WO2008140374A1 - Flow distributing valve - Google Patents
Flow distributing valve Download PDFInfo
- Publication number
- WO2008140374A1 WO2008140374A1 PCT/SE2008/000288 SE2008000288W WO2008140374A1 WO 2008140374 A1 WO2008140374 A1 WO 2008140374A1 SE 2008000288 W SE2008000288 W SE 2008000288W WO 2008140374 A1 WO2008140374 A1 WO 2008140374A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- port
- rotor
- stator
- orifice
- valve
- Prior art date
Links
Classifications
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
- F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
- F16K11/00—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves
- F16K11/02—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit
- F16K11/06—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements
- F16K11/072—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members
- F16K11/074—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members with flat sealing faces
- F16K11/0743—Multiple-way valves, e.g. mixing valves; Pipe fittings incorporating such valves with all movable sealing faces moving as one unit comprising only sliding valves, i.e. sliding closure elements with pivoted closure members with flat sealing faces with both the supply and the discharge passages being on one side of the closure plates
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1095—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers
- G01N35/1097—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices for supplying the samples to flow-through analysers characterised by the valves
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/16—Injection
- G01N30/20—Injection using a sampling valve
- G01N2030/202—Injection using a sampling valve rotary valves
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/86493—Multi-way valve unit
- Y10T137/86558—Plural noncommunicating flow paths
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T137/00—Fluid handling
- Y10T137/8593—Systems
- Y10T137/86493—Multi-way valve unit
- Y10T137/86863—Rotary valve unit
Definitions
- Solenoid valves tend to have limitations when used in applications where the fluid pressure is relatively high (such as pressures above approximately 0.5 MPa).
- Rotary valves can be designed to withstand high pressures (such as pressures above 30 MPa). They can be made from a range of materials, such as stainless steel, high performance polymeric materials and ceramics.
- Figure 13 is a schematic view of the inner stator face shown in Figure 11, also showing the position of the groove ends.
- Figure 14 is a schematic view of an inner rotor face of a rotor according to one embodiment of the invention. Said rotor is adapted to cooperate with a stator as shown in the Figures 8-13.
- Figure 19 is a schematic front view of the rotor position of the valve shown in Figure 18.
- the main parts of a typical rotary valve are schematically shown in Fig. 7 (wherein no brackets or similar load carrying or fastening elements are shown).
- the rotary valve 10 has a stator 11, a rotor 12, a rotary shaft 13 that optionally may be provided with means (not shown) for recognizing its angular position and a driving unit 14 typically comprising a gear box and a motor (although a valve also may be operated manually).
- the rotor is rotatable with respect to the stator around a rotary axis RA of the valve.
- the injection valve 303 is in it's LOAD position, the first selection valve 304 is set to connect to another column 313 inline (another column than was connected during the first operating mode), and the second selection valve 306 is set to connect one of the loops in-line, e.g. loop 315 that holds a sample fraction collected.
- the buffer liquid used is now forced through the flow distributing valve 301 to the second selection valve 306 to bring with it the sample fraction contained in the selected loop 315.
- the flow returns to the flow distributing valve 301 and from there to the first selection valve 304.
- a fraction that in this way is returned to the flow distributing valve 301 is further directed to the injection valve 302 and may, by acting on this valve, be contained in the capillary loop 311 for further treatment in yet another purification step (performed according to the first mode of operation).
- liquid may be discharged from the system via the injection valve 302, the flow distributing valve 301 and the outlet 318.
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- General Engineering & Computer Science (AREA)
- Mechanical Engineering (AREA)
- Multiple-Way Valves (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Description
Claims
Priority Applications (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/597,826 US8225817B2 (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
CA 2683944 CA2683944A1 (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
AU2008251098A AU2008251098B2 (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
JP2010508334A JP5377477B2 (en) | 2007-05-15 | 2008-04-24 | Flow distribution valve |
CN200880016262XA CN101680861B (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
EP20080741862 EP2147301A1 (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0701221 | 2007-05-15 | ||
SE0701221-4 | 2007-05-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2008140374A1 true WO2008140374A1 (en) | 2008-11-20 |
Family
ID=40002446
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/SE2008/000288 WO2008140374A1 (en) | 2007-05-15 | 2008-04-24 | Flow distributing valve |
Country Status (7)
Country | Link |
---|---|
US (1) | US8225817B2 (en) |
EP (1) | EP2147301A1 (en) |
JP (1) | JP5377477B2 (en) |
CN (1) | CN101680861B (en) |
AU (1) | AU2008251098B2 (en) |
CA (1) | CA2683944A1 (en) |
WO (1) | WO2008140374A1 (en) |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013116285A1 (en) | 2012-02-01 | 2013-08-08 | Waters Technologies Corporation | Managing fluidic connections to microfluidic devices |
JP2013533464A (en) * | 2010-05-20 | 2013-08-22 | バイオ−ラッド ラボラトリーズ,インコーポレイティド | Rotating cylindrical switching valve |
WO2015094095A1 (en) * | 2013-12-19 | 2015-06-25 | Ge Healthcare Bio-Sciences Ab | Rotary valve |
WO2015094096A1 (en) * | 2013-12-19 | 2015-06-25 | Ge Healthcare Bio-Sciences Ab | Rotary valve |
EP2888595A4 (en) * | 2012-08-22 | 2016-04-13 | Ge Healthcare Bio Sciences Ab | Versatile rotary valve |
US10746708B2 (en) | 2015-03-30 | 2020-08-18 | Ge Healthcare Bio-Sciences Ab | Rotary valve and a chromatography system |
Families Citing this family (28)
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---|---|---|---|---|
WO2009041442A1 (en) * | 2007-09-28 | 2009-04-02 | Shimadzu Corporation | Sample introduction device |
EP2196801B1 (en) * | 2008-12-11 | 2017-08-23 | Spark Holland B.V. | Method and apparatus for injecting a liquid sample in an HPLC analyzing device, and valve assembly for use therein. |
WO2011001460A1 (en) * | 2009-06-29 | 2011-01-06 | 株式会社島津製作所 | Flow path switching valve |
JP5240245B2 (en) * | 2010-06-22 | 2013-07-17 | 東京エレクトロン株式会社 | Channel switching device, processing device, channel switching method and processing method, and storage medium |
DE102011000104B4 (en) * | 2011-01-12 | 2013-02-07 | Dionex Softron Gmbh | High pressure switching valve for high performance liquid chromatography |
US9939415B2 (en) | 2011-01-12 | 2018-04-10 | Dionex Softron Gmbh | High-pressure control valve for high-performance liquid chromatography |
US8701711B2 (en) | 2011-06-13 | 2014-04-22 | Daniel Sharron | Continuously adjustable, multi-port selection, constant flow capability, externally-actuated rotary flow valve apparatus, system and method |
US9304518B2 (en) | 2011-08-24 | 2016-04-05 | Bio-Rad Laboratories, Inc. | Modular automated chromatography system |
US8960231B2 (en) | 2011-09-21 | 2015-02-24 | Neil Robert Picha | Multi-mode injection valve |
US9200715B2 (en) * | 2011-11-11 | 2015-12-01 | Shimadzu Corporation | Passage-switching valve |
US9182886B2 (en) | 2011-11-14 | 2015-11-10 | Bio-Rad Laboratories Inc. | Chromatography configuration interface |
US8813785B2 (en) * | 2012-01-09 | 2014-08-26 | Promochrom Technologies Ltd. | Fluid selection valve |
CN102836492A (en) * | 2012-09-20 | 2012-12-26 | 深圳市瑞沃德生命科技有限公司 | Zero safety protection device of anesthesia machine evaporator |
CN103423483B (en) * | 2013-09-11 | 2015-08-26 | 青岛普仁仪器有限公司 | valve and chromatograph |
CN103423484B (en) * | 2013-09-11 | 2015-08-26 | 青岛普仁仪器有限公司 | valve and chromatograph |
EP3105580B1 (en) * | 2014-02-14 | 2023-10-04 | Cytiva Sweden AB | Automated multi-step purification system |
US9752691B1 (en) | 2014-07-03 | 2017-09-05 | Elemental Scientific, Inc. | Valve for controlled shuttle of liquid into microtiter plates and mixing |
CN104330508B (en) * | 2014-10-31 | 2016-10-05 | 华南理工大学 | Intelligence automatic switchover multichannel gas chromatographic column attachment means |
JP6651238B2 (en) * | 2014-12-15 | 2020-02-19 | ジーイー・ヘルスケア・バイオサイエンス・アクチボラグ | Rotary valves and systems |
CN104633182A (en) * | 2015-02-16 | 2015-05-20 | 苏州赛谱仪器有限公司 | Column-position valve |
GB201517282D0 (en) * | 2015-09-30 | 2015-11-11 | Ge Healthcare Bio Sciences Ab | A chromatography system and a method therefor |
EA201990485A1 (en) * | 2016-10-12 | 2019-10-31 | ROTARY VALVE DEVICE AND LIFT LIFTING DEVICE CONTAINING A ROTARY VALVE DEVICE | |
US10527192B2 (en) | 2018-02-15 | 2020-01-07 | Talis Biomedical Corporation | Rotary valve |
TWI640710B (en) * | 2018-04-13 | 2018-11-11 | 蘇釗登 | Rotary self-holding fluid flux solenoid valve |
CN109541094A (en) * | 2018-12-11 | 2019-03-29 | 苏州英赛斯智能科技有限公司 | A kind of selector valve and liquid-chromatography apparatus |
JP7472156B2 (en) * | 2019-02-20 | 2024-04-22 | エフ ホフマン-ラ ロッシュ アクチェン ゲゼルシャフト | Valve for transferring at least one fluid |
USD919833S1 (en) | 2019-03-06 | 2021-05-18 | Princeton Biochemicals, Inc | Micro valve for controlling path of fluids in miniaturized capillary connections |
US10820847B1 (en) | 2019-08-15 | 2020-11-03 | Talis Biomedical Corporation | Diagnostic system |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1263481A (en) * | 1968-04-02 | 1972-02-09 | Beckman Instruments Inc | Sample injector for use in liquid chromatography |
US4614204A (en) * | 1984-12-10 | 1986-09-30 | Uop Inc. | Rotary valve for interconnecting conduits in three groups |
US4625569A (en) * | 1984-01-17 | 1986-12-02 | Toyo Soda Manufacturing Co., Ltd. | Liquid injection device |
US6012488A (en) * | 1998-09-17 | 2000-01-11 | Rheodyne, L.P. | Segmenting valve |
US6672336B2 (en) * | 2001-11-28 | 2004-01-06 | Rheodyne, Lp | Dual random access, three-way rotary valve apparatus |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
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GB1041514A (en) * | 1964-04-28 | 1966-09-07 | Distillers Co Yeast Ltd | Improvements in or relating to fluid sampling valves |
JPS57198475U (en) * | 1981-06-12 | 1982-12-16 | ||
US4444066A (en) * | 1981-06-29 | 1984-04-24 | Beckman Instruments, Inc. | High pressure sample injector valve |
US4506558A (en) * | 1983-03-03 | 1985-03-26 | Rheodyne Incorporated | Injector with minimal flow-interrupt transient |
JPS60143279A (en) * | 1983-12-28 | 1985-07-29 | Shimadzu Corp | Selector valve of flow path |
JPS6256858A (en) * | 1985-09-05 | 1987-03-12 | Toyo Soda Mfg Co Ltd | Flaw passage changing device |
US5207109A (en) * | 1991-02-07 | 1993-05-04 | Rheodyne, Inc. | Internal-external sample injector |
US5465748A (en) * | 1994-05-24 | 1995-11-14 | Millipore Corporation | Sanitizable slider diaphragm valve |
US5803117A (en) * | 1996-06-10 | 1998-09-08 | Rheodyne, L.P. | Multi-route full sweep selection valve |
US6012448A (en) * | 1998-03-02 | 2000-01-11 | Arsenault; John W. | Fireplace draft regulator |
US6155123A (en) * | 1998-04-17 | 2000-12-05 | Rheodyne, L.P. | Multivalving sample injection system |
-
2008
- 2008-04-24 CA CA 2683944 patent/CA2683944A1/en not_active Abandoned
- 2008-04-24 JP JP2010508334A patent/JP5377477B2/en not_active Expired - Fee Related
- 2008-04-24 EP EP20080741862 patent/EP2147301A1/en not_active Withdrawn
- 2008-04-24 AU AU2008251098A patent/AU2008251098B2/en not_active Expired - Fee Related
- 2008-04-24 WO PCT/SE2008/000288 patent/WO2008140374A1/en active Application Filing
- 2008-04-24 US US12/597,826 patent/US8225817B2/en not_active Expired - Fee Related
- 2008-04-24 CN CN200880016262XA patent/CN101680861B/en not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1263481A (en) * | 1968-04-02 | 1972-02-09 | Beckman Instruments Inc | Sample injector for use in liquid chromatography |
US4625569A (en) * | 1984-01-17 | 1986-12-02 | Toyo Soda Manufacturing Co., Ltd. | Liquid injection device |
US4614204A (en) * | 1984-12-10 | 1986-09-30 | Uop Inc. | Rotary valve for interconnecting conduits in three groups |
US6012488A (en) * | 1998-09-17 | 2000-01-11 | Rheodyne, L.P. | Segmenting valve |
US6672336B2 (en) * | 2001-11-28 | 2004-01-06 | Rheodyne, Lp | Dual random access, three-way rotary valve apparatus |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2013533464A (en) * | 2010-05-20 | 2013-08-22 | バイオ−ラッド ラボラトリーズ,インコーポレイティド | Rotating cylindrical switching valve |
WO2013116285A1 (en) | 2012-02-01 | 2013-08-08 | Waters Technologies Corporation | Managing fluidic connections to microfluidic devices |
EP2809414A4 (en) * | 2012-02-01 | 2015-11-25 | Waters Technologies Corp | Managing fluidic connections to microfluidic devices |
US10866218B2 (en) | 2012-02-01 | 2020-12-15 | Waters Technologies Corporation | Managing fluidic connections to microfluidic devices |
EP2888595A4 (en) * | 2012-08-22 | 2016-04-13 | Ge Healthcare Bio Sciences Ab | Versatile rotary valve |
US9625044B2 (en) | 2012-08-22 | 2017-04-18 | Ge Healthcare Bio-Sciences Ab | Versatile rotary valve |
US10047869B2 (en) | 2012-08-22 | 2018-08-14 | Ge Healthcare Bio-Sciences Ab | Versatile rotary valve |
WO2015094095A1 (en) * | 2013-12-19 | 2015-06-25 | Ge Healthcare Bio-Sciences Ab | Rotary valve |
WO2015094096A1 (en) * | 2013-12-19 | 2015-06-25 | Ge Healthcare Bio-Sciences Ab | Rotary valve |
US10302603B2 (en) | 2013-12-19 | 2019-05-28 | Ge Healthcare Bio-Science Ab | Rotary valve |
US10309938B2 (en) | 2013-12-19 | 2019-06-04 | Ge Healthcare Bio-Sciences Ab | Rotary valve |
US10746708B2 (en) | 2015-03-30 | 2020-08-18 | Ge Healthcare Bio-Sciences Ab | Rotary valve and a chromatography system |
Also Published As
Publication number | Publication date |
---|---|
JP2010526976A (en) | 2010-08-05 |
EP2147301A1 (en) | 2010-01-27 |
AU2008251098A1 (en) | 2008-11-20 |
US8225817B2 (en) | 2012-07-24 |
JP5377477B2 (en) | 2013-12-25 |
CN101680861B (en) | 2012-10-10 |
AU2008251098B2 (en) | 2013-11-21 |
CN101680861A (en) | 2010-03-24 |
CA2683944A1 (en) | 2008-11-20 |
US20100058841A1 (en) | 2010-03-11 |
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