WO2009109099A1 - Scribble tool for a calibration sample used in an ion mobility spectrometer and its production and usage method - Google Patents
Scribble tool for a calibration sample used in an ion mobility spectrometer and its production and usage method Download PDFInfo
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- WO2009109099A1 WO2009109099A1 PCT/CN2009/000207 CN2009000207W WO2009109099A1 WO 2009109099 A1 WO2009109099 A1 WO 2009109099A1 CN 2009000207 W CN2009000207 W CN 2009000207W WO 2009109099 A1 WO2009109099 A1 WO 2009109099A1
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- calibration sample
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- ion mobility
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- shaped material
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0009—Calibration of the apparatus
Definitions
- the invention belongs to the field of chemical substance field detection, and in particular to a sample preparation tool for calibration samples for ion mobility spectrometer calibration and a method for manufacturing and using the same. Background technique
- Ion mobility spectrometry is a technology developed in the 1970s to separate and detect chemical substances under atmospheric pressure. It has extremely high sensitivity and response speed, and can detect and identify chemicals in a very short time. It can be used to detect chemical warfare agents, explosives, drugs, environmental pollutants, etc.
- the original ion mobility spectrometry technology was mainly used in the military field to detect chemical warfare agents. Because of its fast, sensitive, simple operation and convenient use, it has been widely used in anti-terrorism, virus detection, security inspection, environmental monitoring, etc. since the 1980s. field.
- Ion mobility meters are detected based on different migration times of various substances, and the migration time of substances is directly related to the operating environment of the instrument such as temperature and pressure.
- the migration time of the same substance at different temperatures or pressures is different. Therefore, the ion mobility spectrometer must calibrate the migration time according to the operating environment, especially the air pressure, to ensure the correct use of the instrument.
- the current ion mobility spectrometer can be calibrated according to environmental parameters, in order to ensure the accuracy of the ion mobility spectrometer detection and identification, in practical applications, calibration with standard materials is still required. Only when the migration time of other detectable substances is adjusted according to the measured migration time and changes of the standard substances can the ion migration lecturer detect and identify the accuracy.
- the inventors of the present application have developed a calibration sample preparation tool/pen containing a low concentration of a standard substance, and only need to use the tool/pen to sample during calibration.
- a simple drawing of the paper completes the sample preparation process of the standard test sample, making the calibration of the ion mobility spectrometer very simple.
- a method of manufacturing a scribing tool for providing a calibration sample for an ion mobility transmitter includes the steps of: providing a standard material having calibration characteristics; providing a corresponding shaped material; and dispersing the standard substance in A calibration sample is formed in the shaped material, wherein the predetermined calibration characteristic of the standard substance in the resulting calibration sample is substantially unchanged; and a scribing tool comprising the resulting calibration sample is fabricated.
- a scribing tool for providing a calibration sample for an ion mobility spectrometer includes a calibration sample consisting of a standard material having a calibration characteristic and a corresponding shaping material, wherein the standard material is There is basically no change in the distribution of the items.
- a chemical substance on-site detection method includes the steps of: providing an ion mobility spectrometer for detecting a chemical substance; providing a sampling paper; providing a writing tool according to the present invention; using the writing tool to sample A calibration sample is provided on the paper in a scribble manner; the ion mobility spectrometer is calibrated using the sample paper provided with the calibration sample; and the calibrated chemical ion spectroscopy instrument is used for on-site inspection of the chemical to be tested.
- the shaped material can be a solid or liquid shaped material.
- the weight content of the reference material in the calibration sample is preferably from 0.001% to 5%.
- the reference material may be trinitrotoluene, di-tert-butylmethylphenol, nicotinamide or other substance which can be detected by an ion mobility spectrometer.
- the scribing tool can be made into (active) crayons, chalk, pencils, refills, inks, and other suitable forms.
- the amount of reference material to be added should be appropriate.
- the content of the standard substance contained in the coated one should be higher than the detection limit of the instrument, and the instrument should not be poisoned.
- the detection sensitivity of different substances is different, and the amount of standard substances added should be determined by trial and error.
- the solid material used to make the sample preparation tool should be heated to about 20 CTC to remove the low-boiling interference, and then adjust the temperature of the solid material according to the melting point of the standard substance. It can be fully melted and dispersed in the matrix of solid materials without causing evaporation loss due to excessive temperature.
- calibration sample preparation tools are manufactured in the same manner as conventional writing instruments, except that a certain amount of standard material is added during the production process to form a solid or liquid low-concentration standard material writing material.
- the calibration sample preparation tool prepared by the method of the invention is convenient to store, carry and use, and is safe, reliable and environmentally friendly, which simplifies the calibration work of the ion mobility spectrometer, saves time and labor. detailed description
- 40 g stearic acid, 40 g paraffin wax, 5 g pigment and 15 g talc first heat the wax to about 200 °C to remove the interference, add 5-500 mg trinitrate when the temperature drops to about 100 Toluene, or di-tert-butylmethylphenol, or nicotinamide, melt and dissolve it, stir and mix, add talc powder and pigment, stir it, pour it into the copper mold, and then remove it after cooling.
- the pellets were pulverized by a pulverizer to a size of about 1 mm, and then sieved to remove particles having a diameter of not more than 0.05 mm and a diameter of not less than 2 mm to obtain yellow granules. Material.
- the yellow pellets prepared in advance were added thereto in an amount of 1.5 parts by weight.
- the mixture was put into a colored pen metal mold, solidified by water cooling, and then taken out from the metal mold to obtain a calibration preparation crayon of the present invention.
- the lead material is mixed in the following parts by weight,
- the mixture was fused in a lead core machine at a temperature of 10 CTC and the number of fusions was 5 times.
- the material for the pen holder is polyvinyl chloride (PVC) and a small amount of adjuvant, where epoxidized soybean oil and organotin can be used. Put the material of the pen bar into the pen bar machine and heat it to 135. The lead core machine extrudes the lead core into the pen bar machine to form the core, and cuts off the finished product of the pen bar machine by 20 cm length.
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Abstract
A scribble tool for a calibration sample used in an ion mobility spectrometer, a producing method and a usage method thereof are disclosed. A scribble tool with a low concentration standard substance can be obtained by adding a certain amounts of standard substance into the raw material for making the scribble tool and mixing the raw material with the standard substance evenly enough and then making the mixture into solid state after molding the mixture into a rod shaped mould or making the mixture into liquid state directly. Calibration sample can be prepared by drawing the tool/pen onto a sampling paper slightly when the ion mobility spectrometer needs to be calibrated.
Description
离子迁移谱仪用校准样品的涂写工具及其制造和使用方法 技术领域 Scribing tool for calibration sample of ion mobility spectrometer and method of manufacturing and using same
本发明属于化学物质现场检测领域， 具体地， 涉及一种离子 迁移谱仪校准用的校准样品的制样工具及其制造和使用方法。 背景技术 The invention belongs to the field of chemical substance field detection, and in particular to a sample preparation tool for calibration samples for ion mobility spectrometer calibration and a method for manufacturing and using the same. Background technique
离子迁移谱技术是上世纪 70年代发展起来的一种在大气压环 境下对化学物质进行分离和检测的技术， 具有极高的灵敏度和响 应速度， 能在极短的时间内检测和识别化学物质， 可用于检测识 别化学战剂， ***物品， 毒品， 环境污染物等。 最初离子迁移谱 技术主要应用于军事领域检测化学战剂， 由于该技术具有快速， 灵敏， 操作简单， 使用方便的特点， 80 年代开始， 已被广泛应用 于反恐， 查毒， 安检， 环境监测等领域。 Ion mobility spectrometry is a technology developed in the 1970s to separate and detect chemical substances under atmospheric pressure. It has extremely high sensitivity and response speed, and can detect and identify chemicals in a very short time. It can be used to detect chemical warfare agents, explosives, drugs, environmental pollutants, etc. The original ion mobility spectrometry technology was mainly used in the military field to detect chemical warfare agents. Because of its fast, sensitive, simple operation and convenient use, it has been widely used in anti-terrorism, virus detection, security inspection, environmental monitoring, etc. since the 1980s. field.
离子迁移錯仪是根据各种物质的不同迁移时间来检测识别的， 而物质的迁移时间与仪器的运行环境例如温度 , 气压等有直接的 关系。 同一物质在不同的温度或气压下， 其迁移时间是不同的， 因此， 离子迁移谱仪必须根据运行环境尤其是气压对迁移时间进 行校准， 才能保证仪器的正确使用。 尽管目前的离子迁移谱仪能 根据环境参数进行校准， 但为了确保离子迁移谱仪检测识别的准 确率， 在实际应用上， 还是要用标准物质进行校准。 只有根据标 准物质的实测迁移时间及变化情况对其它可检测物质的迁移时间 做出相应调整， 才能保证离子迁移讲仪检测识别的准确率。 Ion mobility meters are detected based on different migration times of various substances, and the migration time of substances is directly related to the operating environment of the instrument such as temperature and pressure. The migration time of the same substance at different temperatures or pressures is different. Therefore, the ion mobility spectrometer must calibrate the migration time according to the operating environment, especially the air pressure, to ensure the correct use of the instrument. Although the current ion mobility spectrometer can be calibrated according to environmental parameters, in order to ensure the accuracy of the ion mobility spectrometer detection and identification, in practical applications, calibration with standard materials is still required. Only when the migration time of other detectable substances is adjusted according to the measured migration time and changes of the standard substances can the ion migration lecturer detect and identify the accuracy.
目前， 在用固态物质作校准物质时， 如***物或毒品， 由于离 子迁移谱仪的灵敏度很高， 通常是用稀释点样的方法进行校准的， 即， 将标准物质配成低浓度的有机溶液， 滴加少量于采样纸上， 待溶剂挥发后把采样纸***仪器进样口进行检测校准。 使用该校 准方法存在如下所述的诸多问题： At present, when solid materials are used as calibration substances, such as explosives or drugs, because of the high sensitivity of the ion mobility spectrometer, it is usually calibrated by a dilution method, that is, the standard substance is formulated into a low concentration organic The solution is added dropwise to the sample paper. After the solvent evaporates, insert the sample paper into the instrument inlet for calibration. There are a number of problems with the use of this calibration method as follows:
( 1 ) 、 配制及现场使用标准物质溶液都需要一定的试验条件 和专业技能， 这提高了仪器的使用条件， 限制了离子迁移谱仪的 推广使用。 (1) Preparation and on-site use of standard substance solutions require certain test conditions and professional skills, which improves the conditions of use of the instrument and limits the use of ion mobility spectrometers.
( 2 ) 、 配制标准物质溶液需要用到有机溶剂， 而有机溶剂易
燃易爆易挥发， 贮存， 携带和使用都不安全。 (2), the preparation of the standard substance solution requires the use of organic solvents, and the organic solvent is easy Explosive, volatile, volatile, storage, carrying and use are not safe.
( 3 ) 、 有机溶剂有毒性易挥发， 会损害人员健康， 污染环境。 发明内容 (3) Organic solvents are toxic and volatile, which may damage the health of people and pollute the environment. Summary of the invention
为了克服溶液点样的不方便、 不安全、 不环保的缺点， 本申 请发明人研究出一种含低浓度标准物质的校准制样工具 /笔， 在校 准时只需用该工具 /笔在采样紙上轻轻一画， 就完成了标准测试样 本的制样过程， 从而使离子迁移谱仪的校准工作变得非常简单。 In order to overcome the inconvenience, unsafe, and environmentally friendly shortcomings of solution spotting, the inventors of the present application have developed a calibration sample preparation tool/pen containing a low concentration of a standard substance, and only need to use the tool/pen to sample during calibration. A simple drawing of the paper completes the sample preparation process of the standard test sample, making the calibration of the ion mobility spectrometer very simple.
根据本发明的一个方面，一种提供离子迁移傳仪用校准样品的 涂写工具的制造方法包括步骤： 提供具有校准特性的标准物质； 提供相应的赋形材料； 将所述标准物质均勾分散于所述赋形材料 中来形成校准样品， 其中所得校准样品中所述标准物质的所述预 定校准特性基本没有改变； 以及制造包含所得校准样品的涂写工 具。 According to one aspect of the invention, a method of manufacturing a scribing tool for providing a calibration sample for an ion mobility transmitter includes the steps of: providing a standard material having calibration characteristics; providing a corresponding shaped material; and dispersing the standard substance in A calibration sample is formed in the shaped material, wherein the predetermined calibration characteristic of the standard substance in the resulting calibration sample is substantially unchanged; and a scribing tool comprising the resulting calibration sample is fabricated.
根据本发明的另一个方面， 一种提供离子迁移谱仪用校准样 品的涂写工具包括校准样品， 所述校准样品由具有校准特性的标 准物质和相应的赋形材料组成， 其中所述标准物质均勾分散于所 品中基本没有改变。 According to another aspect of the invention, a scribing tool for providing a calibration sample for an ion mobility spectrometer includes a calibration sample consisting of a standard material having a calibration characteristic and a corresponding shaping material, wherein the standard material is There is basically no change in the distribution of the items.
根据本发明的又一个方面， 一种化学物质现场检测方法包括 步骤： 提供用于检测化学物质的离子迁移谱仪； 提供采样纸； 提 供根据本发明的涂写工具； 使用所述涂写工具来在采样纸上以涂 写方式提供校准样品； 利用被提供了校准样品的采样纸对所述离 子迁移谱仪进行校准； 以及利用校准后的所述离子迁移谱仪对待 检化学物质进行现场检测。 According to still another aspect of the present invention, a chemical substance on-site detection method includes the steps of: providing an ion mobility spectrometer for detecting a chemical substance; providing a sampling paper; providing a writing tool according to the present invention; using the writing tool to sample A calibration sample is provided on the paper in a scribble manner; the ion mobility spectrometer is calibrated using the sample paper provided with the calibration sample; and the calibrated chemical ion spectroscopy instrument is used for on-site inspection of the chemical to be tested.
赋形材料可以为固态或液态赋形材料。 The shaped material can be a solid or liquid shaped material.
校准样品中标准物质的重量含量优选为 0.001 %-5%。 The weight content of the reference material in the calibration sample is preferably from 0.001% to 5%.
标准物质可以为***、 二叔丁基甲基苯酚、 烟酰胺或其 它能被离子迁移谱仪检测识别的物质。 The reference material may be trinitrotoluene, di-tert-butylmethylphenol, nicotinamide or other substance which can be detected by an ion mobility spectrometer.
涂写工具可以制作为 （活动） 蜡笔、 粉笔、 铅笔、 笔芯、 墨 水以及其它合适的形式。 The scribing tool can be made into (active) crayons, chalk, pencils, refills, inks, and other suitable forms.
校准制样涂写工具 （笔） 的制作中需注意的是：
( 1 )、 标准物质的加入量要适当， 既要让所涂一笔中所含有 的标准物质含量高于仪器检测限， 又不可以使仪器中毒。 不同物 质的检测灵敏度不同， 其标准物质的加入量应通过试险确定。 Note the preparation of the calibration sample writing tool (pen): (1) The amount of reference material to be added should be appropriate. The content of the standard substance contained in the coated one should be higher than the detection limit of the instrument, and the instrument should not be poisoned. The detection sensitivity of different substances is different, and the amount of standard substances added should be determined by trial and error.
( 2 )、 石蜡 （蜡笔原料） 等用于制作制样工具的固体材料应 先加热至 20CTC左右， 以除去低沸点干扰物， 然后再根据标准物质 的熔点调整固体材料温度， 既要保证标准物质能充分熔化分散在 固体材料基质中， 又不会因温度过高造成蒸发损失。 (2), paraffin (crayon material), etc. The solid material used to make the sample preparation tool should be heated to about 20 CTC to remove the low-boiling interference, and then adjust the temperature of the solid material according to the melting point of the standard substance. It can be fully melted and dispersed in the matrix of solid materials without causing evaporation loss due to excessive temperature.
( 3 )、 制作器具必须清洗干净， 操作时应严防污染。 (3) The production equipment must be cleaned and the pollution should be strictly prevented during operation.
其他校准制样工具的制作与常规的书写工具的制作工艺相 同， 只是在制作的过程中加入一定量的标准物质， 以形成固态或 液态的低浓度标准物质涂写材料即可。 Other calibration sample preparation tools are manufactured in the same manner as conventional writing instruments, except that a certain amount of standard material is added during the production process to form a solid or liquid low-concentration standard material writing material.
通过本发明方法制备的校准制样工具贮存、 携带和使用都非 常筒单方便， 并且安全、 可靠、 环保， 简化了离子迁移谱仪的校 准工作， 省时省力。 具体实施方式 The calibration sample preparation tool prepared by the method of the invention is convenient to store, carry and use, and is safe, reliable and environmentally friendly, which simplifies the calibration work of the ion mobility spectrometer, saves time and labor. detailed description
下列实施例更详细地阐述了本发明， 但不应解释为是对其范 围的限制。 The following examples illustrate the invention in more detail, but are not to be construed as limiting its scope.
实施例 1 校准制样蜡笔 Example 1 Calibration Sample Crayon
40 g硬脂酸， 40 g固体石蜡， 5 g颜料和 15 g滑石粉， 先将蜡 加热熔化至 200 °C左右， 以除去干扰物， 在温度降至 100 左右时 加入 5-500 mg***， 或二叔丁基甲基苯酚， 或烟酰胺， 将 其熔化溶解并搅拌混勾， 加入滑石粉和颜料， 搅拌均勾， 趁热倒 入铜模， 冷却成型后将其取出。 40 g stearic acid, 40 g paraffin wax, 5 g pigment and 15 g talc, first heat the wax to about 200 °C to remove the interference, add 5-500 mg trinitrate when the temperature drops to about 100 Toluene, or di-tert-butylmethylphenol, or nicotinamide, melt and dissolve it, stir and mix, add talc powder and pigment, stir it, pour it into the copper mold, and then remove it after cooling.
实施例 2 校准制样蜡笔 Example 2 Calibration Sample Crayon
将滑石 16重量份、 膨润土 （ N i hon Yuk i Nendo公司制造） 1.2重量份、 C.I.颜料黄 1 2.4重量份和 C丄颜料白 6 1重量份以 及原料总重量 0.001 -50 %。的三硝基曱苯， 或二叔丁基甲基苯酚， 或烟酰胺投入到亨舍尔混合机中， 随后在搅拌下逐渐加入水， 从 而制成尺寸 0.5 ~ 3 mm的粒料。 16 parts by weight of talc, 1.2 parts by weight of bentonite (manufactured by N i hon Yuk i Nendo Co., Ltd.), 2.4 parts by weight of C.I. Pigment Yellow 1, and 61 parts by weight of C 丄 pigment white, and 0.001 to 50% by weight of the total raw material. The trinitroguanidine, or di-tert-butylmethylphenol, or nicotinamide was placed in a Henschel mixer, and then water was gradually added under stirring to prepare pellets having a size of 0.5 to 3 mm.
随后利用粉碎机粉碎该粒料至尺寸约 1 mm , 然后进行过筛以 除掉直径不大 0.05 mm和直径不小于 2 mm的颗粒， 获得黄色粒
料。 Subsequently, the pellets were pulverized by a pulverizer to a size of about 1 mm, and then sieved to remove particles having a diameter of not more than 0.05 mm and a diameter of not less than 2 mm to obtain yellow granules. Material.
将酮蜡 12.5重量份、 石蜡 3重量份和微晶蜡 1重量份通过在 100 ~ 120 °C加热而熔融， 向其中加入流态化石蜡 2 重量份和涂以 二氧化钛的云母颜料 3重量份， 然后混合物进行搅拌。 12.5 parts by weight of the ketone wax, 3 parts by weight of the paraffin wax and 1 part by weight of the microcrystalline wax were melted by heating at 100 to 120 ° C, and 2 parts by weight of the fluidized paraffin and 3 parts by weight of the titania-coated mica pigment were added thereto. The mixture is then stirred.
继而， 向其中加入预先制备的黄色粒料加入量为 1.5重量份。 该混合物投入到彩笔金属模具中， 经水冷却而凝固， 然后从金属 模具中取出从而获得本发明的校准制样蜡笔。 Then, the yellow pellets prepared in advance were added thereto in an amount of 1.5 parts by weight. The mixture was put into a colored pen metal mold, solidified by water cooling, and then taken out from the metal mold to obtain a calibration preparation crayon of the present invention.
实施例 3 校准制样粉笔 Example 3 Calibration Sample Chalk
将 5-500 mg三硝基曱苯， 或二叔丁基曱基苯酚， 或烟酰胺， 溶解于 130 g的热水中， 加入 100 g熟石膏， 搅拌均匀， 趁其糊状 时倒入粉笔模具中， 待其凝固成型后取出。 Dissolve 5-500 mg of trinitroguanidine, or di-tert-butyl nonylphenol, or nicotinamide in 130 g of hot water, add 100 g of plaster, mix well, and pour the chalk into the paste. In the mold, it is taken out after solidification molding.
实施例 4 校准制样墨水 Example 4 Calibration Sample Ink
• 将 5-500 mg***， 或二叔丁基甲基苯酚， 或烟酰胺， 溶解于 2 ml 乙醇， 然后加入 50 ml不含干扰物质的墨水， 混匀。 • Dissolve 5-500 mg of trinitrotoluene, or di-tert-butylmethylphenol, or nicotinamide in 2 ml of ethanol, then add 50 ml of ink containing no interfering substances and mix.
实施例 5 校准制样 4 笔 Example 5 Calibration Sample 4 Pen
将铅芯原料按下列重量份混合， The lead material is mixed in the following parts by weight,
石墨粉 166 g 硬脂酸钙 16.5 g Graphite powder 166 g calcium stearate 16.5 g
硬脂酸 6.6 g 氯化聚乙烯 3.3 g ***， 或二叔丁 基甲基苯酚， 或烟酰胺 5-500 mg Stearic acid 6.6 g Chlorinated polyethylene 3.3 g Trinitrotoluene, or di-tert-butylmethylphenol, or nicotinamide 5-500 mg
混合料放入铅芯机中熔合， 温度为 10CTC , 熔合次数为 5遍。 笔杆的原料为聚氯乙烯 （PVC 料） 和少量辅助剂， 在此可使 用环氧大豆油和有机锡。 将笔杆的原料放入笔杆机加温到 135 ， 铅芯机将铅芯挤出进入笔杆机穿芯成型， 将笔杆机出的成品按 20 cm长度切断即可。 The mixture was fused in a lead core machine at a temperature of 10 CTC and the number of fusions was 5 times. The material for the pen holder is polyvinyl chloride (PVC) and a small amount of adjuvant, where epoxidized soybean oil and organotin can be used. Put the material of the pen bar into the pen bar machine and heat it to 135. The lead core machine extrudes the lead core into the pen bar machine to form the core, and cuts off the finished product of the pen bar machine by 20 cm length.
虽然， 上文中已经用一般性说明及具体实施方案对本发明作 了详尽的描述， 但在本发明基础上， 可以对之作一些修改或改进， 这对本领域技术人员而言是显而易见的。 因此， 在不偏离本发明 精神的基础上所做的这些修改或改进， 均属于本发明要求保护的 范围。
Although the present invention has been described in detail with reference to the preferred embodiments of the present invention, it will be apparent to those skilled in the art. Therefore, such modifications or improvements made without departing from the spirit of the invention are intended to be within the scope of the invention.
Claims
1. 一种提供离子迁移谱仪用校准样品的涂写工具的制造方 法， 包括步骤： A method of manufacturing a scribing tool for providing a calibration sample for an ion mobility spectrometer, comprising the steps of:
提供具有校准特性的标准物质； Provide standard materials with calibration characteristics;
提供相应的赋形材料； Providing corresponding shaped materials;
将所迷标准物质均匀分散于所述赋形材料中来形成校准样品， 其中所得校准样品中所述标准物质的所述预定校准特性基本没有 改变； 以及 Dispersing the standard substance uniformly in the shaped material to form a calibration sample, wherein the predetermined calibration characteristic of the standard substance in the obtained calibration sample is substantially unchanged;
制造包含所得校准样品的涂写工具。 A scribing tool containing the resulting calibration sample is fabricated.
2. 权利要求 1 的方法， 其中所述赋形材料为固态赋形材料以 使所得校准样品为固态。 2. The method of claim 1 wherein the shaped material is a solid shaped material such that the resulting calibration sample is in a solid state.
3. 权利要求 1 的方法， 其中所述赋形材料为液态赋形材料以 使所得校准样品为液态。 3. The method of claim 1 wherein said shaped material is a liquid shaped material such that the resulting calibration sample is in a liquid state.
4. 权利要求 1 的方法， 其中所得校准样品中标准物质的重量 含量为 0.001 %-5%。 4. The method of claim 1 wherein the standard sample in the resulting calibration sample has a weight content of from 0.001% to 5%.
5. 一种提供离子迁移借仪用校准样品的涂写工具， 包括校准 样品， 所述校准样品由具有校准特性的标准物质和相应的赋形材 料组成， 其中所述标准物质均勾分散于所述赋形材料并且所述标 准物 的所述预定校准特性在所述校准样品中基本没有改变。 5. A scribing tool for providing a calibration sample for ion mobility, comprising a calibration sample, the calibration sample being composed of a standard material having a calibration characteristic and a corresponding shaping material, wherein the standard substance is uniformly dispersed in the The shaped material and the predetermined calibration characteristics of the standard are substantially unchanged in the calibration sample.
6. 权利要求 5 的涂写工具， 其中所述赋形材料为固态赋形材 料以使所述校准样品为固态。 6. The writing tool of claim 5, wherein the shaped material is a solid shaped material to render the calibration sample solid.
7. 权利要求 5 的涂写工具， 其中所述赋形材料为液态赋形材 料以使所述校准样品为液态。 7. The writing tool of claim 5, wherein the shaped material is a liquid shaped material to render the calibration sample liquid.
8. 权利要求 5 的涂写工具， 其中所述校准样品中标准物质的 重量含量为 0.001 %-5%。 8. The writing tool of claim 5, wherein the calibration sample has a weight content of the standard material of from 0.001% to 5%.
9. 权利要求 5 的涂写工具， 其中所迷标准物质为能被离子迁 移谱仪检测识别的***， 二叔丁基甲基苯酚或烟酰胺。 9. The writing tool of claim 5, wherein the standard substance is trinitrotoluene, di-tert-butylmethylphenol or nicotinamide which can be detected by an ion mobility spectrometer.
10. 权利要求 5的涂写工具， 其为蜡笔、 粉笔、 铅笔、 活动蜡 笔、 笔芯或墨水形式。 10. The writing tool of claim 5 in the form of a crayon, chalk, pencil, active crayon, refill or ink.
1 1 . 一种化学物质现场检测方法， 包括步骤： 1 1. A method for on-site detection of chemical substances, including steps:
提供用于检测化学物质的离子迁移谱仪；
提供采样纸； Providing an ion mobility spectrometer for detecting chemicals; Providing sampling paper;
提供如权利要求 5- 1 0之一所述的涂写工具； Providing a writing tool according to any one of claims 5 to 10;
使用所迷涂写工具来在采样纸上以涂写方式提供校准样品； 利用被提供了校准样品的釆样纸对所述离子迁移谱仪进行校 以及 Using the scribing tool to provide a calibration sample on the sample paper in a scribble manner; using the sample paper provided with the calibration sample to calibrate the ion mobility spectrometer
利用校准后的所述离子迁移谱仪对待检化学物质进行现场检
On-site inspection of chemical substances to be inspected using the calibrated ion mobility spectrometer
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN200810101386.X | 2008-03-05 | ||
| CN 200810101386 CN101526496B (en) | 2008-03-05 | 2008-03-05 | Method for preparing calibration sample of ion mobility spectrometer |
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| PCT/CN2009/000207 WO2009109099A1 (en) | 2008-03-05 | 2009-02-26 | Scribble tool for a calibration sample used in an ion mobility spectrometer and its production and usage method |
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| CN103076387B (en) * | 2013-01-11 | 2015-01-14 | 同济大学 | Identification method for writing time based on DART-TOF technique |
| CN107121486A (en) * | 2017-06-13 | 2017-09-01 | 雷创仪器（苏州）有限公司 | Ionic migration spectrometer standard sample pen |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627444B1 (en) * | 2000-08-07 | 2003-09-30 | Smiths Detection - Toronto Ltd. | Method and solid phase calibration sample for calibration of analytical instructions |
| US20070003435A1 (en) * | 2003-06-30 | 2007-01-04 | The Regents Of The University Of California | Inspection tester for explosives |
| WO2007070471A1 (en) * | 2005-12-12 | 2007-06-21 | Ge Security, Inc. | Calibration and verification tool and method for calibrating a detection apparatus |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1999041601A1 (en) * | 1998-02-11 | 1999-08-19 | Haley Lawrence V | Hand-held detection system using gc/ims |
| CN1916619A (en) * | 2005-08-19 | 2007-02-21 | 上海新漫传感技术研究发展有限公司 | Ion migration spectrometer based on sample through membrane |
| US20080101995A1 (en) * | 2005-12-16 | 2008-05-01 | Smiths Detection Inc. | Ion mobility spectrometer having improved sample receiving device |
| CN201130166Y (en) * | 2007-08-10 | 2008-10-08 | 上海新漫传感技术研究发展有限公司 | Multifunctional sampling apparatus for ion mobility spectrometer |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6627444B1 (en) * | 2000-08-07 | 2003-09-30 | Smiths Detection - Toronto Ltd. | Method and solid phase calibration sample for calibration of analytical instructions |
| US20070003435A1 (en) * | 2003-06-30 | 2007-01-04 | The Regents Of The University Of California | Inspection tester for explosives |
| WO2007070471A1 (en) * | 2005-12-12 | 2007-06-21 | Ge Security, Inc. | Calibration and verification tool and method for calibrating a detection apparatus |
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| CN101526496B (en) | 2013-06-19 |
| CN101526496A (en) | 2009-09-09 |
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