WO2008121183A3 - Method for diagnosis of physiological states by detecting patterns of volatile analytes - Google Patents

Method for diagnosis of physiological states by detecting patterns of volatile analytes Download PDF

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Publication number
WO2008121183A3
WO2008121183A3 PCT/US2008/001817 US2008001817W WO2008121183A3 WO 2008121183 A3 WO2008121183 A3 WO 2008121183A3 US 2008001817 W US2008001817 W US 2008001817W WO 2008121183 A3 WO2008121183 A3 WO 2008121183A3
Authority
WO
WIPO (PCT)
Prior art keywords
physiological
diagnosis
physiological states
detecting patterns
volatile analytes
Prior art date
Application number
PCT/US2008/001817
Other languages
French (fr)
Other versions
WO2008121183A2 (en
Inventor
Frank V Bright
Alexander N Cartwright
Venugopal Govindaraju
Wesley Hicks
Albert H Titus
Original Assignee
Univ New York State Res Found
Frank V Bright
Alexander N Cartwright
Venugopal Govindaraju
Wesley Hicks
Albert H Titus
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ New York State Res Found, Frank V Bright, Alexander N Cartwright, Venugopal Govindaraju, Wesley Hicks, Albert H Titus filed Critical Univ New York State Res Found
Priority to CA002677718A priority Critical patent/CA2677718A1/en
Priority to EP08779564A priority patent/EP2117430A2/en
Publication of WO2008121183A2 publication Critical patent/WO2008121183A2/en
Publication of WO2008121183A3 publication Critical patent/WO2008121183A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/52—Use of compounds or compositions for colorimetric, spectrophotometric or fluorometric investigation, e.g. use of reagent paper and including single- and multilayer analytical elements
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/08—Detecting, measuring or recording devices for evaluating the respiratory organs
    • A61B5/082—Evaluation by breath analysis, e.g. determination of the chemical composition of exhaled breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7264—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • A61B5/7267—Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems involving training the classification device
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/70—Mechanisms involved in disease identification
    • G01N2800/7023—(Hyper)proliferation
    • G01N2800/7028—Cancer

Abstract

Provided is a non-invasive method for identification of non-physiological, physiological or diseased states based on the volatiles in gas or biogas samples from individuals. The method uses a sensor array comprising a plurality of distinct sensors which differ from other sensors by the sensing molecules or the sol-gel holding material composition. In response to a combination of volatiles, a pattern of responses is generated which can be correlated to particular non-physiological, physiological or diseased state.
PCT/US2008/001817 2007-02-09 2008-02-11 Method for diagnosis of physiological states by detecting patterns of volatile analytes WO2008121183A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002677718A CA2677718A1 (en) 2007-02-09 2008-02-11 Method for diagnosis of physiological states by detecting patterns of volatile analytes
EP08779564A EP2117430A2 (en) 2007-02-09 2008-02-11 Method for diagnosis of physiological states by detecting patterns of volatile analytes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90067607P 2007-02-09 2007-02-09
US60/900,676 2007-02-09

Publications (2)

Publication Number Publication Date
WO2008121183A2 WO2008121183A2 (en) 2008-10-09
WO2008121183A3 true WO2008121183A3 (en) 2009-01-08

Family

ID=39808825

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/001817 WO2008121183A2 (en) 2007-02-09 2008-02-11 Method for diagnosis of physiological states by detecting patterns of volatile analytes

Country Status (3)

Country Link
EP (1) EP2117430A2 (en)
CA (1) CA2677718A1 (en)
WO (1) WO2008121183A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20160106935A1 (en) * 2014-10-17 2016-04-21 Qualcomm Incorporated Breathprint sensor systems, smart inhalers and methods for personal identification

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063637A (en) * 1995-12-13 2000-05-16 California Institute Of Technology Sensors for sugars and other metal binding analytes
US6589438B2 (en) * 1999-07-28 2003-07-08 The Research Foundation Of State University Of New York Method for making microsensor arrays for detecting analytes
US6602716B1 (en) * 1997-08-01 2003-08-05 Presens Precision Sensing Gmbh Method and device for referencing fluorescence intensity signals
US6746960B2 (en) * 1998-04-09 2004-06-08 California Institute Of Technology Electronic techniques for analyte detection
US20050065446A1 (en) * 2002-01-29 2005-03-24 Talton James D Methods of collecting and analyzing human breath
US20060154414A1 (en) * 2002-12-30 2006-07-13 Chhiu-Tsu Lin Sensor for detecting compounds
US20060174934A1 (en) * 2002-11-05 2006-08-10 Nanosolar, Inc. Optoelectronic device and frabrication method
US20070009968A1 (en) * 2005-07-08 2007-01-11 The Board Of Trustees Of The University Of Illinois Photonic crystal biosensor structure and fabrication method

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063637A (en) * 1995-12-13 2000-05-16 California Institute Of Technology Sensors for sugars and other metal binding analytes
US6602716B1 (en) * 1997-08-01 2003-08-05 Presens Precision Sensing Gmbh Method and device for referencing fluorescence intensity signals
US6746960B2 (en) * 1998-04-09 2004-06-08 California Institute Of Technology Electronic techniques for analyte detection
US6589438B2 (en) * 1999-07-28 2003-07-08 The Research Foundation Of State University Of New York Method for making microsensor arrays for detecting analytes
US20050065446A1 (en) * 2002-01-29 2005-03-24 Talton James D Methods of collecting and analyzing human breath
US20060174934A1 (en) * 2002-11-05 2006-08-10 Nanosolar, Inc. Optoelectronic device and frabrication method
US20060154414A1 (en) * 2002-12-30 2006-07-13 Chhiu-Tsu Lin Sensor for detecting compounds
US20070009968A1 (en) * 2005-07-08 2007-01-11 The Board Of Trustees Of The University Of Illinois Photonic crystal biosensor structure and fabrication method

Also Published As

Publication number Publication date
WO2008121183A2 (en) 2008-10-09
CA2677718A1 (en) 2008-10-09
EP2117430A2 (en) 2009-11-18

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