WO2010055474A3 - Antimicrobial compounds and compositions - Google Patents

Antimicrobial compounds and compositions Download PDF

Info

Publication number
WO2010055474A3
WO2010055474A3 PCT/IB2009/055016 IB2009055016W WO2010055474A3 WO 2010055474 A3 WO2010055474 A3 WO 2010055474A3 IB 2009055016 W IB2009055016 W IB 2009055016W WO 2010055474 A3 WO2010055474 A3 WO 2010055474A3
Authority
WO
WIPO (PCT)
Prior art keywords
compositions
antimicrobial compounds
compounds
microbes
infection
Prior art date
Application number
PCT/IB2009/055016
Other languages
French (fr)
Other versions
WO2010055474A2 (en
Inventor
Gary Gellerman
Oded Yarden
Alex Aizikovich
Original Assignee
Ariel-University Research And Development Company Ltd.
Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ariel-University Research And Development Company Ltd., Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. filed Critical Ariel-University Research And Development Company Ltd.
Publication of WO2010055474A2 publication Critical patent/WO2010055474A2/en
Publication of WO2010055474A3 publication Critical patent/WO2010055474A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
    • A01N47/08—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having one or more single bonds to nitrogen atoms
    • A01N47/10—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof
    • A01N47/18—Carbamic acid derivatives, i.e. containing the group —O—CO—N<; Thio analogues thereof containing a —O—CO—N< group, or a thio analogue thereof, directly attached to a heterocyclic or cycloaliphatic ring
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N35/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical
    • A01N35/04—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having two bonds to hetero atoms with at the most one bond to halogen, e.g. aldehyde radical containing aldehyde or keto groups, or thio analogues thereof, directly attached to an aromatic ring system, e.g. acetophenone; Derivatives thereof, e.g. acetals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
    • A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
    • A23L3/3454—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals in the form of liquids or solids
    • A23L3/3463—Organic compounds; Microorganisms; Enzymes
    • A23L3/3526—Organic compounds containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Abstract

Disclosed are antimicrobial compounds and compositions, the use of such compounds and compositions in the treatment of an infection by microbes and methods for treating an infection by microbes, for example of fungi and oomycetes.
PCT/IB2009/055016 2008-11-13 2009-11-11 Antimicrobial compounds and compositions WO2010055474A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19327808P 2008-11-13 2008-11-13
US61/193,278 2008-11-13

Publications (2)

Publication Number Publication Date
WO2010055474A2 WO2010055474A2 (en) 2010-05-20
WO2010055474A3 true WO2010055474A3 (en) 2010-12-16

Family

ID=41818587

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/055016 WO2010055474A2 (en) 2008-11-13 2009-11-11 Antimicrobial compounds and compositions

Country Status (1)

Country Link
WO (1) WO2010055474A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2774481T3 (en) 2013-03-08 2019-03-29 Symrise Ag Antimicrobial compositions
US9090546B1 (en) * 2014-07-03 2015-07-28 Coorstek Fluorochemicals, Inc. Fluoronation of alpha-haloalkyl ketones
US9643907B2 (en) 2014-07-03 2017-05-09 Coorstek Fluorochemicals, Inc. Fluoronation of alpha-haloalkyl ketones
CN109112069B (en) * 2017-06-23 2021-09-24 沈阳药科大学 Biocontrol endophytic fungus and application thereof
AU2019434303A1 (en) 2019-03-12 2021-09-23 Symrise Ag An antimicrobial mixture

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085673A1 (en) * 2000-05-08 2001-11-15 Bayer Cropscience Ag Phenyl-substituted 2-enamino-keto nitriles
WO2007100295A1 (en) * 2006-03-03 2007-09-07 Torrent Pharmaceuticals Ltd Novel dual action receptors antagonists (dara) at the ati and eta receptors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001085673A1 (en) * 2000-05-08 2001-11-15 Bayer Cropscience Ag Phenyl-substituted 2-enamino-keto nitriles
WO2007100295A1 (en) * 2006-03-03 2007-09-07 Torrent Pharmaceuticals Ltd Novel dual action receptors antagonists (dara) at the ati and eta receptors

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; July 2006 (2006-07-01), NGARMSAK MANATCHAYA ET AL: "Antimicrobial activity of vanillin against spoilage microorganisms in stored fresh-cut mangoes.", XP002590893, Database accession no. NLM16865911 *
DATABASE MEDLINE [online] US NATIONAL LIBRARY OF MEDICINE (NLM), BETHESDA, MD, US; May 1999 (1999-05-01), MATAMOROS-LEÓN B ET AL: "Individual and combined effects of vanillin and potassium sorbate on Penicillium digitatum, Penicillium glabrum, and Penicillium italicum growth.", XP002590892, Database accession no. NLM10340678 *
GELLERMAN, GARY ET AL: "Synthesis and antifungal activity of .beta.-trifluoroalkyl aminovinyl ketone derivatives", JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, CODEN: JAFCAU, vol. 57, no. 18, 2009, pages 8303 - 8307, XP002590894, ISSN: 0021-8561 *
HORSFALL, JAMES G. ET AL: "The effect of synthetic compounds on sporulation of Monilinia fructicola", TRANSACTIONS OF THE NEW YORK ACADEMY OF SCIENCES, CODEN: TNYAAE, vol. 18, 1955, pages 69 - 80, XP002590890, ISSN: 0028-7113 *
JOURNAL OF FOOD PROTECTION JUL 2006 LNKD- PUBMED:16865911, vol. 69, no. 7, July 2006 (2006-07-01), pages 1724 - 1727, ISSN: 0362-028X *
JOURNAL OF FOOD PROTECTION MAY 1999 LNKD- PUBMED:10340678, vol. 62, no. 5, May 1999 (1999-05-01), pages 540 - 542, ISSN: 0362-028X *
SOSNOVSKIKH, V. YA. ET AL: "Reactions of aromatic and heteroaromatic .beta.-amino-.beta.-(polyfluoroalkyl)vinyl ketones with ethylenediamine. A new synthesis of N,N'-unsubstituted imidazolidines", RUSSIAN CHEMICAL BULLETIN (TRANSLATION OF IZVESTIYA AKADEMII NAUK, SERIYA KHIMICHESKAYA), CODEN: RCBUEY, vol. 48, no. 3, 1999, pages 540 - 551, XP002590891, ISSN: 1066-5285 *

Also Published As

Publication number Publication date
WO2010055474A2 (en) 2010-05-20

Similar Documents

Publication Publication Date Title
PH12016502092A1 (en) Antimicrobial compounds and methods of making and using the same
WO2011047323A3 (en) Antimicrobial compounds and methods of making and using the same
WO2010090860A3 (en) Methods and compositions for treating bacterial infection
WO2008060374A3 (en) Methods and compositions useful for diabetic wound healing
WO2007130655A3 (en) Phage derived antimicrobial activities
WO2012020214A3 (en) Anti-microbial metal organic framework
MX2009008617A (en) Use of il-23 antagonists for treatment of infection.
WO2012173689A3 (en) Antimicrobial compounds and methods of making and using the same
WO2011030158A3 (en) Antimicrobial composition
WO2007085852A3 (en) Antimicrobial materials
WO2011071904A3 (en) Inhibiting bacterial infection and biofilm formation
WO2010032011A8 (en) Anti-fungal therapy
WO2011091322A3 (en) Antimicrobial agent comprising peroxide, alcohol and chelating agent
PH12015502375B1 (en) Antimicrobial compounds and methods of making and using the same
MX2012000136A (en) Compositions comprising finafloxacin and methods for treating ophthalmic, otic, or nasal infections.
WO2013120022A3 (en) Treatment of hypoglycemia
WO2009009034A3 (en) Methods and compositions useful in the treatment of mucositis
WO2012017321A3 (en) Treatment for dyslipidemia
WO2010134827A9 (en) Extended acting oxygen generating composition for treating microbial infections
MY165011A (en) Antimicrobial compounds and methods of making and using the same
WO2010055474A3 (en) Antimicrobial compounds and compositions
WO2013166282A3 (en) Methods and compositions for treating bacterial infection
WO2010123599A3 (en) Anti-bacterial compositions and methods including targeting virulence factors of staphylococcus aureus
EP2597949A4 (en) Sub-micron compositions
WO2015035234A3 (en) Anti-microbial compounds and compositions

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09764298

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09764298

Country of ref document: EP

Kind code of ref document: A2