WO2008076557A3 - Detecting cyp2d6 alleles - Google Patents

Detecting cyp2d6 alleles Download PDF

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Publication number
WO2008076557A3
WO2008076557A3 PCT/US2007/084697 US2007084697W WO2008076557A3 WO 2008076557 A3 WO2008076557 A3 WO 2008076557A3 US 2007084697 W US2007084697 W US 2007084697W WO 2008076557 A3 WO2008076557 A3 WO 2008076557A3
Authority
WO
WIPO (PCT)
Prior art keywords
alleles
cyp2d6 alleles
detecting
detecting cyp2d6
cyp2d6
Prior art date
Application number
PCT/US2007/084697
Other languages
French (fr)
Other versions
WO2008076557A2 (en
Inventor
David A Mrazek
Iii John L Black
Dennis J O'kane
Original Assignee
Mayo Foundation
David A Mrazek
Iii John L Black
Dennis J O'kane
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mayo Foundation, David A Mrazek, Iii John L Black, Dennis J O'kane filed Critical Mayo Foundation
Publication of WO2008076557A2 publication Critical patent/WO2008076557A2/en
Publication of WO2008076557A3 publication Critical patent/WO2008076557A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

This document relates to methods and materials involved in detecting CYP2D6 alleles or CYP2D6 - CYP2D7 recombinant alleles in mammals (e.g., humans).
PCT/US2007/084697 2006-11-14 2007-11-14 Detecting cyp2d6 alleles WO2008076557A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US85908106P 2006-11-14 2006-11-14
US60/859,081 2006-11-14
US90586207P 2007-03-08 2007-03-08
US60/905,862 2007-03-08

Publications (2)

Publication Number Publication Date
WO2008076557A2 WO2008076557A2 (en) 2008-06-26
WO2008076557A3 true WO2008076557A3 (en) 2008-08-21

Family

ID=39536942

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/084697 WO2008076557A2 (en) 2006-11-14 2007-11-14 Detecting cyp2d6 alleles

Country Status (1)

Country Link
WO (1) WO2008076557A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN113755578A (en) * 2021-09-09 2021-12-07 上海普然生物科技有限公司 Detection kit for ondansetron and tropisetron metabolic markers and detection method and application thereof

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281755A2 (en) * 2001-07-31 2003-02-05 Pfizer Products Inc. Variants of the human cyp2d6 gene
WO2004009760A2 (en) * 2002-07-18 2004-01-29 Bioventures, Inc. Cytochrome p450 genetic variations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1281755A2 (en) * 2001-07-31 2003-02-05 Pfizer Products Inc. Variants of the human cyp2d6 gene
WO2004009760A2 (en) * 2002-07-18 2004-01-29 Bioventures, Inc. Cytochrome p450 genetic variations

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
BODIN L. ET AL.: "Determination of Cytochrome P450 2D6 (CYP2D6) Gene Copy Number by Real-Time Quantitative PCR", J. BIOMED. BIOTECHNOL., vol. 2005, no. 3, 2005, pages 248 - 253 *
DATABASE GENBANK [online] 17 October 2006 (2006-10-17), accession no. NCBI Database accession no. (BX247885) *
DATABASE GENBANK [online] 19 October 2005 (2005-10-19), accession no. NCBI Database accession no. (DQ211353) *
JI L. ET AL.: "Genetic Polymorphisms of CYP2D6 in Chinese Mainland", CHIN. MED. J., vol. 115, no. 12, December 2002 (2002-12-01), pages 1780 - 1784 *
ROBERTS R.L. ET AL.: "Rapid Detection of Common Cytochrome P450 2D6 Alleles in Caucasians", CLIN. CHIM. ACTA, vol. 366, April 2006 (2006-04-01), pages 348 - 351, XP005320431 *

Also Published As

Publication number Publication date
WO2008076557A2 (en) 2008-06-26

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