WO2009117032A3 - High throughput methods for analysis of contamination in environmental samples - Google Patents

High throughput methods for analysis of contamination in environmental samples Download PDF

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Publication number
WO2009117032A3
WO2009117032A3 PCT/US2008/087498 US2008087498W WO2009117032A3 WO 2009117032 A3 WO2009117032 A3 WO 2009117032A3 US 2008087498 W US2008087498 W US 2008087498W WO 2009117032 A3 WO2009117032 A3 WO 2009117032A3
Authority
WO
WIPO (PCT)
Prior art keywords
analysis
high throughput
methods
throughput methods
contamination
Prior art date
Application number
PCT/US2008/087498
Other languages
French (fr)
Other versions
WO2009117032A2 (en
Inventor
Anoop Agrawal
Juan Carlos L. Tonazzi
Lori L. Adams
John P. Cronin
Original Assignee
Ajjer Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajjer Llc filed Critical Ajjer Llc
Priority to CA2707035A priority Critical patent/CA2707035A1/en
Priority to GB1009308A priority patent/GB2468240A/en
Publication of WO2009117032A2 publication Critical patent/WO2009117032A2/en
Publication of WO2009117032A3 publication Critical patent/WO2009117032A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
    • B01L3/50255—Multi-well filtration
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/20—Metals
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
    • B01L2200/06—Fluid handling related problems
    • B01L2200/0689—Sealing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/04—Closures and closing means
    • B01L2300/046—Function or devices integrated in the closure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0829—Multi-well plates; Microtitration plates
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0289—Apparatus for withdrawing or distributing predetermined quantities of fluid
    • B01L3/0293—Apparatus for withdrawing or distributing predetermined quantities of fluid for liquids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/24—Earth materials

Abstract

Use of high throughput methods to analyze samples for toxic elements originating from industrial hygiene and environmental sampling are described. These methods utilize optical detection methods using plates with arrays and microwells. Methods to fabricate samples in such plates are described. The invention is particularly illustrated by demonstrating its applicability for analysis of beryllium by fluorescence. This invention also discloses the use of improved filtration method compatible with the high throughput methods of sample preparation and analysis.
PCT/US2008/087498 2007-12-19 2008-12-18 High throughput methods for analysis of contamination in environmental samples WO2009117032A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA2707035A CA2707035A1 (en) 2007-12-19 2008-12-18 High throughput methods for analysis of contamination in environmental samples
GB1009308A GB2468240A (en) 2007-12-19 2008-12-18 high throughput methods for analysis of contamination in environmental samples

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US822907P 2007-12-19 2007-12-19
US61/008,229 2007-12-19

Publications (2)

Publication Number Publication Date
WO2009117032A2 WO2009117032A2 (en) 2009-09-24
WO2009117032A3 true WO2009117032A3 (en) 2009-12-30

Family

ID=41091436

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/087498 WO2009117032A2 (en) 2007-12-19 2008-12-18 High throughput methods for analysis of contamination in environmental samples

Country Status (3)

Country Link
CA (1) CA2707035A1 (en)
GB (1) GB2468240A (en)
WO (1) WO2009117032A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2251453T3 (en) 2009-05-13 2014-07-07 Sio2 Medical Products Inc container Holder
US9458536B2 (en) 2009-07-02 2016-10-04 Sio2 Medical Products, Inc. PECVD coating methods for capped syringes, cartridges and other articles
US11624115B2 (en) 2010-05-12 2023-04-11 Sio2 Medical Products, Inc. Syringe with PECVD lubrication
US9878101B2 (en) 2010-11-12 2018-01-30 Sio2 Medical Products, Inc. Cyclic olefin polymer vessels and vessel coating methods
US9272095B2 (en) 2011-04-01 2016-03-01 Sio2 Medical Products, Inc. Vessels, contact surfaces, and coating and inspection apparatus and methods
CN102507554A (en) * 2011-10-26 2012-06-20 华南理工大学 Method for detecting beryllium content in water
EP2776603B1 (en) 2011-11-11 2019-03-06 SiO2 Medical Products, Inc. PASSIVATION, pH PROTECTIVE OR LUBRICITY COATING FOR PHARMACEUTICAL PACKAGE, COATING PROCESS AND APPARATUS
US11116695B2 (en) 2011-11-11 2021-09-14 Sio2 Medical Products, Inc. Blood sample collection tube
CA2887352A1 (en) 2012-05-09 2013-11-14 Sio2 Medical Products, Inc. Saccharide protective coating for pharmaceutical package
JP6509734B2 (en) 2012-11-01 2019-05-08 エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド Film inspection method
EP2920567B1 (en) 2012-11-16 2020-08-19 SiO2 Medical Products, Inc. Method and apparatus for detecting rapid barrier coating integrity characteristics
US9764093B2 (en) 2012-11-30 2017-09-19 Sio2 Medical Products, Inc. Controlling the uniformity of PECVD deposition
WO2014085346A1 (en) 2012-11-30 2014-06-05 Sio2 Medical Products, Inc. Hollow body with inside coating
WO2014134577A1 (en) 2013-03-01 2014-09-04 Sio2 Medical Products, Inc. Plasma or cvd pre-treatment for lubricated pharmaceutical package, coating process and apparatus
US9937099B2 (en) 2013-03-11 2018-04-10 Sio2 Medical Products, Inc. Trilayer coated pharmaceutical packaging with low oxygen transmission rate
KR102211788B1 (en) 2013-03-11 2021-02-04 에스아이오2 메디컬 프로덕츠, 인크. Coated Packaging
WO2014144926A1 (en) 2013-03-15 2014-09-18 Sio2 Medical Products, Inc. Coating method
WO2015148471A1 (en) 2014-03-28 2015-10-01 Sio2 Medical Products, Inc. Antistatic coatings for plastic vessels
CN116982977A (en) 2015-08-18 2023-11-03 Sio2医药产品公司 Medicaments and other packages with low oxygen transmission rate
KR101889910B1 (en) * 2016-12-15 2018-08-21 고려대학교 산학협력단 Method of Providing Information for Diagnosis of Mood Disorders Using Circadian Rhythms

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459040A (en) * 1993-11-22 1995-10-17 The Regents Of The University Of California Enzyme amplified, complex linked, competitive and non-competitive assays for the detection of metal ions
US20040138733A1 (en) * 2002-10-15 2004-07-15 Scimed Life Systems, Inc. Nano-actuated medical device
US20060068499A1 (en) * 1995-03-10 2006-03-30 Wohlstadter Jacob N Multi-array, multi-specific electrochemiluminescence testing
US20070048186A1 (en) * 1998-11-13 2007-03-01 Mesosystems Technology, Inc. Removing surface deposits of concentrated collected particles
US20070141715A1 (en) * 2004-03-30 2007-06-21 Los Alamos National Security, Llc Quantitative method of determining beryllium or a compound thereof in a sample

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5459040A (en) * 1993-11-22 1995-10-17 The Regents Of The University Of California Enzyme amplified, complex linked, competitive and non-competitive assays for the detection of metal ions
US20060068499A1 (en) * 1995-03-10 2006-03-30 Wohlstadter Jacob N Multi-array, multi-specific electrochemiluminescence testing
US20070048186A1 (en) * 1998-11-13 2007-03-01 Mesosystems Technology, Inc. Removing surface deposits of concentrated collected particles
US20040138733A1 (en) * 2002-10-15 2004-07-15 Scimed Life Systems, Inc. Nano-actuated medical device
US20070141715A1 (en) * 2004-03-30 2007-06-21 Los Alamos National Security, Llc Quantitative method of determining beryllium or a compound thereof in a sample

Also Published As

Publication number Publication date
GB201009308D0 (en) 2010-07-21
CA2707035A1 (en) 2009-09-24
GB2468240A (en) 2010-09-01
WO2009117032A2 (en) 2009-09-24

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