WO2010015586A3 - 2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds - Google Patents
2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds Download PDFInfo
- Publication number
- WO2010015586A3 WO2010015586A3 PCT/EP2009/059999 EP2009059999W WO2010015586A3 WO 2010015586 A3 WO2010015586 A3 WO 2010015586A3 EP 2009059999 W EP2009059999 W EP 2009059999W WO 2010015586 A3 WO2010015586 A3 WO 2010015586A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- indolo
- tetrahydro
- quinoline compounds
- invention pertains
- present
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Abstract
The present invention pertains to 2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds, as well as the resulting pharmaceutical compositions, and their use in the treatment or prophylaxis of diseases alleviated by inhibition of type 5 phosphodiesterases. Furthermore, the present invention pertains to the methods of manufacturing these 2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP08161789 | 2008-08-05 | ||
EP08161789.6 | 2008-08-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2010015586A2 WO2010015586A2 (en) | 2010-02-11 |
WO2010015586A3 true WO2010015586A3 (en) | 2010-07-22 |
Family
ID=40029596
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2009/059999 WO2010015586A2 (en) | 2008-08-05 | 2009-08-03 | 2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2010015586A2 (en) |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014883A (en) * | 1973-09-10 | 1977-03-29 | Hoffmann-La Roche Inc. | Indoloquinolines, intermediates and processes |
SU753093A1 (en) * | 1979-03-05 | 1982-11-30 | Институт физико-органической химии и углехимии АН УССР | 1-methyl-3,4-(delta 2,2-dimethyl-4-oxotetrahydrobenzo)-tranquilizing activity |
WO2002064590A2 (en) * | 2001-02-12 | 2002-08-22 | Lilly Icos Llc | Carboline derivatives |
US20080051426A1 (en) * | 2006-08-28 | 2008-02-28 | Irina Shcherbakova | Indoloquinoline compounds as calcium channel blockers |
EP1953159A1 (en) * | 2007-02-05 | 2008-08-06 | Nycomed GmbH | 6-Benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds useful as PDE5 inhibitors |
-
2009
- 2009-08-03 WO PCT/EP2009/059999 patent/WO2010015586A2/en active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4014883A (en) * | 1973-09-10 | 1977-03-29 | Hoffmann-La Roche Inc. | Indoloquinolines, intermediates and processes |
SU753093A1 (en) * | 1979-03-05 | 1982-11-30 | Институт физико-органической химии и углехимии АН УССР | 1-methyl-3,4-(delta 2,2-dimethyl-4-oxotetrahydrobenzo)-tranquilizing activity |
WO2002064590A2 (en) * | 2001-02-12 | 2002-08-22 | Lilly Icos Llc | Carboline derivatives |
US20080051426A1 (en) * | 2006-08-28 | 2008-02-28 | Irina Shcherbakova | Indoloquinoline compounds as calcium channel blockers |
WO2008027182A2 (en) * | 2006-08-28 | 2008-03-06 | Medipropharma, Inc. | Indoloquinoline compounds as calcium channel blockers |
EP1953159A1 (en) * | 2007-02-05 | 2008-08-06 | Nycomed GmbH | 6-Benzyl-2,3,4,7-tetrahydro-indolo[2,3-c]quinoline compounds useful as PDE5 inhibitors |
Also Published As
Publication number | Publication date |
---|---|
WO2010015586A2 (en) | 2010-02-11 |
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