WO2009106980A3 - Indazole derivatives - Google Patents
Indazole derivatives Download PDFInfo
- Publication number
- WO2009106980A3 WO2009106980A3 PCT/IB2009/000409 IB2009000409W WO2009106980A3 WO 2009106980 A3 WO2009106980 A3 WO 2009106980A3 IB 2009000409 W IB2009000409 W IB 2009000409W WO 2009106980 A3 WO2009106980 A3 WO 2009106980A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- indazole derivatives
- mammal
- compounds
- human
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/54—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings condensed with carbocyclic rings or ring systems
- C07D231/56—Benzopyrazoles; Hydrogenated benzopyrazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/416—1,2-Diazoles condensed with carbocyclic ring systems, e.g. indazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Abstract
This invention relates to compounds, pharmaceutical compositions and methods for the treatment of a condition mediated by CB1 receptor activity in a mammalian subject including a human, which comprises administering to a mammal in need of such treatment a therapeutically effective amount of the compound of Formula (I): wherein R1, R2 and R3 are as defined in this specification.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3266708P | 2008-02-29 | 2008-02-29 | |
US61/032,667 | 2008-02-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009106980A2 WO2009106980A2 (en) | 2009-09-03 |
WO2009106980A3 true WO2009106980A3 (en) | 2009-10-29 |
Family
ID=40676297
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2009/000409 WO2009106980A2 (en) | 2008-02-29 | 2009-02-26 | Indazole derivatives |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2009106980A2 (en) |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7741350B1 (en) | 2009-01-28 | 2010-06-22 | Cara Therapeutics, Inc. | Bicyclic pyrazolo-heterocycles |
US8653127B2 (en) | 2009-01-28 | 2014-02-18 | Cara Therapeutics, Inc. | Bicyclic pyrazolo-heterocycles |
AU2014259534B2 (en) * | 2011-01-04 | 2016-05-19 | Novartis Ag | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (AMD) |
KR20140027090A (en) * | 2011-01-04 | 2014-03-06 | 노파르티스 아게 | Indole compounds or analogues thereof useful for the treatment of age-related macular degeneration (amd) |
WO2014002053A1 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
CN105121429B (en) | 2012-06-28 | 2017-12-12 | 诺华股份有限公司 | Complement pathway conditioning agent and its purposes |
EP2867227B1 (en) | 2012-06-28 | 2018-11-21 | Novartis AG | Complement pathway modulators and uses thereof |
WO2014002052A1 (en) | 2012-06-28 | 2014-01-03 | Novartis Ag | Pyrrolidine derivatives and their use as complement pathway modulators |
EP2867225B1 (en) | 2012-06-28 | 2017-08-09 | Novartis AG | Pyrrolidine derivatives and their use as complement pathway modulators |
CA2882724A1 (en) | 2012-07-12 | 2014-01-16 | Novartis Ag | Complement pathway modulators and uses thereof |
PH12015501492B1 (en) | 2013-01-08 | 2015-09-28 | Kalvista Pharmaceuticals Ltd | Benzylamine derivatives |
GB201300304D0 (en) | 2013-01-08 | 2013-02-20 | Kalvista Pharmaceuticals Ltd | Benzylamine derivatives |
TWI636047B (en) | 2013-08-14 | 2018-09-21 | 英商卡爾維斯塔製藥有限公司 | Heterocyclic derivatives |
EP2998743B1 (en) * | 2014-09-19 | 2018-02-21 | Randox Laboratories Ltd | Detection of indazole synthetic cannabinoids |
GB201421085D0 (en) | 2014-11-27 | 2015-01-14 | Kalvista Pharmaceuticals Ltd | New enzyme inhibitors |
GB201421083D0 (en) | 2014-11-27 | 2015-01-14 | Kalvista Pharmaceuticals Ltd | Enzyme inhibitors |
US9682940B2 (en) | 2015-08-25 | 2017-06-20 | Janssen Pharmaceutica Nv | Indazole derivatives useful as CB-1 inverse agonists |
CN108602775B (en) | 2016-01-14 | 2022-04-29 | 贝思以色列女会吏医学中心公司 | Mast cell modulators and uses thereof |
CN105709226A (en) * | 2016-01-20 | 2016-06-29 | 中国人民解放军第三军医大学第一附属医院 | Applications of CB2R (cannabinoid receptor 2) agonist in preparing medicines for treating hypertensive cerebral hemorrhage |
TW202222786A (en) | 2016-02-01 | 2022-06-16 | 美商百歐克斯製藥公司 | Benzopyrazole compounds and analogues thereof |
WO2017207983A1 (en) | 2016-05-31 | 2017-12-07 | Kalvista Pharmaceuticals Limited | Pyrazole derivatives as plasma kallikrein inhibitors |
GB201609603D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-[(6-cyano-2-fluoro-3-methoxyphenyl)Methyl]-3-(methoxymethyl)-1-({4-[(2-ox opyridin-1-YL)Methyl]phenyl}methyl)pyrazole-4-carboxamide |
GB201609607D0 (en) | 2016-06-01 | 2016-07-13 | Kalvista Pharmaceuticals Ltd | Polymorphs of N-(3-Fluoro-4-methoxypyridin-2-yl)methyl)-3-(methoxymethyl)-1-({4-((2-oxopy ridin-1-yl)methyl)phenyl}methyl)pyrazole-4-carboxamide and salts |
GB201719881D0 (en) | 2017-11-29 | 2018-01-10 | Kalvista Pharmaceuticals Ltd | Solid forms of plasma kallikrein inhibitor and salts thereof |
MD3716952T2 (en) | 2017-11-29 | 2022-06-30 | Kalvista Pharmaceuticals Ltd | Dosage forms comprising a plasma kallikrein inhibitor |
WO2020059660A1 (en) * | 2018-09-20 | 2020-03-26 | 日清食品ホールディングス株式会社 | Compound having enac activation potency |
JP7330828B2 (en) * | 2018-09-20 | 2023-08-22 | 日清食品ホールディングス株式会社 | Compound having ENaC activating ability |
WO2021028645A1 (en) | 2019-08-09 | 2021-02-18 | Kalvista Pharmaceuticals Limited | Plasma kallikrein inhibitors |
CN115348958A (en) * | 2020-01-30 | 2022-11-15 | 研究三角协会 | Indazole derivatives as partial agonists of cannabinoid receptors |
EP4305021A1 (en) * | 2021-03-10 | 2024-01-17 | Vincere Biosciences, Inc. | Usp30 inhibitors and uses thereof |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1301882A (en) * | 1969-04-01 | 1973-01-04 | ||
WO1996033713A1 (en) * | 1995-03-16 | 1996-10-31 | Eli Lilly And Company | Indazolecarboxamides |
WO2001058869A2 (en) * | 2000-02-11 | 2001-08-16 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases |
WO2004014864A1 (en) * | 2002-08-10 | 2004-02-19 | Astex Technology Limited | 1h-indazole-3-carboxamide compounds as cyclin dependent kinases (cdk) inhibitors |
WO2004031158A1 (en) * | 2002-10-02 | 2004-04-15 | Sanofi-Aventis | Indazolecarboxamide derivatives, preparation and use thereof as cdk1, cdk2 and cdk4 inhibitors |
WO2005037839A1 (en) * | 2003-10-14 | 2005-04-28 | Entomed | Norcantharidin derivative compounds, method for the production thereof, compositions containing said compounds and the use thereof |
WO2005092890A2 (en) * | 2004-03-25 | 2005-10-06 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
WO2005099703A1 (en) * | 2004-03-16 | 2005-10-27 | Sanofi-Aventis | Use of indazolecarboxamide derivatives for the preparation of a medicament that is intended for the treatment and prevention of paludism |
EP2020232A1 (en) * | 2007-08-03 | 2009-02-04 | Zeltia, S.A. | N-(1-thiazolyl)-amide derivatives for the treatment of obesity, diabetes and cardiovascular diseases |
-
2009
- 2009-02-26 WO PCT/IB2009/000409 patent/WO2009106980A2/en active Application Filing
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1301882A (en) * | 1969-04-01 | 1973-01-04 | ||
WO1996033713A1 (en) * | 1995-03-16 | 1996-10-31 | Eli Lilly And Company | Indazolecarboxamides |
WO2001058869A2 (en) * | 2000-02-11 | 2001-08-16 | Bristol-Myers Squibb Company | Cannabinoid receptor modulators, their processes of preparation, and use of cannabinoid receptor modulators in treating respiratory and non-respiratory diseases |
WO2004014864A1 (en) * | 2002-08-10 | 2004-02-19 | Astex Technology Limited | 1h-indazole-3-carboxamide compounds as cyclin dependent kinases (cdk) inhibitors |
WO2004031158A1 (en) * | 2002-10-02 | 2004-04-15 | Sanofi-Aventis | Indazolecarboxamide derivatives, preparation and use thereof as cdk1, cdk2 and cdk4 inhibitors |
WO2005037839A1 (en) * | 2003-10-14 | 2005-04-28 | Entomed | Norcantharidin derivative compounds, method for the production thereof, compositions containing said compounds and the use thereof |
WO2005099703A1 (en) * | 2004-03-16 | 2005-10-27 | Sanofi-Aventis | Use of indazolecarboxamide derivatives for the preparation of a medicament that is intended for the treatment and prevention of paludism |
WO2005092890A2 (en) * | 2004-03-25 | 2005-10-06 | Memory Pharmaceuticals Corporation | Indazoles, benzothiazoles, benzoisothiazoles, benzisoxazoles, and preparation and uses thereof |
EP2020232A1 (en) * | 2007-08-03 | 2009-02-04 | Zeltia, S.A. | N-(1-thiazolyl)-amide derivatives for the treatment of obesity, diabetes and cardiovascular diseases |
Also Published As
Publication number | Publication date |
---|---|
WO2009106980A2 (en) | 2009-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009106980A3 (en) | Indazole derivatives | |
MX2010009462A (en) | Indazole derivatives. | |
WO2011027249A3 (en) | Benzimidazole derivatives | |
WO2009111700A3 (en) | Oxadiazoanthracene compounds for the treatment of diabetes | |
WO2009155121A3 (en) | Inhibitors of pi3 kinase | |
WO2007135527A3 (en) | Benzimidazolyl compounds | |
WO2008152099A3 (en) | Aryl/hetarylamides as modulators of the ep2 receptor | |
WO2009069032A3 (en) | Novel glucocorticoid receptor agonists | |
GEP20135744B (en) | Quinuclidine carbonate derivatives and medicinal compositions containing the same | |
WO2010017545A3 (en) | Triazole compounds that modulate hsp90 activity | |
WO2011127333A3 (en) | Compounds for treating disease, for administering, and for pharmaceutical compositions | |
WO2008007211A8 (en) | Substituted n-bicyclicalkyl bicyclic carboxyamide compounds | |
WO2008013987A3 (en) | N-alkyl substituted piperazinylmethylquinazolinones and azepanylmethylquinazolinones | |
WO2009025785A3 (en) | Cb2 receptor ligands for the treatment of pain | |
MY161607A (en) | Ester pro-drugs of [3-(1-(1h-imidazol-4-yl)ethyl)-2-methylphenyl] methanol for treating skin diseases and conditions | |
WO2009036996A3 (en) | Small molecule bradykinin b1 receptor antagonists | |
WO2008059370A8 (en) | Substituted bicyclocarboxyamide compounds | |
MX2014005075A (en) | Meglumine salt formulations of 1-(5,6-dichloro-1h-benzo[d]imidazo l-2-yl)-1h-pyrazole-4-carboxylic acid. | |
WO2008050199A3 (en) | Substituted phenylmethyl bicyclocarboxyamide compounds | |
GEP20135806B (en) | Lactams as beta secretase inhibitors | |
MY183111A (en) | 3-(heteroaryl-amino)-1,2,3,4-tetrahydro-9h-carbazole derivatives and their use as prostaglandin d2 receptor modulators | |
WO2008098978A3 (en) | Benzofuran compounds useful in the treatment of conditions mediated by the action of pge2 at the ep1 receptor | |
WO2008116663A3 (en) | Heterocyclyl-substituted-tetrahydro-naphthalen-amine derivatives, their preparation and use as medicaments | |
WO2006031782A3 (en) | Salvinorin derivatives as opioid receptor ligands | |
NZ609596A (en) | Cyclohexane derivative compound |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 09716041 Country of ref document: EP Kind code of ref document: A2 |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 09716041 Country of ref document: EP Kind code of ref document: A2 |