WO2013093931A3 - Nouveaux promédicaments de médicaments phénoliques - Google Patents
Nouveaux promédicaments de médicaments phénoliques Download PDFInfo
- Publication number
- WO2013093931A3 WO2013093931A3 PCT/IN2012/000590 IN2012000590W WO2013093931A3 WO 2013093931 A3 WO2013093931 A3 WO 2013093931A3 IN 2012000590 W IN2012000590 W IN 2012000590W WO 2013093931 A3 WO2013093931 A3 WO 2013093931A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- novel prodrugs
- phenolic drugs
- phenolic
- drugs
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
- C07D489/04—Salts; Organic complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/22—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with hetero atoms directly attached to ring nitrogen atoms
- C07D295/28—Nitrogen atoms
- C07D295/32—Nitrogen atoms acylated with carboxylic or carbonic acids, or their nitrogen or sulfur analogues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
Abstract
La présente invention concerne des nouveaux promédicaments de carbamate contenant un groupe hydrazide de médicaments phénoliques de formule (I), ou un sel pharmaceutiquement acceptable de ceux-ci, ainsi qu'un procédé pour leur préparation.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IN2647MU2011 | 2011-09-19 | ||
IN2647/MUM/2011 | 2011-09-19 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2013093931A2 WO2013093931A2 (fr) | 2013-06-27 |
WO2013093931A3 true WO2013093931A3 (fr) | 2013-08-08 |
Family
ID=48050873
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IN2012/000590 WO2013093931A2 (fr) | 2011-09-19 | 2012-09-06 | Nouveaux promédicaments de médicaments phénoliques |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2013093931A2 (fr) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2015099863A1 (fr) * | 2013-12-27 | 2015-07-02 | Purdue Pharma L.P. | Analogues de la morphinane 6-substitués et 7-substitués, et leurs utilisations |
CN104262352B (zh) * | 2014-09-01 | 2018-06-15 | 中国人民解放军军事医学科学院毒物药物研究所 | 喜树碱衍生物及其医药用途 |
WO2020012248A1 (fr) | 2018-07-13 | 2020-01-16 | Alkermes Pharma Ireland Limited | Nouveaux composés de naphtylényle pour compositions injectables à action prolongée et procédés associés |
US10807995B2 (en) | 2018-07-13 | 2020-10-20 | Alkermes Pharma Ireland Limited | Thienothiophene compounds for long-acting injectable compositions and related methods |
US11186585B2 (en) | 2018-08-17 | 2021-11-30 | Kappa-Pharma LLC | Compositions and methods of enhancing opioid receptor engagement by opioid hexadienoates and optionally substituted hexadienoates |
US10975099B2 (en) | 2018-11-05 | 2021-04-13 | Alkermes Pharma Ireland Limited | Thiophene compounds for long-acting injectable compositions and related methods |
US11439653B1 (en) | 2021-03-30 | 2022-09-13 | Epalex Corporation | Fospropofol formulations |
US11478490B1 (en) | 2021-03-30 | 2022-10-25 | Epalex Corporation | Fospropofol formulations |
US11628178B2 (en) | 2019-03-26 | 2023-04-18 | Epalex Corporation | Fospropofol methods and compositions |
US11547714B2 (en) | 2020-02-05 | 2023-01-10 | Epalex Corporation | Fospropofol salts, methods and compositions |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604463A (en) * | 1983-07-14 | 1986-08-05 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
US20090005352A1 (en) * | 2004-07-12 | 2009-01-01 | Xenoport, Inc. | Prodrugs of Propofol, Compositions and Uses Thereof |
WO2010112942A1 (fr) * | 2009-04-02 | 2010-10-07 | Shire Llc | Nouveaux promédicaments d'opioïdes à base d'acide aminé et de peptide liés à l'acide dicarboxylique et leurs utilisations |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7230A (en) | 1850-04-02 | Machine for hoisting | ||
US4551452A (en) | 1983-12-21 | 1985-11-05 | Pfizer Inc. | Anti-inflammatory 2-methyl-2H-1,2-benzo-(or -thieno-)thiazine-3-carboxamide 1,1-dioxide derivatives, compositions, and method of use therefor |
AU5108596A (en) | 1995-03-14 | 1996-10-02 | Mundipharma Gmbh | Morphine-3-esters |
US6225321B1 (en) | 1997-06-05 | 2001-05-01 | Oliver Yoa-Pu Hu | Long analgesic acting nalbuphine polyester derivative and method of use |
SG172633A1 (en) | 2006-05-26 | 2011-07-28 | Pharmacofore Inc | Controlled release of phenolic opioids |
WO2008036980A1 (fr) | 2006-09-22 | 2008-03-27 | Alltranz Inc. | Promédicaments d'opioïdes administrables de façon transdermique, compositions empêchant l'usage abusif de ceux-ci et procédés d'utilisation de promédicaments d'opioïdes |
WO2009092071A2 (fr) | 2008-01-18 | 2009-07-23 | Shire Llc | Promédicaments à base d'acides aminés et de peptides d'analgésiques phénoliques et leurs utilisations |
-
2012
- 2012-09-06 WO PCT/IN2012/000590 patent/WO2013093931A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4604463A (en) * | 1983-07-14 | 1986-08-05 | Kabushiki Kaisha Yakult Honsha | Camptothecin derivatives and process for preparing same |
US20090005352A1 (en) * | 2004-07-12 | 2009-01-01 | Xenoport, Inc. | Prodrugs of Propofol, Compositions and Uses Thereof |
WO2010112942A1 (fr) * | 2009-04-02 | 2010-10-07 | Shire Llc | Nouveaux promédicaments d'opioïdes à base d'acide aminé et de peptide liés à l'acide dicarboxylique et leurs utilisations |
Non-Patent Citations (3)
Title |
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J. YOON, ET AL.: "Solution and soluble polymer synthesis of 3-aminoimidazoline-2,4-diones", CHEMICAL COMMUNICATIONS, no. 24, December 1998 (1998-12-01), Royal Society of Chemistry, Cambridge, GB, pages 2703 - 2704, XP002162268, ISSN: 0022-4936, DOI: 10.1039/a807067i * |
M. SABURI, ET AL.: "Stereochemical studies of metal chelates. VII. The preparation, stereochemistry and circular dichloism of dinitrocobalt(III) complexes with (3S, 8S)-dimethyltriethylenetetramine and related tetramines", BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, vol. 45, no. 4, 1972, pages 1086 - 1093, XP055067195, ISSN: 0009-2673, DOI: 10.1246/bcsj.45.1086 * |
W. ELGER, ET AL.: "Sulfamates of various estrogens are prodrugs with increased systemic and reduced hepatic estrogenicity at oral application", JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY., vol. 55, no. 3-4, December 1995 (1995-12-01), Elsevier Science, Oxford, GB, pages 395 - 403, XP005348960, ISSN: 0960-0760, DOI: 10.1016/0960-0760(95)00214-6 * |
Also Published As
Publication number | Publication date |
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WO2013093931A2 (fr) | 2013-06-27 |
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