WO2009137651A3 - Fungicidal substituted azoles - Google Patents

Fungicidal substituted azoles Download PDF

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Publication number
WO2009137651A3
WO2009137651A3 PCT/US2009/043096 US2009043096W WO2009137651A3 WO 2009137651 A3 WO2009137651 A3 WO 2009137651A3 US 2009043096 W US2009043096 W US 2009043096W WO 2009137651 A3 WO2009137651 A3 WO 2009137651A3
Authority
WO
WIPO (PCT)
Prior art keywords
substituted azoles
compounds
formula
disclosed
fungicidal substituted
Prior art date
Application number
PCT/US2009/043096
Other languages
French (fr)
Other versions
WO2009137651A2 (en
WO2009137651A8 (en
Inventor
Thomas Paul Selby
James Francis Bereznak
John Joseph Bisaha
Amy X. Ding
Vijayagopal Gopalsamuthiram
Mary Ann Hanagan
Jeffrey Keith Long
Andrew Edmund Taggi
Original Assignee
E. I. Du Pont De Nemours And Company
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E. I. Du Pont De Nemours And Company filed Critical E. I. Du Pont De Nemours And Company
Priority to EP09743637A priority Critical patent/EP2274284A2/en
Priority to US12/988,888 priority patent/US20110045101A1/en
Publication of WO2009137651A2 publication Critical patent/WO2009137651A2/en
Publication of WO2009137651A8 publication Critical patent/WO2009137651A8/en
Publication of WO2009137651A3 publication Critical patent/WO2009137651A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
    • A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
    • A01N43/647—Triazoles; Hydrogenated triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/68—Halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/88—Nitrogen atoms, e.g. allantoin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • C07D249/06—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles with aryl radicals directly attached to ring atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Abstract

Disclosed are compounds of Formula 1, including all geometric and stereoisomers, N-oxides, and salts thereof, wherein J is Q2 or R1; X is N, CR2 or CQ3; Y is N or CR3; Z is N or CR4; and Q1, Q2, Q3, R1 R2 and R3 are as defined in the disclosure. Also disclosed are compositions containing the compounds of Formula 1 and methods for controlling plant disease caused by a fungal pathogen comprising applying an effective amount of a compound or a composition of the invention.
PCT/US2009/043096 2008-05-08 2009-05-07 Fungicidal substituted azoles WO2009137651A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09743637A EP2274284A2 (en) 2008-05-08 2009-05-07 Fungicidal substituted azoles
US12/988,888 US20110045101A1 (en) 2009-05-06 2009-05-07 Fungicidal substituted azoles

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12699008P 2008-05-08 2008-05-08
US61/126,990 2008-05-08
PCT/US2009/042922 WO2009137538A2 (en) 2008-05-08 2009-05-06 Fungicidal substituted azoles
USPCT/US2009/042922 2009-05-06
USPCTUS01994/0922 2009-05-06

Publications (3)

Publication Number Publication Date
WO2009137651A2 WO2009137651A2 (en) 2009-11-12
WO2009137651A8 WO2009137651A8 (en) 2010-03-18
WO2009137651A3 true WO2009137651A3 (en) 2012-04-26

Family

ID=41119404

Family Applications (2)

Application Number Title Priority Date Filing Date
PCT/US2009/042922 WO2009137538A2 (en) 2008-05-08 2009-05-06 Fungicidal substituted azoles
PCT/US2009/043096 WO2009137651A2 (en) 2008-05-08 2009-05-07 Fungicidal substituted azoles

Family Applications Before (1)

Application Number Title Priority Date Filing Date
PCT/US2009/042922 WO2009137538A2 (en) 2008-05-08 2009-05-06 Fungicidal substituted azoles

Country Status (7)

Country Link
EP (1) EP2274284A2 (en)
AR (1) AR071769A1 (en)
CL (1) CL2009001094A1 (en)
PE (1) PE20091953A1 (en)
TW (1) TW200950698A (en)
UY (1) UY31811A (en)
WO (2) WO2009137538A2 (en)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR075713A1 (en) 2009-03-03 2011-04-20 Du Pont FUNGICIDE PIRAZOLS
US20120149661A1 (en) * 2009-08-26 2012-06-14 Novartis Ag Tetra-substituted heteroaryl compounds and their use as mdm2 and/or mdm4 modulators
TW201117722A (en) * 2009-11-04 2011-06-01 Du Pont Fungicidal mixtures
AR079545A1 (en) * 2009-12-21 2012-02-01 Bayer Cropscience Ag TIENILPIRI (MI) DINILAZOL
WO2012023143A1 (en) * 2010-08-19 2012-02-23 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
TW201245155A (en) * 2010-09-01 2012-11-16 Du Pont Fungicidal pyrazoles
TWI504350B (en) 2010-09-01 2015-10-21 Du Pont Fungicidal pyrazoles and their mixtures
BR112013007635A2 (en) * 2010-09-29 2016-07-26 Du Pont '' Selected compounds of formula 1, fungicidal composition and method for controlling plant diseases ''
TWI568721B (en) 2012-02-01 2017-02-01 杜邦股份有限公司 Fungicidal pyrazole mixtures
IN2015DN00202A (en) 2012-07-12 2015-06-12 Chiesi Farma Spa
WO2014130241A1 (en) 2013-02-20 2014-08-28 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
EP3036223A1 (en) 2013-08-20 2016-06-29 E. I. du Pont de Nemours and Company Fungicidal pyrazoles
WO2015171392A1 (en) 2014-05-06 2015-11-12 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
US10246420B2 (en) 2014-07-24 2019-04-02 Bayer Cropscience Aktiengesellschaft Pyrazole derivatives
CN107428694A (en) 2015-03-19 2017-12-01 杜邦公司 Antifungal pyrazoles
WO2018052838A1 (en) 2016-09-16 2018-03-22 E. I. Du Pont De Nemours And Company Fungicidal pyrazoles
TWI760428B (en) 2017-01-26 2022-04-11 日商三井化學Agro股份有限公司 Pyridone compound and germicide for agriculture and horticulture using the same as active ingredient
WO2018190350A1 (en) 2017-04-10 2018-10-18 三井化学アグロ株式会社 Pyridone compound, and agricultural and horticultural fungicide having this as active component
WO2018190351A1 (en) 2017-04-10 2018-10-18 三井化学アグロ株式会社 Pyridone compound, and agricultural and horticultural fungicide having this as active component
MY190386A (en) 2017-04-11 2022-04-20 Mitsui Chemicals Agro Inc Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients
PL3634417T3 (en) 2017-05-17 2023-09-25 Arcus Biosciences, Inc. Quinazoline-pyrazole derivatives for the treatment of cancer-related disorders
EP3636636B1 (en) 2017-06-08 2022-07-06 Mitsui Chemicals Agro, Inc. Pyridone compound and agricultural and horticultural fungicide
BR112020019804A2 (en) * 2018-03-30 2021-01-05 Sumitomo Chemical Company, Limited HETEROCYCLIC COMPOUND AND ARTHROPOD FEVER CONTROL COMPOSITION CONTAINING THE SAME
JP7328222B2 (en) 2018-07-24 2023-08-16 三井化学クロップ＆ライフソリューション株式会社 Pyridone compound and agricultural and horticultural fungicide containing it as an active ingredient
TWI828725B (en) 2018-07-25 2024-01-11 日商三井化學植保股份有限公司 Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients
WO2020113094A1 (en) 2018-11-30 2020-06-04 Nuvation Bio Inc. Pyrrole and pyrazole compounds and methods of use thereof
CN111819947B (en) * 2020-07-17 2022-03-04 新疆农业大学 Germination accelerating method beneficial to dormancy breaking of sorbus tianshanensis seeds
JP2023541152A (en) * 2020-09-14 2023-09-28 ジェンザイム・コーポレーション Compounds as modulators of bisphosphoglycerate mutase to treat sickle cell disease

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US5869509A (en) * 1996-07-31 1999-02-09 Bristol-Myers Squibb Company Diphenyl oxadiazolones as potassium channel modulators
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US5869509A (en) * 1996-07-31 1999-02-09 Bristol-Myers Squibb Company Diphenyl oxadiazolones as potassium channel modulators
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Also Published As

Publication number Publication date
WO2009137538A2 (en) 2009-11-12
PE20091953A1 (en) 2010-01-09
TW200950698A (en) 2009-12-16
AR071769A1 (en) 2010-07-14
EP2274284A2 (en) 2011-01-19
WO2009137538A3 (en) 2012-04-19
UY31811A (en) 2010-01-05
WO2009137651A2 (en) 2009-11-12
CL2009001094A1 (en) 2010-10-08
WO2009137651A8 (en) 2010-03-18

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