WO2013084070A3 - Salmonella vaccine proteins - Google Patents

Salmonella vaccine proteins Download PDF

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Publication number
WO2013084070A3
WO2013084070A3 PCT/IB2012/002944 IB2012002944W WO2013084070A3 WO 2013084070 A3 WO2013084070 A3 WO 2013084070A3 IB 2012002944 W IB2012002944 W IB 2012002944W WO 2013084070 A3 WO2013084070 A3 WO 2013084070A3
Authority
WO
WIPO (PCT)
Prior art keywords
methods
infection
salmonella spp
salmonella vaccine
vaccine proteins
Prior art date
Application number
PCT/IB2012/002944
Other languages
French (fr)
Other versions
WO2013084070A2 (en
Inventor
Brett B. Finlay
Brian Coombes
Rosana Ferreira
Original Assignee
The University Of British Columbia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The University Of British Columbia filed Critical The University Of British Columbia
Publication of WO2013084070A2 publication Critical patent/WO2013084070A2/en
Publication of WO2013084070A3 publication Critical patent/WO2013084070A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/025—Enterobacteriales, e.g. Enterobacter
    • A61K39/0275—Salmonella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Compositions and methods for the treatment or prevention of Gram negative bacterial, such as Salmonella spp. infection, in a vertebrate subject are provided. The methods provide administering a composition to the vertebrate subject in an amount effective to reduce or eliminate the Salmonella spp. bacterial infection and/or induce an immune response to the protein. Methods for the treatment or prevention of Salmonella spp. infection in a vertebrate are also provided. Other compositions and methods are also disclosed.
PCT/IB2012/002944 2011-12-06 2012-12-06 Salmonella vaccine proteins WO2013084070A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161567526P 2011-12-06 2011-12-06
US61/567,526 2011-12-06

Publications (2)

Publication Number Publication Date
WO2013084070A2 WO2013084070A2 (en) 2013-06-13
WO2013084070A3 true WO2013084070A3 (en) 2013-08-08

Family

ID=48575011

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/002944 WO2013084070A2 (en) 2011-12-06 2012-12-06 Salmonella vaccine proteins

Country Status (1)

Country Link
WO (1) WO2013084070A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103558388B (en) * 2013-10-24 2015-06-10 江南大学 Double-antibody sandwich method for detecting salmonella typhimurium in food based on monoclonal antibodies
CN104792991B (en) * 2015-04-17 2016-08-17 江南大学 The specific diabodies sandwich assay that a kind of detection Salmonella in Food based on monoclonal antibody belongs to
US11236135B2 (en) 2017-04-27 2022-02-01 Helmholtz-Zentrum Fur Infektionsforschung Gmbh Salmonella and immunogenic composition containing the same as well as its use
US11123415B2 (en) 2017-08-16 2021-09-21 Ohio State Innovation Foundation Nanoparticle compositions for Salmonella vaccines

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
GIL-CRUZ ET AL.: "The porin OmpD from nontyphoidal Salmonella is a key target for a protective B1b cell antibody response", PNAS, vol. 106, June 2009 (2009-06-01), pages 9803 - 9808, XP002564409 *
SIMON ET AL.: "Salmonella enterica serovar enteritidis core 0 polysaccharide conjugated to H:g,m flagellin as a candidate vaccine for protection against invasive infection with S. enteritidis", INFECTION AND IMMUNITY, vol. 79, October 2011 (2011-10-01), pages 4240 - 4249, XP002675655 *

Also Published As

Publication number Publication date
WO2013084070A2 (en) 2013-06-13

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