WO2010148314A3 - Preparation of esomeprazole and its pharmaceutically acceptable salts - Google Patents

Preparation of esomeprazole and its pharmaceutically acceptable salts Download PDF

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Publication number
WO2010148314A3
WO2010148314A3 PCT/US2010/039187 US2010039187W WO2010148314A3 WO 2010148314 A3 WO2010148314 A3 WO 2010148314A3 US 2010039187 W US2010039187 W US 2010039187W WO 2010148314 A3 WO2010148314 A3 WO 2010148314A3
Authority
WO
WIPO (PCT)
Prior art keywords
esomeprazole
preparation
pharmaceutically acceptable
acceptable salts
processes
Prior art date
Application number
PCT/US2010/039187
Other languages
French (fr)
Other versions
WO2010148314A2 (en
Inventor
Srinivasa Reddy Bhimavarapu
Sree Naga Venkata Lakshmi Vara Prasad Vakamudi
Ravi Ram Chandra Sekhar Elati
Vijaya Bhaskar Bolugoddu
Original Assignee
Dr. Reddy's Laboratories Ltd.
Dr. Reddy's Laboratories, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr. Reddy's Laboratories Ltd., Dr. Reddy's Laboratories, Inc. filed Critical Dr. Reddy's Laboratories Ltd.
Publication of WO2010148314A2 publication Critical patent/WO2010148314A2/en
Publication of WO2010148314A3 publication Critical patent/WO2010148314A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Abstract

Processes for the preparation of esomeprazole and its pharmaceutically acceptable salts.
PCT/US2010/039187 2009-06-19 2010-06-18 Preparation of esomeprazole and its pharmaceutically acceptable salts WO2010148314A2 (en)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IN1452CH2009 2009-06-19
IN1452/CHE/2009 2009-06-19
US29261710P 2010-01-06 2010-01-06
US61/292,617 2010-01-06
IN573CH2010 2010-03-05
IN573/CHE/2010 2010-03-05

Publications (2)

Publication Number Publication Date
WO2010148314A2 WO2010148314A2 (en) 2010-12-23
WO2010148314A3 true WO2010148314A3 (en) 2011-05-26

Family

ID=43357070

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/039187 WO2010148314A2 (en) 2009-06-19 2010-06-18 Preparation of esomeprazole and its pharmaceutically acceptable salts

Country Status (1)

Country Link
WO (1) WO2010148314A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102993181B (en) * 2012-12-26 2014-07-23 山东大学 Preparation method of esomeprazole and preparation method of esomeprazole salt
CN104530003A (en) * 2014-06-10 2015-04-22 广东东阳光药业有限公司 Preparation method of salts of pyridylmethyl sulfinyl-1H-benzimidazole compounds
CN106366070B (en) * 2016-08-10 2019-06-11 上海万巷制药有限公司 A kind of preparation method of high-purity esomeprazole sodium
CN110305108B (en) * 2019-07-10 2022-05-03 湖南协创药品开发有限公司 Preparation method of esomeprazole magnesium
CN111072633A (en) * 2019-12-19 2020-04-28 山东达因海洋生物制药股份有限公司 Preparation method of esomeprazole magnesium trihydrate

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013743A1 (en) * 2005-07-28 2007-02-01 Hanmi Pharm. Co., Ltd. Method of preparing esomeprazole and salts thereof
EP1801110A1 (en) * 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
EP1847538A1 (en) * 2006-04-21 2007-10-24 Dipharma Francis S.r.l. A process for the preparation of pyridine compounds
US20090076277A1 (en) * 2006-10-30 2009-03-19 Dipharma Francis S.R.L. Process for the preparation of pyridine-methylsulfinyl compounds

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007013743A1 (en) * 2005-07-28 2007-02-01 Hanmi Pharm. Co., Ltd. Method of preparing esomeprazole and salts thereof
EP1801110A1 (en) * 2005-12-22 2007-06-27 KRKA, tovarna zdravil, d.d., Novo mesto Esomeprazole arginine salt
EP1847538A1 (en) * 2006-04-21 2007-10-24 Dipharma Francis S.r.l. A process for the preparation of pyridine compounds
US20090076277A1 (en) * 2006-10-30 2009-03-19 Dipharma Francis S.R.L. Process for the preparation of pyridine-methylsulfinyl compounds

Also Published As

Publication number Publication date
WO2010148314A2 (en) 2010-12-23

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