WO2010066921A3 - Device and method for the dynamic study of biofilms on catheters for medical use - Google Patents

Device and method for the dynamic study of biofilms on catheters for medical use Download PDF

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Publication number
WO2010066921A3
WO2010066921A3 PCT/ES2009/000566 ES2009000566W WO2010066921A3 WO 2010066921 A3 WO2010066921 A3 WO 2010066921A3 ES 2009000566 W ES2009000566 W ES 2009000566W WO 2010066921 A3 WO2010066921 A3 WO 2010066921A3
Authority
WO
WIPO (PCT)
Prior art keywords
catheters
samples
biofilms
medical use
dynamic study
Prior art date
Application number
PCT/ES2009/000566
Other languages
Spanish (es)
French (fr)
Other versions
WO2010066921A2 (en
Inventor
Antonio Ojeda Monge
Jorge LÓPEZ SERRANO
Isabel GARCÍA LUQUE
Carmen Conejo Gonzalo
Jesús RODRÍGUEZ BAÑO
Álvaro PASCUAL HERNÁNDEZ
Original Assignee
Universidad De Sevilla
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universidad De Sevilla filed Critical Universidad De Sevilla
Publication of WO2010066921A2 publication Critical patent/WO2010066921A2/en
Publication of WO2010066921A3 publication Critical patent/WO2010066921A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/02—Membranes; Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Clinical Laboratory Science (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Cell Biology (AREA)
  • Virology (AREA)
  • Hematology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to a device and method for the dynamic study of biofilms on catheters for medical use. The device enables the introduction of multiple samples which can be evaluated simultaneously and, consequently, a number of biomaterials can be analysed in a single experiment. The liquid flows over all of the samples parallel to the axis of the catheter segment, thereby correctly recreating the real flow that occurs when the catheters are implanted. The samples are extracted on an individual basis, thereby preventing the remaining samples from being exposed to the atmosphere and reducing the risk of interferences in the analysis or contamination of the system.
PCT/ES2009/000566 2008-12-11 2009-12-11 Device and method for the dynamic study of biofilms on catheters for medical use WO2010066921A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200803508A ES2354781B2 (en) 2008-12-11 2008-12-11 DEVICE AND METHOD FOR THE DYNAMIC STUDY OF BIOCAPAS ON MEDICAL CATHETERS.
ESP200803508 2008-12-11

Publications (2)

Publication Number Publication Date
WO2010066921A2 WO2010066921A2 (en) 2010-06-17
WO2010066921A3 true WO2010066921A3 (en) 2010-08-05

Family

ID=42243123

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2009/000566 WO2010066921A2 (en) 2008-12-11 2009-12-11 Device and method for the dynamic study of biofilms on catheters for medical use

Country Status (2)

Country Link
ES (1) ES2354781B2 (en)
WO (1) WO2010066921A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6361963B1 (en) * 2000-08-02 2002-03-26 Hercules Incorporated Biofilm growth device
US6596505B2 (en) * 2000-04-17 2003-07-22 University Technologies International, Inc. Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms
WO2006063176A2 (en) * 2004-12-06 2006-06-15 The Government Of The Usa As Representedtd By The Secretary Of The Dept Of Health And Human Services Inhibition of biofilm formation using bacteriophage
US20060166358A1 (en) * 1997-03-12 2006-07-27 University Technologies International, Inc. Biofilm incubation

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060166358A1 (en) * 1997-03-12 2006-07-27 University Technologies International, Inc. Biofilm incubation
US6596505B2 (en) * 2000-04-17 2003-07-22 University Technologies International, Inc. Apparatus and methods for testing effects of materials and surface coatings on the formation of biofilms
US6361963B1 (en) * 2000-08-02 2002-03-26 Hercules Incorporated Biofilm growth device
WO2006063176A2 (en) * 2004-12-06 2006-06-15 The Government Of The Usa As Representedtd By The Secretary Of The Dept Of Health And Human Services Inhibition of biofilm formation using bacteriophage

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
EVANS ET AL.: "In vitro modeling of a biomaterial associated Staphylococcal biofilm", ADVANCES IN PERITONEAL DIALYSIS., vol. 3, 1987, pages 93 *

Also Published As

Publication number Publication date
WO2010066921A2 (en) 2010-06-17
ES2354781B2 (en) 2011-07-12
ES2354781A1 (en) 2011-03-18

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