WO2009069727A1 - 生体高分子およびポリペプチドの化学修飾方法 - Google Patents
生体高分子およびポリペプチドの化学修飾方法 Download PDFInfo
- Publication number
- WO2009069727A1 WO2009069727A1 PCT/JP2008/071611 JP2008071611W WO2009069727A1 WO 2009069727 A1 WO2009069727 A1 WO 2009069727A1 JP 2008071611 W JP2008071611 W JP 2008071611W WO 2009069727 A1 WO2009069727 A1 WO 2009069727A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- biopolymer
- chemically modifying
- compound
- chemically modified
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
- C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
- C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/64—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent
- A61K47/6435—Drug-peptide, drug-protein or drug-polyamino acid conjugates, i.e. the modifying agent being a peptide, protein or polyamino acid which is covalently bonded or complexed to a therapeutically active agent the peptide or protein in the drug conjugate being a connective tissue peptide, e.g. collagen, fibronectin or gelatin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08H—DERIVATIVES OF NATURAL MACROMOLECULAR COMPOUNDS
- C08H1/00—Macromolecular products derived from proteins
- C08H1/06—Macromolecular products derived from proteins derived from horn, hoofs, hair, skin or leather
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Public Health (AREA)
- Materials Engineering (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Polymers & Plastics (AREA)
- Peptides Or Proteins (AREA)
- Materials For Medical Uses (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/745,214 US8507659B2 (en) | 2007-11-28 | 2008-11-28 | Method for chemically modifying biopolymer and polypeptide |
EP08854075.2A EP2221334B1 (en) | 2007-11-28 | 2008-11-28 | Method for chemically modifying biopolymer and polypeptide |
JP2009543860A JP5497449B2 (ja) | 2007-11-28 | 2008-11-28 | 生体高分子およびポリペプチドの化学修飾方法 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2007307161 | 2007-11-28 | ||
JP2007-307161 | 2007-11-28 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2009069727A1 true WO2009069727A1 (ja) | 2009-06-04 |
Family
ID=40678616
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/JP2008/071611 WO2009069727A1 (ja) | 2007-11-28 | 2008-11-28 | 生体高分子およびポリペプチドの化学修飾方法 |
Country Status (4)
Country | Link |
---|---|
US (1) | US8507659B2 (ja) |
EP (1) | EP2221334B1 (ja) |
JP (1) | JP5497449B2 (ja) |
WO (1) | WO2009069727A1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012046717A1 (ja) * | 2010-10-05 | 2012-04-12 | 独立行政法人物質・材料研究機構 | 2成分系組織接着剤及びその製造方法 |
WO2012046759A1 (ja) * | 2010-10-05 | 2012-04-12 | 独立行政法人物質・材料研究機構 | 組織接着膜及びその製造方法 |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
TWI776821B (zh) | 2016-11-01 | 2022-09-11 | 美商愛羅海德製藥公司 | α-V β-6整合素配位子 |
BR112020006901A2 (pt) | 2017-11-01 | 2020-10-13 | Arrowhead Pharmaceuticals, Inc. | ligantes de integrina e usos dos mesmos |
Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04189833A (ja) * | 1990-11-16 | 1992-07-08 | Takeda Chem Ind Ltd | ケラチン有機溶媒液およびその製造法 |
JPH05214092A (ja) * | 1991-10-21 | 1993-08-24 | Ortho Pharmaceut Corp | Pegイミデート類およびそれらの蛋白質誘導体 |
EP1014176A2 (en) | 1998-12-23 | 2000-06-28 | Fuji Photo Film B.V. | Silver halide emulsions containing recombinant gelatin-like proteins |
JP2001224677A (ja) | 1999-12-09 | 2001-08-21 | Buaayu:Kk | 光硬化性組織接着剤 |
JP2002531182A (ja) | 1998-12-03 | 2002-09-24 | ネアーリッヒ、ミヒャエル | 多孔質複合マトリックス並びにその製造方法及び使用法 |
US6645712B1 (en) | 1999-06-24 | 2003-11-11 | Fuji Photo Film B.V. | Oil-in-water emulsion stabilized with recombinant collagen-like material |
EP1398324A1 (en) | 2002-09-11 | 2004-03-17 | Fuji Photo Film B.V. | Use of recombinant gelatin-like proteins as plasma expanders and compositions suitable for plasma substitution |
EP0926543B1 (en) | 1997-12-24 | 2004-05-12 | Fuji Photo Film B.V. | Silver halide emulsions with recombinant collagen suitable for photographic application and also the preparation thereof |
WO2004085473A2 (en) | 2003-03-28 | 2004-10-07 | Fuji Photo Film B.V. | Rgd-enriched gelatine-like proteins with enhanced cell binding |
JP2004532802A (ja) | 2000-10-18 | 2004-10-28 | ヴァージニア コモンウェルス ユニバーシティ インテレクチュアル プロパティー ファンデーション | 薬剤送達および細胞被包における電気処理 |
JP2004321484A (ja) | 2003-04-24 | 2004-11-18 | Sangaku Renkei Kiko Kyushu:Kk | 医療用高分子ナノ・マイクロファイバー |
JP2006063283A (ja) * | 2004-08-30 | 2006-03-09 | Q P Corp | 高分子組成物およびその製造方法、ならびに成形体 |
WO2008072379A1 (ja) * | 2006-12-13 | 2008-06-19 | Fujifilm Corporation | 修飾された生体高分子の製造方法及び生体高分子の架橋方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3097051A (en) * | 1958-11-18 | 1963-07-09 | Ricardo H Wade | Cellulose ester anhydrides in fiber form |
US4076870A (en) * | 1975-10-01 | 1978-02-28 | Daido-Maruta Finishing Co. Ltd. | Process for treating fibrous products containing cellulosic fibers |
US4745178A (en) * | 1987-04-22 | 1988-05-17 | Eli Lilly And Company | Process for selective peptide bond cleavage using sulfoxides and CF3 CO |
US5298243A (en) * | 1988-10-20 | 1994-03-29 | Denki Kagaku Kogyo Kabushiki Kaisha | Colony stimulating factor-gelatin conjugate |
US5521097A (en) * | 1991-08-28 | 1996-05-28 | Seiko Instruments Inc. | Method of determining amino acid sequence of protein or peptide from carboxy-terminal |
AU9558901A (en) | 2000-10-05 | 2002-04-15 | Ares Trading Sa | Regioselective liquid phase pegylation |
DE102004024635A1 (de) * | 2004-05-12 | 2005-12-08 | Deutsche Gelatine-Fabriken Stoess Ag | Verfahren zur Herstellung von Formkörpern auf Basis von vernetzter Gelatine |
US20080269119A1 (en) | 2004-08-13 | 2008-10-30 | May Griffith | Ophthalmic Device and Related Methods and Compositions |
US8168592B2 (en) * | 2005-10-21 | 2012-05-01 | Amgen Inc. | CGRP peptide antagonists and conjugates |
US20070100091A1 (en) * | 2005-10-31 | 2007-05-03 | Anantharaman Dhanabalan | Crosslinked poly(arylene ether) composition, method, and article |
-
2008
- 2008-11-28 WO PCT/JP2008/071611 patent/WO2009069727A1/ja active Application Filing
- 2008-11-28 EP EP08854075.2A patent/EP2221334B1/en active Active
- 2008-11-28 US US12/745,214 patent/US8507659B2/en active Active
- 2008-11-28 JP JP2009543860A patent/JP5497449B2/ja active Active
Patent Citations (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH04189833A (ja) * | 1990-11-16 | 1992-07-08 | Takeda Chem Ind Ltd | ケラチン有機溶媒液およびその製造法 |
JPH05214092A (ja) * | 1991-10-21 | 1993-08-24 | Ortho Pharmaceut Corp | Pegイミデート類およびそれらの蛋白質誘導体 |
EP0926543B1 (en) | 1997-12-24 | 2004-05-12 | Fuji Photo Film B.V. | Silver halide emulsions with recombinant collagen suitable for photographic application and also the preparation thereof |
JP2002531182A (ja) | 1998-12-03 | 2002-09-24 | ネアーリッヒ、ミヒャエル | 多孔質複合マトリックス並びにその製造方法及び使用法 |
EP1014176A2 (en) | 1998-12-23 | 2000-06-28 | Fuji Photo Film B.V. | Silver halide emulsions containing recombinant gelatin-like proteins |
US6645712B1 (en) | 1999-06-24 | 2003-11-11 | Fuji Photo Film B.V. | Oil-in-water emulsion stabilized with recombinant collagen-like material |
JP2001224677A (ja) | 1999-12-09 | 2001-08-21 | Buaayu:Kk | 光硬化性組織接着剤 |
JP2004532802A (ja) | 2000-10-18 | 2004-10-28 | ヴァージニア コモンウェルス ユニバーシティ インテレクチュアル プロパティー ファンデーション | 薬剤送達および細胞被包における電気処理 |
EP1398324A1 (en) | 2002-09-11 | 2004-03-17 | Fuji Photo Film B.V. | Use of recombinant gelatin-like proteins as plasma expanders and compositions suitable for plasma substitution |
WO2004085473A2 (en) | 2003-03-28 | 2004-10-07 | Fuji Photo Film B.V. | Rgd-enriched gelatine-like proteins with enhanced cell binding |
JP2004321484A (ja) | 2003-04-24 | 2004-11-18 | Sangaku Renkei Kiko Kyushu:Kk | 医療用高分子ナノ・マイクロファイバー |
JP2006063283A (ja) * | 2004-08-30 | 2006-03-09 | Q P Corp | 高分子組成物およびその製造方法、ならびに成形体 |
WO2008072379A1 (ja) * | 2006-12-13 | 2008-06-19 | Fujifilm Corporation | 修飾された生体高分子の製造方法及び生体高分子の架橋方法 |
Non-Patent Citations (1)
Title |
---|
See also references of EP2221334A4 |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2012046717A1 (ja) * | 2010-10-05 | 2012-04-12 | 独立行政法人物質・材料研究機構 | 2成分系組織接着剤及びその製造方法 |
WO2012046759A1 (ja) * | 2010-10-05 | 2012-04-12 | 独立行政法人物質・材料研究機構 | 組織接着膜及びその製造方法 |
JP5594633B2 (ja) * | 2010-10-05 | 2014-09-24 | 独立行政法人物質・材料研究機構 | 2成分系組織接着剤及びその製造方法 |
JP5747264B2 (ja) * | 2010-10-05 | 2015-07-08 | 国立研究開発法人物質・材料研究機構 | 組織接着膜及びその製造方法 |
US9499728B2 (en) | 2010-10-05 | 2016-11-22 | National Institute For Materials Science | Two-component tissue adhesive and method for producing same |
Also Published As
Publication number | Publication date |
---|---|
EP2221334A1 (en) | 2010-08-25 |
EP2221334B1 (en) | 2016-12-28 |
JP5497449B2 (ja) | 2014-05-21 |
EP2221334A4 (en) | 2011-08-24 |
US20100323421A1 (en) | 2010-12-23 |
US8507659B2 (en) | 2013-08-13 |
JPWO2009069727A1 (ja) | 2011-04-14 |
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