WO2011095766A1 - Manomètre et valve à trois voies - Google Patents

Manomètre et valve à trois voies Download PDF

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Publication number
WO2011095766A1
WO2011095766A1 PCT/GB2011/000131 GB2011000131W WO2011095766A1 WO 2011095766 A1 WO2011095766 A1 WO 2011095766A1 GB 2011000131 W GB2011000131 W GB 2011000131W WO 2011095766 A1 WO2011095766 A1 WO 2011095766A1
Authority
WO
WIPO (PCT)
Prior art keywords
valve
port
configuration
valve member
manometer
Prior art date
Application number
PCT/GB2011/000131
Other languages
English (en)
Inventor
Kate Mandeville
Lisa Stroux
Original Assignee
Imperial Innovations Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Innovations Limited filed Critical Imperial Innovations Limited
Publication of WO2011095766A1 publication Critical patent/WO2011095766A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/34—Trocars; Puncturing needles
    • A61B17/3401—Puncturing needles for the peridural or subarachnoid space or the plexus, e.g. for anaesthesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/0045—Devices for taking samples of body liquids
    • A61B2010/0077—Cerebrospinal fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/06—Measuring instruments not otherwise provided for
    • A61B2090/064—Measuring instruments not otherwise provided for for measuring force, pressure or mechanical tension
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M2039/226—Spindles or actuating means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/24—Check- or non-return valves
    • A61M2039/2433—Valve comprising a resilient or deformable element, e.g. flap valve, deformable disc
    • A61M2039/2446—Flexible disc
    • A61M2039/2466—Flexible disc being fixed in its center
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/24—Check- or non-return valves
    • A61M2039/2473—Valve comprising a non-deformable, movable element, e.g. ball-valve, valve with movable stopper or reciprocating element
    • A61M2039/2486—Guided stem, e.g. reciprocating stopper
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
    • A61M39/22—Valves or arrangement of valves
    • A61M39/223—Multiway valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
    • A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
    • A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
    • A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button

Definitions

  • the present invention relates to a valve for a manometer and to a manometer, in particular although not exclusively for use in lumbar puncture procedures.
  • Lumbar puncture also known as spinal tap in North America
  • the spinal cord lies within the vertebral canal between three layers - the dura, arachnoid mater and pia mater.
  • the dura and arachnoid mater lie in close approximation at the periphery of the canal, whereas the pia mater overlays the spinal cord, thus leaving a space in between the layers called the sub-arachnoid space.
  • This space is filled with cerebrospinal fluid (CSF), which is produced in the brain and contains a number of factors which vary in health and disease.
  • CSF cerebrospinal fluid
  • the subarachnoid space extends below the end of the spinal cord, and so can be accessed safely below this level without damaging the spinal cord .
  • a lumbar puncture aims to gain access to the sub-arachnoid space and the CSF using a spinal needle that penetrates the soft tissue and outer layers.
  • Lumbar puncture is commonly used in the clinical setting to draw CSF from a patient for biochemical, cytological and microbiological testing for the diagnosis of a number of diseases. These include suspected meningitis, subarachnoid haemorrhages and rarer neurological diseases like multiple sclerosis.
  • the procedure may be used to administer drugs into the CSF (via intra-thecal route) for spinal anaesthesia or chemotherapy, or rarely to therapeutically withdraw CSF.
  • CSF pressure An important aspect of the lumber puncture procedure is the measurement of CSF pressure. This has an important diagnostic value, as a rise in CSF pressure may result from inflammatory conditions like meningitis or space-occupying lesions such as a brain haemorrhage which compresses the CSF into the subarachnoid space. It also has a safety role, as some brain abnormalities can be missed on the usual pre-procedure computerised tomography scan, and abnormally high CSF pressure indicates that the procedure must be abandoned. Excessive withdrawal of CSF can lead to the brain dragging down into the vertebral space and death.
  • the measurement of CSF is conventionally carried out using a vertical burette system, or manometer.
  • This connects to the hollow cannula of the spinal needle, which is in the subarachnoid space, using a press-fit connection.
  • This allows CSF to flow out of the subarachnoid space up into the hollow burette, until the external fluid pressure equals the internal pressure.
  • the CSF pressure is then read off the vertical scale in mm H2O.
  • a three-way tap at the base of the manometer is then turned to connect the fluid within the manometer to a collecting spout, which dispenses the CSF into specimen bottles held under this spout.
  • a further turn of the three-way tap dispenses further CSF via the cannula within the subarachnoid space.
  • the manometer is then detached and the stylet replaced in the spinal needle before removal.
  • Figures 1A, IB and 1C depict a perspective view, a front elevation and a cross-section along the line A-A in Figure IB, respectively;
  • Figures 2 A and 2B depict a detailed view of a portion of the cross- section of Figure IB illustrating a telescopic rise pipe and an alternative arrangement, respectively;
  • Figure 3 A depicts a detailed view of the cross-section of Figure 1C illustrating a first three-way valve arrangement
  • Figures 3B and 3C depict cross-sectional views along, respectively, lines G-G and F-F in Figure 3A;
  • Figure 4A depicts a cross-sectional view of a second arrangement for a three-way valve
  • Figure 4B depicts a cross-sectional view along the line D-D in Figure 4A.
  • the manometer comprises a rise pipe 2 secured to a valve body 4 at one end and having an open end 6 through which the rise pipe communicates with surrounding air.
  • the rise pipe 2 has first portion 8 which comprises the open end 6 at one end.
  • the first portion 8 is disposed within a second portion 10, which is secured to the valve body 4 at one end.
  • the first portion 8 is slideable within the second portion 10 to provide a telescopic rise pipe which can be extended to provide an appropriate length for pressure measurement during use and collapsed for shipping and packaging.
  • an end of the second portion 10 adjacent to open end 6 in the collapsed state of the rise pipe 2 has a tapered surface 12 forming, in some embodiments, an angle of approximately 1° relative to the longitudinal direction of the rise pipe, as indicated by the arrows in Figure 2.
  • An end of the first portion 8 opposite the open end 6, has a complimentary tapered surface 14 so as to engage the tapered surface 12 when the rise pipe is fully extended (the first portion 8 being slid out of the second portion 10 as far as possible) and thereby to form a sealed connection between the first portion 8 and the second portion 10 by virtue of an interference fit between the tapered surfaces 12 and 14.
  • a stopper ring 7 is provided around the first portion 8 at the open end 6 to prevent withdrawal of the first portion 8 into the second portion 10 and to provide a grip surface for sulling out the first portion 8.
  • the first portion 8 is dimensioned so that the open end 6 protrudes from the second portion 10 in the fully collapsed configuration to provide the grip surface.
  • the valve body 4 comprises a connector portion 16 for connecting the manometer to a lumbar puncture canula, a securing portion 18 for securing the rise pipe 2 to the valve body 4 and an outlet 20 through which CSF can be dispensed into a suitable receptacle on actuation of the push button 22, as described in more detail below.
  • the rise pipe 2 is secured to the securing portion 18 by an interference fit, thermal bonding or adhesive bonding, although in some embodiments the second portion 10 and valve body 4 may be integrally moulded or co-moulded.
  • the connector portion 16 is shaped to connect to a corresponding canula, for example by a Luer of Luer lock connection, although other connections are of course equally possible.
  • the valve body 4 defines a chamber 24 which can be connected to the connector portion 16 through a connector port 26, to the rise pipe 2 through a rise pipe port 28 and to the outlet 20 through an outlet port 30.
  • the connector port 26 is defined between an inner surface 32 of the chamber 24 and a leading portion 34 adjacent to the connection portion 16 of a moveable valve member 36.
  • a trailing portion 38 of the valve member 36 is disposed through an orifice in a separating wall 40 located between the outlet 20 and the chamber 24.
  • the outlet port 30 is defined between the trailing portions 38 of the valve member 36 and the orifice in the separating wall 40.
  • the valve member 36 comprises a substantially rigid core 42 to provide sufficient rigidity for the valve member 36, surrounded by a resilient polymeric material 44 which is shaped to define a dome shaped structure 46 at its trailing end, a protruding seal portion 48 in the region of the leading portion 34 and, in between, a saucer-shaped further seal portion 50 inside the chamber 24 adjacent to the separating wall 40.
  • the resilient material 44 defines a body of revolution around and centred on the substantially rigid wall 42.
  • the domed member 46 seals against a corresponding seat of the valve body 4 to seal the interior of the valve body 4 from surrounding air with only the connector portion 16, outlet 20 and securing portion 18 providing fluidic communication between the interior of the valve body 4 and its exterior.
  • the domed member 46 in effect, provides a push button membrane sealing against the valve body 4.
  • the domed member 46 comprises a ribbed surface on its exterior aspect to provide a non-slip or reduced-slip surface for the push button 22 and facilitate controlled depression/release, with the valve member 36 extending from the domed member 46 into the valve body 4, through the orifice in the separating wall 40 into the chamber 24.
  • the domed member 46 has a patterned surface other than a ribbed surface, for example or knobbed surface or non-patterned surface.
  • the leading portion 34 of the valve member 36 is disposed adjacent to the connector portion 16 to define the connector port 26 with the sealed portion 48 spaced from the inner surface 32.
  • the further sealed portion 50 is resiliency biased against the separating wall 40 around its orifice.
  • the connection port 26 is connected via the chamber 24 to the rise pipe port 28 via the chamber 24.
  • the leading portion 34 and seal portion 48 are spaced from the connector port 26 and the further sealed portion 50 is spaced from the orifice in the separating wall 40, so that all three ports 26, 28 and 30 are connected to each other via the chamber 24, or in other words are in fluidic communication with each other via the chamber 24, in these intermediate configurations.
  • the valve member 36 Upon partial or full release of the pushing force, the valve member 36 backs off partially or fully, respectively, due to the resilience of the domed member 46, thus enabling repeated actuation of the valve to select a required configuration of the valve.
  • valve member 36 linear movement of the valve member 36 upon exertion by a user of a pushing force on the push button 22 allows the valve member 36 to be disposed in configurations relative to the valve body 4 so as to selectively connect the connector port 26 to the rise pipe 28 via the volume 24 and seal off the outlet port 30, connect the rise pipe port 28 to the outlet port 30 via the volume 24 and seal off the connector port 26 or to connect all three ports together in respective configurations.
  • the manometer is prepared by extending the rise pipe 6 as described above.
  • the connection portion 16 is connected to the canula and, in the absence of a force exerted on the push button 22, the connection port 16 is connected to the rise pipe port 28 with the outlet port 30 being sealed so that CSF flowing under pressure through the connector portion 16 into the chamber 24 rises against gravity in the rise pipe 6 until the gravitational pressure to the liquid column in the rise pipe 6 balances the CSF pressure in the subarachanoid space, at which point a pressure reading can be taken from the graduated scale of the rise pipe, for example in mmH 2 0.
  • valve body 4 can be held between the index and middle fingers between the rise pipe 2 and connector 16, allowing the thumb to be placed on the push button, in a manner similar to actuating a conventional syringe.
  • the push button 22 can be fully released to stop further flow into the receptacle. If all of the liquid in the rise pipe 6 has drained into the receptacle and still further liquid is required, the pressure on the push button 22 can be reduced to an intermediate level to back off the valve member 36 due to the resilience of the domed member 46 to a position intermediate a configuration sealing the outlet port 30 and a configuration sealing the connector port 26, thus allowing CSF to flow directly from the connector 16 through the chamber 24 to the outlet 20 until sufficient CSF has been drawn.
  • valve member 36 can be disposed at intermediate positions, between the three configurations mentioned, by adjusting the pressure applied to the push button 22, the flow rate from the rise pipe 2 and connector portion 16 to the outlet 20 can be controlled from dripping only to fully open by gradually spacing the seal member 50 away from the separating wall 40. Once the rise pipe 40 has emptied, the flow rate from the connector 16 only can additionally be controlled by controlling the position of the seal member 48 relative to the connector port 26 by controlling the pressure on the push button 22.
  • valve body and valve member arrangement replaces the one described above with reference to Figures 3A, 3B and 3C.
  • Like parts have been given like reference numerals.
  • the separating wall 40 is removed so that the chamber 24 occupies the entire interior space of the valve body 4 including the inside of the domed member 46 and a single seal portion 52 sealing and connecting ports on linear movement of the valve member 36 as the push button 22 is depressed replaces the separate seal portions 48 and 50 for sealing, respectively connector port 26 and the outlet port 30.
  • the sealed portion 52 comprises first and second wiper plates 54, 55 which, when no pressing force is applied to the push button 22, are disposed inside the chamber 24 in a first region between the rise pipe port 28 and the outlet port 30 (in the direction of linear movement of the valve member 36) the rise pipe port 28 being disposed on top of the chamber 24 in a working orientation and the outlet port 30 being disposed at the bottom of the chamber 24 in a working orientation.
  • the wiper plates 54, 55 are spaced so that a leading wiper plate 54 is disposed with its top adjacent to the rise pipe port 28 and a trailing wiper plate 55 is disposed with its bottom adjacent to the outlet port 30.
  • the chamber 24 defines a substantially cylindrical shape with the walls of the chamber 24 extending at right angles to a transverse cross-section of the chamber in this region.
  • the wiper plates 54, 55 have a rounded edge 56 which conforms to the inner surface 32 of the chamber 24 in the first region and is a resilient fit with the wall to form a wiping seal in the first region.
  • the transverse cross-section area of the chamber 24 expands so that the wiper plates 54 of the seal portion 52 no longer seal against the inner surface 32 of the chamber 24, so that fluidic communication is established between all three ports when both wiper plates 54 of the sealed portion 52 are disposed in the third region, when the push button 22 is fully depressed.
  • all three ports are connected to each other via the chamber 24.
  • the cross-sectional area of the chamber 24 on either side of the rise pipe port 28 is generally disc shaped with a substantially circular inner perimeter of the chamber 24 extending over most of its angular extent but with an inwardly raised bump of the inner surface 32 extending into the chamber 24 at its bottom in the working orientation.
  • the bump 56 falls away to give rise to the expanded cross- sectional area, so that an indent 58 of the wiper plates 54 corresponding to the bump 56 provides an increased cross-sectional area of the flow path from the connection port 26, as compared to a fully disc shaped wiper plate shape and cross-sectional area throughout.
  • the device is handled substantially as described above, with the rise pipe 2 connected to the connector 16 when no external force is applied to the push button 22 but with the difference that connection of the rise pipe 2 to the outlet 20 while sealing off the connector 16 is achieved not in a fully depressed configuration but in an intermediate configuration, with the push button 22 partially depressed and that all three ports are connected when the push button 22 is fully depressed.
  • a gradual increase of a pressure applied to the push button 22 first leads to a low flow rate, dripping action, from the rise pipe 2, then increases this flow rate and then finally a gradually increasing flow rate from the connector 16 as the valve member 36 is progressively advanced into the chamber 24 of the valve body 4.
  • the valve body 4 includes an arrangement which provides a user with haptic or tactile feedback allowing a user to discern when the valve member 36 is within the intermediate configuration relative to the valve body 4 so that the rise pipe port 28 is connected to the outlet port 30 but both these ports are sealed off from the connector port 26, and when this configuration is left.
  • this haptic or tactile feedback is provided by a rib around the perimeter of the chamber 24 in the second region between the rise pipe port 28 and the connector port 26 and positioned so that the leading wiper plate 54 rides over the rib, but not the trailing wiper plate 55 when the seal portion 52 is pushed passed the rise pipe port 28 sufficiently so that the trailing wiper plate 55 rests adjacent to the rise pipe portion 28 on the side towards the connector port 26. On further depression of the push button to connect the three ports, the trailing wiper plate 55 then also rides over the rib.
  • haptic or tactile feedback in the form of a small resistance to movement of the valve member 36 are provided, once when the push button 22 has been sufficiently depressed to connect the rise pipe port 28 to the outlet port 30, while sealing the connector port 26, and once when all three ports have been connected, and likewise on the return stroke of the valve member 36.
  • the rib can be replaced by one or more nubs or separate feedback features can be provided both on the valve member 36 and the valve body 4, for example separate resilient plates interacting with a separate feature such as a web on the valve body 4.
  • the resistance to movement due to the feedback providing feature must be sufficiently large to be haptically detected by a user but not so large so as to impede the return stroke of the valve member 36 due to the resilience of the domed member 46.
  • the manometers described above may be manufactured using any suitable manufacturing technique, for example the parts of the rise pipe 2 are manufactured by extrusion of a clear plastic material, for example PC (polycarbonate) or PVC (polyvinyl chloride), followed by machining of the tapered surfaces 12, 14, with the valve body injection moulded from a clear plastic such as PC (with the separating wall 40 in the Figure 3 embodiment separately moulded, for example injection moulded from PC, and then assembled), and with the resilient polymeric material 44 being TPC (thermoplastic elastomer), shaped by injection moulding.
  • a clear plastic material for example PC (polycarbonate) or PVC (polyvinyl chloride)
  • the core 42 may be omitted in some embodiments.
  • a PVC or PC rod-shaped member could be placed inside the TPE shape using co-injection moulding. While PC is a preferred material in terms of optical clearness, PVC is also transparent and maybe preferred in some embodiments due to the reduced cost of PVC. Equally envisaged are embodiments which use a blend of PVC and PC for the rise pipe 2 parts and the valve body 4 (and, if applicable separating wall 40).
  • the open end 6 of the first portion 8 is slid into the second portion to protrude from it and the stopper ring 7 is placed over and adhered to the open end 6 to prevent the first portion 8 to slide back into the second portion 10.
  • the resulting assembly can then be assembled with the valve body 2 using a press fit connection, either when the manometer is prepared for use or as a pre-assembly step at manufacture.
  • the valve body 2 is assembled by inserting the valve member 36 into the valve body 4 and a joint line of the valve member 36 with the valve body 4 (around the push button 22) is sealed using an adhesive.
  • the separating wall 40 is secured in place by an adhesive or, alternatively, may be secured by ultrasonic welding or a press-fit.
  • the valve member 36 is then forced through the outlet port 30 into position.
  • adhesive fastening of components is replaced with ultrasonic welding, press fitting or other methods of achieving a sealing fit.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Anesthesiology (AREA)
  • Pulmonology (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne une valve pour manomètre destiné à être utilisé dans des procédures de ponction lombaire, la valve comprenant un élément de valve qui peut être déplacé de manière linéaire par rapport au corps de la valve afin de définir trois configurations pour la valve afin de, respectivement, connecter une conduite montante du manomètre vers une aiguille de ponction lombaire, distribuer le liquide à partir de la conduite montante et distribuer le liquide à partir de la conduite montante et de l'aiguille de ponction lombaire. L'invention concerne également un manomètre de ponction lombaire correspondant et un manomètre de ponction lombaire correspondant ayant une conduite montante télescopique.
PCT/GB2011/000131 2010-02-02 2011-02-01 Manomètre et valve à trois voies WO2011095766A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB1001699.6 2010-02-02
GBGB1001699.6A GB201001699D0 (en) 2010-02-02 2010-02-02 Manometer and three-way valve

Publications (1)

Publication Number Publication Date
WO2011095766A1 true WO2011095766A1 (fr) 2011-08-11

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ID=42084353

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2011/000131 WO2011095766A1 (fr) 2010-02-02 2011-02-01 Manomètre et valve à trois voies

Country Status (2)

Country Link
GB (1) GB201001699D0 (fr)
WO (1) WO2011095766A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015136084A1 (fr) * 2014-03-14 2015-09-17 Fresenius Medical Care Deutschland Gmbh Valve précontrainte pour dispositif fonctionnel médical, et dispositif fonctionnel médical
CN108338825A (zh) * 2018-04-24 2018-07-31 苏州诺来宁医疗科技有限公司 一种一体式安全腰椎穿刺器
GB2577319A (en) * 2018-09-22 2020-03-25 Parmar Sunjay Universal container holding device and procedure aid for spinal fluid sample collection
WO2021196412A1 (fr) * 2020-04-03 2021-10-07 南京汉欣医药科技有限公司 Vanne de régulation de débit pour réguler l'écoulement et le débit de liquide

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081770A (en) * 1960-09-21 1963-03-19 John M Hunter Surgical instrument
AU458487B2 (en) * 1972-05-15 1975-02-27 Liposky, Richard B. Rand operable selector valve
US4534758A (en) * 1983-07-15 1985-08-13 Eli Lilly & Company Controlled release infusion system
EP0576380A1 (fr) * 1992-06-26 1993-12-29 Laboratoire Aguettant Système de connexion stérile
US5396899A (en) * 1993-04-28 1995-03-14 Duke University Spinal puncture fluid collection apparatus
NL9500612A (nl) * 1995-03-30 1996-11-01 Cordis Europ Stopkraan voor medische toepassingen.
US5772607A (en) * 1995-06-06 1998-06-30 The Nemours Foundation Body fluid collection apparatus
US20080108954A1 (en) * 2006-11-02 2008-05-08 Jean-Marie Mathias Flow Controllers

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3081770A (en) * 1960-09-21 1963-03-19 John M Hunter Surgical instrument
AU458487B2 (en) * 1972-05-15 1975-02-27 Liposky, Richard B. Rand operable selector valve
US4534758A (en) * 1983-07-15 1985-08-13 Eli Lilly & Company Controlled release infusion system
EP0576380A1 (fr) * 1992-06-26 1993-12-29 Laboratoire Aguettant Système de connexion stérile
US5396899A (en) * 1993-04-28 1995-03-14 Duke University Spinal puncture fluid collection apparatus
NL9500612A (nl) * 1995-03-30 1996-11-01 Cordis Europ Stopkraan voor medische toepassingen.
US5772607A (en) * 1995-06-06 1998-06-30 The Nemours Foundation Body fluid collection apparatus
US20080108954A1 (en) * 2006-11-02 2008-05-08 Jean-Marie Mathias Flow Controllers

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015136084A1 (fr) * 2014-03-14 2015-09-17 Fresenius Medical Care Deutschland Gmbh Valve précontrainte pour dispositif fonctionnel médical, et dispositif fonctionnel médical
US10357644B2 (en) 2014-03-14 2019-07-23 Fresenius Medical Care Deutschland Gmbh Prestressed valve for a medical functional device and a medical functional device
CN108338825A (zh) * 2018-04-24 2018-07-31 苏州诺来宁医疗科技有限公司 一种一体式安全腰椎穿刺器
CN108338825B (zh) * 2018-04-24 2023-05-26 苏州诺来宁医疗科技有限公司 一种一体式安全腰椎穿刺器
GB2577319A (en) * 2018-09-22 2020-03-25 Parmar Sunjay Universal container holding device and procedure aid for spinal fluid sample collection
GB2577319B (en) * 2018-09-22 2022-09-21 Parmar Sunjay Universal container holding device and procedure aid for spinal fluid sample collection
WO2021196412A1 (fr) * 2020-04-03 2021-10-07 南京汉欣医药科技有限公司 Vanne de régulation de débit pour réguler l'écoulement et le débit de liquide

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