WO2008061966A3 - New use of flibanserin - Google Patents

New use of flibanserin Download PDF

Info

Publication number
WO2008061966A3
WO2008061966A3 PCT/EP2007/062527 EP2007062527W WO2008061966A3 WO 2008061966 A3 WO2008061966 A3 WO 2008061966A3 EP 2007062527 W EP2007062527 W EP 2007062527W WO 2008061966 A3 WO2008061966 A3 WO 2008061966A3
Authority
WO
WIPO (PCT)
Prior art keywords
flibanserin
new use
ht2b
medicament
preparing
Prior art date
Application number
PCT/EP2007/062527
Other languages
French (fr)
Other versions
WO2008061966A8 (en
WO2008061966A2 (en
Inventor
Angelo Ceci
Marcus Schindler
Original Assignee
Boehringer Ingelheim Int
Boehringer Ingelheim Pharma
Angelo Ceci
Marcus Schindler
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Int, Boehringer Ingelheim Pharma, Angelo Ceci, Marcus Schindler filed Critical Boehringer Ingelheim Int
Publication of WO2008061966A2 publication Critical patent/WO2008061966A2/en
Publication of WO2008061966A3 publication Critical patent/WO2008061966A3/en
Publication of WO2008061966A8 publication Critical patent/WO2008061966A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)

Abstract

The invention relates to the use of flibanserin for preparing a medicament for treating diseases in which the use of therapeutic effective amounts of compounds displaying affinity for the 5-HT2B-receptor display a therapeutic benefit.
PCT/EP2007/062527 2006-11-22 2007-11-20 New use of flibanserin WO2008061966A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP06124575 2006-11-22
EP06124575.9 2006-11-22

Publications (3)

Publication Number Publication Date
WO2008061966A2 WO2008061966A2 (en) 2008-05-29
WO2008061966A3 true WO2008061966A3 (en) 2008-07-10
WO2008061966A8 WO2008061966A8 (en) 2008-09-04

Family

ID=39201544

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2007/062527 WO2008061966A2 (en) 2006-11-22 2007-11-20 New use of flibanserin

Country Status (1)

Country Link
WO (1) WO2008061966A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2011004284A (en) * 2008-10-22 2011-06-21 Sam Amer & Co Inc Method for treating pulmonary arterial hypertension.
CN103467596A (en) * 2012-06-06 2013-12-25 北京大学 Novel target spot for treatment of pulmonary arterial hypertension

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1518858A1 (en) * 2001-08-02 2005-03-30 BIDACHEM S.p.A. Stable polymorph of flibanserin, technical process for its preparation and the use thereof for preparing medicaments
US20050222176A1 (en) * 2003-03-31 2005-10-06 Dhanoa Dale S Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1518858A1 (en) * 2001-08-02 2005-03-30 BIDACHEM S.p.A. Stable polymorph of flibanserin, technical process for its preparation and the use thereof for preparing medicaments
US20050222176A1 (en) * 2003-03-31 2005-10-06 Dhanoa Dale S Piperidinylamino-thieno[2,3-D] pyrimidine compounds
US20060120972A1 (en) * 2004-11-09 2006-06-08 Peter Engels 9-(N-methyl-piperidyliden-4)-thioxanthene for treatment of pulmonary hypertension

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
BORSINI F ET AL: "BEHAVIORAL EFFECT OF FLIBANSERIN (BIMT 17)", EUROPEAN JOURNAL OF PHARMACOLOGY, AMSTERDAM, NL, vol. 64, no. 1, September 1999 (1999-09-01), pages 137 - 146, XP001055977, ISSN: 0014-2999 *
LONG LU ET AL: "Serotonin increases susceptibility to pulmonary hypertension in BMPR2-deficient mice.", CIRCULATION RESEARCH 31 MAR 2006, vol. 98, no. 6, 31 March 2006 (2006-03-31), pages 818 - 827, XP002474423, ISSN: 1524-4571 *

Also Published As

Publication number Publication date
WO2008061966A8 (en) 2008-09-04
WO2008061966A2 (en) 2008-05-29

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