WO2008140574A3 - Radiation protection and treatment for exposure to gamma-radiation - Google Patents

Radiation protection and treatment for exposure to gamma-radiation Download PDF

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Publication number
WO2008140574A3
WO2008140574A3 PCT/US2007/084875 US2007084875W WO2008140574A3 WO 2008140574 A3 WO2008140574 A3 WO 2008140574A3 US 2007084875 W US2007084875 W US 2007084875W WO 2008140574 A3 WO2008140574 A3 WO 2008140574A3
Authority
WO
WIPO (PCT)
Prior art keywords
radiation
exposure
gamma
treatment
protection
Prior art date
Application number
PCT/US2007/084875
Other languages
French (fr)
Other versions
WO2008140574A2 (en
Inventor
Wenlin Deng
Veeresa Gududuru
Gangadhar Durgam
Gabor Tigyi
Duane Miller
Original Assignee
Univ Tennessee Res Foundation
Wenlin Deng
Veeresa Gududuru
Gangadhar Durgam
Gabor Tigyi
Duane Miller
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Tennessee Res Foundation, Wenlin Deng, Veeresa Gududuru, Gangadhar Durgam, Gabor Tigyi, Duane Miller filed Critical Univ Tennessee Res Foundation
Priority to JP2009537375A priority Critical patent/JP2010510238A/en
Priority to CA2705612A priority patent/CA2705612A1/en
Priority to AU2007353320A priority patent/AU2007353320B2/en
Priority to EP07874288A priority patent/EP2099469A4/en
Publication of WO2008140574A2 publication Critical patent/WO2008140574A2/en
Publication of WO2008140574A3 publication Critical patent/WO2008140574A3/en
Priority to IL198789A priority patent/IL198789A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/661—Phosphorus acids or esters thereof not having P—C bonds, e.g. fosfosal, dichlorvos, malathion or mevinphos
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measurement Of Radiation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Disclosed are radioprotective agents and methods of use for decreasing cellular damage and cell death resulting from radiation exposure.
PCT/US2007/084875 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation WO2008140574A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
JP2009537375A JP2010510238A (en) 2006-11-15 2007-11-15 Methods of radiation protection and treatment against gamma radiation exposure
CA2705612A CA2705612A1 (en) 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation
AU2007353320A AU2007353320B2 (en) 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation
EP07874288A EP2099469A4 (en) 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation
IL198789A IL198789A0 (en) 2006-11-15 2009-05-17 Radiation protection and treatment for exposure to gamma-radiation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86587106P 2006-11-15 2006-11-15
US60/865,871 2006-11-15

Publications (2)

Publication Number Publication Date
WO2008140574A2 WO2008140574A2 (en) 2008-11-20
WO2008140574A3 true WO2008140574A3 (en) 2009-01-15

Family

ID=40002804

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084875 WO2008140574A2 (en) 2006-11-15 2007-11-15 Radiation protection and treatment for exposure to gamma-radiation

Country Status (6)

Country Link
EP (1) EP2099469A4 (en)
JP (1) JP2010510238A (en)
AU (1) AU2007353320B2 (en)
CA (1) CA2705612A1 (en)
IL (1) IL198789A0 (en)
WO (1) WO2008140574A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2015102856A1 (en) * 2013-12-30 2015-07-09 Rxbio Inc. Crystalline salts of (z)-o-octadec-9-en-1-yl o,o-dihydrogen phosphorothioate
US20170007559A1 (en) * 2015-07-12 2017-01-12 The University Of Tennessee Research Foundation Compositions and methods for protecting colonic epithelial barrier function
JPWO2018016523A1 (en) * 2016-07-20 2019-05-09 国立大学法人 長崎大学 New radiation protective agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060009507A1 (en) * 2003-10-09 2006-01-12 Miller Duane D LPA receptor agonists and antagonists and methods of use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1906972B1 (en) * 2005-07-19 2013-09-11 The University of Tennessee Research Foundation LPA2 receptor agonist for treating diarrhea

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060009507A1 (en) * 2003-10-09 2006-01-12 Miller Duane D LPA receptor agonists and antagonists and methods of use

Also Published As

Publication number Publication date
WO2008140574A2 (en) 2008-11-20
EP2099469A2 (en) 2009-09-16
AU2007353320A1 (en) 2008-11-20
AU2007353320B2 (en) 2014-01-23
CA2705612A1 (en) 2008-11-20
JP2010510238A (en) 2010-04-02
EP2099469A4 (en) 2013-02-27
IL198789A0 (en) 2011-08-01

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