WO2009150632A3 - Apparatus for preparing controlled amounts of liquid for cytometry - Google Patents

Apparatus for preparing controlled amounts of liquid for cytometry Download PDF

Info

Publication number
WO2009150632A3
WO2009150632A3 PCT/IB2009/052518 IB2009052518W WO2009150632A3 WO 2009150632 A3 WO2009150632 A3 WO 2009150632A3 IB 2009052518 W IB2009052518 W IB 2009052518W WO 2009150632 A3 WO2009150632 A3 WO 2009150632A3
Authority
WO
WIPO (PCT)
Prior art keywords
liquid
tubes
moving
controlled amounts
sampler
Prior art date
Application number
PCT/IB2009/052518
Other languages
French (fr)
Other versions
WO2009150632A2 (en
Inventor
Giovanni Marchini
Original Assignee
Hta S.R.L.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hta S.R.L. filed Critical Hta S.R.L.
Publication of WO2009150632A2 publication Critical patent/WO2009150632A2/en
Publication of WO2009150632A3 publication Critical patent/WO2009150632A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B5/00—Other centrifuges
    • B04B5/04—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers
    • B04B5/0407—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles
    • B04B5/0414—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes
    • B04B5/0421—Radial chamber apparatus for separating predominantly liquid mixtures, e.g. butyrometers for liquids contained in receptacles comprising test tubes pivotably mounted
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B11/00—Feeding, charging, or discharging bowls
    • B04B11/04—Periodical feeding or discharging; Control arrangements therefor
    • B04B2011/046—Loading, unloading, manipulating sample containers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00465—Separating and mixing arrangements
    • G01N2035/00495—Centrifuges
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04—Details of the conveyor system
    • G01N2035/0439—Rotary sample carriers, i.e. carousels
    • G01N2035/0441—Rotary sample carriers, i.e. carousels for samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027—General features of the devices
    • G01N2035/1048—General features of the devices using the transfer device for another function
    • G01N2035/1051—General features of the devices using the transfer device for another function for transporting containers, e.g. retained by friction
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1081—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane
    • G01N35/1083—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices characterised by the means for relatively moving the transfer device and the containers in an horizontal plane with one horizontal degree of freedom
    • G01N2035/1086—Cylindrical, e.g. variable angle
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0099—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor comprising robots or similar manipulators

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

An apparatus for preparing controlled amounts of liquid for cytometry, which comprises a sampler (2) having: motion imparting means (3) for moving a main tray (4) with one or more tubes thereon, each containing a controlled amount of liquid; a support and moving unit (6) for supporting and moving a syringe (7) that transfers preparation liquids into the tubes (5); a motion imparting mechanism (8) for moving the piston of the syringe (7). The apparatus (1) comprises a centrifuge (10) located beside the sampler (2) and having an access opening (11) for receiving the tubes (5), for selective removal of residues to be discarded from the controlled amounts of liquid. Furthermore, the sampler (2) comprises a motorized gripping mechanism (12) disposed in the support and moving unit (6) and coaxial with the syringe (7), the support and moving unit (6) being movable to allow the tubes (5) to be carried from the main tray (4) to the centrifuge (10) and vice versa.
PCT/IB2009/052518 2008-06-13 2009-06-12 Apparatus for preparing controlled amounts of liquid for cytometry WO2009150632A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SM200800035A SM200800035B (en) 2008-06-13 2008-06-13 Preparatory apparatus of controlled quantities of liquid for cytometry
SMSM-A-200800035 2008-06-13

Publications (2)

Publication Number Publication Date
WO2009150632A2 WO2009150632A2 (en) 2009-12-17
WO2009150632A3 true WO2009150632A3 (en) 2010-02-04

Family

ID=41278414

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/052518 WO2009150632A2 (en) 2008-06-13 2009-06-12 Apparatus for preparing controlled amounts of liquid for cytometry

Country Status (2)

Country Link
SM (1) SM200800035B (en)
WO (1) WO2009150632A2 (en)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8840848B2 (en) 2010-07-23 2014-09-23 Beckman Coulter, Inc. System and method including analytical units
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system
US9046506B2 (en) 2011-11-07 2015-06-02 Beckman Coulter, Inc. Specimen container detection
US9446418B2 (en) 2011-11-07 2016-09-20 Beckman Coulter, Inc. Robotic arm
US9482684B2 (en) 2011-11-07 2016-11-01 Beckman Coulter, Inc. Centrifuge system and workflow
US9506943B2 (en) 2011-11-07 2016-11-29 Beckman Coulter, Inc. Aliquotter system and workflow

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU228711B1 (en) * 2011-08-22 2013-05-28 Diagon Kft Method and apparatus for feeding cuvetta comprising assay and reagent
CN104053997B (en) 2011-11-07 2016-12-21 贝克曼考尔特公司 For processing the system and method for sample
HU229210B1 (en) * 2011-11-16 2013-09-30 Diagon Kft Method and automatic device for in vitro diagnostic tests of blood clotting
EP2817606B1 (en) 2012-02-24 2021-06-02 Instrunor AS Instrument for pretreating cell samples
CN105004872B (en) * 2015-07-19 2017-03-08 武汉明德生物科技股份有限公司 Full-automatic immunity quantitative analyzer
CN105067825B (en) * 2015-07-19 2017-05-31 武汉明德生物科技股份有限公司 A exempt from to pull out lid sampling assembly for full-automatic immunity quantitative analysis appearance
CN105004873B (en) * 2015-07-19 2017-03-01 武汉明德生物科技股份有限公司 Centrifugal turntable mechanism for full-automatic immunity quantitative analyzer
TWI616526B (en) * 2017-05-15 2018-03-01 Cell separation and purification device

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418026A2 (en) * 1989-09-13 1991-03-20 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for pretreating cells for flow cytometry
JPH04242168A (en) * 1991-01-16 1992-08-28 Kurabo Ind Ltd Automatic plasmid separator
EP0559558A1 (en) * 1992-03-04 1993-09-08 Marteau d'Autry, Eric Automated sample filtration and identification
WO2000008472A2 (en) * 1998-08-04 2000-02-17 Dynex Technologies Inc. Automated immunoassay apparatus with flexible pick-up arm
WO2002062484A1 (en) * 2001-02-08 2002-08-15 Irm, Llc Automated centrifuge and method of using same
EP1407861A2 (en) * 2002-10-12 2004-04-14 Eppendorf Ag Gripping tool, dosing tool and tool holder for laboratory analyzer
US20070251341A1 (en) * 2006-04-28 2007-11-01 Johannes Balmer Carrier for positioning objects in relation to laboratory articles
DE102006027680A1 (en) * 2006-06-14 2007-12-20 Qiagen Gmbh Gripper unit for handling vessel used for receiving biological fluid has lid holder and recesses adapted to hold lid in defined position that is open position of lid in relation to vessel

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0418026A2 (en) * 1989-09-13 1991-03-20 Kabushiki Kaisha Tiyoda Seisakusho Apparatus for pretreating cells for flow cytometry
JPH04242168A (en) * 1991-01-16 1992-08-28 Kurabo Ind Ltd Automatic plasmid separator
EP0559558A1 (en) * 1992-03-04 1993-09-08 Marteau d'Autry, Eric Automated sample filtration and identification
WO2000008472A2 (en) * 1998-08-04 2000-02-17 Dynex Technologies Inc. Automated immunoassay apparatus with flexible pick-up arm
WO2002062484A1 (en) * 2001-02-08 2002-08-15 Irm, Llc Automated centrifuge and method of using same
EP1407861A2 (en) * 2002-10-12 2004-04-14 Eppendorf Ag Gripping tool, dosing tool and tool holder for laboratory analyzer
US20070251341A1 (en) * 2006-04-28 2007-11-01 Johannes Balmer Carrier for positioning objects in relation to laboratory articles
DE102006027680A1 (en) * 2006-06-14 2007-12-20 Qiagen Gmbh Gripper unit for handling vessel used for receiving biological fluid has lid holder and recesses adapted to hold lid in defined position that is open position of lid in relation to vessel

Cited By (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9274132B2 (en) 2010-07-23 2016-03-01 Beckman Coulter, Inc. Assay cartridge with reaction well
US9285382B2 (en) 2010-07-23 2016-03-15 Beckman Coulter, Inc. Reaction vessel
US8956570B2 (en) 2010-07-23 2015-02-17 Beckman Coulter, Inc. System and method including analytical units
US8962308B2 (en) 2010-07-23 2015-02-24 Beckman Coulter, Inc. System and method including thermal cycler modules
US9519000B2 (en) 2010-07-23 2016-12-13 Beckman Coulter, Inc. Reagent cartridge
US8996320B2 (en) 2010-07-23 2015-03-31 Beckman Coulter, Inc. System and method including analytical units
US8932541B2 (en) 2010-07-23 2015-01-13 Beckman Coulter, Inc. Pipettor including compliant coupling
US9140715B2 (en) 2010-07-23 2015-09-22 Beckman Coulter, Inc. System and method for controlling thermal cycler modules
US9046455B2 (en) 2010-07-23 2015-06-02 Beckman Coulter, Inc. System and method including multiple processing lanes executing processing protocols
US8840848B2 (en) 2010-07-23 2014-09-23 Beckman Coulter, Inc. System and method including analytical units
US9046506B2 (en) 2011-11-07 2015-06-02 Beckman Coulter, Inc. Specimen container detection
US9446418B2 (en) 2011-11-07 2016-09-20 Beckman Coulter, Inc. Robotic arm
US9482684B2 (en) 2011-11-07 2016-11-01 Beckman Coulter, Inc. Centrifuge system and workflow
US9506943B2 (en) 2011-11-07 2016-11-29 Beckman Coulter, Inc. Aliquotter system and workflow
US8973736B2 (en) 2011-11-07 2015-03-10 Beckman Coulter, Inc. Magnetic damping for specimen transport system

Also Published As

Publication number Publication date
SM200800035B (en) 2011-01-19
SM200800035A (en) 2010-01-19
WO2009150632A2 (en) 2009-12-17

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