WO2010023690A3 - Prolonged release formulation of amisulpride - Google Patents

Prolonged release formulation of amisulpride Download PDF

Info

Publication number
WO2010023690A3
WO2010023690A3 PCT/IN2009/000471 IN2009000471W WO2010023690A3 WO 2010023690 A3 WO2010023690 A3 WO 2010023690A3 IN 2009000471 W IN2009000471 W IN 2009000471W WO 2010023690 A3 WO2010023690 A3 WO 2010023690A3
Authority
WO
WIPO (PCT)
Prior art keywords
amisulpride
prolonged release
release formulation
relates
dosage form
Prior art date
Application number
PCT/IN2009/000471
Other languages
French (fr)
Other versions
WO2010023690A2 (en
Inventor
Jaya Abraham
Original Assignee
Torrent Pharmaceuticals Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Torrent Pharmaceuticals Ltd. filed Critical Torrent Pharmaceuticals Ltd.
Publication of WO2010023690A2 publication Critical patent/WO2010023690A2/en
Publication of WO2010023690A3 publication Critical patent/WO2010023690A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to a prolonged release dosage form comprising amisulpride preferably in the form of a multiunit pellets or micro tablets filled into capsule or compressed in to tablet or bilayered tablet. It also relates to the process for preparing the said dosage form.
PCT/IN2009/000471 2008-08-28 2009-08-28 Prolonged release formulation of amisulpride WO2010023690A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1807/MUM/2008 2008-08-28
IN1807MU2008 2008-08-28

Publications (2)

Publication Number Publication Date
WO2010023690A2 WO2010023690A2 (en) 2010-03-04
WO2010023690A3 true WO2010023690A3 (en) 2010-06-03

Family

ID=41722052

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2009/000471 WO2010023690A2 (en) 2008-08-28 2009-08-28 Prolonged release formulation of amisulpride

Country Status (1)

Country Link
WO (1) WO2010023690A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2018378348A1 (en) 2017-12-05 2020-06-18 Sunovion Pharmaceuticals Inc. Crystal forms and production methods thereof
WO2019113079A1 (en) 2017-12-05 2019-06-13 Sunovion Pharmaceuticals Inc. Nonracemic mixtures and uses thereof
CN109010300A (en) * 2018-10-24 2018-12-18 湖南洞庭药业股份有限公司 A kind of Amisulpride piece and preparation method thereof
US20220323409A1 (en) * 2019-06-04 2022-10-13 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
CA3142355A1 (en) * 2019-06-04 2020-12-10 Sunovion Pharmaceuticals Inc. Modified release formulations and uses thereof
CN115487161B (en) * 2022-11-18 2023-03-03 山东则正医药技术有限公司 Preparation method of amisulpride tablets

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62178518A (en) * 1986-01-30 1987-08-05 Toho Yakuhin Kogyo Kk Novel long-acting sulpiride tablet
US20010046473A1 (en) * 1997-04-18 2001-11-29 Jerome Besse Gastric-retained pharmaceutical composition and method for its use
US20060153925A1 (en) * 2003-07-09 2006-07-13 Sanofi-Aventis Novel solid pharmaceutical composition comprising amisulpride
US20080188537A1 (en) * 2007-02-02 2008-08-07 Jean-Michel Azorin Method of treating bipolar depression with a benzamide derivative

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62178518A (en) * 1986-01-30 1987-08-05 Toho Yakuhin Kogyo Kk Novel long-acting sulpiride tablet
US20010046473A1 (en) * 1997-04-18 2001-11-29 Jerome Besse Gastric-retained pharmaceutical composition and method for its use
US20060153925A1 (en) * 2003-07-09 2006-07-13 Sanofi-Aventis Novel solid pharmaceutical composition comprising amisulpride
US20080188537A1 (en) * 2007-02-02 2008-08-07 Jean-Michel Azorin Method of treating bipolar depression with a benzamide derivative

Also Published As

Publication number Publication date
WO2010023690A2 (en) 2010-03-04

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