WO2010098533A3 - Ecklonia cava extract with skin whitening activity - Google Patents

Ecklonia cava extract with skin whitening activity Download PDF

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Publication number
WO2010098533A3
WO2010098533A3 PCT/KR2009/006792 KR2009006792W WO2010098533A3 WO 2010098533 A3 WO2010098533 A3 WO 2010098533A3 KR 2009006792 W KR2009006792 W KR 2009006792W WO 2010098533 A3 WO2010098533 A3 WO 2010098533A3
Authority
WO
WIPO (PCT)
Prior art keywords
ecklonia cava
cava extract
skin whitening
whitening activity
activity
Prior art date
Application number
PCT/KR2009/006792
Other languages
French (fr)
Korean (ko)
Other versions
WO2010098533A2 (en
Inventor
윤나영
엄태길
김세권
Original Assignee
부경대학교 산학협력단
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 부경대학교 산학협력단 filed Critical 부경대학교 산학협력단
Publication of WO2010098533A2 publication Critical patent/WO2010098533A2/en
Publication of WO2010098533A3 publication Critical patent/WO2010098533A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9706—Algae
    • A61K8/9711—Phaeophycota or Phaeophyta [brown algae], e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A61K36/03—Phaeophycota or phaeophyta (brown algae), e.g. Fucus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
    • A61K2800/782—Enzyme inhibitors; Enzyme antagonists
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Botany (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cosmetics (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The present invention relates to an Ecklonia cava extract with skin whitening activity, more specifically to a pharmaceutical composition and a cosmetic composition for skin whitening containing Ecklonia cava extract which has an inhibition activity on tyrosinase and melanin biosynthesis, and a phlorotannin compound isolated from the same. According to the present invention, the Ecklonia cava extract and a component thereof, 7-phloroeckol, have a strong inhibition effect on mushroom tyrosinase. Especially, 7-phloroeckol has a significant inhibition effect on mushroom tyrosinase and melanogenesis in melanoma cells.
PCT/KR2009/006792 2009-02-26 2009-11-18 Ecklonia cava extract with skin whitening activity WO2010098533A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2009-0016167 2009-02-26
KR1020090016167A KR101016761B1 (en) 2009-02-26 2009-02-26 Ecklonia cava Kjellman extracts having skin whitening activity

Publications (2)

Publication Number Publication Date
WO2010098533A2 WO2010098533A2 (en) 2010-09-02
WO2010098533A3 true WO2010098533A3 (en) 2010-10-21

Family

ID=42666016

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/006792 WO2010098533A2 (en) 2009-02-26 2009-11-18 Ecklonia cava extract with skin whitening activity

Country Status (2)

Country Link
KR (1) KR101016761B1 (en)
WO (1) WO2010098533A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103338780A (en) * 2010-12-20 2013-10-02 韩国食品研究院 Composition for positively allosterically modulating GABAA-benzodiazepine receptor and composition for producing sedative-hypnotic effects containing ecklonia cava extract and ecklonia kurome extract
KR101313724B1 (en) * 2011-10-07 2013-10-02 부경대학교 산학협력단 The hair growth solution mainly comprised of Ecklonia cava extract, and the hair treatment composition
DK3064572T3 (en) 2013-11-01 2020-05-04 Bbhc Co Ltd PROCEDURE FOR MANUFACTURING INDUCED PLURIPOTENT STEM CELLS FROM MESENCHYMAL STEM CELLS AND INDUCED PLURIPOTENT STEM CELLS PRODUCED BY THE PROCEDURE
KR101542846B1 (en) 2013-11-01 2015-08-10 주식회사 비비에이치씨 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Chondrocyte
KR101542847B1 (en) 2013-11-01 2015-08-10 주식회사 비비에이치씨 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Neuron
KR101542849B1 (en) 2013-11-01 2015-08-10 주식회사 비비에이치씨 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Hepatocyte
KR101542850B1 (en) 2013-11-01 2015-08-10 주식회사 비비에이치씨 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Adipocyte
KR101542848B1 (en) 2013-11-01 2015-08-10 주식회사 비비에이치씨 Method for Differentiating Pluripotency Stem Cell Induced from Mesenchymal Stem Cell into Osteoblast
KR102154052B1 (en) * 2017-10-26 2020-09-10 주식회사 보타메디 Compositions containing phlorotannin for cooling skin and product thereof
KR102011654B1 (en) * 2017-12-07 2019-08-19 주식회사 선마린바이오테크 Cosmetic composition comprising oysters, sea cucumber, sea squirt, Aplysia kurodai and buccinum striatissimum
KR102113183B1 (en) 2018-09-10 2020-05-21 순천향대학교 산학협력단 Extracts Of Seaweeds Of The Genus Escherichia Immersed In Magma Seawater And Method Thereof
WO2022171292A1 (en) 2021-02-12 2022-08-18 Symrise Ag Medicament for prevention and treatment of hyperpigmentation

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04235110A (en) * 1991-01-11 1992-08-24 T Ee C Gijutsu Kagaku Kenkyusho:Kk Tyrosinase-inhibitor
KR100359996B1 (en) * 2000-08-23 2002-11-07 벤트리 주식회사 Whitening cosmetics containing extracts from Ecklonia cava

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04235110A (en) * 1991-01-11 1992-08-24 T Ee C Gijutsu Kagaku Kenkyusho:Kk Tyrosinase-inhibitor
KR100359996B1 (en) * 2000-08-23 2002-11-07 벤트리 주식회사 Whitening cosmetics containing extracts from Ecklonia cava

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEE, HYUN JIN ET AL.: "Prolyl Endopeptidase, Inhibitory Activities of Sea Weeds on Prolyl Endopeptidase, Tyrosinase and Coagulation", THE KOREAN SOCIETY OF PHARMACOGNOSY, vol. 30, no. 3, 1999, pages 231 - 237, XP053013554 *
YOON, N. -Y. ET AL.: "Inhibitory Effect of Phlorotannins Isolated from Ecklonia cava on Mushroom Tyrosinase Activity and Melanin Formation in Mouse B 16F 10 Melanoma Cells", J. AGRIC. FOOD. CHEM., vol. 57, 10 April 2009 (2009-04-10), pages 4124 - 4129 *

Also Published As

Publication number Publication date
KR101016761B1 (en) 2011-02-25
KR20100097293A (en) 2010-09-03
WO2010098533A2 (en) 2010-09-02

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