WO2008102772A1 - Nucleic acid amplification system - Google Patents

Nucleic acid amplification system Download PDF

Info

Publication number
WO2008102772A1
WO2008102772A1 PCT/JP2008/052758 JP2008052758W WO2008102772A1 WO 2008102772 A1 WO2008102772 A1 WO 2008102772A1 JP 2008052758 W JP2008052758 W JP 2008052758W WO 2008102772 A1 WO2008102772 A1 WO 2008102772A1
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid amplification
aperture
heat source
container
Prior art date
Application number
PCT/JP2008/052758
Other languages
French (fr)
Japanese (ja)
Inventor
Masahiro Kusumoto
Yutaka Takarada
Original Assignee
Toyo Boseki Kabushiki Kaisha
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Toyo Boseki Kabushiki Kaisha filed Critical Toyo Boseki Kabushiki Kaisha
Priority to JP2008528285A priority Critical patent/JP5381100B2/en
Publication of WO2008102772A1 publication Critical patent/WO2008102772A1/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B04—CENTRIFUGAL APPARATUS OR MACHINES FOR CARRYING-OUT PHYSICAL OR CHEMICAL PROCESSES
    • B04B—CENTRIFUGES
    • B04B15/00—Other accessories for centrifuges
    • B04B15/02—Other accessories for centrifuges for cooling, heating, or heat insulating
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
    • B01L2300/0838—Capillaries
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • B01L9/065—Test-tube stands; Test-tube holders specially adapted for capillary tubes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00346—Heating or cooling arrangements
    • G01N2035/00356—Holding samples at elevated temperature (incubation)

Abstract

A nucleic acid amplification system comprising a heat source by which a nucleic acid amplification container is heated, a housing which has an aperture, a shutter for opening and closing the aperture, and a centrifuge on which the nucleic acid amplification container is loaded and centrifuged, wherein the heat source is located in the housing, the nucleic acid amplification container is rotated by the centrifuge around a line passing through the aperture face of the aperture as the rotational axis, and the position of the centrifuge is fixed by the shutter in the case of closing the aperture. Further, the system has the heat source for heating the nucleic acid amplification container and a heat block for stimulating the nucleic acid amplification container to thereby dissociate a double-stranded nucleic acid. The heat source continuously heats the nucleic acid amplification container, while the heat block intermittently stimulates it while the heat source conducts the heating. Thus, a nucleic acid amplification system, whereby a nucleic acid amplification reaction can be conveniently carried out within a short time, is provided.
PCT/JP2008/052758 2007-02-22 2008-02-19 Nucleic acid amplification system WO2008102772A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2008528285A JP5381100B2 (en) 2007-02-22 2008-02-19 Nucleic acid amplification equipment

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007042643 2007-02-22
JP2007-042643 2007-02-22

Publications (1)

Publication Number Publication Date
WO2008102772A1 true WO2008102772A1 (en) 2008-08-28

Family

ID=39710049

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/052758 WO2008102772A1 (en) 2007-02-22 2008-02-19 Nucleic acid amplification system

Country Status (2)

Country Link
JP (1) JP5381100B2 (en)
WO (1) WO2008102772A1 (en)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013524790A (en) * 2010-04-20 2013-06-20 コーベット リサーチ プロプライエタリー リミテッド Temperature control method and apparatus
EP2687294A1 (en) * 2012-07-18 2014-01-22 Qiagen Instruments AG Rotor for a thermal cycler and thermal cycler
JP2015514561A (en) * 2012-02-03 2015-05-21 マイクロソニック システムズ インク．Ｍｉｃｒｏｓｏｎｉｃ Ｓｙｓｔｅｍｓ Ｉｎｃ． Apparatus for automated processing of fluid samples using ultrasound
CN109266547A (en) * 2018-11-27 2019-01-25 嘉兴领宇科技有限公司 Nucleic acid-extracting apparatus
CN110062659A (en) * 2017-01-25 2019-07-26 (株)优真世 The temprature control method of high speed nucleic acid amplifier and nucleic acid amplification reaction
CN112221545A (en) * 2020-12-10 2021-01-15 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device and application thereof
CN113684120A (en) * 2021-08-20 2021-11-23 圣湘生物科技股份有限公司 Nucleic acid detection apparatus and nucleic acid detection method
WO2022091584A1 (en) * 2020-10-26 2022-05-05 株式会社島津製作所 Container opening device, analysis device, container closing device, and reagent kit

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR102081480B1 (en) * 2017-01-25 2020-04-24 주식회사 유진셀 Device for high-speed amplification of nucleic acid molecules

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241884A (en) * 1984-05-15 1985-11-30 Tokyo Daigaku Automation cycling reaction apparatus and automatic analyzer using same
US5455175A (en) * 1990-06-04 1995-10-03 University Of Utah Research Foundation Rapid thermal cycling device
WO1998049340A1 (en) * 1997-04-30 1998-11-05 John Michael Corbett Temperature cycling device and method
JP2000511435A (en) * 1996-06-04 2000-09-05 ユニバーシティ オブ ユタ リサーチ ファウンデーション Systems and methods for performing and monitoring biological processes
JP2002539937A (en) * 1999-03-25 2002-11-26 アルファヘリックス・アクチボラゲット Homogenization of small volume mixtures by centrifugal force and heating
WO2003000428A1 (en) * 2001-06-21 2003-01-03 Alphahelix Ab Thermocycling device and rotor means therefor
JP2004033146A (en) * 2002-07-05 2004-02-05 Terametsukusu Kk Genetic amplification reaction monitor
JP2005516588A (en) * 2001-09-15 2005-06-09 アーラム バイオシステムズ インコーポレイテッド Nucleic acid sequence amplification method and apparatus using thermal convection
WO2005116202A1 (en) * 2004-05-27 2005-12-08 Universal Bio Research Co., Ltd. Reaction vessel, reaction measuring device, and liquid rotating treatment device

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0523226Y2 (en) * 1987-08-28 1993-06-15

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60241884A (en) * 1984-05-15 1985-11-30 Tokyo Daigaku Automation cycling reaction apparatus and automatic analyzer using same
US5455175A (en) * 1990-06-04 1995-10-03 University Of Utah Research Foundation Rapid thermal cycling device
JP2000511435A (en) * 1996-06-04 2000-09-05 ユニバーシティ オブ ユタ リサーチ ファウンデーション Systems and methods for performing and monitoring biological processes
JP2000512138A (en) * 1996-06-04 2000-09-19 ユニバーシティ オブ ユタ リサーチ ファウンデーション System and method for fluorescence monitoring of DNA amplification
WO1998049340A1 (en) * 1997-04-30 1998-11-05 John Michael Corbett Temperature cycling device and method
JP2002539937A (en) * 1999-03-25 2002-11-26 アルファヘリックス・アクチボラゲット Homogenization of small volume mixtures by centrifugal force and heating
WO2003000428A1 (en) * 2001-06-21 2003-01-03 Alphahelix Ab Thermocycling device and rotor means therefor
JP2005516588A (en) * 2001-09-15 2005-06-09 アーラム バイオシステムズ インコーポレイテッド Nucleic acid sequence amplification method and apparatus using thermal convection
JP2004033146A (en) * 2002-07-05 2004-02-05 Terametsukusu Kk Genetic amplification reaction monitor
WO2005116202A1 (en) * 2004-05-27 2005-12-08 Universal Bio Research Co., Ltd. Reaction vessel, reaction measuring device, and liquid rotating treatment device

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2013524790A (en) * 2010-04-20 2013-06-20 コーベット リサーチ プロプライエタリー リミテッド Temperature control method and apparatus
JP2015514561A (en) * 2012-02-03 2015-05-21 マイクロソニック システムズ インク．Ｍｉｃｒｏｓｏｎｉｃ Ｓｙｓｔｅｍｓ Ｉｎｃ． Apparatus for automated processing of fluid samples using ultrasound
EP2687294A1 (en) * 2012-07-18 2014-01-22 Qiagen Instruments AG Rotor for a thermal cycler and thermal cycler
CN110062659A (en) * 2017-01-25 2019-07-26 (株)优真世 The temprature control method of high speed nucleic acid amplifier and nucleic acid amplification reaction
US11173491B2 (en) 2017-01-25 2021-11-16 U-gene & Cell Co. Apparatus for high-speed nucleic acid amplification and method for temperature control of nucleic acid amplification reaction
CN109266547A (en) * 2018-11-27 2019-01-25 嘉兴领宇科技有限公司 Nucleic acid-extracting apparatus
WO2022091584A1 (en) * 2020-10-26 2022-05-05 株式会社島津製作所 Container opening device, analysis device, container closing device, and reagent kit
CN112221545A (en) * 2020-12-10 2021-01-15 天津德祥生物技术有限公司 Multi-channel microfluidic sample adding device and application thereof
CN113684120A (en) * 2021-08-20 2021-11-23 圣湘生物科技股份有限公司 Nucleic acid detection apparatus and nucleic acid detection method

Also Published As

Publication number Publication date
JPWO2008102772A1 (en) 2010-05-27
JP5381100B2 (en) 2014-01-08

Similar Documents

Publication Publication Date Title
WO2008102772A1 (en) Nucleic acid amplification system
WO2010113150A3 (en) An apparatus, system and method for preventing biological contamination to materials during storage using pulsed electrical energy
EP3653139A3 (en) Surgical tool with an aseptic power module that enters a specific operating state based on the type of handpiece to which the module is attached
GB0510026D0 (en) A vehicle battery temperature control method and system
MY172344A (en) Electronic cigarette
WO2015131087A8 (en) A system for tissue manipulation
WO2014068508A3 (en) Method and device for thawing biological material
DE602004009142D1 (en) Device for controlling the charging process with cycle memory
WO2009014034A1 (en) Light irradiation beauty appliance
MX357321B (en) Hair styling apparatus.
WO2006060566A3 (en) An apparatus to automatically lyse a sample
NZ604240A (en) Heat transfer apparatus and container
WO2008123288A1 (en) Trap apparatus, exhaust system, and treating system using the same
TWI367679B (en) Temperature setting method for heat treatment plate, temperature setting program, computer-readable recording medium capable of storing program, and temperature setting device for heat treatment plate
MX2013007357A (en) An aerosol generating system having means for determining depletion of a liquid substrate.
EP2799781A3 (en) Cooking apparatus
RU2013123489A (en) METHOD FOR MANAGING PANS FOR RICE COOKING UNDER PRESSURE AND A CASING PAN FOR IMPLEMENTING SUCH METHOD
WO2012090159A3 (en) Methods and devices for cooking rice
WO2008089078A3 (en) Methods and apparatus for weapon fuze
SG146523A1 (en) Systems and methods for providing localized heat treatment of gas turbine components
WO2009091145A3 (en) Cooker and controlling method for the same
WO2015020828A8 (en) Self-warming peritoneal dialysis solution bag
MX2017000391A (en) Dna amplification technology.
EP3790103A4 (en) Battery pack heater and control method for dual-vehicle heating
WO2008019052A3 (en) Methods and compositions for identifying biomarkers

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2008528285

Country of ref document: JP

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08711582

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08711582

Country of ref document: EP

Kind code of ref document: A1