WO2008155080A2 - Styrene/acrylate copolymers in cosmetic sun protection agents - Google Patents

Styrene/acrylate copolymers in cosmetic sun protection agents Download PDF

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Publication number
WO2008155080A2
WO2008155080A2 PCT/EP2008/004821 EP2008004821W WO2008155080A2 WO 2008155080 A2 WO2008155080 A2 WO 2008155080A2 EP 2008004821 W EP2008004821 W EP 2008004821W WO 2008155080 A2 WO2008155080 A2 WO 2008155080A2
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WO
WIPO (PCT)
Prior art keywords
preparation
ethylhexyl
styrene
cosmetic
triazine
Prior art date
Application number
PCT/EP2008/004821
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German (de)
French (fr)
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WO2008155080A3 (en
Inventor
Tanja Westphal
Sophie Viala
Heike Lerg
Craig Zoltowski
Original Assignee
Beiersdorf Ag
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Publication of WO2008155080A2 publication Critical patent/WO2008155080A2/en
Publication of WO2008155080A3 publication Critical patent/WO2008155080A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers

Definitions

  • the present invention relates to styrene / acrylate copolymers in cosmetic preparations.
  • UVA and UVB filters are summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the German Cosmetics Regulation.
  • a special form of cosmetic sunscreen products are the so-called waterproof sunscreen.
  • a waterproof sunscreen protects the user not only after bathing, but also protects him during the bathing from sunburn.
  • W / O formulations are generally advantageous.
  • W / O emulsions often have unsatisfactory cosmetic properties: when applied to the skin leave a greasy, shiny and sometimes sticky impression and - especially on hairy skin - difficult to distribute.
  • Viscose O / W emulsions and thin-bodied sprays have less of a greasy effect on the skin, are rather mattifying and quickly penetrate the skin. They are generally perceived by consumers as lighter and more cosmetically elegant than W / O emulsions. However, since water is the outer phase, O / W emulsions are usually only partially waterproof.
  • copolymers of polyvinylpyrrolidone for example the PVP hexadecene copolymer and the PVP eicosene copolymer, which are available under the trade names Antaron V216 and Antaron V220 from the GAF Chemicals Cooperation, as well as the Tricontayl PVP and the like.
  • the water resistance and weld strength of the prior art formulations is limited.
  • sunscreen on the skin after bathing again.
  • this has the disadvantage that, in order to obtain an effective UV protection, he has an increased consumption of sunscreen.
  • the binding ability of the UV filter in or on the skin is of great importance for the water resistance of the formulation. It is understandable that oil-soluble UV filters are better bound to the (lipophilic) surface of the skin or are more difficult to wash off this than water-soluble UV filters.
  • a further object of the invention was therefore to arrive at preparations (in particular O / W formulations) in a simple and inexpensive manner, which are distinguished by good water resistance.
  • preparations should be found which have a high content of water-soluble UV filters and nevertheless show a very good water resistance.
  • cosmetic preparation comprising a) styrene / acrylate copolymers and b) one or more UV light protection filters.
  • the invention also relates to the use of styrene / acrylate copolymers to increase the water resistance of cosmetic sunscreens.
  • the invention also provides the use of styrene / acrylate copolymers to increase the perspiration resistance of cosmetic sunscreens.
  • the preparations according to the invention can be prepared simply and inexpensively.
  • the styrene / acrylate copolymers according to the invention have a glass transition temperature of less than or equal to 20 0 C.
  • Glass transition temperature is measured according to the invention as follows: The meter “DSC 822e” was used Mettler, the sample was filled in a perforated 40 .mu.l aluminum crucible has been detected in the temperature range from -140 0 C to +150 0 C 1 heating rate 10 °. C / min, was measured over two temperature cycles, for evaluation, the second heating curve was used.
  • the copolymer according to the invention is advantageously built up from the following monomers:
  • (b) acrylic acid and / or methacrylic acid and / or compounds having the structure H 2 C CR 1 Y, where R 1 is hydrogen or methyl and Y is both -COOR 2 and COO X + .
  • R 2 stands for straight-chain or branched alkyl groups, straight-chain or branched alkylene groups, each of which may also be substituted.
  • X + denotes lithium, sodium, potassium, magnesium, calcium, aluminum, ammonium, mono- / di- / tri and tetraalkylammonium ions.
  • Copolymers of acrylate monomers, methacrylate monomers, acrylic acid, methacrylic acid and styrene are preferred according to the invention.
  • the styrene / acrylate copolymers according to the invention are obtainable, for example, under the trade names Joncryl 1532 and Joncryl ECO 2124 from BASF Resins.
  • copolymers of styrene, 2-ethylhexyl acrylate, butyl acrylate, methyl methacrylate and acrylic acid eg Joncryl ECO 21214
  • copolymers Sytrol, 2-ethylhexyl acrylate, isobutyl acrylate, methyl methacrylate, butyl acrylate, acrylic acid, methacrylic acid eg Joncryl 1532.
  • the preparation according to the invention contains styrene / acrylate copolymer in a concentration of 0.1 to 30% by weight, based on the total weight of the preparation.
  • the preparation according to the invention contains styrene / acrylate copolymer in a concentration of 0.5 to 15% by weight, based on the total weight of the preparation.
  • the preparation according to the invention contains UV light protection filters in a total amount of from 0.2 to 40% by weight, based on the total weight of the preparation.
  • the preparation according to the invention contains UV light protection filters in a total amount of from 0.5 to 30% by weight, based on the total weight of the preparation.
  • Dioctylbutylamidotriazone (INCI: diethylhexyl-butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -6- (2-ethylhexyl) -imino-1,3,5-triazine with the CAS no.
  • the pigments can advantageously be surface-treated ("coated"), in which case for example a hydrophilic, amphiphilic or hydrophobic character is to be formed or is to be retained.
  • This surface treatment can consist in that the pigments are prepared by processes known per se be provided with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer.
  • the various surface coatings may also contain water for the purposes of the present invention.
  • Inorganic surface coatings for the purposes of the present invention may consist of aluminum oxide (Al 2 O 3 ), aluminum hydroxide Al (OH) 3 or aluminum oxide hydrate (also: Alumina, CAS No .: 1333-84-2), sodium hexametaphosphate (NaPO 3 J 6 , sodium metaphosphate (NaPO 3 ) n , silicon dioxide (SiO 2 ) (also: silica, CAS No .: 7631-86-9), barium sulfate (BaSO 4 ) or iron oxide (Fe 2 O 3 ) Inorganic surface coatings may occur alone, in combination and / or in combination with organic coating materials.
  • Organic surface coatings for the purposes of the present invention may consist of vegetable or animal aluminum stearate, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 Dimethylsiloxane units and silica gel) or alginic acid. These organic surface coatings may be present alone, in combination and / or in combination with inorganic coating materials.
  • the preparation contains, as further ingredients, one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, Phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carbitin, carnosine, polydocanol, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, ß-alanine, tocopheryl acetate, urea; hyaluronic acid; dihydroxyacetone; 8-hexadecene-1,16-dicarboxylic acid and / or licochalcone A contains.
  • one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, Phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carbitin, carnosine, polydocanol, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine
  • ingredients are preferably used according to the invention in a single concentration of 0.001 to 5% by weight, based on the total weight of the preparation.
  • Preparations which are advantageous according to the invention can also be obtained by the preparation according to the invention containing one or more compounds selected from the group consisting of parabens, phenoxyethanol, ethylhexylglycerol, 2-methylpropane-1,3-diol, butylene glycol, propylene glycol.
  • ingredients are preferably used according to the invention in a single concentration of 0.001 to 5% by weight, based on the total weight of the preparation.
  • the preparation according to the invention has a viscosity of 100 to 20,000 mPaS.
  • a viscosity from 300 to 10,000 mPas, measured in each case with the measuring device: Haake Viscotester VT-02 at 25 0 C.
  • the preparations according to the invention may also advantageously contain repellents for protection against mosquitoes, ticks and spiders and the like.
  • repellents for protection against mosquitoes, ticks and spiders and the like.
  • Advantageous z. N, N-diethyl-3-methylbenzamide (trade name: Meta-delphene, "DEET"), dimethyl phthalate (trade name: Palatinol M, DMP), 1-piperidinecarboxylic acid 2- (2-hydroxyethyl) -1-methylpropyl ester, and especially 3- (Nn-butyl-N-acetyl-amino) -propionic acid ethyl ester (available commercially from Merck under the tradename Insekt Repellent® 3535.)
  • the repellents can be used either singly or in combination.
  • Moisturizers are substances or mixtures of substances which give cosmetic preparations the property of reducing the moisture release of the horny layer (also called transepidermal water loss (TEWL) after application or spreading on the skin surface) and / or hydrating the horny layer positively influence.
  • TEWL transepidermal water loss
  • humectants for the purposes of the present invention are, for example, glycerol, lactic acid and / or lactates, in particular sodium lactate, butylene glycol, propylene glycol, biosaccharide gum-1, glycine soya, ethylhexyloxyglycerol, pyrrolidonecarboxylic acid and urea.
  • polymers Moisturizer from the group of water-soluble and / or water-swellable and / or water-gelable polysaccharides to use.
  • hyaluronic acid chitosan and / or a fucose-rich polysaccharide
  • chitosan and / or a fucose-rich polysaccharide
  • Fucogel®1000 of the company SOLABIA SA is available.
  • Moisturizers can also be used advantageously as anti-wrinkle active ingredients for protection against skin changes, as described, for example, in US Pat. B. occur during skin aging, can be used.
  • the inventive preparation one or more humectants in a total concentration of 0.1 to 20% by weight and preferably in a total concentration of 0.5 to 10% by weight, each based on the total weight of Preparation containing.
  • the cosmetic preparations according to the invention may also advantageously, although not necessarily, contain fillers which are e.g. B. the sensory and cosmetic
  • Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as, for example, tapioca starch, distarch phosphate, aluminum or sodium starch, octenylsuccinate and the like), pigments which have neither mainly UV filter nor coloring action (such as, for example, US Pat. B. boron nitride etc.) and / or Aerosils ® (CAS no. 7631-86-9) and / or talc.
  • starch and starch derivatives such as, for example, tapioca starch, distarch phosphate, aluminum or sodium starch, octenylsuccinate and the like
  • pigments which have neither mainly UV filter nor coloring action such as, for example, US Pat. B. boron nitride etc.
  • Aerosils ® CAS no. 7631-86-9
  • the aqueous phase of the preparations according to the invention may advantageously comprise customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol, diols or polyols of low C number and their ethers, preferably propylene glycol, 2-methylpropane-1, 3-diol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, polymers, foam stabilizers, electrolytes, self-tanning agents.
  • customary cosmetic auxiliaries for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol, diols or polyols of low C number and their ethers, preferably propylene glycol, 2-methylpropane-1, 3-dio
  • the preparation of the invention in addition to the copolymer according to the invention also contain other polymers, for example polysaccharides or their derivatives, for.
  • polysaccharides or their derivatives for example, hyaluronic acid, xanthan gum, hydroxypropylmethylcellulose, polyacrylates (here, for example, Carbopols types 980, 981, 1382, 2984, 5984, each individually or in combination).
  • Further polymers are those with the INCI name Acrylates / C 10-30 alkyl acrylate crosspolymer (eg Pemulen TR 1, Pemulen TR 2, Carbopol 1382 from the company NOVEON), Aristoflex AVC (INCI: ammonium acryloyldimethyltaurate / VP copolymer ), as well as Acrylic Acid / VP Crosspolymer (Ultrathix P-100, ISP).
  • the oil phase of the preparation according to the invention is advantageously selected from the group of polar oils, for example from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of from 8 to 24, in particular 12 to 18 carbon atoms.
  • the fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, such as.
  • Cocoglyceride olive oil, sunflower oil, jojoba oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, thistle oil, evening primrose oil, macadamia nut oil and the like.
  • Also advantageous according to the invention are z.
  • natural waxes of animal and vegetable origin such as beeswax and other insect waxes and berry wax, shea butter and / or lanolin (wool wax).
  • further advantageous polar oil components can furthermore be selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or or unbranched alcohols having a chain length of 3 to 30 carbon atoms and from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms.
  • ester oils can then advantageously be selected from the group consisting of phenethyl benzoate, 2-phenylethyl benzoate, isopropyl lauroyl sarcosinate, phenyl trimethicone, cyclomethicone, dibutyl adipate, octyl palmitate, octyl cocoate, octyl isostearate, octyldodeceyl myristate, octyldodecanol, cetearyl isononanoate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n Butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-
  • the oil phase can be advantageously selected from the group of dialkyl ethers and dialkyl carbonates, advantageous z.
  • the oil component from the group consisting of isoeicosane, neopentyl tylglykoldiheptanoat, dicaprylate / dicaprate propylene glycol, caprylic / capric / diglyceryl succinate, butylene glycol dicaprylate / dicaprate, C 12 -i 3 alkyl lactate, di-C 12-i 3 -Alkyltartrat , Triisostearin, dipentamer / thrityl hexacaprylate / hexacaprate, propylene glycol monoisostearate, tricaprylin, dimethyisiso- sorbid, myristyl myristate, isodecyl neopentanoate. It is particularly advantageous if the oil phase of the formulations according to the invention has a content of C 12-15 -alkyl benzoate or consists entirely of this.
  • Advantageous oil components are also z.
  • B. Butyloctylsalicylat for example, that available under the trade name Hallbrite BHB at the company. CP Hall
  • tridecyl salicylate which is available under the trade name Cosmacol ESI from Fa. Sasol
  • C12-C15 alkyl salicylate under the trade name Dermol NS in the Fa Alzo available
  • hexadecyl benzoate and butyl octyl benzoate and mixtures thereof Hallstar AB
  • Hallbrite TQ or Corapan TQ from Symrise Butyloctylsalicylat
  • tridecyl salicylate which is available under the trade name Cosmacol ESI from Fa. Sasol
  • C12-C15 alkyl salicylate under the trade name Dermol NS in the Fa Alzo available
  • Hallstar AB hexadecyl benzoate and butyl octyl be
  • the oil phase can also advantageously contain non-polar oils, for example those which are selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, Vaseline (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes, C13- 16 isoparaffin, isohexadecane, dimethicone and cyclomethicone.
  • non-polar oils for example those which are selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, Vaseline (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes, C13- 16 isoparaffin, isohexadecane, dimethicone and cyclomethicone.
  • non-polar oils for example those which are selected from the group of branched and unbranched hydrocarbons and waxes,
  • the siloxane elastomer (s) are in the form of spherical powders or in the form of gels.
  • siloxane elastomers are those with the INCI name dimethicone / vinyl dimethicone crosspolymer, for example that available from DOW CORNING under the trade names DOW CORNING 9506 Powder available.
  • siloxane elastomer is used in combination with oils of hydrocarbons of animal and / or vegetable origin, synthetic oils, synthetic esters, synthetic ethers or mixtures thereof.
  • compositions are also obtained when antioxidants are used as additives or active ingredients.
  • the preparations advantageously contain one or more antioxidants.
  • antioxidants all suitable or common for cosmetic applications antioxidants can be used.
  • water-soluble antioxidants can be used, such as vitamins, eg. As ascorbic acid and its derivatives.
  • antioxidants are vitamin E and its derivatives as well as vitamin A and its derivatives.
  • the amount of the antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 0.1 to 10 wt .-%, based on the total weight the preparation.
  • vitamin E and / or its derivatives are the antioxidant (s), it is advantageous to choose their respective concentrations from the range from 0.001 to 10% by weight, based on the total weight of the formulation.
  • vitamin A or vitamin A derivatives, or carotenes or derivatives thereof are the antioxidant (s), it is advantageous if their respective concentrations are in the range from 0.001 to 10% by weight, based on the total weight of the formulation choose. It is particularly advantageous if the cosmetic preparations according to the present invention contain cosmetic active ingredients, preferred active substances being antioxidants which can protect the skin against oxidative stress.
  • Inventive formulations which z. B. known anti-wrinkle active ingredients such as flavone glycosides (especially ⁇ -glycosyl rutin), coenzyme Q10, vitamin E and / or derivatives and the like, are particularly advantageous for protection against aesthetically unattractive skin lesions, as described for.
  • Skin aging such as dryness, roughness, dryness wrinkles, itching, decreased refatting (eg, after washing), visible vascular dilation (telangiectasia, cuperosis), slackness and wrinkle and wrinkle formation, localized hypersensitivity).
  • Hypo and false pigmentation eg, age spots
  • increased susceptibility to mechanical stress eg, cracking
  • they are advantageously suitable against the appearance of dry or rough skin.
  • the cosmetic preparations according to the invention may contain cosmetic adjuvants, such as are commonly used in such preparations, for.
  • cosmetic adjuvants such as are commonly used in such preparations, for.
  • Fillers that improve the feel on the skin, fats, oils, waxes or other common ingredients of a cosmetic or dermatological formulation such as alcohols, polyols, polymers, foam stabilizers, electrolytes, organic solvents or silicone derivatives.
  • the preparation according to the invention is in the form of an emulsion or hydrodispersion.
  • the preparation according to the invention is in the form of an emulsion.
  • the preparation is in the form of an O / W emulsion.
  • the preparation comprises one or more O / W emulsifiers selected from the group of the compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, ceteareth-20, PEG-40 stearate , Sodium cetearyl sulfate, Potassium cetyl phosphate, sodium stearoyl glutamate, sucrose polystearate, hydrogenated polyisobutenes.
  • O emulsifiers selected from the group of the compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, ceteareth-20, PEG-40 stearate , Sodium cetearyl sulfate, Potassium cet
  • these O / W emulsifiers according to the invention may advantageously be present in a concentration of from 0.001 to 10% by weight and preferably in a concentration of from 0.1 to 7% by weight, based on the total weight of the preparation.
  • Another embodiment of the present invention which is preferred according to the invention is characterized in that the preparation is in the form of a W / O emulsion.
  • the preparation contains one or more W / O emulsifiers selected from the group of the compounds polyglyceryl-2-dipolyhydroxystearate, PEG-30 dipolyhydroxystearate, cetyl dimethicone copolyol, polyglyceryl-3 diisostearate.
  • these W / O emulsifiers according to the invention may advantageously be present in a concentration of from 0.1 to 10% by weight and preferably in a concentration of from 0.2 to 7% by weight, based on the total weight of the preparation.
  • the test recipe was:
  • VP / hexadecene copolymer was incorporated into the fatty phase and the styrene / acrylate copolymer dispersion in the water phase.
  • the polymer concentration used was 10% active polymer in both cases.
  • VP / hexadecenes copolymer was present as pure substance, styrene / acrylate copolymer as dispersion with 46% solids content.
  • the in vitro water resistance test was carried out as follows:
  • the substrate for the test is an artificial skin model called Vitro Skin, which is distributed by the IMS Testing Group. It should be a matrix that contains both proteins and lipids and resembles the topography, pH and surface tension of human skin.
  • the substrate is cut into small pieces of 2.8 cm x 3.8 cm in size and then stored according to the manufacturer's instructions for 16-18 hours at a precisely set humidity in a humidity chamber.
  • the prepared substrate pieces are evenly creamed with 20 mg formulation and the pieces are clamped in commercially available slide frames.
  • the film former-free test formulation achieves an in vitro water resistance of 38.05%.
  • the film former VP / Hexadecene Copolymer currently used as standard in many sunscreen formulations achieved a waterfastness value of 48.69% at a use concentration of 10%, while with the styrene / acrylate copolymer "Joncryl 1532" it was 53.61% and the styrene / acrylate copolymer "Joncryl ECO2124" 83.13% could be achieved.

Abstract

The invention relates to a cosmetic preparation containing a) styrene/acrylate copolymers and b) one or more UV light filters.

Description

Beiersdorf Aktiengesellschaft Hamburg Beiersdorf Aktiengesellschaft Hamburg
Beschreibungdescription
Styrol/Acrylat-Copolymere in kosmetischen SonnenschutzmittelnStyrene / acrylate copolymers in cosmetic sunscreens
Die vorliegende Erfindung betrifft Styrol/Acrylat-Copolymere in kosmetischen Zubereitungen.The present invention relates to styrene / acrylate copolymers in cosmetic preparations.
Der Trend weg von der vornehmen Blässe hin zur „gesunden, sportlich braunen Haut" ist seit Jahren ungebrochen. Um diese zu erzielen setzen die Menschen ihre Haut der Sonnenstrahlung aus, da diese eine Pigmentbildung im Sinne einer Melaninbildung hervorruft. Die ultraviolette Strahlung des Sonnenlichtes hat jedoch auch eine schädigende Wirkung auf die Haut. Neben der akuten Schädigung (Sonnenbrand) treten Langzeitschäden wie ein erhöhtes Risiko an Hautkrebs zu erkranken bei übermäßiger Bestrahlung mit Licht aus dem UVB-Bereich (Wellenlänge: 280-320 nm) auf. Die übermäßige Einwirkung der UVB- und UVA- Strahlung (Wellenlänge: 320-400 nm) führt darüber hinaus zu einer Schwächung der elastischen und kollagenen Fasern des Bindegewebes. Dies führt zu zahlreichen phototoxischen und photoallergischen Reaktionen und hat eine vorzeitige Hautalterung zur Folge.The trend away from sophisticated paleness to "healthy, sporty brown skin" has been unbroken for years, and people are exposing their skin to sunlight, as it causes pigmentation in the sense of melanin formation, which has ultraviolet radiation from sunlight In addition to the acute injury (sunburn), long-term damage such as an increased risk of developing skin cancer due to excessive exposure to light from the UVB range (wavelength: 280-320 nm) occurs UVB and UVA radiation (wavelength: 320-400 nm) also leads to a weakening of the elastic and collagen fibers of the connective tissue, which leads to numerous phototoxic and photoallergic reactions and leads to premature aging of the skin.
Zum Schutz der Haut wurden daher eine Reihe von Lichtschutzfiltersubstanzen entwickelt, die in kosmetischen Zubereitungen eingesetzt werden können. Diese UVA- und UVB-Filter sind in den meisten Industrieländern in Form von Positivlisten wie der Anlage 7 der deutschen Kosmetikverordnung zusammengefasst.To protect the skin, therefore, a number of sunscreen filter substances have been developed which can be used in cosmetic preparations. These UVA and UVB filters are summarized in most industrialized countries in the form of positive lists such as Appendix 7 of the German Cosmetics Regulation.
Eine besondere Form von kosmetischen Sonnenschutzmitteln stellen die so genannten wasserfesten Sonnenschutzmittel dar.A special form of cosmetic sunscreen products are the so-called waterproof sunscreen.
Die meisten Sonnenschutzmittel werden in Wassernähe oder bei sportlicher Betätigung (Schwitzen) angewendet, weshalb der Wasserfestigkeit solcher Formulierungen eine besondere Bedeutung beizumessen ist. Ein wasserfestes Sonnenschutzmittel schützt den Anwender nicht nur nach dem Baden, sondern bewahrt ihn auch während des Badens vor einem Sonnenbrand.Most sunscreens are used near water or during exercise (sweating), which is why the water resistance of such formulations is of particular importance. A waterproof sunscreen protects the user not only after bathing, but also protects him during the bathing from sunburn.
Um hohe Lichtschutzfaktoren bei gleichzeitiger sehr guter Wasserfestigkeit zu erreichen, sind W/O-Formulierungen in der Regel von Vorteil. Allerdings weisen W/O-Emulsionen häufig unbefriedigende kosmetische Eigenschaften auf: Bei der Anwendung können sie auf der Haut einen fettigen, glänzenden und zum Teil klebrigen Eindruck hinterlassen und sich - insbesondere auf behaarter Haut - schwierig verteilen lassen.In order to achieve high sun protection factors with at the same time very good water resistance, W / O formulations are generally advantageous. However, W / O emulsions often have unsatisfactory cosmetic properties: when applied to the skin leave a greasy, shiny and sometimes sticky impression and - especially on hairy skin - difficult to distribute.
Viskose O/W-Emulsionen und dünnflüssige Sprays hingegen wirken weniger fettend auf der Haut, sind eher mattierend und ziehen schnell in die Haut ein. Sie werden vom Verbraucher im allgemeinen als leichter und kosmetisch eleganter als W/O-Emulsionen empfunden. Da Wasser die äußere Phase ist, sind O/W-Emulsionen gewöhnlich allerdings nur bedingt wasserfest.Viscose O / W emulsions and thin-bodied sprays, on the other hand, have less of a greasy effect on the skin, are rather mattifying and quickly penetrate the skin. They are generally perceived by consumers as lighter and more cosmetically elegant than W / O emulsions. However, since water is the outer phase, O / W emulsions are usually only partially waterproof.
Um die Wasserfestigkeit kosmetischer Sonnenschutzmittel zu verbessern, werden den Zubereitungen so genannte Filmbildner zugesetzt. Nach dem Stand der Technik eignen sich hierzu z. B. Polyurethane (z. B. die Avalure® -Typen von Goodrich), Dimethicone Copolyol Po- lyacrylate (Silsoft Surface® von der Witco Organo Silicones Group), PVP/VA (VA = Vinylacetat) Copolymer (Luviscol VA 64 Powder der BASF), C2o-4o Carbonsäure mit Polyethylen (Performacid 350 von der Fa. New Phase Technologies) sowie Filmbildner aus der Gruppe der Polymere auf Basis von Polyvinylpyrrolidon (PVP):In order to improve the water resistance of cosmetic sunscreen agents, so-called film formers are added to the preparations. According to the prior art, this z. Polyurethanes (eg the Avalure® grades from Goodrich), dimethicone copolyol polyacrylates (Silsoft Surface® from the Witco Organo Silicones Group), PVP / VA (VA = vinyl acetate) copolymer (Luviscol VA 64 Powder from BASF ), C 2 o- 4 o carboxylic acid with polyethylene (Performacid 350 from New Phase Technologies) and film formers from the group of polymers based on polyvinylpyrrolidone (PVP):
Figure imgf000003_0001
Figure imgf000003_0001
Besonders bevorzugt werden Copolymere des Polyvinylpyrrolidons eingesetzt, beispielsweise das PVP Hexadecen Copolymer und das PVP Eicosen Copolymer, welche unter den Handelsbezeichnungen Antaron V216 und Antaron V220 bei der GAF Chemicals Cooperation erhältlich sind, sowie das Tricontayl PVP und dergleichen mehr.Particular preference is given to using copolymers of polyvinylpyrrolidone, for example the PVP hexadecene copolymer and the PVP eicosene copolymer, which are available under the trade names Antaron V216 and Antaron V220 from the GAF Chemicals Cooperation, as well as the Tricontayl PVP and the like.
Nachteilig ist jedoch für derartige Zubereitungen, welche Filmbildner in einer wirksamen (d. h. die Wasserfestigkeit steigernden) Konzentration enthalten, dass sie bei der Anwendung auf der Haut einen klebrigen und schmierigen Eindruck hinterlassen. Darüber hinaus ist die Wasserfestigkeit und Schweißfestigkeit der Zubereitungen des Standes der Technik nur begrenzt. Aus diesem Grunde werden derartige Produkte auch regelmäßig mit dem Hinweis versehen, nach dem Baden erneut Sonnenschutzmittel auf die Haut aufzutragen. Für den Verbraucher hat dies den Nachteil, dass er, um einen effektiven UV-Schutz zu erhalten, einen erhöhten Verbrauch an Sonnenschutzmitteln hat. Für die Umwelt, insbesondere für das Badegewässer, besteht der Nachteil eines erhöhten Eintrags an Sonnenschutzmittel, was aus Umweltschutzgründen nicht immer erwünscht ist. Es war daher die Aufgabe der vorliegenden Erfindung, ein vor den UV-Strahlen der Sonne schützendes Kosmetikum zu entwickeln, welches eine gegenüber den Produkten des Standes -der Technik erhöhte Wasserfestigkeit und Schweißfestigkeit aufweist.A disadvantage, however, is for such preparations containing film former in an effective (ie increasing the water resistance) concentration that they leave a sticky and greasy impression when applied to the skin. In addition, the water resistance and weld strength of the prior art formulations is limited. For this reason, such products are also regularly provided with the note to apply sunscreen on the skin after bathing again. For the consumer, this has the disadvantage that, in order to obtain an effective UV protection, he has an increased consumption of sunscreen. For the environment, especially for the bathing water, there is the disadvantage of increased entry of sunscreen, which is not always desirable for environmental reasons. It was therefore the object of the present invention to develop a cosmetic which protects against the UV rays of the sun, which has a higher water resistance and perspiration resistance than the products of the prior art.
Es war ferner die Aufgabe der vorliegenden Erfindung, ein wasserfestes Sonnenschutzmittel zu entwickeln, dass in gegenüber dem Stand der Technik in reduzierter Menge an Filmbildner (bei gleichem Lichtschutzfaktor des Sonnenschutzmittels und bei gleichem Sonnenschutz für die Haut) eingesetzt werden kann.It was also the object of the present invention to develop a water-resistant sunscreen that can be used in relation to the prior art in a reduced amount of film former (with the same SPF of the sunscreen and the same sunscreen for the skin).
Darüber hinaus war es die Aufgabe der vorliegenden Erfindung, ein wasserfestesIn addition, it was the object of the present invention, a waterproof
Sonnenschutzmittel zu entwickeln, welches eine angenehme kosmetische Sensorik (nicht schmierig, leicht auf der Haut zu verteilen) aufweist.To develop sunscreen, which has a pleasant cosmetic sensory (not greasy, easy to distribute on the skin).
Neben dem Einfluss der Grundlage ist auch die Bindungsfähigkeit des UV-Filters in oder auf der Haut von großer Bedeutung für die Wasserfestigkeit der Formulierung. Es ist verständlich, dass öllösliche UV-Filter besser an die (lipophile) Oberfläche der Haut gebunden werden bzw. schwerer von dieser abwaschbar sind als wasserlösliche UV-Filter.In addition to the influence of the base, the binding ability of the UV filter in or on the skin is of great importance for the water resistance of the formulation. It is understandable that oil-soluble UV filters are better bound to the (lipophilic) surface of the skin or are more difficult to wash off this than water-soluble UV filters.
Eine weitere Aufgabe der Erfindung war es daher, auf einfache und preiswerte Weise zu Zu- bereitungen (insbesondere zu O/W-Formulierungen) zu gelangen, welche sich durch eine gute Wasserfestigkeit auszeichnen. Insbesondere sollten Zubereitungen gefunden werden, welche einen hohen Gehalt an wasserlöslichen UV-Filtern haben und dennoch eine sehr gute Wasserfestigkeit zeigen.A further object of the invention was therefore to arrive at preparations (in particular O / W formulations) in a simple and inexpensive manner, which are distinguished by good water resistance. In particular, preparations should be found which have a high content of water-soluble UV filters and nevertheless show a very good water resistance.
Überraschend gelöst werden die Aufgaben durch kosmetische Zubereitung enthaltend a) Styrol/Acrylat-Copolymere und b) ein oder mehrere UV-Lichtschutzfilter.The objects are surprisingly achieved by cosmetic preparation comprising a) styrene / acrylate copolymers and b) one or more UV light protection filters.
Erfindungsgemäß ist ferner die Verwendung von Styrol/Acrylat-Copolymeren zur Erhöhung der Wasserfestigkeit von kosmetischen Sonnenschutzmitteln.The invention also relates to the use of styrene / acrylate copolymers to increase the water resistance of cosmetic sunscreens.
Erfindungsgemäß ist außerdem die Verwendung von Styrol/Acrylat-Copolymeren zur Erhöhung der Schweißfestigkeit von kosmetischen Sonnenschutzmitteln.The invention also provides the use of styrene / acrylate copolymers to increase the perspiration resistance of cosmetic sunscreens.
Zwar kennt der Fachmann die WO 01/54660, welche eine Zubereitung mit dem Styren/Acrylat- Copolymer „Joncryl® 77" (welches eine Glasübergangstemperatur von T9= 35CC aufweist) offenbart, doch konnte diese Schrift u.a. deshalb nicht den Weg zur vorliegenden Erfindung weisen, weil es sich nicht um ein Sonnenschutzmittel handelt, die Zubereitung als besonders glänzend (und damit optisch wenig attraktiv) sowie als brüchig (d.h. als schwer homogen und stabil formulierbar) charakterisiert wird.While the skilled artisan knows WO 01/54660, which (having a glass transition temperature T 9 = 35 C C has) discloses a preparation with the styrene / acrylate copolymer "Joncryl ® 77", this specification was among other reasons not the way to The present invention, because it is not a sunscreen, the preparation especially shiny (and thus visually less attractive) and as brittle (ie, difficult to form homogeneous and stable formulatable) is characterized.
Darüber hinaus kennt der Fachmann die EP 1101488, die ebenfalls nicht den Weg zur vorliegenden Erfindung weisen konnte.In addition, the skilled person knows the EP 1101488, which also could not point the way to the present invention.
Die erfindungsgemäßen Zubereitungen sind einfach und preisgünstig herstellbar.The preparations according to the invention can be prepared simply and inexpensively.
Es ist erfindungsgemäß besonders vorteilhaft, wenn die erfindungsgemäßen Styrol/Acrylat- Copolymere eine Glasübergangstemperatur von kleiner oder gleich 20 0C aufweisen. DieIt is inventively particularly advantageous if the styrene / acrylate copolymers according to the invention have a glass transition temperature of less than or equal to 20 0 C. The
Glasübergangstemperatur wird dabei erfindungsgemäß wie folgt gemessen: Verwendet wurde das Messgerät „DSC 822e" der Firma Mettler, die Probe wurde in einen gelochten 40μl Aluminium-Tiegel eingefüllt. Erfasst wurde der Temperaturbereich von -1400C bis +1500C1 Heizrate 10°C/min, gemessen wurde über zwei Temperaturzyklen, zur Auswertung wurde die zweite Aufheizkurve herangezogen.Glass transition temperature is measured according to the invention as follows: The meter "DSC 822e" was used Mettler, the sample was filled in a perforated 40 .mu.l aluminum crucible has been detected in the temperature range from -140 0 C to +150 0 C 1 heating rate 10 °. C / min, was measured over two temperature cycles, for evaluation, the second heating curve was used.
Wie sich aus dem Vergleichsversuch (siehe unten) ergibt, ist die Wasserfestigkeit bei derartigen Copolymeren überraschend hoch.As can be seen from the comparative experiment (see below), the water resistance in such copolymers is surprisingly high.
Erfindungsgemäß vorteilhaft wird das erfindungsgemäße Copolymer aus den folgenden Monomeren aufgebaut:According to the invention, the copolymer according to the invention is advantageously built up from the following monomers:
(a) Styren und daraus abgeleitete Verbindungen(a) Styrene and compounds derived from it
(b) Acrylsäure und/oder Methacrylsäure und/oder Verbindungen mit der Struktur H2C=CR1Y, wobei R1 für Wasserstoff oder Methyl steht und Y sowohl -COOR2als auch COO X+ bedeutet. R2 steht dabei für geradkettige oder verzweigte Alkylgruppen, geradkettige oder verzweigte Alkylengruppen, die jeweils auch substituiert sein können.(b) acrylic acid and / or methacrylic acid and / or compounds having the structure H 2 C = CR 1 Y, where R 1 is hydrogen or methyl and Y is both -COOR 2 and COO X + . R 2 stands for straight-chain or branched alkyl groups, straight-chain or branched alkylene groups, each of which may also be substituted.
X+ bezeichnet Lithium-, natrium-, Kalium-, Magnesium-, Calcium-, Aluminium-, Ammonium-, Mono-/Di-/Tri/ und Tetraalkylammoniumionen.X + denotes lithium, sodium, potassium, magnesium, calcium, aluminum, ammonium, mono- / di- / tri and tetraalkylammonium ions.
Erfindungsgemäß bevorzugt sind Copolymere aus Acrylatmonomeren, Methacrylatmonomeren, Acrylsäure, Methacrylsäure und Styrol.Copolymers of acrylate monomers, methacrylate monomers, acrylic acid, methacrylic acid and styrene are preferred according to the invention.
Die erfindungsgemäßen Styrol/Acrylat-Copolymere sind beispielsweise unter den Handelsnamen Joncryl 1532 und Joncryl ECO 2124 bei der Firma BASF Resins erhältlich.The styrene / acrylate copolymers according to the invention are obtainable, for example, under the trade names Joncryl 1532 and Joncryl ECO 2124 from BASF Resins.
Erfindungsgemäß besonders bevorzugt sind Copolymere aus Styrol, 2-ethylhexylacrylat, butylcrylat, methylmethacrylate und Acrylsäure (z.B. Joncryl ECO 2124) sowie Copolymere aus Sytrol, 2-ethylhexylacrylat, Isobutylcrylat, methylmethacrylate, butylacrylat, Acrylsäure, Methacrylsäure (z.B. Joncryl 1532).Especially preferred according to the invention are copolymers of styrene, 2-ethylhexyl acrylate, butyl acrylate, methyl methacrylate and acrylic acid (eg Joncryl ECO 2124) and also copolymers Sytrol, 2-ethylhexyl acrylate, isobutyl acrylate, methyl methacrylate, butyl acrylate, acrylic acid, methacrylic acid (eg Joncryl 1532).
Erfindungsgemäß vorteilhaft ist es, wenn die erfindungsgemäße Zubereitung Styrol/Acrylat- Copolymer in einer Konzentration von 0,1 bis 30 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.It is advantageous according to the invention if the preparation according to the invention contains styrene / acrylate copolymer in a concentration of 0.1 to 30% by weight, based on the total weight of the preparation.
Erfindungsgemäß bevorzugt ist es, wenn die erfindungsgemäße Zubereitung Styrol/Acrylat- Copolymer in einer Konzentration von 0,5 bis 15 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.It is preferred according to the invention if the preparation according to the invention contains styrene / acrylate copolymer in a concentration of 0.5 to 15% by weight, based on the total weight of the preparation.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Zubereitung UV- Lichtschutzfilter in einer Gesamtmenge von 0,2 bis 40 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.It is advantageous according to the invention if the preparation according to the invention contains UV light protection filters in a total amount of from 0.2 to 40% by weight, based on the total weight of the preparation.
Es ist erfindungsgemäß bevorzugt, wenn die erfindungsgemäße Zubereitung UV- Lichtschutzfilter in einer Gesamtmenge von 0,5 bis 30 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.It is preferred according to the invention if the preparation according to the invention contains UV light protection filters in a total amount of from 0.5 to 30% by weight, based on the total weight of the preparation.
Es ist erfindungsgemäß vorteilhaft, wenn die UV-Lichtschutzfilter gewählt werden aus derIt is inventively advantageous if the UV light protection filters are selected from the
Gruppe der Verbindungen Phenylen-1 ,4-bis-(2-benzimidazyl)-3,3'-5,5'-tetrasulfonsäure und ihre Salze; 2-Phenylbenzimidazol-5-su!fonsäuresalze; 1 ,4-di(2-oxo-10-Sulfo-3-bornylidenmethyl)- Benzol und dessen Salze; 4-(2-Oxo-3-bornylidenmethyl)benzolsulfonsäuresalze; 2-Methyl-5-(2- oxo-3-bornylidenmethyl)sulfonsäure und ihre Salze; 2,2'-Methylen-bis-(6-(2H-benzotriazol-2-yl)- 4-(1 ,1 ,3,3-tetramethylbutyl)-phenol); 2-(2H-benzotriazol-2-yl)-4-methyl-6-[2-methyl-3-[1 ,3,3,3- tetramethyl-1-[(trimethylsilyl)oxy]disiloxanyl]propyl]-phenol; 3-(4-Methylbenzyliden)campher; 3- Benzylidencampher; Ethylhexylsalicylat; Terephthalidendicamphersulfonsäure; A- (Dimethylamino)-benzoesäure(2-ethylhexyl)ester; 4-(Dimethylamino)benzoesäure-amylester; A- Methoxybenzalmalon-säuredi(2-ethylhexyl)ester; 4-Methoxyzimtsäure(2-ethylhexyl)ester; A- Methoxyzimtsäureisoamylester; 2-Hydroxy-4-methoxybenzophenon, 2-Hydroxy-4-methoxy-4'- methylbenzophenon; 2,2'-Dihydroxy-4-methoxybenzophenon; 2-(4'-Diethylamino-2'- hydoxybenzoyl)-benzoesäurehexylester, 4-(tert.-Butyl)-4'-methoxydibenzoylmethan; Homomenthylsalicylat; 2-Ethylhexyl-2-hydroxybenzoat; 2-Ethylhexyl-2-cyano-3,3-diphenyl- acrylat; Dimethicodiethylbenzalmalonat; 3-(4-(2,2-bis Ethoxycarbonylvinyl)-phenoxy)propenyl)- methoxysiloxan / Dimethylsiloxan - Copolymer; 2,4-Bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]- phenyl}-6-(4-methoxyphenyl)-1 ,3,5-triazin (INCI :Bis-Ethylhexyloxyphenol Methoxyphenyl Triazin).; Dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone); 2,4-bis-[5-1(dimethyl- propyl)benzoxazol-2-yl-(4-phenyl)-imino]-6-(2-ethylhexyl)-imino-1 ,3,5-triazin mit der (CAS Nr. 288254-16-0); 4,4',4"-( 113,5-Triazin-2,4,6-triyltriimino)-tris-benzoesäure-tris(2-ethylhexylester) (auch: 2,4l6-Tris-[anilino-(p-carbo-2'-ethyl-1l-hexyloxy)]-1 ,3,5-triazin (INCI: Ethylhexyl Triazone); -2,4,6-Tribiphenyl-4-yl-1 ,3,5-triazin; Hydroxyphenylbenzophenon; Merocyanine; Titiandioxid; Zinkoxid.Group of compounds phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonic acid and its salts; ! 2-phenyl-5-su fonsäuresalze; 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl) benzene and its salts; 4- (2-oxo-3-bornylidenemethyl) benzenesulfonic acid; 2-methyl-5- (2-oxo-3-bomylidenemethyl) sulfonic acid and its salts; 2,2'-methylenebis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) phenol); 2- (2H-Benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] phenol ; 3- (4-methylbenzylidene) camphor; 3-benzylidene camphor; ethylhexyl salicylate; Terephthalidendicamphersulfonsäure; A- (dimethylamino) -benzoic acid (2-ethylhexyl) ester; 4- (dimethylamino) benzoic acid amyl ester; 2-ethylhexyl A-methoxybenzalmalonate di (2-ethylhexyl); 4-methoxycinnamate (2-ethylhexyl) ester; A-methoxycinnamic acid isoamyl ester; 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone;2,2'-dihydroxy-4-methoxybenzophenone; Hexyl 2- (4'-diethylamino-2'-hydroxybenzoyl) benzoate, 4- (tert-butyl) -4'-methoxydibenzoylmethane;homomenthyl; 2-ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl-2-cyano-3,3-diphenylacrylate; dimethicodiethylbenzalmalonate; 3- (4- (2,2-ethoxycarbonylvinyl) phenoxy) propenyl) methoxysiloxane / dimethylsiloxane copolymer; 2,4-Bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI: bis-ethylhexyloxyphenol methoxyphenyl triazine) . Dioctylbutylamidotriazone (INCI: diethylhexyl-butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -6- (2-ethylhexyl) -imino-1,3,5-triazine with the CAS no. 288254-16-0); 4,4 ', 4 "- (1 1 3,5-triazine-2,4,6-triyltriimino) tris-benzoic acid tris (2-ethylhexyl ester) (also: 2.4 l of 6-tris [anilino] (p-carbo-2'-ethyl-1 l -hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone); -2,4,6-tribiphenyl-4-yl-1,3,5- triazine; hydroxyphenylbenzophenone; merocyanines; titanium dioxide; zinc oxide.
Die Pigmente (Titandioxid, Zinkoxid) können erfindungsgemäß vorteilhaft oberflächlich behandelt („gecoatet") sein, wobei beispielsweise ein hydrophiler, amphiphiler oder hydrophober Charakter gebildet werden bzw. erhalten bleiben soll. Diese Oberflächenbehandlung kann darin bestehen, dass die Pigmente nach an sich bekannten Verfahren mit einer dünnen hydrophilen und/oder hydrophoben anorganischen und/oder organischen Schicht versehen werden. Die verschiedenen Oberflächenbeschichtungen können im Sinne der vorliegenden Erfindung auch Wasser enthalten.According to the invention, the pigments (titanium dioxide, zinc oxide) can advantageously be surface-treated ("coated"), in which case for example a hydrophilic, amphiphilic or hydrophobic character is to be formed or is to be retained.This surface treatment can consist in that the pigments are prepared by processes known per se be provided with a thin hydrophilic and / or hydrophobic inorganic and / or organic layer.The various surface coatings may also contain water for the purposes of the present invention.
Anorganische Oberflächenbeschichtungen im Sinne der vorliegenden Erfindung können be- stehen aus Aluminiumoxid (AI2O3), Aluminiumhydroxid AI(OH)3, bzw. Aluminiumoxidhydrat (auch: Alumina, CAS-Nr.: 1333-84-2), Natriumhexametaphosphat (NaPO3J6, Natriummeta- phösphat (NaPO3)n, Siliciumdioxid (SiO2) (auch: Silica, CAS-Nr.: 7631-86-9), Bariumsulfat (BaSO4) oder Eisenoxid (Fe2O3). Diese anorganischen Oberflächenbeschichtungen können allein, in Kombination und/oder in Kombination mit organischen Beschichtungsmaterialien vor- kommen.Inorganic surface coatings for the purposes of the present invention may consist of aluminum oxide (Al 2 O 3 ), aluminum hydroxide Al (OH) 3 or aluminum oxide hydrate (also: Alumina, CAS No .: 1333-84-2), sodium hexametaphosphate (NaPO 3 J 6 , sodium metaphosphate (NaPO 3 ) n , silicon dioxide (SiO 2 ) (also: silica, CAS No .: 7631-86-9), barium sulfate (BaSO 4 ) or iron oxide (Fe 2 O 3 ) Inorganic surface coatings may occur alone, in combination and / or in combination with organic coating materials.
Organische Oberflächenbeschichtungen im Sinne der vorliegenden Erfindung können bestehen aus pflanzlichem oder tierischem Aluminiumstearat, pflanzlicher oder tierischer Stearinsäure, Laurinsäure, Dimethylpolysiloxan (auch: Dimethicone), Methylpolysiloxan (Methicone), Simethi- cone (einem Gemisch aus Dimethylpolysiloxan mit einer durchschnittlichen Kettenlänge von 200 bis 350 Dimethylsiloxan-Einheiten und Silicagel) oder Alginsäure. Diese organischen Oberflächenbeschichtungen können allein, in Kombination und/oder in Kombination mit anorganischen Beschichtungsmaterialien vorkommen.Organic surface coatings for the purposes of the present invention may consist of vegetable or animal aluminum stearate, vegetable or animal stearic acid, lauric acid, dimethylpolysiloxane (also: dimethicone), methylpolysiloxane (methicone), simethicone (a mixture of dimethylpolysiloxane with an average chain length of 200 to 350 Dimethylsiloxane units and silica gel) or alginic acid. These organic surface coatings may be present alone, in combination and / or in combination with inorganic coating materials.
Erfindungsgemäß bevorzugt ist dabei der Einsatz von Triazinen, 4-(tert.-Butyl)-4'-methoxydi- benzoylmethan, 4-Methoxyzimtsäure(2-ethylhexyl)ester; 2-Ethylhexyl-2-cyano-3,3-diphenyl- acrylat, Titandioxid.Preference according to the invention is given to the use of triazines, 4- (tert-butyl) -4'-methoxydibenzoylmethane, 4-methoxycinnamic acid (2-ethylhexyl) ester; 2-ethylhexyl-2-cyano-3,3-diphenyl-acrylate, titanium dioxide.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Zubereitung frei ist von p- Methylbenzylidencampher.It is advantageous according to the invention if the preparation according to the invention is free of p-methylbenzylidene camphor.
Es ist erfindungsgemäß vorteilhaft, wenn die Zubereitung als weitere Inhaltsstoffe eine oder mehrere Verbindungen gewählt aus der Gruppe der Verbindungen alpha-Liponsäure, Folsäure, Phytoen, D-Biotin, Coenzym Q10, alpha-Glucosylrutin, Carπitin, Carnosin, Polydocanol, natürliche und/oder synthetische Isoflavonoide, Flavonoide, Kreatin, Kreatinin, Taurin, ß-Alanin, Tocopherylacetat, Harnstoff; Hyaluronsäure; Dihydroxyaceton; 8-Hexadecen-1,16-dicarbon- säure und/oder Licochalcon A enthält.It is advantageous according to the invention if the preparation contains, as further ingredients, one or more compounds selected from the group of the compounds alpha-lipoic acid, folic acid, Phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carbitin, carnosine, polydocanol, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, ß-alanine, tocopheryl acetate, urea; hyaluronic acid; dihydroxyacetone; 8-hexadecene-1,16-dicarboxylic acid and / or licochalcone A contains.
Diese Inhaltsstoffe werden erfindungsgemäß bevorzugt in einer Einzelkonzentration von 0,001 bis 5 Gew:-%, bezogen auf das Gesamtgewicht der Zubereitung, eingesetzt.These ingredients are preferably used according to the invention in a single concentration of 0.001 to 5% by weight, based on the total weight of the preparation.
Erfindungsgemäß vorteilhafte Zubereitungen lassen sich auch dadurch erhalten, dass die erfindungsgemäße Zubereitung ein oder mehrere Verbindungen gewählt aus der Gruppe der Parabene, Phenoxyethanol, Ethylhexylglycerin, 2-Methylpropan-1 ,3-diol, Butylenglycol, Propylenglycol enthält.Preparations which are advantageous according to the invention can also be obtained by the preparation according to the invention containing one or more compounds selected from the group consisting of parabens, phenoxyethanol, ethylhexylglycerol, 2-methylpropane-1,3-diol, butylene glycol, propylene glycol.
Diese Inhaltsstoffe werden erfindungsgemäß bevorzugt in einer Einzelkonzentration von 0,001 bis 5 Gew:-%, bezogen auf das Gesamtgewicht der Zubereitung, eingesetzt.These ingredients are preferably used according to the invention in a single concentration of 0.001 to 5% by weight, based on the total weight of the preparation.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Zubereitung eine Viskosität von 100 bis 20 000 mPaS aufweist. Erfindungsgemäß bevorzugt ist dabei eine Viskosität von 300 bis 10000 mPaS, gemessen jeweils mit dem Meßgerät: Haake Viskotester VT-02 bei 25 0C.It is advantageous according to the invention if the preparation according to the invention has a viscosity of 100 to 20,000 mPaS. According to the invention is a viscosity from 300 to 10,000 mPas, measured in each case with the measuring device: Haake Viscotester VT-02 at 25 0 C.
Ferner vorteilhaft können die erfindungsgemäßen Zubereitungen auch Repellenten zum Schutz vor Mücken, Zecken und Spinnen und dergleichen enthalten. Vorteilhaft sind z. B. N,N-Diethyl- 3-methylbenzamid (Handelsbezeichnung: Meta-delphene, „DEET"), Dimethylphtalat (Handelsbezeichnung: Palatinol M, DMP), 1-Piperidincarbonsäure-2-(2-hydroxyethyl)-1- methylpropylester sowie insbesondere 3-(N-n-Butyl-N-acetyl-amino)-propionsäureethylester (unter dem Handelsnamen Insekt Repellent® 3535 bei der Fa. Merck erhältlich). Die Repellenten können sowohl einzeln als auch in Kombination eingesetzt werden.Furthermore, the preparations according to the invention may also advantageously contain repellents for protection against mosquitoes, ticks and spiders and the like. Advantageous z. N, N-diethyl-3-methylbenzamide (trade name: Meta-delphene, "DEET"), dimethyl phthalate (trade name: Palatinol M, DMP), 1-piperidinecarboxylic acid 2- (2-hydroxyethyl) -1-methylpropyl ester, and especially 3- (Nn-butyl-N-acetyl-amino) -propionic acid ethyl ester (available commercially from Merck under the tradename Insekt Repellent® 3535.) The repellents can be used either singly or in combination.
Als Feuchthaltemittel (Moisturizer) werden Stoffe oder Stoffgemische bezeichnet, welche kosmetischen Zubereitungen die Eigenschaft verleihen, nach dem Auftragen bzw. Verteilen auf der Hautoberfläche die Feuchtigkeitsabgabe der Hornschicht (auch transepidermal water loss (TEWL) genannt) zu reduzieren und/oder die Hydratation der Hornschicht positiv zu beeinflussen.Moisturizers are substances or mixtures of substances which give cosmetic preparations the property of reducing the moisture release of the horny layer (also called transepidermal water loss (TEWL) after application or spreading on the skin surface) and / or hydrating the horny layer positively influence.
Vorteilhafte Feuchthaltemittel (Moisturizer) im Sinne der vorliegenden Erfindung sind beispielsweise Glycerin, Milchsäure und/oder Lactate, insbesondere Natriumlactat, Butylenglyko!, Propylenglykol, Biosaccaride Gum-1 , Glycine Soja, Ethylhexyloxyglycerin, Pyrrolidoncarbonsäure und Harnstoff. Ferner ist es insbesondere von Vorteil, polymere Moisturizer aus der Gruppe der wasserlöslichen und/oder in Wasser quellbaren und/oder mit Hilfe von Wasser gelierbaren Polysaccharide zu verwenden. Insbesondere vorteilhaft sind •beispielsweise Hyaluronsäure, Chitosan und/oder ein fucosereiches Polysaccharid, welches in den Chemical Abstracts unter der Registraturnummer 178463-23-5 abgelegt und z. B. unter der Bezeichnung Fucogel®1000 von der Gesellschaft SOLABIA S.A. erhältlich ist. Moisturizer können vorteilhaft auch als Antifaltenwirkstoffe zum Schutz vor Hautveränderungen, wie sie z. B. bei der Hautalterung auftreten, verwendet werden.Advantageous humectants (moisturizers) for the purposes of the present invention are, for example, glycerol, lactic acid and / or lactates, in particular sodium lactate, butylene glycol, propylene glycol, biosaccharide gum-1, glycine soya, ethylhexyloxyglycerol, pyrrolidonecarboxylic acid and urea. Furthermore, it is particularly advantageous to use polymers Moisturizer from the group of water-soluble and / or water-swellable and / or water-gelable polysaccharides to use. Particularly advantageous are, for example, hyaluronic acid, chitosan and / or a fucose-rich polysaccharide, which are filed in the Chemical Abstracts under the registry number 178463-23-5 and z. B. under the name Fucogel®1000 of the company SOLABIA SA is available. Moisturizers can also be used advantageously as anti-wrinkle active ingredients for protection against skin changes, as described, for example, in US Pat. B. occur during skin aging, can be used.
Es ist vorteilhaft im Sinne der vorliegenden Erfindung, wenn die erfindungsgemäße Zubereitung ein oder mehrere Feuchthaltemittel in einer Gesamtkonzentration von 0,1 bis 20 Gewichts-% und bevorzugt in einer Gesamtkonzentration von 0,5 bis 10 Gewichts-%, jeweils bezogen auf das Gesamtgewicht der Zubereitung, enthält.It is advantageous for the purposes of the present invention, when the inventive preparation one or more humectants in a total concentration of 0.1 to 20% by weight and preferably in a total concentration of 0.5 to 10% by weight, each based on the total weight of Preparation containing.
Die erfindungsgemäßen kosmetischen Zubereitungen können ferner vorteilhaft, wenngleich nicht zwingend, Füllstoffe enthalten, welche z. B. die sensorischen und kosmetischenThe cosmetic preparations according to the invention may also advantageously, although not necessarily, contain fillers which are e.g. B. the sensory and cosmetic
Eigenschaften der Formulierungen weiter verbessern und beispielsweise ein samtiges oder seidiges Hautgefühl hervorrufen oder verstärken. Vorteilhafte Füllstoffe im Sinne der vorliegenden Erfindung sind Stärke und Stärkederivate (wie z. B. Tapiocastärke, Distärkephosphat, Aluminium- bzw. Natrium-Stärke Octenylsuccinat und dergleichen), Pigmente, die weder hauptsächlich UV-Filter- noch färbende Wirkung haben (wie z. B. Bornitrid etc.) und/oder Aerosile® (CAS-Nr. 7631-86-9) und /oder Talkum.Further improve the properties of the formulations and, for example, cause or enhance a velvety or silky feel on the skin. Advantageous fillers for the purposes of the present invention are starch and starch derivatives (such as, for example, tapioca starch, distarch phosphate, aluminum or sodium starch, octenylsuccinate and the like), pigments which have neither mainly UV filter nor coloring action (such as, for example, US Pat. B. boron nitride etc.) and / or Aerosils ® (CAS no. 7631-86-9) and / or talc.
Die Wasserphase der erfindungsgemäßen Zubereitungen kann vorteilhaft übliche kosmetische Hilfsstoffe enthalten, wie beispielsweise Alkohole, insbesondere solche niedriger C-Zahl, vorzugsweise Ethanol und/oder Isopropanol, Diole oder Polyole niedriger C-Zahl sowie deren Ether, vorzugsweise Propylenglykol, 2-Methylpropan-1 ,3-diol, Glycerin, Ethylenglykol, Ethylen- glykolmonoethyl- oder -monobutylether, Propylenglykolmonomethyl, -monoethyl- oder -monobu- tylether, Diethylenglykolmonomethyl- oder -monoethylether und analoge Produkte, Polymere, Schaumstabilisatoren, Elektrolyte, Selbstbräuner.The aqueous phase of the preparations according to the invention may advantageously comprise customary cosmetic auxiliaries, for example alcohols, in particular those of low C number, preferably ethanol and / or isopropanol, diols or polyols of low C number and their ethers, preferably propylene glycol, 2-methylpropane-1, 3-diol, glycerol, ethylene glycol, ethylene glycol monoethyl or monobutyl ether, propylene glycol monomethyl, monoethyl or monobutyl ether, diethylene glycol monomethyl or monoethyl ether and analogous products, polymers, foam stabilizers, electrolytes, self-tanning agents.
Die erfindungsgemäße Zubereitung kann neben dem erfindungsgemäßen Copolymer auch weitere Polymere enthalten, beispielsweise Polysaccharide bzw. deren Derivate, z. B. Hyaluronsäure, Xanthangummi, Hydroxypropylmethylcellulose, Polyacrylate (hier beispielsweise Carbopole der Typen 980, 981 , 1382, 2984, 5984, jeweils einzeln oder in Kombination). Weitere Polymere sind solche mit der INCI-Bezeichnung Acrylates/C 10-30 Alkyl Acrylate Crosspolymer (z. B. Pemulen TR 1 , Pemulen TR 2, Carbopol 1382 von der Fa. NOVEON), Aristoflex AVC (INCI: Ammonium Acryloyldimethyltaurate/VP Copolymer), sowie Acrylic Acid/VP Crosspolymer (Ultrathix P-100, ISP). Die Ölphase der erfindungsgemäßen Zubereitung wird vorteilhaft gewählt aus der Gruppe der -polaren Öle, beispielsweise aus der Gruppe der Lecithine und der Fettsäuretriglyceride, namentlich der Triglycerinester gesättigter und/oder ungesättigter, verzweigter und/oder unver- zweigter Alkancarbonsäuren einer Kettenlänge von 8 bis 24, insbesondere 12 bis 18 C-Atomen. Die Fettsäuretriglyceride können beispielsweise vorteilhaft gewählt werden aus der Gruppe der synthetischen, halbsynthetischen und natürlichen Öle, wie z. B. Cocoglycerid, Olivenöl, Sonnenblumenöl, Jojobaöl, Sojaöl, Erdnußöl, Rapsöl, Mandelöl, Palmöl, Kokosöl, Rizinusöl, Weizenkeimöl, Traubenkemöl, Distelöl, Nachtkerzenöl, Macadamianußöl und dergleichen mehr.The preparation of the invention, in addition to the copolymer according to the invention also contain other polymers, for example polysaccharides or their derivatives, for. As hyaluronic acid, xanthan gum, hydroxypropylmethylcellulose, polyacrylates (here, for example, Carbopols types 980, 981, 1382, 2984, 5984, each individually or in combination). Further polymers are those with the INCI name Acrylates / C 10-30 alkyl acrylate crosspolymer (eg Pemulen TR 1, Pemulen TR 2, Carbopol 1382 from the company NOVEON), Aristoflex AVC (INCI: ammonium acryloyldimethyltaurate / VP copolymer ), as well as Acrylic Acid / VP Crosspolymer (Ultrathix P-100, ISP). The oil phase of the preparation according to the invention is advantageously selected from the group of polar oils, for example from the group of lecithins and fatty acid triglycerides, namely the triglycerol esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of from 8 to 24, in particular 12 to 18 carbon atoms. The fatty acid triglycerides can be selected, for example, advantageously from the group of synthetic, semi-synthetic and natural oils, such as. Cocoglyceride, olive oil, sunflower oil, jojoba oil, soybean oil, peanut oil, rapeseed oil, almond oil, palm oil, coconut oil, castor oil, wheat germ oil, grape seed oil, thistle oil, evening primrose oil, macadamia nut oil and the like.
Erfindungsgemäß vorteilhaft sind ferner z. B. natürliche Wachse tierischen und pflanzlichen Ursprungs, wie beispielsweise Bienenwachs und andere Insektenwachse sowie Beerenwachs, Sheabutter und/oder Lanolin (Wollwachs).Also advantageous according to the invention are z. As natural waxes of animal and vegetable origin, such as beeswax and other insect waxes and berry wax, shea butter and / or lanolin (wool wax).
Weitere vorteilhafte polare Ölkomponenten können im Sinne der vorliegenden Erfindung ferner gewählt werden aus der Gruppe der Ester aus gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkancarbonsäuren einer Kettenlänge von 3 bis 30 C-Atomen und gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkoholen einer Kettenlänge von 3 bis 30 C-Atomen sowie aus der Gruppe der Ester aus aromatischen Carbonsäuren und gesättigten und/oder ungesättigten, verzweigten und/oder unverzweigten Alkoholen einer Kettenlänge von 3 bis 30 C-Atomen. Solche Esteröle können dann vorteilhaft gewählt werden aus der Gruppe Phenethylbenzoat, 2-Phenylethylbenzoat, Isopropyl Lauroyl Sarkosinat, Phenyl Trimethicon, Cyclomethicon, Dibutyladipat, Octylpalmitat, Octylcocoat, Octylisostearat, Octyldodeceylmyristat, Octyldodekanol, Cetearylisononanoat, Isopropylmyristat, Isopropylpalmi- tat, Isopropylstearat, Isopropyloleat, n-Butylstearat, n-Hexyllaurat, n-Decyloleat, Isooctylstearat, Isononylstearat, Isononylisononanoat, 2-Ethylhexylpalmitat, 2-Ethylhexyllaurat, 2-Hexyldecyl- stearat, 2-Octyldodecylpalmitat, Stearylheptanoat, Oleyloleat, Oleylerucat, Erucyloleat, Eru- cylerucat, Tridecylstearat, Tridecyltrimellitat, sowie synthetische, halbsynthetische und natürliche Gemische solcher Ester, wie z. B. Jojobaöl.In the context of the present invention, further advantageous polar oil components can furthermore be selected from the group of esters of saturated and / or unsaturated, branched and / or unbranched alkanecarboxylic acids having a chain length of 3 to 30 carbon atoms and saturated and / or unsaturated, branched and / or or unbranched alcohols having a chain length of 3 to 30 carbon atoms and from the group of esters of aromatic carboxylic acids and saturated and / or unsaturated, branched and / or unbranched alcohols having a chain length of 3 to 30 carbon atoms. Such ester oils can then advantageously be selected from the group consisting of phenethyl benzoate, 2-phenylethyl benzoate, isopropyl lauroyl sarcosinate, phenyl trimethicone, cyclomethicone, dibutyl adipate, octyl palmitate, octyl cocoate, octyl isostearate, octyldodeceyl myristate, octyldodecanol, cetearyl isononanoate, isopropyl myristate, isopropyl palmitate, isopropyl stearate, isopropyl oleate, n Butyl stearate, n-hexyl laurate, n-decyl oleate, isooctyl stearate, isononyl stearate, isononyl isononanoate, 2-ethylhexyl palmitate, 2-ethylhexyl laurate, 2-hexyldecyl stearate, 2-octyldodecyl palmitate, stearylheptanoate, oleyl oleate, oleyl erucate, erucyl oleate, erucylerucate, tridecyl stearate, tridecyl trimellitate , as well as synthetic, semi-synthetic and natural mixtures of such esters, such as. B. jojoba oil.
Ferner kann die Ölphase vorteilhaft gewählt werden aus der Gruppe der Dialkylether und Dialkylcarbonate, vorteilhaft sind z. B. Dicaprylylether (Cetiol OE) und/oder Dicaprylylcarbonat, beispielsweise das unter der Handelsbezeichnung Cetiol CC bei der Fa. Cognis erhältliche.Furthermore, the oil phase can be advantageously selected from the group of dialkyl ethers and dialkyl carbonates, advantageous z. B. dicaprylyl ether (Cetiol OE) and / or dicaprylyl, for example, that available under the trade name Cetiol CC in the company. Cognis.
Es ist ferner bevorzugt, das oder die Ölkomponenten aus der Gruppe Isoeikosan, Neopen- tylglykoldiheptanoat, Propylenglykoldicaprylat/dicaprat, Caprylic/Capric/Diglycerylsuccinat, Butylenglykol Dicaprylat/Dicaprat, C12-i3-Alkyllactat, Di-C12-i3-Alkyltartrat, Triisostearin, Dipenta- er/thrityl Hexacaprylat/Hexacaprat, Propylenglykolmonoisostearat, Tricaprylin, Dimethyϊiso- sorbid, Myristylmyristat, Isodecylneopentanoat. Es ist insbesondere vorteilhaft, wenn die Ölphase der erfindungsgemäßen Formulierungen einen Gehalt an C12-15-Alkylbenzoat aufweist oder vollständig aus diesem besteht.It is further preferred that the oil component from the group consisting of isoeicosane, neopentyl tylglykoldiheptanoat, dicaprylate / dicaprate propylene glycol, caprylic / capric / diglyceryl succinate, butylene glycol dicaprylate / dicaprate, C 12 -i 3 alkyl lactate, di-C 12-i 3 -Alkyltartrat , Triisostearin, dipentamer / thrityl hexacaprylate / hexacaprate, propylene glycol monoisostearate, tricaprylin, dimethyisiso- sorbid, myristyl myristate, isodecyl neopentanoate. It is particularly advantageous if the oil phase of the formulations according to the invention has a content of C 12-15 -alkyl benzoate or consists entirely of this.
Vorteilhafte Ölkomponenten sind ferner z. B. Butyloctylsalicylat (beispielsweise das unter der Handelsbezeichnung Hallbrite BHB bei der Fa. CP Hall erhältliche), Tridecylsalicylat (welches unter der Handelsbezeichnung Cosmacol ESI bei der Fa. Sasol erhältlich ist), C12-C15 Alkylsalicylat (unter der Handelsbezeichnung Dermol NS bei der Fa. Alzo erhältlich), Hexa- decylbenzoat und Butyloctylbenzoat und Gemische davon (Hallstar AB) und/oder Diethylhexyl- naphthalat (Hallbrite TQ oder Corapan TQ von Symrise).Advantageous oil components are also z. B. Butyloctylsalicylat (for example, that available under the trade name Hallbrite BHB at the company. CP Hall), tridecyl salicylate (which is available under the trade name Cosmacol ESI from Fa. Sasol), C12-C15 alkyl salicylate (under the trade name Dermol NS in the Fa Alzo available), hexadecyl benzoate and butyl octyl benzoate and mixtures thereof (Hallstar AB) and / or diethylhexyl naphthalate (Hallbrite TQ or Corapan TQ from Symrise).
Auch beliebige Abmischungen solcher Öl- und Wachskomponenten sind vorteilhaft im Sinne der vorliegenden Erfindung einzusetzen.Any mixtures of such oil and wax components are also advantageous to use in the context of the present invention.
Ferner kann die Ölphase ebenfalls vorteilhaft auch unpolare Öle enthalten, beispielsweise solche, welche gewählt werden aus der Gruppe der verzweigten und unverzweigten Kohlenwasserstoffe und -wachse, insbesondere Mineralöl, Vaseline (Petrolatum), Paraffinöl, Squalan und Squalen, Polyolefine, hydrogenierte Polyisobutene, C13-16 Isoparaffin, Isohexadecan, Dimethicon und Cyclomethicon. Unter den Polyolefinen sind Polydecene die bevorzugten Substanzen.Furthermore, the oil phase can also advantageously contain non-polar oils, for example those which are selected from the group of branched and unbranched hydrocarbons and waxes, in particular mineral oil, Vaseline (petrolatum), paraffin oil, squalane and squalene, polyolefins, hydrogenated polyisobutenes, C13- 16 isoparaffin, isohexadecane, dimethicone and cyclomethicone. Among the polyolefins, polydecenes are the preferred substances.
Die erfindungsgemäßen Zubereitungen können ferner vorteilhaft eine oder mehrere Substanzen aus der folgenden Gruppe der Siloxanelastomere enthalten,:The preparations according to the invention can furthermore advantageously contain one or more substances from the following group of siloxane elastomers:
(a)Siloxanelastomere, welche die Einheiten R2SiO und RSiO1 5 und/oder R3SiO0,5 und/oder SiO2 enthalten, wobei die einzelnen Reste R jeweils unabhängig voneinander Wasserstoff, C1-24-Alkyl (wie beispielsweise Methyl, Ethyl, Propyl) oder Aryl (wie beispielsweise Phenyl oder ToIyI), Alkenyl (wie beispielsweise Vinyl) bedeuten und das Gewichtsverhältnis der Einheiten R2SiO zu RSIOL5 aus dem Bereich von 1 : 1 bis 30 : 1 gewählt wird; (b)Siloxanelastomere, welche in Silikonöl unlöslich und quellfähig sind, die durch die(A) siloxane elastomers containing the units R 2 SiO and RSiO 1 5 and / or R 3 SiO 0 , 5 and / or SiO 2 , wherein the individual radicals R are each independently hydrogen, C 1-24 alkyl (such as Methyl, ethyl, propyl) or aryl (such as phenyl or ToIyI), alkenyl (such as vinyl) and the weight ratio of the units R 2 SiO to RSIOL 5 is selected from the range of 1: 1 to 30: 1; (b) siloxane elastomers which are insoluble and swellable in silicone oil, which are characterized by
Additionsreaktion eines Organopolysiloxans (1 ), das siliciumbebundenen Wasserstoff enthält, mit einem Organopolysiloxan (2), das ungesättigte aliphatische Gruppen enthält, erhältlich sind, wobei die verwendeten Mengenateile so gewählt werden, dass die Menge des Wasserstoffes des Organopolysiloxans (1 ) oder der ungesättigten aliphatischen Gruppen des Organopolysiloxans (2)Addition reaction of an organopolysiloxane (1) containing silicon-bonded hydrogen, with an organopolysiloxane (2) containing unsaturated aliphatic groups are available, wherein the amounts used are such that the amount of hydrogen of the organopolysiloxane (1) or the unsaturated aliphatic Groups of Organopolysiloxane (2)
• im Bereich von 1 bis 20 mol-% liegt, wenn das Organopolysiloxan nicht zyklisch ist und In the range of 1 to 20 mol%, if the organopolysiloxane is not cyclic and
• im Bereich von 1 bis 50 mol-% liegt, wenn das Organopolysiloxan zyklisch ist. Vorteilhaft im Sinne der vorliegenden Erfindung liegen das oder die Siloxanelastomere in Form sphärischer Puder oder in Form von Gelen vor. In the range of 1 to 50 mol%, when the organopolysiloxane is cyclic. Advantageously in the context of the present invention, the siloxane elastomer (s) are in the form of spherical powders or in the form of gels.
Erfindungsgemäß vorteilhafte in Form sphärischer Puder vorliegende Siloxanelastomere sind die mit der INCI-Bezeichnung Dimethicone / Vinyl Dimethicone Crosspolymer, beispielsweise das von DOW CORNING unter der Handelsbezeichnungen DOW CORNING 9506 Powder erhältliche.Advantageously present in the form of spherical powders siloxane elastomers are those with the INCI name dimethicone / vinyl dimethicone crosspolymer, for example that available from DOW CORNING under the trade names DOW CORNING 9506 Powder available.
Besonders bevorzugt ist es, wenn das Siloxanelastomer in Kombination mit Ölen aus Kohlenwasserstoffen tierischer und/oder pflanzlicher Herkunft, synthetischen Ölen, synthetischen Estern, synthetischen Ethern oder deren Gemischen verwendet wird.It is particularly preferred if the siloxane elastomer is used in combination with oils of hydrocarbons of animal and / or vegetable origin, synthetic oils, synthetic esters, synthetic ethers or mixtures thereof.
Besonders vorteilhafte Zubereitungen werden ferner erhalten, wenn als Zusatz- oder Wirkstoffe Antioxidantien eingesetzt werden. Erfindungsgemäß enthalten die Zubereitungen vorteilhaft eines oder mehrere Antioxidantien. Als günstige, aber dennoch fakultativ zu verwendende Antioxidantien können alle für kosmetische Anwendungen geeigneten oder gebräuchlichen Antioxidantien verwendet werden.Particularly advantageous preparations are also obtained when antioxidants are used as additives or active ingredients. According to the invention, the preparations advantageously contain one or more antioxidants. As favorable, but nevertheless optional to be used antioxidants all suitable or common for cosmetic applications antioxidants can be used.
Besonders vorteilhaft im Sinne der vorliegenden Erfindung können wasserlösliche Antioxidan- tien eingesetzt werden, wie beispielsweise Vitamine, z. B. Ascorbinsäure und deren Derivate.Particularly advantageous for the purposes of the present invention, water-soluble antioxidants can be used, such as vitamins, eg. As ascorbic acid and its derivatives.
Bevorzugte Antioxidantien sind ferner Vitamin E und dessen Derivate sowie Vitamin A und dessen Derivate.Further preferred antioxidants are vitamin E and its derivatives as well as vitamin A and its derivatives.
Die Menge der Antioxidantien (eine oder mehrere Verbindungen) in den Zubereitungen beträgt vorzugsweise 0,001 bis 30 Gew.-%, besonders bevorzugt 0,05 bis 20 Gew.-%, insbesondere 0,1 bis 10 Gew.-%, bezogen auf das Gesamtgewicht der Zubereitung.The amount of the antioxidants (one or more compounds) in the preparations is preferably 0.001 to 30 wt .-%, particularly preferably 0.05 to 20 wt .-%, in particular 0.1 to 10 wt .-%, based on the total weight the preparation.
Sofern Vitamin E und/oder dessen Derivate das oder die Antioxidantien darstellen, ist vor- teilhaft, deren jeweilige Konzentrationen aus dem Bereich von 0,001 bis 10 Gew.-%, bezogen auf das Gesamtgewicht der Formulierung, zu wählen.If vitamin E and / or its derivatives are the antioxidant (s), it is advantageous to choose their respective concentrations from the range from 0.001 to 10% by weight, based on the total weight of the formulation.
Sofern Vitamin A bzw. Vitamin-A-Derivate, bzw. Carotine bzw. deren Derivate das oder die Antioxidantien darstellen, ist vorteilhaft, deren jeweilige Konzentrationen aus dem Bereich von 0,001 bis 10 Gew.-%, bezogen auf das Gesamtgewicht der Formulierung, zu wählen. Es ist insbesondere vorteilhaft, wenn die kosmetischen Zubereitungen gemäß der vorliegenden Erfindung kosmetische Wirkstoffe enthalten, wobei bevorzugte Wirkstoffe Antioxidantien sind, •welche die Haut vor oxidativer Beanspruchung schützen können.If vitamin A or vitamin A derivatives, or carotenes or derivatives thereof, are the antioxidant (s), it is advantageous if their respective concentrations are in the range from 0.001 to 10% by weight, based on the total weight of the formulation choose. It is particularly advantageous if the cosmetic preparations according to the present invention contain cosmetic active ingredients, preferred active substances being antioxidants which can protect the skin against oxidative stress.
Erfindungsgemäße Rezepturen, welche z. B. bekannte Antifaltenwirkstoffe wie Flavonglycoside (insbesondere α-Glycosylrutin), Coenzym Q10, Vitamin E und/oder Derivate und dergleichen enthalten, eignen sich insbesondere vorteilhaft zum Schutz vor ästhetisch unattraktiven Hautveränderungen, wie sie z. B. bei der Hautalterung auftreten (wie beispielsweise Trockenheit, Rauhigkeit und Ausbildung von Trockenheitsfältchen, Juckreiz, verminderte Rückfettung (z. B. nach dem Waschen), sichtbare Gefäßerweiterungen (Teleangiektasien, Cuperosis), Schlaffheit und Ausbildung von Falten und Fältchen, lokale Hyper-, Hypo- und Fehlpigmentierungen (z. B. Altersflecken), vergrößerte Anfälligkeit gegenüber mechanischem Stress (z. B. Rissigkeit) und dergleichen) und ermüdete Haut. Weiterhin vorteilhaft eignen sie sich gegen das Erscheinungsbild der trockenen bzw. rauhen Haut.Inventive formulations which z. B. known anti-wrinkle active ingredients such as flavone glycosides (especially α-glycosyl rutin), coenzyme Q10, vitamin E and / or derivatives and the like, are particularly advantageous for protection against aesthetically unattractive skin lesions, as described for. Skin aging (such as dryness, roughness, dryness wrinkles, itching, decreased refatting (eg, after washing), visible vascular dilation (telangiectasia, cuperosis), slackness and wrinkle and wrinkle formation, localized hypersensitivity). , Hypo and false pigmentation (eg, age spots), increased susceptibility to mechanical stress (eg, cracking), and the like) and tired skin. Furthermore, they are advantageously suitable against the appearance of dry or rough skin.
Die kosmetischen Zubereitungen gemäß der Erfindung können kosmetische Hilfsstoffe enthalten, wie sie üblicherweise in solchen Zubereitungen verwendet werden, z. B. Konservierungsmittel, Konservierungshelfer, Komplexbildner, Bakterizide, Parfüme, Substanzen zum Verhindern oder Steigern des Schäumens, Farbstoffe, Pigmente, die eine färbende Wirkung haben, Verdickungsmittel, anfeuchtende und/oder feuchhaltende Substanzen,The cosmetic preparations according to the invention may contain cosmetic adjuvants, such as are commonly used in such preparations, for. Preservatives, preservatives, complexing agents, bactericides, perfumes, substances for preventing or increasing foaming, dyes, pigments having a coloring effect, thickeners, moisturizing and / or moisturizing substances,
Füllstoffe, die das Hautgefühl verbessern, Fette, Öle, Wachse oder andere übliche Bestandteile einer kosmetischen oder dermatologischen Formulierung wie Alkohole, Polyole, Polymere, Schaumstabilisatoren, Elektrolyte, organische Lösungsmittel oder Silikonderivate.Fillers that improve the feel on the skin, fats, oils, waxes or other common ingredients of a cosmetic or dermatological formulation such as alcohols, polyols, polymers, foam stabilizers, electrolytes, organic solvents or silicone derivatives.
Es ist erfindungsgemäß vorteilhaft, wenn die erfindungsgemäße Zubereitung in Form einer Emulsion oder Hydrodispersion vorliegt.It is advantageous according to the invention if the preparation according to the invention is in the form of an emulsion or hydrodispersion.
Es ist erfindungsgemäß bevorzugt, wenn die erfindungsgemäße Zubereitung in Form einer Emulsion vorliegt.It is preferred according to the invention if the preparation according to the invention is in the form of an emulsion.
In einer erfindungsgemäß bevorzugten Ausführungsform der vorliegenden Erfindung liegt die Zubereitung in Form einer O/W-Emulsion vor.In a preferred embodiment of the present invention, the preparation is in the form of an O / W emulsion.
In diesem Falle ist es erfindungsgemäß bevorzugt, wenn die Zubereitung einen oder mehrere O/W-Emulgatoren gewählt aus der Gruppe der Verbindungen Glycerylstearatcitrat, Glycerylstearat (selbstemulgierend), Stearinsäure, Stearatsalze, Polyglyceryl-3- methylglycosedistearat, Ceteareth-20, PEG-40 Stearat, Natriumcetearylsulfat, Kaliumcetylphosphat, Natriumstearoylglutamat, Sucrosepolystearat, Hydrogenated Polyisobutene enthält.In this case, it is preferred according to the invention if the preparation comprises one or more O / W emulsifiers selected from the group of the compounds glyceryl stearate citrate, glyceryl stearate (self-emulsifying), stearic acid, stearate salts, polyglyceryl-3-methylglycose distearate, ceteareth-20, PEG-40 stearate , Sodium cetearyl sulfate, Potassium cetyl phosphate, sodium stearoyl glutamate, sucrose polystearate, hydrogenated polyisobutenes.
Diese erfindungsgemäßen O/W-Emulgatoren können erfindungsgemäß vorteilhaft in einer Konzentration von 0,001 bis 10 Gewichts-% und bevorzugt in einer Konzentration von 0,1 bis 7 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung in dieser enthalten sein.According to the invention, these O / W emulsifiers according to the invention may advantageously be present in a concentration of from 0.001 to 10% by weight and preferably in a concentration of from 0.1 to 7% by weight, based on the total weight of the preparation.
Eine andere erfindungsgemäß bevorzugte Ausführüngsform der vorliegenden Erfindung ist dadurch gekennzeichnet, dass die Zubereitung in Form einer W/O-Emulsion vorliegt.Another embodiment of the present invention which is preferred according to the invention is characterized in that the preparation is in the form of a W / O emulsion.
Bei dieser Ausführungsform ist es erfindungsgemäß bevorzugt, wenn die Zubereitung einen oder mehrere W/O-Emulgatoren gewählt aus der Gruppe der Verbindungen Polyglyceryl-2- dipolyhydroxystearat, PEG-30 Dipolyhydroxystearat, Cetyl Dimethicon Copolyol, Polyglyceryl-3 Diisostearat enthält.In this embodiment, it is preferred according to the invention if the preparation contains one or more W / O emulsifiers selected from the group of the compounds polyglyceryl-2-dipolyhydroxystearate, PEG-30 dipolyhydroxystearate, cetyl dimethicone copolyol, polyglyceryl-3 diisostearate.
Diese erfindungsgemäßen W/O-Emulgatoren können erfindungsgemäß vorteilhaft in einer Konzentration von 0,1 bis 10 Gewichts-% und bevorzugt in einer Konzentration von 0,2 bis 7 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung in dieser enthalten sein. According to the invention, these W / O emulsifiers according to the invention may advantageously be present in a concentration of from 0.1 to 10% by weight and preferably in a concentration of from 0.2 to 7% by weight, based on the total weight of the preparation.
Vergleichsversuch: Erhöhung der Wasserfestigkeit von SonnenschutzproduktenComparative experiment: Increasing the water resistance of sunscreen products
Vergleichsversuche Styrene-Acrylate Copolvmer gegen VP/Hexadecene Copolymer und filmbildnerfreie FormulierungComparative Experiments Styrene-Acrylate Copolvent vs. VP / Hexadecene Copolymer and Film Forming-Free Formulation
In Vergleichsversuchen zur Fähigkeit verschiedener Polymere, die Wasserfestigkeit von Sonnenschutzprodukten zu erhöhen, wurden die einzelnen Polymere in der gleichen Konzentration in das Testsystem eingearbeitet und dessen Wasserfestigkeit in-vitro bestimmt.In comparative experiments on the ability of various polymers to increase the water resistance of sunscreen products, the individual polymers were incorporated in the same concentration in the test system and its water resistance determined in vitro.
Als Testrezeptur diente:The test recipe was:
Rohstoff (INCI) Anteil (Gew.%)Commodity (INCI) share (% by weight)
Glyceryl Stearate SE 1 ,0Glyceryl Stearate SE 1, 0
Cetearyl Alcohol+ PEG-40 Castor OiI+ Sodium Cetearyl Sulfate 2,5Cetearyl Alcohol + PEG-40 Castor OiI + Sodium Cetearyl Sulfate 2.5
Cetyl Alcohol 1 ,5Cetyl Alcohol 1, 5
Bis-Ethylhexyloxyphenole Methoxyphenyl Triazine 3,0Bis-Ethylhexyloxyphenols Methoxyphenyl Triazines 3.0
Butyl Methoxydibenzoylmethane 4,5Butyl methoxydibenzoylmethane 4,5
C12-15 Alkyl Benzoate 11 ,0C12-15 alkyl benzoates 11, 0
Propylparaben 0,1Propylparaben 0.1
Phenoxyethanol 0,6Phenoxyethanol 0.6
Ethylhexyl Methoxycinnamate 9,5Ethylhexyl methoxycinnamate 9.5
Xanthan Gum 0,4Xanthan Gum 0.4
Glycerin 1 ,0Glycerol 1, 0
Trisodium EDTA 1 ,0Trisodium EDTA 1, 0
Aqua 52,0Aqua 52.0
Aqua+ Sodium Hydroxide 1 ,1Aqua + Sodium Hydroxide 1, 1
Phenylbenzimidazole Sulfonic Acid 2,0Phenylbenzimidazole sulfonic acid 2.0
Ethylparaben 0,1Ethylparaben 0.1
Methylparaben 0,3Methylparaben 0.3
Alcohol denat. 8,0Alcohol denate. 8.0
Parfüm 0,4Perfume 0.4
Entsprechend der Lipophilie wurde VP/Hexadecene Copolymer in die Fettphase und die Styrene/Acrylate Copolymer Dispersion in die Wasserphase eingearbeitet. Die eingesetzte Polymerkonzentration betrug in beiden Fällen 10% aktives Polymer. (VP/Hexadecene Copolymer lag als Reinsubstanz, Styrene/Acrylate Copolymer als Dispersion mit 46% Feststoffanteil vor.)According to the lipophilicity VP / hexadecene copolymer was incorporated into the fatty phase and the styrene / acrylate copolymer dispersion in the water phase. The polymer concentration used was 10% active polymer in both cases. (VP / hexadecenes copolymer was present as pure substance, styrene / acrylate copolymer as dispersion with 46% solids content.)
Der in-vitro Wasserfestigkeitstest wurde wie folgt durchgeführt:The in vitro water resistance test was carried out as follows:
Als Substrat für den Test dient ein künstliches Hautmodell namens Vitro Skin, das von der IMS Testing Group vertrieben wird. Es soll sich um eine Matrix handeln, die sowohl Proteine als auch Lipide enthält und hinsichtlich ihrer Topographie, pH-Wert und Oberflächenspannung der menschlichen Haut ähnelt.The substrate for the test is an artificial skin model called Vitro Skin, which is distributed by the IMS Testing Group. It should be a matrix that contains both proteins and lipids and resembles the topography, pH and surface tension of human skin.
Das Substrat wird in kleine Stücke von 2,8cm x 3,8cm Größe geschnitten und anschließend der Herstelleranweisung entsprechend über 16-18 Stunden bei einer genau eingestellten Luftfeuchtigkeit in einer Feuchtigkeitskammer gelagert. Die so vorbereiteten Substratstücke werden mit 20mg Formulierung gleichmäßig eingecremt und die Stücke in handelsübliche Diarahmen eingespannt.The substrate is cut into small pieces of 2.8 cm x 3.8 cm in size and then stored according to the manufacturer's instructions for 16-18 hours at a precisely set humidity in a humidity chamber. The prepared substrate pieces are evenly creamed with 20 mg formulation and the pieces are clamped in commercially available slide frames.
Nach 20 Minuten, in denen die Formulierung koalesziert (in der Feuchtigkeitskammer), werden an 5 verschiedenen Stellen auf einem VitroSkin Stück Absorptionsspektren im Wellenlängenbereich von 280-420nm aufgenommen und aus ihnen ein Mittelwertspektrum errechnet. Als Referenz dient dabei hydrierte aber ansonsten unbehandelte VitroSkin. Es schließt sich ein 80 minütiges Bad in einem 2L Becherglas mit leichter Wasserbewegung (Blattrührer mit 50 rpm) an. Die Proben werden eine halbe Stunde lang bei normaler Raumfeuchtigkeit und anschließend für 2 Stunden in der Feuchtigkeitskammer gelagert, bevor erneut Absorptionsspektren aufgenommen werden (gleiche Orte und gleicher Wellenlängenbereich wie die ersten Spektren).After 20 minutes in which the formulation coalesces (in the humidity chamber), absorbance spectra in the wavelength range of 280-420nm are recorded at 5 different sites on a VitroSkin piece and an average range is calculated from them. Hydrogenated but otherwise untreated VitroSkin serves as a reference. This is followed by an 80-minute bath in a 2L beaker with gentle water movement (paddle stirrer at 50 rpm). Samples are stored for half an hour at normal room humidity and then for 2 hours in the humidity chamber before resuming absorption spectra (same locations and same wavelength range as the first spectra).
Zur Auswertung werden die Integrale der jeweiligen Mittelwertspektren einer Probe vor und nach dem Badevorgang, so dass sich die in-vitro Wasserfestigkeit wie folgt ergibt:For evaluation, the integrals of the respective mean value spectra of a sample before and after the bathing process, so that the in vitro water resistance results as follows:
A20nm \Spektrum gεwaschen Gεwaschen A20nm \ spectrum
*F = Ä *100% jSpekti rum eingecremt itOnm* F = Ä * 100% jSpekti rum creamed itOnm
In diesem Modell erreicht die filmbildnerfreie Testformulierung eine in-vitro Wasserfestigkeit von 38,05%. Der zur Zeit in vielen Sonnenschutzrezepturen standardmäßig eingesetzte Filmbildner VP/Hexadecene Copolymer erzielte bei einer Einsatzkonzentration von 10% einen ■Wasserfestigkeitswert von 48,69%, während mit dem Styrene/Acrylate Copolymer „Joncryl 1532" 53,61% und dem Styrene/Acrylate Copolymer „Joncryl ECO2124" 83,13% erzielt werden konnten.In this model, the film former-free test formulation achieves an in vitro water resistance of 38.05%. The film former VP / Hexadecene Copolymer currently used as standard in many sunscreen formulations achieved a waterfastness value of 48.69% at a use concentration of 10%, while with the styrene / acrylate copolymer "Joncryl 1532" it was 53.61% and the styrene / acrylate copolymer "Joncryl ECO2124" 83.13% could be achieved.
Figure imgf000017_0001
Figure imgf000017_0001
BeispieleExamples
Die nachfolgenden Beispiele sollen die vorliegende Erfindung verdeutlichen, ohne sie einzuschränken. Alle Mengenangaben, Anteile und Prozentanteile sind, soweit nicht anders angegeben, auf das Gewicht und die Gesamtmenge bzw. auf das Gesamtgewicht der Zubereitungen bezogen.The following examples are intended to illustrate the present invention without limiting it. Unless indicated otherwise, all amounts, proportions and percentages are based on the weight and the total amount or on the total weight of the preparations.
Figure imgf000018_0001
Figure imgf000019_0001
Figure imgf000018_0001
Figure imgf000019_0001
Figure imgf000020_0001
Figure imgf000021_0001
Figure imgf000020_0001
Figure imgf000021_0001
Figure imgf000022_0001
Figure imgf000023_0001
Figure imgf000022_0001
Figure imgf000023_0001

Claims

Patentansprüche claims
1. Kosmetische Zubereitung enthaltend a) Styrol/Acrylat-Copolymere und b) ein oder mehrere UV-Lichtschutzfilter. 1. Cosmetic preparation containing a) styrene / acrylate copolymers and b) one or more UV light protection filters.
2. Verwendung von Styrol/Acrylat-Copolymeren zur Erhöhung der Wasserfestigkeit von kosmetischen Sonnenschutzmitteln.2. Use of styrene / acrylate copolymers to increase the water resistance of cosmetic sunscreens.
3. Verwendung von Styrol/Acrylat-Copolymeren zur Erhöhung der Schweißfestigkeit von kosmetischen Sonnenschutzmitteln.3. Use of styrene / acrylate copolymers to increase the sweat resistance of cosmetic sunscreens.
4. Kosmetische Zubereitung nach Anspruch 1 oder Verwendung nach Anspruch 2 oder 3, dadurch gekennzeichnet, dass die Styrol/Acrylat-Copolymere eine4. Cosmetic preparation according to claim 1 or use according to claim 2 or 3, characterized in that the styrene / acrylate copolymers a
Glasübergangstemperatur von kleiner oder gleich 20 0C aufweisen.Glass transition temperature of less than or equal to 20 0 C have.
5. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Zubereitung Styrol/Acrylat-Copolymer in einer Konzentration von 0,1 bis 15 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält.5. Cosmetic preparation or use according to one of the preceding claims, characterized in that the preparation contains styrene / acrylate copolymer in a concentration of 0.1 to 15% by weight, based on the total weight of the preparation.
6. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Zubereitung UV-Lichtschutzfilter in einer Gesamtmenge von 0,2 bis 30 Gewichts-%, bezogen auf das Gesamtgewicht der Zubereitung, enthält. 6. Cosmetic preparation or use according to one of the preceding claims, characterized in that the preparation contains UV light protection filters in a total amount of 0.2 to 30% by weight, based on the total weight of the preparation.
7. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden7. Cosmetic preparation or use according to one of the preceding
Ansprüche, dadurch gekennzeichnet, dass die UV-Lichtschutzfilter gewählt werden aus der Gruppe der Verbindungen Phenylen-1 ,4-bis-(2-benzimidazyl)-3,3'-5,5'- tetrasulfonsäuresalze; 2-Phenylbenzimidazol-5-sulfonsäuresalze; 1 ,4-di(2-oxo-10-Sulfo- 3-bornylidenmethyl)-Benzol und dessen Salze; 4-(2-Oxo-3-bornylidenmethyl)ben- zolsulfonsäuresalze; 2-Methyl-5-(2-oxo-3-bomylidenmethyl)sulfonsäuresalze; 2,2'-Me- thylen-bis-(6-(2H-benzotriazol-2-yl)-4-(1 ,1 ,3,3-tetramethylbuty!)-phenol); 2-(2H-benzo- triazol-2-yl)-4-methyl-6-[2-methyl-3-[1 ,3,3,3-tetramethyl-1-[(trimethylsilyl)oxy]disiloxa- nyl]propyl]-phenol; 3-(4-Methylbenzyliden)campher; 3-Benzylidencampher; Ethylhexylsalicylat; Terephthalidendicamphersulfonsäure; 4-(Dimethylamino)- benzoesäure(2-ethylhexyl)ester; 4-(Dimethylamino)benzoesäure-amylester; 4-Claims, characterized in that the UV photoprotective filters are selected from the group of compounds phenylene-1,4-bis (2-benzimidazyl) -3,3'-5,5'-tetrasulfonsäuresalze; 2-phenylbenzimidazole-5-sulfonic acid salts; 1,4-di (2-oxo-10-sulfo-3-bomylidenemethyl) benzene and its salts; 4- (2-oxo-3-bomylidenemethyl) benzene sulfonic acid salts; 2-methyl-5- (2-oxo-3-bornylidenemethyl) sulfonic acid salts; 2,2'-methyl-bis (6- (2H-benzotriazol-2-yl) -4- (1,1,3,3-tetramethylbutyl) -phenol); 2- (2H-benzotriazol-2-yl) -4-methyl-6- [2-methyl-3- [1,3,3,3-tetramethyl-1 - [(trimethylsilyl) oxy] disiloxanyl] propyl] -phenol; 3- (4-methylbenzylidene) camphor; 3-benzylidenecamphor; ethylhexyl salicylate; Terephthalidendicamphersulfonsäure; 2-ethylhexyl 4- (dimethylamino) benzoate; 4- (dimethylamino) benzoic acid amyl ester; 4
Methoxybenzalmalon-säuredi(2-ethylhexyl)ester; 4-Methoxyzimtsäure(2- ethylhexyl)ester; 4-Methoxyzimtsäureisoamylester; 2-Hydroxy-4-methoxybenzophenon, 2-Hydroxy-4-methoxy-4'-methylbenzophenon; 2,2'-Dihydroxy-4-methoxybenzophenon; 2-(4'-Diethylamino-2'-hydoxybenzoyl)-benzoesäurehexylester, 4-(tert.-Butyl)-4'-methoxy- dibenzoylmethan; Homomenthylsalicylat; 2-Ethylhexyl-2-hydroxybenzoat; 2-Ethylhexyl-Methoxybenzalmalon-säuredi (2-ethylhexyl) ester; 2-ethylhexyl 4-methoxycinnamate; Isoamyl 4-methoxycinnamate; 2-hydroxy-4-methoxybenzophenone, 2-hydroxy-4-methoxy-4'-methylbenzophenone; 2,2'-dihydroxy-4-methoxybenzophenone; Hexyl 2- (4'-diethylamino-2'-hydroxybenzoyl) benzoate, 4- (tert-butyl) -4'-methoxydibenzoylmethane; homomenthyl; 2-ethylhexyl 2-hydroxybenzoate; 2-ethylhexyl
2-cyano-3,3-diphenylacrylat; Dimethicodiethylbenzalmalonat; 3-(4-(2,2-bis Ethoxycarbonylvinyl)-phenoxy)propenyl)-methoxysiloxan / Dimethylsiloxan - Copolymer; 2,4-Bis-{[4-(2-ethyl-hexyloxy)-2-hydroxy]-phenyl}-6-(4-methoxyphenyl)-1 ,3,5-triazin (INCI Bis-Ethylhexyloxyphenol Methoxyphenyl Triazin); Dioctylbutylamidotriazon (INCI: Diethylhexyl-Butamidotriazone); 2,4-bis-[5-1(dimethylpropyl)benzoxazol-2-yl-(4-phenyl)- imino]-6-(2-ethylhexyl)-imino-1 l3,5-triazin mit der (CAS Nr. 288254-16-0); 4,4',4"-(1 ,3,5- Triazin-2I4,6-triyltriimino)-tris-benzoesäure-tris(2-ethylhexylester) (auch: 2,4,6-Tris- [anilino-(p-carbo-2'-ethyl-1 '-hexyloxy)]-1 ,3,5-triazin (INCI: Ethylhexyl Triazone); 2,4,6-2-cyano-3,3-diphenylacrylate; dimethicodiethylbenzalmalonate; 3- (4- (2,2-bisethoxycarbonylvinyl) phenoxy) propenyl) methoxysiloxane / dimethylsiloxane copolymer; 2,4-Bis - {[4- (2-ethyl-hexyloxy) -2-hydroxy] -phenyl} -6- (4-methoxyphenyl) -1, 3,5-triazine (INCI Bis-ethylhexyloxyphenol methoxyphenyl triazine); Dioctylbutylamidotriazone (INCI: diethylhexyl-butamidotriazone); 2,4-bis- [5-1 (dimethylpropyl) benzoxazol-2-yl- (4-phenyl) -imino] -6- (2-ethylhexyl) -imino-1 l- 3,5-triazine having the (CAS Nos 288254-16-0); 4,4 ', 4 "- (1, 3,5-triazine-2 I 4,6-triyltriimino) (-tris-benzoic acid tris (2-ethylhexyl) also: 2,4,6-tris- [anilino- (p-carbo-2'-ethyl-1'-hexyloxy)] - 1, 3,5-triazine (INCI: ethylhexyl triazone); 2,4,6-
Tribiphenyl-4-yl-1 ,3,5-triazin; Hydroxyphenylbenzophenon; Merocyanine; Titiandioxid; Zinkoxid.Tribiphenyl-4-yl-1,3,5-triazine; Hydroxyphenylbenzophenon; merocyanines; Titiandioxid; Zinc oxide.
8. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Zubereitung eine Viskosität von 100 bis 20 000 mPaS aufweist.8. Cosmetic preparation or use according to one of the preceding claims, characterized in that the preparation has a viscosity of 100 to 20,000 mPaS.
9. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Zubereitung in Form einer Emulsion vorliegt.9. Cosmetic preparation or use according to one of the preceding claims, characterized in that the preparation is in the form of an emulsion.
10. Kosmetische Zubereitung oder Verwendung nach einem der vorhergehenden Ansprüche, dadurch gekennzeichnet, dass die Zubereitung einen oder mehrere10. Cosmetic preparation or use according to one of the preceding claims, characterized in that the preparation one or more
Wirkstoffe gewählt aus der Gruppe der Verbindungen Vitamin A und dessen Derivate, Vitamin C und dessen Derivate, Niacinamid, Panthenol, alpha-Liponsäure, Folsäure, Phytoen, D-Biotin, Coenzym Q10, alpha-Glucosylrutin, Carnitin, Carnosin, natürliche und/oder synthetische Isoflavonoide, Flavonoide, Kreatin, Kreatinin, Taurin, ß-Alanin und/oder Licochalcon A enthält. Active ingredients selected from the group of compounds vitamin A and its derivatives, vitamin C and its derivatives, niacinamide, panthenol, alpha-lipoic acid, folic acid, phytoene, D-biotin, coenzyme Q10, alpha-glucosylrutin, carnitine, carnosine, natural and / or synthetic isoflavonoids, flavonoids, creatine, creatinine, taurine, ß-alanine and / or licochalcone A contains.
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