WO2009071725A3 - Use of valproate for the treatment of fear and phobia in subjects with alzheimer's disease - Google Patents

Use of valproate for the treatment of fear and phobia in subjects with alzheimer's disease Download PDF

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Publication number
WO2009071725A3
WO2009071725A3 PCT/ES2008/000765 ES2008000765W WO2009071725A3 WO 2009071725 A3 WO2009071725 A3 WO 2009071725A3 ES 2008000765 W ES2008000765 W ES 2008000765W WO 2009071725 A3 WO2009071725 A3 WO 2009071725A3
Authority
WO
WIPO (PCT)
Prior art keywords
valproate
phobia
alzheimer
fear
disease
Prior art date
Application number
PCT/ES2008/000765
Other languages
Spanish (es)
French (fr)
Other versions
WO2009071725A2 (en
Inventor
Antolin Carlos Alberto Saura
Louzao Catalina Casas
Llort Lydia Gimenez
Agusti Judit Espana
Original Assignee
Univ Barcelona Autonoma
Antolin Carlos Alberto Saura
Louzao Catalina Casas
Llort Lydia Gimenez
Agusti Judit Espana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Barcelona Autonoma, Antolin Carlos Alberto Saura, Louzao Catalina Casas, Llort Lydia Gimenez, Agusti Judit Espana filed Critical Univ Barcelona Autonoma
Publication of WO2009071725A2 publication Critical patent/WO2009071725A2/en
Publication of WO2009071725A3 publication Critical patent/WO2009071725A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The invention relates to the use of valproate for the production of a drug for the treatment of fear and phobia in a subject with Alzheimer's disease. The invention also relates to a method for the treatment of fear and phobia in a subject with Alzheimer's disease, whereby the subject is administered an effective quantity of valproate.
PCT/ES2008/000765 2007-12-07 2008-12-05 Use of valproate for the treatment of fear and phobia in subjects with alzheimer's disease WO2009071725A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200703252 2007-12-07
ES200703252A ES2325824B1 (en) 2007-12-07 2007-12-07 USE OF VALPROATO FOR THE TREATMENT OF FEAR AND FOBIA IN SUBJECTS WITH ALZHEIMER'S DISEASE.

Publications (2)

Publication Number Publication Date
WO2009071725A2 WO2009071725A2 (en) 2009-06-11
WO2009071725A3 true WO2009071725A3 (en) 2009-07-23

Family

ID=40718260

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2008/000765 WO2009071725A2 (en) 2007-12-07 2008-12-05 Use of valproate for the treatment of fear and phobia in subjects with alzheimer's disease

Country Status (2)

Country Link
ES (1) ES2325824B1 (en)
WO (1) WO2009071725A2 (en)

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DAVIS, L.L. ET AL.: "Comprehensive review of the psychiatric uses of valproate", JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY, vol. 20, no. SUP. 1, 2000, pages 1S - 17S *
KINRYS, G. ET AL.: "Valproic acid for the treatment of social anxiety disorder", INTERNATIONAL CLINICAL PSYCHOPHARMACOLOGY, vol. 18, 2003, pages 169 - 172 *
PRIMEAU, F. ET AL.: "Valproic acid and panic disorder", CAN. J. PSYCHIATRY, vol. 35, 1990, pages 248 - 250 *
TOWNSEND, M.H. ET AL.: "Comorbid anxiety disorders and divalproex sodium use among partial hospital patients with psychotic disorders", COMPREHENSIVE PSYCHIATRY, vol. 46, 2005, pages 368 - 370 *

Also Published As

Publication number Publication date
WO2009071725A2 (en) 2009-06-11
ES2325824A1 (en) 2009-09-18
ES2325824B1 (en) 2010-07-08

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