WO2011056545A3 - Antimicrobial ionic liquids - Google Patents

Antimicrobial ionic liquids Download PDF

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Publication number
WO2011056545A3
WO2011056545A3 PCT/US2010/054048 US2010054048W WO2011056545A3 WO 2011056545 A3 WO2011056545 A3 WO 2011056545A3 US 2010054048 W US2010054048 W US 2010054048W WO 2011056545 A3 WO2011056545 A3 WO 2011056545A3
Authority
WO
WIPO (PCT)
Prior art keywords
ionic liquids
antimicrobial
antimicrobial ionic
species
pared
Prior art date
Application number
PCT/US2010/054048
Other languages
French (fr)
Other versions
WO2011056545A2 (en
Inventor
Mark W. Grinstaff
Michel Wathier
George A. O'toole
Original Assignee
Trustees Of Boston University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Trustees Of Boston University filed Critical Trustees Of Boston University
Publication of WO2011056545A2 publication Critical patent/WO2011056545A2/en
Publication of WO2011056545A3 publication Critical patent/WO2011056545A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4196—1,2,4-Triazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Medicinal Preparation (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Certain aspects of the present invention relate to compositions, formulations, and use of ionic liquids as antimicrobial agent (e.g. as antibacterial and/or antifungal agents). In certain embodiments, the ionic liquids can be pared with one or more singly charge species or with one or more multi-charged species.
PCT/US2010/054048 2009-10-26 2010-10-26 Antimicrobial ionic liquids WO2011056545A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25495709P 2009-10-26 2009-10-26
US61/254,957 2009-10-26

Publications (2)

Publication Number Publication Date
WO2011056545A2 WO2011056545A2 (en) 2011-05-12
WO2011056545A3 true WO2011056545A3 (en) 2011-09-22

Family

ID=43970658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/054048 WO2011056545A2 (en) 2009-10-26 2010-10-26 Antimicrobial ionic liquids

Country Status (1)

Country Link
WO (1) WO2011056545A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10449254B2 (en) 2013-11-03 2019-10-22 The Regents Of The University Of California Ionic liquids for transdermal drug delivery
CN109789216B (en) 2016-08-29 2023-05-23 加利福尼亚大学董事会 Topical skin treatment formulations based on ionic species
DK3528856T3 (en) 2016-10-18 2023-10-16 Univ Marquette Composite materials containing structural polymers and photoreactive nitrogen oxide releasing agents and uses thereof for wound dressings
US10828265B2 (en) 2016-12-09 2020-11-10 The Regents Of The University Of California Formulations of propranolol and analogs as an amorphous melt or ionic liquid for transdermal drug delivery
KR20200133183A (en) 2019-05-15 2020-11-26 더 홍콩 유니버시티 오브 사이언스 앤드 테크놀러지 Ionic liquid-based coating and method of making articles coated with the same
US11781106B1 (en) * 2021-03-01 2023-10-10 United States Of America As Represented By The Secretary Of The Air Force Intracellular non-genetic modification of microorganisms using protein ionic liquids
CN117717892B (en) * 2024-02-08 2024-04-30 四川益能康生环保科技有限公司 Composite desulfurizing agent for absorbing sulfur dioxide and preparation process thereof

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040077519A1 (en) * 2002-06-28 2004-04-22 The Procter & Gamble Co. Ionic liquid based products and method of using the same
US20070167332A1 (en) * 1999-09-07 2007-07-19 Akzo Nobel Surface Chemistry Llc Quaternary ammonium salts as thickening agents for aqueous systems
US20070225191A1 (en) * 2006-03-27 2007-09-27 The Procter & Gamble Company Methods for modifying bioplymers in ionic liquids
US20080070966A1 (en) * 2006-06-14 2008-03-20 Elder Stewart T Anti-microbial compositions

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070167332A1 (en) * 1999-09-07 2007-07-19 Akzo Nobel Surface Chemistry Llc Quaternary ammonium salts as thickening agents for aqueous systems
US20040077519A1 (en) * 2002-06-28 2004-04-22 The Procter & Gamble Co. Ionic liquid based products and method of using the same
US20070225191A1 (en) * 2006-03-27 2007-09-27 The Procter & Gamble Company Methods for modifying bioplymers in ionic liquids
US20080070966A1 (en) * 2006-06-14 2008-03-20 Elder Stewart T Anti-microbial compositions

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
KATHRYN M. DOCHERTY ET AL.: "Toxicity and antimicrobial activity of imidazolium and pyridinium ionic liquids", GREEN CHEMISTRY, vol. 7, 2005, pages 185 - 189 *

Also Published As

Publication number Publication date
WO2011056545A2 (en) 2011-05-12

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