw nail. In 1960s Kaesman described compression nailing technique. In 1970 Ender carried out fracture treatment with bent nails. In 1988 cloverleaf- shaped nails are started to be used commonly and meanwhile anatomic shape of tubular bones are started to be given to the nails. Today intramedullary nails such as Russel-Taylor, Delta, AO solid nails are being used extensively. Intramedullary nails will be used more commonly in the future because of its several advantages and fewer complications than expected and they will be continuously developed.
There are 2 kinds of treatment method for bone healing as follows:
Conservative treatment
1.1. Traction
1.2. Brace treatment
1.3. Casting
Surgical treatment
2.1. External fixation
2.2. Internal fixation
2.2.1. Intramedullary nailing
2.2.2. Plate fixation
2.2.3. Fixation with screw
2.2.4. Fixation with wire Our invention is related to intramedullary nailing amongst herein surgical treatment methods. Intramedullary nailing is one of the most important surgical inventions in orthopedics history. Long tubular bone shaft fractures can be life-threatening. Today by closed intramedullary nailing while expected union rate in these fractures vary between 95%-99%, infection rate is less than 1% (15,23,72). Poor bone fusion (Malunion) as a result of wrong placement of fractures after intramedullary nailing in tubular bone shaft fractures, is very rare. Also, adding locking screws to modem nailing systems, expanded indications of this procedure including separated fractures, remote and proximal shaft fractures (8,14,15). For these reasons, closed locked intramedullary nailing is the preferred treatment method in treatment of long tubular bone shaft fractures. Intramedullary nails used widely today are as follows:
a) Standard intramedullary nails: Nails such as Kuntcsher, AO, Schneider, Samson. They work with stability restoration principle by endo-steal contact from multi-points by filling the canal along the length of the bone. Their indication is istmic regional fractures.
b) Flexible intramedullary nails: Rush and Ender nails are in this group. Ender nail is the most used one in this group in child tubular bone shaft fractures. It acts on the principle of three-point. It is used without reamer (hole punch tool and tool for carving medullary (inner) space of long tubular bone),
c) Locked intramedullary nails: They are obtained by adding proximal and/or remote locking screws to intramedullary nail. Locking screws are sent to both cortexes. Basically there are two methods in fracture fixation with intramedullary nail.
- Static locking
- Dynamic locking
Static locking means placement of proximal and remote locking screws. This method is used in comminuted fractures and in less cortical contact such as for example femur Winquist Hansen Type 3 and 4 fractures.
Dynamic locking is defined as placement of one of the proximal or remote locking screws. It is necessary for the fractures in stable and istmic areas such as femur Winquist Hansen Type 1 and 2. On some nails, there is dynamic locking screw hole. Locking screw can move in the dynamic screw hole along the long shaft of the bone and thus formation of fracture callus can be accelerated by mobilizing the fracture fragments. Length and rotation is under control in static locking. If dynamic method is especially used in comminuted fractures, it can't control the rotation and the length. Intramedullary nails are designed mainly to ensure load carrying and to minimize the movement in the fracture zone.
Locked intramedullary nails can generally be used in open fractures to Type 3a if foreign objects or non-viable tissues are cut out and if wound is cared.
Locking of intramedullary nails can be carried out by a big professional team as it is very difficult to apply it as the holes on the nail are in the bone. In intramedullary nail locking, holes on the nail can be found by following techniques:
• External guide is placed on the in bone nail and locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by using x- ray machine in the guidance of external guide after sending the nail to the bone. • Locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by using x-ray machine by free-hand technique without external guide after sending the in bone nail to the bone.
• Locking (screwing) process is carried out by applying screw and by determining the screw holes, by drilling them and by seeing the screw holes and by removing a piece of bone from the front side of the bone by placing an external guide on in bone nail after sending the nail to the bone.
Description of the figures
Figure I Perspective view of our invention
Figure 2 Perspective view of our invention in opened form
Figure 3 Detailed perspective view of our invention in combined form Description of the references
1. Outer case
2. Nail
3. Magnet
4. Screw
5. Resistance spring
6. Spring blocking part
7. Reducer
8. One-way locked bearing
9. Spring
10. Distal holes
11. Proximal hole
Description of the invention
The invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries characterized with an outer case (1), a nail (2), a magnet (3), a screw (4), a resistance spring (5), a spring blocking part (6), a reducer (7), a one-way locked bearing
(8) , a spring (9), Distal holes (10) and proximal holes(l 1).
After the system is driven in the leg by intramedullary nail methods, nail (2) is prolonged by means of magnet (3) moving with magnetic force applied externally, consequently the leg is prolonged.
The system consists of an endless screw (4), a nail (2) which is the extending part of the system and which acts as nut in which this screw (4) can enter, one-way locked bearing (8), small spring
(9) which will return this one-way locked bearing (8) to its previous position, magnet (3) rotating the locked bearing (8) by applying force on it, reducer (7), big resistance spring (5) pushing the nail (2) and resisting to pull back force applied by leg muscles and an outer case (1) protecting the system.
Before endless screw (4) is screwed on the prolonged part (2) of the system, resistance spring (5) which will resist to pull back force applied by leg muscles, is attached and endless screw (4) is screwed on the moving part with nail (2). Spring blocking part (6) is put in the other end of the screw (4) to prevent shifting backwards of the spring (5) on the screw (4) and this end of the screw (4) is connected to a reducer (7). Other end of the reducer (7) is mounted in the one-way locked bearing (8). Rotation of the screw (4) is provided by the magnet (3) rotating the one-way locked bearing (8), said magnet moving with an external magnetic force out of one-way locked bearing (8). By putting a small spring (9) under the place on which one-way locked bearing (8) is mounted, it is provided to return the system to its previous position when the force on the system is removed. Screw driving process is made to one-way locked bearing (8) from outside of the bone by drilling the bone and after the outer case (1) of the system is placed. After installing all the parts, the system is fixed to the bone from the proximal hole (1 1) on the outer case (1) and from the distal holes (10) on the nail (2).
The system is ready to operate in this state. After the surgery is completed, bone is prolonged by applying magnetic force to the magnet (3) moving by a magnetic force out of the skin after the desired time.

Claims

L The invention is related to magnetic prolonged nail, embedded in a protective case and moving in said case and provided to rotate by externally applying magnetic force, used in orthopedic bone lengthening surgeries characterized with an outer case (1), a nail (2), a magnet (3), a screw (4), a resistance spring (5), a spring blocking part (6), a reducer (7), a one-way locked bearing (8), a spring (9), Distal holes (10) and proximal holes(l 1).
2. A claim according to claim 1 characterized with an outer case (1) protecting the system and having a proximal hole (1 1 ) on it and a prolonged nail (2), a screw (4), a resistance spring (5), a spring blocking part (6), a reducer (7), a one-way locked bearing (8), a magnet (3) and a spring (9) in it.
3. A claim according to claim 1 characterized with a nail (2) lengthening the bone by means of a magnet (3) in the outer case (1) by bearing within the outer case (1) and having distal holes (10) on it.
4. A claim according to claim 1 characterized with a magnet (3) lengthening the nail (2) and bone by rotating the screw (2) by one-way locked bearing (8) and rotating the one-way locked bearing (8) when applied magnetic force and locating out of the one-way locked bearing (6) within the outer case (1).
5. A claim according to claim 1 characterized with a screw (4) providing lengthening of the nail (2) rotated by rotation of one-way locked bearing (8) by applying an external magnetic force on the magnet (3) within the outer case (1).
6. A claim according to claim 1 characterized with a resistance spring (5) fixed on the screw (4) against the force to applied by leg muscles.
7. A claim according to claim 1 characterized with a spring blocking part (6) prevent escape of resistance spring (5) backwards.
8. A claim according to claim 1 characterized with a reducer (7) providing rotation of the screw (4) with a greater force and rotating by means of one-way locked bearing rotated by the magnet (3) on which an external magnetic force is applied,
9. A claim according to claim 1 characterized with a one-way locked bearing (8) providing rotation of the screw (4) by rotating the reducer (7) rotated by the magnet (3) on which an external magnetic force is applied.
10. A claim according to claim 1 characterized with a spring (9) returning the system to its previous situation after the pressure on the system is removed.
11. A claim according to claim 1 characterized with distal holes (10) located on the nail (2) and fixing the system to bone.
12, A claim according to claim 1 characterized with a proximal hole (1 1) located on the outer case (1 ) and fixing the system to bone.
PCT/TR2013/000090 2012-02-24 2013-02-21 Magnetic prolonged nail WO2013126027A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
TR2012/02105 2012-02-24
TR2012/02105A TR201202105A2 (en) 2012-02-24 2012-02-24 Magnetically extending nail.

Publications (2)

Publication Number Publication Date
WO2013126027A1 true WO2013126027A1 (en) 2013-08-29
WO2013126027A8 WO2013126027A8 (en) 2013-09-26

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8777947B2 (en) 2010-03-19 2014-07-15 Smith & Nephew, Inc. Telescoping IM nail and actuating mechanism
CN106457394A (en) * 2014-04-11 2017-02-22 史密夫和内修有限公司 DMLS orthopedic intramedullary device and method of manufacture
CN107280814A (en) * 2017-07-25 2017-10-24 魏巍 Joint prosthesis
US9918742B2 (en) 2011-05-16 2018-03-20 Smith & Nephew, Inc. Measuring skeletal distraction

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6336929B1 (en) * 1998-01-05 2002-01-08 Orthodyne, Inc. Intramedullary skeletal distractor and method
US20110060336A1 (en) * 2009-09-04 2011-03-10 Ellipse Technologies, Inc. Bone growth device and method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6336929B1 (en) * 1998-01-05 2002-01-08 Orthodyne, Inc. Intramedullary skeletal distractor and method
US20110060336A1 (en) * 2009-09-04 2011-03-10 Ellipse Technologies, Inc. Bone growth device and method

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8777947B2 (en) 2010-03-19 2014-07-15 Smith & Nephew, Inc. Telescoping IM nail and actuating mechanism
US9408644B2 (en) 2010-03-19 2016-08-09 Smith & Nephew, Inc. Telescoping IM nail and actuating mechanism
US9918742B2 (en) 2011-05-16 2018-03-20 Smith & Nephew, Inc. Measuring skeletal distraction
CN106457394A (en) * 2014-04-11 2017-02-22 史密夫和内修有限公司 DMLS orthopedic intramedullary device and method of manufacture
CN107280814A (en) * 2017-07-25 2017-10-24 魏巍 Joint prosthesis
CN107280814B (en) * 2017-07-25 2023-09-29 北京华巍中兴电气有限公司 artificial joint

Also Published As

Publication number Publication date
WO2013126027A8 (en) 2013-09-26
TR201202105A2 (en) 2012-12-21

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