WO2009008756A3 - DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF - Google Patents

DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF Download PDF

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Publication number
WO2009008756A3
WO2009008756A3 PCT/PT2008/000026 PT2008000026W WO2009008756A3 WO 2009008756 A3 WO2009008756 A3 WO 2009008756A3 PT 2008000026 W PT2008000026 W PT 2008000026W WO 2009008756 A3 WO2009008756 A3 WO 2009008756A3
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WO
WIPO (PCT)
Prior art keywords
acid
plasmid
dna sequence
specific
sequence encoding
Prior art date
Application number
PCT/PT2008/000026
Other languages
French (fr)
Other versions
WO2009008756A4 (en
WO2009008756A2 (en
Inventor
Da Fonseca Cesar Simoes
Hahn-Haegerdal Rita Baerbel
Vieira Martins Isabel Maria Spencer
Original Assignee
Univ Nova De Lisboa
Da Fonseca Cesar Simoes
Hahn-Haegerdal Rita Baerbel
Spencer Vieira Martins Isabel
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Nova De Lisboa, Da Fonseca Cesar Simoes, Hahn-Haegerdal Rita Baerbel, Spencer Vieira Martins Isabel filed Critical Univ Nova De Lisboa
Priority to EP08766990A priority Critical patent/EP2167533A2/en
Publication of WO2009008756A2 publication Critical patent/WO2009008756A2/en
Publication of WO2009008756A3 publication Critical patent/WO2009008756A3/en
Publication of WO2009008756A4 publication Critical patent/WO2009008756A4/en

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • C07K14/39Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts
    • C07K14/395Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi from yeasts from Saccharomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02EREDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
    • Y02E50/00Technologies for the production of fuel of non-fossil origin
    • Y02E50/10Biofuels, e.g. bio-diesel

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention refers to host cells genetically modified microorganisms by introducing a nucleic acid sequence encoding a specific L-arabinose transporter from yeast. The host cells are preferably those of an eukaryotic microorganism such as yeasts or filamentous fungi. The invention is useful for the complete use of sugar obtained from plant biomass and other ligno-cellulose materials of biotechnological importance in the production of biofuels, bulk and platform chemicals including ethanol, butanol, lactate, 1,4-diacids (succinate, fumaric, malic), glycerol, sorbitol, mannitol, xylitol/arabinitol, L-ascorbic acid, xylitol, hydrogen gas, 2,5-furan dicarboxylic acid, 3-hydroxy propionic acid, aspartic acid, glutaric acid, glutamic acid, itaconic acid, levulinic acid, and 3-hydroxybutyrolactone, fatty acids, fatty-derived molecules, isoprenoids, isoprenoid-derived molecules, alkanes, isopentanol, isoamylacetate, using genetically-modified microorganisms to consume and ferment L-arabinose in hexose and pentose mixtures resulting from renewable raw materials.
PCT/PT2008/000026 2007-07-06 2008-07-04 DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF WO2009008756A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP08766990A EP2167533A2 (en) 2007-07-06 2008-07-04 DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PT103780A PT103780A (en) 2007-07-06 2007-07-06 SEQUENCE OF DNA CODING A SPECIFIC TRANSPORTER FOR L-ARABINOSE, CDNA MOLECULE, PLASMIDE, UNDERSTANDING THE AFFECTED DNA SEQUENCE, HOST CELL TRANSFORMED WITH THAT PLUMBING AND APPLICATION.
PT103780 2007-07-06

Publications (3)

Publication Number Publication Date
WO2009008756A2 WO2009008756A2 (en) 2009-01-15
WO2009008756A3 true WO2009008756A3 (en) 2009-03-05
WO2009008756A4 WO2009008756A4 (en) 2009-04-23

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/PT2008/000026 WO2009008756A2 (en) 2007-07-06 2008-07-04 DNA SEQUENCE ENCODING A SPECIFIC L-ARABINOSE TRANSPORTER, A cDNA MOLECULE, A PLASMID COMPRISING THE SAID DNA SEQUENCE, HOST CELL TRANSFORMED WITH SUCH PLASMID AND APPLICATION THEREOF

Country Status (3)

Country Link
EP (1) EP2167533A2 (en)
PT (1) PT103780A (en)
WO (1) WO2009008756A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8237035B1 (en) 2008-04-15 2012-08-07 Pioneer Hi Bred International Inc Maize variety PHVNV
WO2011059314A1 (en) * 2009-11-12 2011-05-19 Stichting Voor De Technische Wetenschappen Pentose transporters and uses thereof
DE102011081649A1 (en) 2011-08-26 2013-02-28 Evonik Röhm Gmbh Longer chain methacrylates from renewable raw materials
WO2013049711A1 (en) 2011-09-29 2013-04-04 Bio Architecture Lab, Inc. Methods for preparing 2,5-furandicarboxylic acid
US9598689B2 (en) 2011-11-10 2017-03-21 Lallemand Hungary Liquidity Management Llc Genetically modified strain of S. cerevisiae engineered to ferment xylose and arabinose

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095627A1 (en) * 2002-05-08 2003-11-20 Forskarpatent I Syd Ab A modified yeast consuming l-arabinose
WO2006096130A1 (en) * 2005-03-11 2006-09-14 Forskarpatent I Syd Ab Arabinose- and xylose-fermenting saccharomyces cerevisiae strains
WO2007143247A2 (en) * 2006-06-02 2007-12-13 Midwest Research Institute Cloning and characterization of l-arabinose transporters from non-conventional yeast
WO2008080505A1 (en) * 2006-12-20 2008-07-10 Johann Wolfgang Goethe-Universität Frankfurt am Main Novel specific arabinose transporter from the yeast pichia stipitis, and uses thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003095627A1 (en) * 2002-05-08 2003-11-20 Forskarpatent I Syd Ab A modified yeast consuming l-arabinose
WO2006096130A1 (en) * 2005-03-11 2006-09-14 Forskarpatent I Syd Ab Arabinose- and xylose-fermenting saccharomyces cerevisiae strains
WO2007143247A2 (en) * 2006-06-02 2007-12-13 Midwest Research Institute Cloning and characterization of l-arabinose transporters from non-conventional yeast
WO2008080505A1 (en) * 2006-12-20 2008-07-10 Johann Wolfgang Goethe-Universität Frankfurt am Main Novel specific arabinose transporter from the yeast pichia stipitis, and uses thereof

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
ANTONIUS J A VAN MARIS ET AL: "Alcoholic fermentation of carbon sources in biomass hydrolysates by Saccharomyces cerevisiae: current status", ANTONIE VAN LEEUWENHOEK, KLUWER ACADEMIC PUBLISHERS, DO, vol. 90, no. 4, 11 October 2006 (2006-10-11), pages 391 - 418, XP019446684, ISSN: 1572-9699 *
ANU SALOHEIMO ET AL: "Xylose transport studies with xylose-utilizing Saccharomyces cerevisiae strains expressing heterologous and homologous permeases", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 74, no. 5, 19 December 2006 (2006-12-19), pages 1041 - 1052, XP019489542, ISSN: 1432-0614 *
BÄRBEL HAHN-HÄGERDAL ET AL: "Towards industrial pentose-fermenting yeast strains", APPLIED MICROBIOLOGY AND BIOTECHNOLOGY, SPRINGER, BERLIN, DE, vol. 74, no. 5, 9 February 2007 (2007-02-09), pages 937 - 953, XP019489564, ISSN: 1432-0614 *
BECKER JESSICA ET AL: "A modified Saccharomyces cerevisiae strain that consumes L-arabinose and produces ethanol", 20030701; 20030700, vol. 69, no. 7, 1 July 2003 (2003-07-01), pages 4144 - 4150, XP009080581 *
FONSECA C ET AL: "L-Arabinose transport and catabolism in yeast", FEBS JOURNAL, BLACKWELL PUBLISHING, LONDON, GB, vol. 274, July 2007 (2007-07-01), pages 3589 - 3600, XP007903587, ISSN: 1742-464X *
HAHN-HÄGERDAL BÄRBEL ET AL: "Metabolic engineering for pentose utilization in Saccharomyces cerevisiae.", ADVANCES IN BIOCHEMICAL ENGINEERING/BIOTECHNOLOGY 2007, vol. 108, 2007, pages 147 - 177, XP002506192, ISSN: 0724-6145 *
WISSELINK H WOUTER ET AL: "Engineering of Saccharomyces cerevisiae for efficient anaerobic alcoholic fermentation of L-arabinose", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 73, no. 15, 2007, pages 4881 - 4891, XP009090726, ISSN: 0099-2240 *

Also Published As

Publication number Publication date
PT103780A (en) 2009-01-06
EP2167533A2 (en) 2010-03-31
WO2009008756A4 (en) 2009-04-23
WO2009008756A2 (en) 2009-01-15

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