WO2011157573A3 - An enzyme for the preparation of methylmalonate semialdehyde - Google Patents

An enzyme for the preparation of methylmalonate semialdehyde Download PDF

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Publication number
WO2011157573A3
WO2011157573A3 PCT/EP2011/059178 EP2011059178W WO2011157573A3 WO 2011157573 A3 WO2011157573 A3 WO 2011157573A3 EP 2011059178 W EP2011059178 W EP 2011059178W WO 2011157573 A3 WO2011157573 A3 WO 2011157573A3
Authority
WO
WIPO (PCT)
Prior art keywords
enzyme
preparation
methylmalonate semialdehyde
semialdehyde
methylmalonate
Prior art date
Application number
PCT/EP2011/059178
Other languages
German (de)
French (fr)
Other versions
WO2011157573A2 (en
Inventor
Markus PÖTTER
Achim Marx
Steffen Schaffer
Liv Reinecke
Thomas Haas
Original Assignee
Evonik Röhm Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Evonik Röhm Gmbh filed Critical Evonik Röhm Gmbh
Publication of WO2011157573A2 publication Critical patent/WO2011157573A2/en
Publication of WO2011157573A3 publication Critical patent/WO2011157573A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)

Abstract

The subject matter of the invention is an enzyme for the preparation of methylmalonate semialdehyde or malonate semialdehyde, nucleic acids comprising coding sequences for this enzyme, cells which have been transformed with these nucleic acids, and the use of this enzyme.
PCT/EP2011/059178 2010-06-14 2011-06-03 An enzyme for the preparation of methylmalonate semialdehyde WO2011157573A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102010023748.5 2010-06-14
DE102010023748 2010-06-14

Publications (2)

Publication Number Publication Date
WO2011157573A2 WO2011157573A2 (en) 2011-12-22
WO2011157573A3 true WO2011157573A3 (en) 2012-04-26

Family

ID=44351699

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/059178 WO2011157573A2 (en) 2010-06-14 2011-06-03 An enzyme for the preparation of methylmalonate semialdehyde

Country Status (2)

Country Link
TW (1) TW201211253A (en)
WO (1) WO2011157573A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009046623A1 (en) 2009-11-11 2011-05-12 Evonik Röhm Gmbh Use of a protein homologous to a MeaB protein to increase the enzymatic activity of a 3-hydroxycarboxylic acid CoA mutase
UA112980C2 (en) 2011-02-16 2016-11-25 Евонік Дегусса Гмбх RARE Cationites
EP2607490A1 (en) 2011-12-22 2013-06-26 Evonik Industries AG Method for improved separation of a hydrophobic organic solution from an aqueous culture medium
EP2647696A1 (en) 2012-04-02 2013-10-09 Evonik Degussa GmbH Method for aerobic production of alanine or a compound arising using alanine
DE102012207921A1 (en) 2012-05-11 2013-11-14 Evonik Industries Ag Multi-stage synthesis process with synthesis gas
DE102016212497B4 (en) 2015-07-13 2024-04-25 Sk Innovation Co., Ltd. Mutant microorganism comprising a gene encoding methylmalonyl-CoA reductase and its use

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006025821A1 (en) * 2006-06-02 2007-12-06 Degussa Gmbh An enzyme for the production of Mehylmalonatsemialdehyd or Malonatsemialdehyd
DE102007015583A1 (en) * 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg An enzyme for the production of methylmalonyl-coenzyme A or ethylmalonyl-coenzyme A and its use

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5807722A (en) 1992-10-30 1998-09-15 Bioengineering Resources, Inc. Biological production of acetic acid from waste gases with Clostridium ljungdahlii
ATE259881T1 (en) 1999-05-07 2004-03-15 Emmaus Foundation Inc CLOSTRIDIUM STRAINS PRODUCED FROM SUBSTRATE GAS MIXTURES ETHANOL
ES2297492T3 (en) 2003-10-02 2008-05-01 Basf Se A PROCEDURE FOR SEQUENCE SATURATION MUTAGENESIS (SESAM).
US20070275447A1 (en) 2006-05-25 2007-11-29 Lewis Randy S Indirect or direct fermentation of biomass to fuel alcohol
US7704723B2 (en) 2006-08-31 2010-04-27 The Board Of Regents For Oklahoma State University Isolation and characterization of novel clostridial species

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006025821A1 (en) * 2006-06-02 2007-12-06 Degussa Gmbh An enzyme for the production of Mehylmalonatsemialdehyd or Malonatsemialdehyd
DE102007015583A1 (en) * 2007-03-29 2008-10-02 Albert-Ludwigs-Universität Freiburg An enzyme for the production of methylmalonyl-coenzyme A or ethylmalonyl-coenzyme A and its use

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
AUERNIK KATHRYNE S ET AL: "The genome sequence of the metal-mobilizing, extremely thermoacidophilic archaeon Metallosphaera sedula provides insights into bioleaching-associated metabolism", February 2008, APPLIED AND ENVIRONMENTAL MICROBIOLOGY, VOL. 74, NR. 3, PAGE(S) 682-692, ISSN: 0099-2240, XP002656988 *
DATABASE GSP [online] 27 November 2088 (2088-11-27), XP002656986, Database accession no. ATS06791 *
DATABASE GSP [online] 29 May 2088 (2088-05-29), XP002656987, Database accession no. AOG41376 *
DATABASE UniProt [online] 1 October 2001 (2001-10-01), XP002656990, Database accession no. Q97WN3 *
DATABASE UniProt [online] 29 May 2007 (2007-05-29), XP002656989, Database accession no. A4YEN2 *
QUNXIN SHE ET AL: "The complete genome of the crenarchaeon Sulfolobus solfataricus P2", 3 July 2001, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES, NATIONAL ACADEMY OF SCIENCES, WASHINGTON, DC; US, PAGE(S) 7835 - 7840, ISSN: 0027-8424, XP002625002 *

Also Published As

Publication number Publication date
TW201211253A (en) 2012-03-16
WO2011157573A2 (en) 2011-12-22

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