WO2009039743A8 - 一种抑制酪氨酸酶基因表达的siRNA及组合物和应用 - Google Patents
一种抑制酪氨酸酶基因表达的siRNA及组合物和应用 Download PDFInfo
- Publication number
- WO2009039743A8 WO2009039743A8 PCT/CN2008/072142 CN2008072142W WO2009039743A8 WO 2009039743 A8 WO2009039743 A8 WO 2009039743A8 CN 2008072142 W CN2008072142 W CN 2008072142W WO 2009039743 A8 WO2009039743 A8 WO 2009039743A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- tyro
- sirnas
- tyrosinase gene
- compositions
- useful
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
- A61K8/606—Nucleosides; Nucleotides; Nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/18—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with another compound as one donor, and incorporation of one atom of oxygen (1.14.18)
- C12Y114/18001—Tyrosinase (1.14.18.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering N.A.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Molecular Biology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Biotechnology (AREA)
- Dermatology (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Virology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN2008801029315A CN101820921B (zh) | 2007-09-20 | 2008-08-26 | 一种抑制酪氨酸酶基因表达的siRNA及组合物和应用 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN200710153058.X | 2007-09-20 | ||
CN200710153058 | 2007-09-20 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2009039743A1 WO2009039743A1 (en) | 2009-04-02 |
WO2009039743A8 true WO2009039743A8 (zh) | 2010-04-01 |
Family
ID=40510753
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CN2008/072142 WO2009039743A1 (en) | 2007-09-20 | 2008-08-26 | Sirnas useful for inhibiting expression of tyrosinase gene, the compositions comprising the sirnas and their uses |
Country Status (2)
Country | Link |
---|---|
CN (1) | CN101820921B (zh) |
WO (1) | WO2009039743A1 (zh) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102793639A (zh) * | 2011-12-16 | 2012-11-28 | 百奥迈科生物技术有限公司 | 一种植物提取物介导的药物透皮导入***及其透皮方法 |
WO2017017523A1 (en) * | 2015-07-27 | 2017-02-02 | Olix Pharmaceuticals, Inc. | Rna complexes that inhibit melanin production |
KR20180025701A (ko) * | 2016-09-01 | 2018-03-09 | (주)아모레퍼시픽 | 특정 siRNA을 포함하는 멜라닌 증진용 조성물 |
CN110643596A (zh) * | 2018-06-26 | 2020-01-03 | 煌鼎科技有限公司 | 一种美白酵母dna原料的制法 |
CN110066800B (zh) * | 2019-04-30 | 2019-12-24 | 厦门甘宝利生物医药有限公司 | 一种化合物及其组合物的应用 |
CN113667669B (zh) * | 2021-08-06 | 2023-12-22 | 暨南大学 | 抑制酪氨酸酶表达的反义寡核苷酸及其应用 |
CN117070583B (zh) * | 2023-10-16 | 2024-05-14 | 吉林凯莱英制药有限公司 | 抑制PCSK9基因表达的siRNA的制备方法 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1506041A (zh) * | 2002-12-12 | 2004-06-23 | 殷冬生 | 基因皮肤美白化妆品的配方和制造方法 |
US7504385B2 (en) * | 2003-12-17 | 2009-03-17 | Avon Products, Inc. | si-RNA-mediated gene silencing technology to inhibit tyrosinase and reduce pigmentation |
FR2890859B1 (fr) * | 2005-09-21 | 2012-12-21 | Oreal | Oligonucleotide d'arn double brin inhibant l'expression de la tyrosinase |
CN101601635A (zh) * | 2008-06-13 | 2009-12-16 | 殷勤伟 | 小rna/dna美白产品的配方和制造方法 |
-
2008
- 2008-08-26 WO PCT/CN2008/072142 patent/WO2009039743A1/zh active Application Filing
- 2008-08-26 CN CN2008801029315A patent/CN101820921B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN101820921B (zh) | 2012-07-25 |
WO2009039743A1 (en) | 2009-04-02 |
CN101820921A (zh) | 2010-09-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2009039743A8 (zh) | 一种抑制酪氨酸酶基因表达的siRNA及组合物和应用 | |
WO2007064857A3 (en) | Amphoteric liposome formulation | |
WO2008152131A3 (en) | Rnai inhibition of alpha-enac expression | |
WO2011008730A3 (en) | Chemical modification of small hairpin rnas for inhibition of gene expression | |
WO2009043353A3 (en) | Micromirs | |
EP4086347A3 (en) | Selective antisense compounds and uses thereof | |
WO2012018881A3 (en) | Methods and compositions for the regulation of rna | |
WO2008085221A3 (en) | Therapeutic use of cd31 expressing cells | |
EP2313491A4 (en) | METHODS, COMPOSITIONS AND SYSTEMS FOR BIOSYNTHETIC BIOPRODUCTION OF 1,4-BUTANEDIOL | |
WO2005118824A3 (en) | Methods and compositions for the inhibition of gene expression | |
WO2008131419A3 (en) | Glycoconjugates of rna interference agents | |
WO2007027894A3 (en) | Antisense compounds having enhanced anti-microrna activity | |
SG165394A1 (en) | Modulation of immunostimulatory properties of short interfering ribonucleic acid (sirna) by nucleotide modification | |
WO2007090073A3 (en) | Oligomeric compounds and compositions for the use in modulation of micrornas | |
WO2009129465A3 (en) | Compositions and methods for inhibiting expression of xbp-1 gene | |
WO2009006297A3 (en) | Methods for altering the genome of a monocot plant cell | |
WO2010033225A3 (en) | Compositions and methods for the specific inhibition of gene expression by dsrna | |
WO2008130437A3 (en) | Modified cyanobacteria | |
WO2012024573A3 (en) | Compositions comrpising perivascular stem cells and nell-1 protein | |
WO2010135836A8 (en) | Novel beta-glucosidase enzymes | |
WO2009108217A3 (en) | Compositions comprising k-ras sirna and methods of use | |
WO2011116152A3 (en) | Delivery of agents using interfering nanoparticles | |
WO2007144779A3 (en) | Compositions comprising porphyra and methods of making and using thereof | |
WO2012054664A3 (en) | Ink compositions | |
WO2010013815A1 (ja) | 標的遺伝子の発現を抑制する組成物 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
WWE | Wipo information: entry into national phase |
Ref document number: 200880102931.5 Country of ref document: CN |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application |
Ref document number: 08784132 Country of ref document: EP Kind code of ref document: A1 |
|
NENP | Non-entry into the national phase in: |
Ref country code: DE |
|
122 | Ep: pct application non-entry in european phase |
Ref document number: 08784132 Country of ref document: EP Kind code of ref document: A1 |