WO2009158719A3 - Methods and compositions for treating disorders - Google Patents
Methods and compositions for treating disorders Download PDFInfo
- Publication number
- WO2009158719A3 WO2009158719A3 PCT/US2009/049106 US2009049106W WO2009158719A3 WO 2009158719 A3 WO2009158719 A3 WO 2009158719A3 US 2009049106 W US2009049106 W US 2009049106W WO 2009158719 A3 WO2009158719 A3 WO 2009158719A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compositions
- methods
- treating disorders
- treating
- disorders
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Compounds and compositions for treating TRPA1 mediated disorders are described herein.
Applications Claiming Priority (14)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7630908P | 2008-06-27 | 2008-06-27 | |
US7644108P | 2008-06-27 | 2008-06-27 | |
US7640608P | 2008-06-27 | 2008-06-27 | |
US7641108P | 2008-06-27 | 2008-06-27 | |
US7644408P | 2008-06-27 | 2008-06-27 | |
US7640208P | 2008-06-27 | 2008-06-27 | |
US7640908P | 2008-06-27 | 2008-06-27 | |
US61/076,441 | 2008-06-27 | ||
US61/076,444 | 2008-06-27 | ||
US61/076,406 | 2008-06-27 | ||
US61/076,309 | 2008-06-27 | ||
US61/076,411 | 2008-06-27 | ||
US61/076,409 | 2008-06-27 | ||
US61/076,402 | 2008-06-27 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009158719A2 WO2009158719A2 (en) | 2009-12-30 |
WO2009158719A3 true WO2009158719A3 (en) | 2010-04-29 |
Family
ID=41445391
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2009/049106 WO2009158719A2 (en) | 2008-06-27 | 2009-06-29 | Methods and compositions for treating disorders |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009158719A2 (en) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK2411397T3 (en) | 2009-03-23 | 2013-08-05 | Glenmark Pharmaceuticals Sa | Isothiazole-pyrimidinedione derivatives as modulators of TRPA1 |
CN102361874A (en) | 2009-03-23 | 2012-02-22 | 格兰马克药品股份有限公司 | Furopyrimidinedione derivatives as trpa1 modulators |
MX2011009824A (en) | 2009-03-23 | 2012-01-25 | Glenmark Pharmaceuticals Sa | Fused pyrimidine-dione derivatives as trpa1 modulators. |
US8623880B2 (en) | 2009-03-23 | 2014-01-07 | Glenmark Pharmaceuticals S.A. | Fused pyrimidine-dione derivatives as TRPA1 modulators |
CN103261201B (en) | 2010-12-20 | 2015-04-22 | 格兰马克药品股份有限公司 | 2-amino-4-arylthiazole compounds as TRPA1 antagonists |
BR112013032025A2 (en) | 2011-06-13 | 2016-12-20 | Glenmark Pharmaceutical S A | trpa1 antagonists, compounds or their pharmaceutically acceptable salts, methods for reducing the amount of eosinophils or neutrophils and / or increasing fev1 in an individual with respiratory disorder, for treating respiratory disorder in an individual and / or for identifying trpa1 antagonist, effective amount of antagonist uses trpa1, and pharmaceutical composition for inhalation administration |
WO2012176105A1 (en) | 2011-06-22 | 2012-12-27 | Glenmark Pharmaceuticals Sa | Pharmaceutical composition comprising a trpa1 antagonist and a leukotriene receptor antagonist |
JP2014517062A (en) | 2011-06-22 | 2014-07-17 | グレンマーク ファーマシューティカルズ, エセ.アー. | Pharmaceutical composition comprising a TRPA1 antagonist and a β2 agonist |
WO2013014597A1 (en) | 2011-07-25 | 2013-01-31 | Glenmark Pharmaceuticals Sa | Pharmaceutical composition comprising a trpa1 antagonist and a steroid |
CA2857109A1 (en) | 2011-12-05 | 2013-06-13 | Glenmark Pharmaceuticals S.A. | Pharmaceutical composition comprising a trpa1 antagonist and an anticholinergic agent |
MX354014B (en) | 2012-06-08 | 2018-02-08 | Glenmark Pharmaceuticals Sa | Amides of 2-amino-4-arylthiazole compounds and their salts. |
CA2926389A1 (en) | 2013-10-15 | 2015-04-23 | Glenmark Pharmaceuticals S.A. | Pharmaceutical composition comprising a trpa1 antagonist and an analgesic agent |
US20190175599A1 (en) | 2014-09-16 | 2019-06-13 | Glemark Pharmaceuticals S.A. | Trpa1 antagonist for the treatment of pain associated to diabetic neuropathic pain |
WO2017060488A1 (en) | 2015-10-09 | 2017-04-13 | Almirall, S.A. | New trpa1 antagonists |
WO2017064068A1 (en) | 2015-10-14 | 2017-04-20 | Almirall, S.A. | New trpa1 antagonists |
JP2023529867A (en) | 2020-06-05 | 2023-07-12 | キネート バイオファーマ インク. | Inhibitor of fibroblast growth factor receptor kinase |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005089206A2 (en) * | 2004-03-13 | 2005-09-29 | Irm Llc | Modulators of ion channel trpa1 |
WO2007073505A2 (en) * | 2005-12-22 | 2007-06-28 | Hydra Biosciences, Inc. | Trpa1 inhibitors for treating pain |
-
2009
- 2009-06-29 WO PCT/US2009/049106 patent/WO2009158719A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005089206A2 (en) * | 2004-03-13 | 2005-09-29 | Irm Llc | Modulators of ion channel trpa1 |
WO2007073505A2 (en) * | 2005-12-22 | 2007-06-28 | Hydra Biosciences, Inc. | Trpa1 inhibitors for treating pain |
US20070219222A1 (en) * | 2005-12-22 | 2007-09-20 | Hydra Biosciences | Methods and compositions for treating pain |
Non-Patent Citations (1)
Title |
---|
MATT PATRUS ET AL.: "A role of TRPAI in mechanical hyperalgesia is revealed by pharmacological inhibition", MOLECULAR PAIN, vol. 3, no. 40, 17 December 2007 (2007-12-17), pages 1 - 8 * |
Also Published As
Publication number | Publication date |
---|---|
WO2009158719A2 (en) | 2009-12-30 |
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