WO2008092895A3 - Vorrichtung und verfahren zur bestimmung der stoffmenge in kleinen kavitäten - Google Patents
Vorrichtung und verfahren zur bestimmung der stoffmenge in kleinen kavitäten Download PDFInfo
- Publication number
- WO2008092895A3 WO2008092895A3 PCT/EP2008/051131 EP2008051131W WO2008092895A3 WO 2008092895 A3 WO2008092895 A3 WO 2008092895A3 EP 2008051131 W EP2008051131 W EP 2008051131W WO 2008092895 A3 WO2008092895 A3 WO 2008092895A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- volumes
- substance
- samples
- cavities
- individual cavities
- Prior art date
Links
- 239000000126 substance Substances 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 238000009529 body temperature measurement Methods 0.000 abstract 1
- 238000011156 evaluation Methods 0.000 abstract 1
- 238000005259 measurement Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
- G01F23/00—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm
- G01F23/22—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water
- G01F23/28—Indicating or measuring liquid level or level of fluent solid material, e.g. indicating in terms of volume or indicating by means of an alarm by measuring physical variables, other than linear dimensions, pressure or weight, dependent on the level to be measured, e.g. by difference of heat transfer of steam or water by measuring the variations of parameters of electromagnetic or acoustic waves applied directly to the liquid or fluent solid material
- G01F23/284—Electromagnetic waves
- G01F23/292—Light, e.g. infrared or ultraviolet
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/143—Quality control, feedback systems
- B01L2200/147—Employing temperature sensors
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1861—Means for temperature control using radiation
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Electromagnetism (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Thermal Sciences (AREA)
- Fluid Mechanics (AREA)
- General Physics & Mathematics (AREA)
- Investigating Or Analyzing Materials Using Thermal Means (AREA)
- Optical Measuring Cells (AREA)
- Investigating Or Analysing Materials By Optical Means (AREA)
- Sampling And Sample Adjustment (AREA)
Abstract
Beschrieben wird ein Verfahren und eine Vorrichtung zur gleichzeitigen Bestimmung der Masse, des Volumens oder der Art von Stoffproben in zahlreichen kleinen Kavitäten (2), insbesondere von Wells in Mikrotiterplatten. Das Verfahren sieht vor, dass den teilweise oder vollständig mit Proben gefüllten Kavitäten Energie durch eine Energiequelle (5) zugeführt wird. Hierdurch erwärmen sich die Proben in Abhängigkeit von ihrer Masse mehr oder minder stark. Die Bestimmung der Stoffmenge in den einzelnen Kavitäten wird somit auf eine Temperaturmessung zurückgeführt. Das parallele Erfassen der Probentemperatur in den einzelnen Kavitäten kann vorteilhafterweise durch eine Infrarotkamera als Detektor (6) erfolgen. Das Gesamtsystem, das im Wesentlichen aus einer Energiequelle und einem Detektor besteht, kann durch die Implementierung geeigneter Kalibrier- und Messroutinen in einer Auswerteeinheit (7) so aufgebaut werden, dass die Stoffmengen in den einzelnen Kavitäten direkt angezeigt werden.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12/524,739 US20100218600A1 (en) | 2007-01-31 | 2008-01-30 | Device and method for determining the quantity of substance in small cavities |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE102007005618A DE102007005618A1 (de) | 2007-01-31 | 2007-01-31 | Vorrichtung und Verfahren zur Bestimmung der Stoffmenge in kleinen Kavitäten |
DE102007005618.6 | 2007-01-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2008092895A2 WO2008092895A2 (de) | 2008-08-07 |
WO2008092895A3 true WO2008092895A3 (de) | 2008-10-30 |
Family
ID=39521993
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2008/051131 WO2008092895A2 (de) | 2007-01-31 | 2008-01-30 | Vorrichtung und verfahren zur bestimmung der stoffmenge in kleinen kavitäten |
Country Status (3)
Country | Link |
---|---|
US (1) | US20100218600A1 (de) |
DE (1) | DE102007005618A1 (de) |
WO (1) | WO2008092895A2 (de) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2012173118A (ja) * | 2011-02-21 | 2012-09-10 | Fujitsu Ltd | 温度計測システムおよび温度計測方法 |
US8550704B2 (en) | 2011-11-16 | 2013-10-08 | Toyota Motor Engineering & Manufacturing North America, Inc. | Method for detecting automobile differential fill omission |
GB201319759D0 (en) | 2013-11-08 | 2013-12-25 | Thomsen Lars | Device and method for heating a fluid chamber |
EP3302248A4 (de) | 2015-06-01 | 2019-01-30 | Digital Hospital, Inc. | Dosierungsbestätigungsvorrichtung |
DE102015214414B4 (de) * | 2015-07-29 | 2020-10-22 | Berthold Technologies Gmbh & Co. Kg | Verfahren und System zur Ermittlung biologischer Eigenschaften von Proben |
DE102016117754B4 (de) | 2016-09-21 | 2019-03-21 | Netzsch-Gerätebau GmbH | Verfahren zum Kalibrieren einer Vorrichtung zur thermischen Analyse von Proben |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020070208A1 (en) * | 2000-12-12 | 2002-06-13 | 3-Dimensional Pharmaceuticals, Inc. | Microtiter plate with integral heater |
US20020155036A1 (en) * | 1998-08-13 | 2002-10-24 | Symyx Technologies, Inc. | Multi-temperature modular reactor and method of using same |
US20020197731A1 (en) * | 1996-10-09 | 2002-12-26 | Symyx Technologies, Inc. | Infrared spectroscopy imaging of libraries |
US20030082633A1 (en) * | 2000-10-03 | 2003-05-01 | Martin Mark T. | Directed microwave chemistry |
US20040175760A1 (en) * | 1996-10-09 | 2004-09-09 | Symyx Technologies, Inc. | Analysis of chemical data from images |
US20050028587A1 (en) * | 2003-01-27 | 2005-02-10 | Baer Thomas M. | Apparatus and method for heating microfluidic volumes and moving fluids |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3016095B2 (ja) * | 1990-11-29 | 2000-03-06 | セイコーインスツルメンツ株式会社 | 熱重量測定装置 |
JPH05157684A (ja) | 1991-12-02 | 1993-06-25 | Seikagaku Kogyo Co Ltd | 吸光光度計 |
CH687592A5 (de) | 1993-10-18 | 1997-01-15 | Eidgenoess Munitionsfab Thun | Mehrgefaessanordnung zur Instrumental-Analyse. |
US6063633A (en) * | 1996-02-28 | 2000-05-16 | The University Of Houston | Catalyst testing process and apparatus |
DE10225994B3 (de) * | 2002-06-12 | 2004-03-11 | Robert Bosch Gmbh | Vorrichtung und Verfahren zur Prüfung zahlreicher, verschiedener Materialproben |
US7279131B2 (en) * | 2004-07-01 | 2007-10-09 | Uop Llc | Method and apparatus for mass analysis of samples |
-
2007
- 2007-01-31 DE DE102007005618A patent/DE102007005618A1/de not_active Ceased
-
2008
- 2008-01-30 US US12/524,739 patent/US20100218600A1/en not_active Abandoned
- 2008-01-30 WO PCT/EP2008/051131 patent/WO2008092895A2/de active Application Filing
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020197731A1 (en) * | 1996-10-09 | 2002-12-26 | Symyx Technologies, Inc. | Infrared spectroscopy imaging of libraries |
US20040175760A1 (en) * | 1996-10-09 | 2004-09-09 | Symyx Technologies, Inc. | Analysis of chemical data from images |
US20020155036A1 (en) * | 1998-08-13 | 2002-10-24 | Symyx Technologies, Inc. | Multi-temperature modular reactor and method of using same |
US20030082633A1 (en) * | 2000-10-03 | 2003-05-01 | Martin Mark T. | Directed microwave chemistry |
US20020070208A1 (en) * | 2000-12-12 | 2002-06-13 | 3-Dimensional Pharmaceuticals, Inc. | Microtiter plate with integral heater |
US20050028587A1 (en) * | 2003-01-27 | 2005-02-10 | Baer Thomas M. | Apparatus and method for heating microfluidic volumes and moving fluids |
Also Published As
Publication number | Publication date |
---|---|
DE102007005618A1 (de) | 2008-08-07 |
WO2008092895A2 (de) | 2008-08-07 |
US20100218600A1 (en) | 2010-09-02 |
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