WO2010130974A3 - Sample cutter and production of tissue arrays - Google Patents

Sample cutter and production of tissue arrays Download PDF

Info

Publication number
WO2010130974A3
WO2010130974A3 PCT/GB2010/000921 GB2010000921W WO2010130974A3 WO 2010130974 A3 WO2010130974 A3 WO 2010130974A3 GB 2010000921 W GB2010000921 W GB 2010000921W WO 2010130974 A3 WO2010130974 A3 WO 2010130974A3
Authority
WO
WIPO (PCT)
Prior art keywords
cutter
production
sample cutter
tissue arrays
tissue
Prior art date
Application number
PCT/GB2010/000921
Other languages
French (fr)
Other versions
WO2010130974A2 (en
Inventor
Anne Fletcher
Colin Cooper
Original Assignee
The Institute Of Cancer Research: Royal Cancer Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Institute Of Cancer Research: Royal Cancer Hospital filed Critical The Institute Of Cancer Research: Royal Cancer Hospital
Publication of WO2010130974A2 publication Critical patent/WO2010130974A2/en
Publication of WO2010130974A3 publication Critical patent/WO2010130974A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

A cutter is provided for cutting samples from a tissue- containing body. The cutter comprises a blade holder and two blades extending from the holder. The blade holder is arranged to allow the operator of the cutter to view the sample when the cutter is located directly between the vantage point of the operator and the sample with the blades entering the tissue-containing body.
PCT/GB2010/000921 2009-05-12 2010-05-07 Sample cutter and production of tissue arrays WO2010130974A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB0908142A GB0908142D0 (en) 2009-05-12 2009-05-12 Sample cutter and production of tissue arrays
GB0908142.3 2009-05-12

Publications (2)

Publication Number Publication Date
WO2010130974A2 WO2010130974A2 (en) 2010-11-18
WO2010130974A3 true WO2010130974A3 (en) 2011-03-10

Family

ID=40833867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2010/000921 WO2010130974A2 (en) 2009-05-12 2010-05-07 Sample cutter and production of tissue arrays

Country Status (2)

Country Link
GB (1) GB0908142D0 (en)
WO (1) WO2010130974A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6417495B2 (en) 2016-10-07 2018-11-07 株式会社 ウミヒラ Tissue division jig
CN111562163A (en) * 2020-06-29 2020-08-21 台州市中心医院（台州学院附属医院） Method for manufacturing tissue chip through one-step molding and mold thereof
JPWO2023276768A1 (en) * 2021-06-29 2023-01-05

Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299758A (en) * 1964-11-12 1967-01-24 John R Mcculloch Microtome
US3673904A (en) * 1969-12-16 1972-07-04 N G N Ltd Microtome assemblies
US4021118A (en) * 1975-04-10 1977-05-03 Lkb-Produkter Ab Method in a microtome for approaching the knife to the specimen
EP0238190A2 (en) * 1986-02-12 1987-09-23 Beckman Research Institute of the City of Hope Multi-tumour tissue slices, methods for their production and testing the tissues in such slices
WO2000024940A1 (en) * 1998-10-28 2000-05-04 Vysis, Inc. Cellular arrays and methods of detecting and using genetic disorder markers
WO2001022086A1 (en) * 1999-09-24 2001-03-29 Jonathan Cohen A high-throughput system for evaluating the clinical utility of molecular targets in tissue samples
US20010003938A1 (en) * 1998-05-29 2001-06-21 Hans Heid Knife holder for a microtome
WO2003044213A2 (en) * 2001-11-20 2003-05-30 Genentech, Inc. Cell and tissue arrays and microarrays and methods of use
US20040030263A1 (en) * 2001-08-29 2004-02-12 Artemis Medical, Inc. Undamaged tissue collection assembly and method
US20040063221A1 (en) * 1997-10-16 2004-04-01 Millstein Larry S. Method for producing arrays and devices relating thereto
WO2006009733A2 (en) * 2004-06-18 2006-01-26 Covance, Inc. Frozen tissue microarray
WO2008069502A1 (en) * 2006-12-06 2008-06-12 Seung Min Song Mold of recipient block and usage thereof
US20080148913A1 (en) * 2006-12-21 2008-06-26 Industrial Technology Research Institute Dissecting device and method for cell and tissue
WO2008108410A1 (en) * 2007-03-07 2008-09-12 National University Corporation University Of Toyama Method of producing tissue array block, method of producing tissue array sheet, tissue array block, tissue array chip, system of producing tissue array block and system of producing tissue array sheet
US20080318805A1 (en) * 2007-06-08 2008-12-25 Regan Spencer Fulton Method and apparatus for producing high-yield tissue microarray blocks

Patent Citations (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3299758A (en) * 1964-11-12 1967-01-24 John R Mcculloch Microtome
US3673904A (en) * 1969-12-16 1972-07-04 N G N Ltd Microtome assemblies
US4021118A (en) * 1975-04-10 1977-05-03 Lkb-Produkter Ab Method in a microtome for approaching the knife to the specimen
EP0238190A2 (en) * 1986-02-12 1987-09-23 Beckman Research Institute of the City of Hope Multi-tumour tissue slices, methods for their production and testing the tissues in such slices
US20040063221A1 (en) * 1997-10-16 2004-04-01 Millstein Larry S. Method for producing arrays and devices relating thereto
US20010003938A1 (en) * 1998-05-29 2001-06-21 Hans Heid Knife holder for a microtome
WO2000024940A1 (en) * 1998-10-28 2000-05-04 Vysis, Inc. Cellular arrays and methods of detecting and using genetic disorder markers
WO2001022086A1 (en) * 1999-09-24 2001-03-29 Jonathan Cohen A high-throughput system for evaluating the clinical utility of molecular targets in tissue samples
US20040030263A1 (en) * 2001-08-29 2004-02-12 Artemis Medical, Inc. Undamaged tissue collection assembly and method
WO2003044213A2 (en) * 2001-11-20 2003-05-30 Genentech, Inc. Cell and tissue arrays and microarrays and methods of use
WO2006009733A2 (en) * 2004-06-18 2006-01-26 Covance, Inc. Frozen tissue microarray
WO2008069502A1 (en) * 2006-12-06 2008-06-12 Seung Min Song Mold of recipient block and usage thereof
US20080148913A1 (en) * 2006-12-21 2008-06-26 Industrial Technology Research Institute Dissecting device and method for cell and tissue
WO2008108410A1 (en) * 2007-03-07 2008-09-12 National University Corporation University Of Toyama Method of producing tissue array block, method of producing tissue array sheet, tissue array block, tissue array chip, system of producing tissue array block and system of producing tissue array sheet
US20080318805A1 (en) * 2007-06-08 2008-12-25 Regan Spencer Fulton Method and apparatus for producing high-yield tissue microarray blocks

Also Published As

Publication number Publication date
GB0908142D0 (en) 2009-06-24
WO2010130974A2 (en) 2010-11-18

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