WO2008018090A3 - An improved process for the preparation of zolmitriptan - Google Patents

An improved process for the preparation of zolmitriptan Download PDF

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Publication number
WO2008018090A3
WO2008018090A3 PCT/IN2007/000328 IN2007000328W WO2008018090A3 WO 2008018090 A3 WO2008018090 A3 WO 2008018090A3 IN 2007000328 W IN2007000328 W IN 2007000328W WO 2008018090 A3 WO2008018090 A3 WO 2008018090A3
Authority
WO
WIPO (PCT)
Prior art keywords
zolmitriptan
preparation
improved process
excluded
disclosed
Prior art date
Application number
PCT/IN2007/000328
Other languages
French (fr)
Other versions
WO2008018090A2 (en
Inventor
Amit Rohatgi
Purna Chandra Ray
Vutukuru Naga Chandra Sekhar
Aviraboina Siva Prasad
Original Assignee
Matrix Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Matrix Laboratories Ltd filed Critical Matrix Laboratories Ltd
Publication of WO2008018090A2 publication Critical patent/WO2008018090A2/en
Publication of WO2008018090A3 publication Critical patent/WO2008018090A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Disclosed herein the process for producing pure' Zolmitriptan employing improved reaction conditions which excluded the use of column chromatography.
PCT/IN2007/000328 2006-08-09 2007-08-06 An improved process for the preparation of zolmitriptan WO2008018090A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1422CH2006 2006-08-09
IN1422/CHE/2006 2006-08-09

Publications (2)

Publication Number Publication Date
WO2008018090A2 WO2008018090A2 (en) 2008-02-14
WO2008018090A3 true WO2008018090A3 (en) 2009-09-24

Family

ID=39033393

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2007/000328 WO2008018090A2 (en) 2006-08-09 2007-08-06 An improved process for the preparation of zolmitriptan

Country Status (1)

Country Link
WO (1) WO2008018090A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101883766A (en) * 2007-10-03 2010-11-10 基因里克斯(英国)有限公司 Process for the preparation of zolmitriptan, salts and solvates thereof
US9006453B2 (en) 2011-09-02 2015-04-14 Emcure Pharmaceuticals Limited Process for preparation of zolmitriptan
CN103275075B (en) * 2013-06-24 2015-01-07 成都天台山制药有限公司 Zolmitriptan and preparation method thereof
CN113620897A (en) * 2021-09-06 2021-11-09 南京杰运医药科技有限公司 Preparation method of oxazolidinone compound

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466699A (en) * 1990-06-07 1995-11-14 Burroughs Wellcome Co. Indolyl compounds for treating migraine
WO1997006162A1 (en) * 1995-08-07 1997-02-20 Zeneca Limited One pot synthesis of 2-oxazolidinone derivatives
WO2006055964A2 (en) * 2004-11-19 2006-05-26 Teva Pharmaceutical Industries Ltd. Zolmitriptan crystal forms
WO2008007390A2 (en) * 2006-07-10 2008-01-17 Natco Pharma Limited An improved process for purification of zolmitriptan

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5466699A (en) * 1990-06-07 1995-11-14 Burroughs Wellcome Co. Indolyl compounds for treating migraine
WO1997006162A1 (en) * 1995-08-07 1997-02-20 Zeneca Limited One pot synthesis of 2-oxazolidinone derivatives
WO2006055964A2 (en) * 2004-11-19 2006-05-26 Teva Pharmaceutical Industries Ltd. Zolmitriptan crystal forms
WO2008007390A2 (en) * 2006-07-10 2008-01-17 Natco Pharma Limited An improved process for purification of zolmitriptan

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
AMMAZZALORSO, A. ET AL.: "Synthesis and antibacterial evaluation of oxazolidin-2-ones structurally related to linezolid", IL FARMACO, vol. 59, 2004, pages 685 - 690, XP004547500, DOI: doi:10.1016/j.farmac.2004.05.002 *

Also Published As

Publication number Publication date
WO2008018090A2 (en) 2008-02-14

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