WO2007139212A1 - Analyseur automatique - Google Patents

Analyseur automatique Download PDF

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Publication number
WO2007139212A1
WO2007139212A1 PCT/JP2007/061188 JP2007061188W WO2007139212A1 WO 2007139212 A1 WO2007139212 A1 WO 2007139212A1 JP 2007061188 W JP2007061188 W JP 2007061188W WO 2007139212 A1 WO2007139212 A1 WO 2007139212A1
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WO
WIPO (PCT)
Prior art keywords
lane
sample
unit
transport
sample rack
Prior art date
Application number
PCT/JP2007/061188
Other languages
English (en)
Japanese (ja)
Inventor
Takashi Amemiya
Original Assignee
Olympus Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olympus Corporation filed Critical Olympus Corporation
Publication of WO2007139212A1 publication Critical patent/WO2007139212A1/fr

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/0092Scheduling
    • G01N35/0095Scheduling introducing urgent samples with priority, e.g. Short Turn Around Time Samples [STATS]

Definitions

  • the present invention relates to an automatic analyzer that automatically performs analyzes such as biochemical analysis and immunological tests.
  • the automatic analyzer has a sample supply unit, an analysis unit, and a data processing unit.
  • the sample supply unit sequentially supplies sample racks loaded with sample containers.
  • This sample container contains a sample.
  • the analysis unit has a reaction tank and a reagent cold storage.
  • the reaction tank is equipped with a cuvette wheel and a measurement optical system inside, and a reagent bottle containing a reagent that reacts with the sample is stored in the reagent cooler.
  • the cuvette wheel contains a cuvette (reaction container), which dispenses the reagent from the reagent bottle and dispenses the specimen from the specimen container.
  • the absorbance of the test solution (mixed solution consisting of the reagent and the sample) reacted in the cuvette is measured using a measurement optical system. Then, the data processing unit obtains the analysis result from the measured absorbance.
  • the sample rack on which the sample container is mounted on the transport line is stopped, and the sample in the sample container is dispensed to the analysis unit (for example, see Patent Document 1). ).
  • Patent Document 1 Japanese Patent Laid-Open No. 5-26882
  • Patent Document 2 Japanese Patent Laid-Open No. 11-316238
  • the emergency sample rack and the re-examination sample rack are transported on a transport line different from the transport line of the normal test sample rack, thereby improving the efficiency of rack transport.
  • the analyzer itself becomes large.
  • the present invention has been made in view of the above, and when it is desired to transport a subsequent emergency sample rack holding a sample having a high analysis priority first, the preceding sample rack is transported as a transport line marker.
  • the purpose is to provide an automatic analyzer that can shorten the sample rack transport time and efficiently transport the rack by temporarily evacuating and transporting the subsequent emergency sample rack first. .
  • an automatic analyzer includes a plurality of analyzers for analyzing a test solution obtained by reacting a sample and a reagent,
  • the automatic analyzer that transports the sample racks it holds to the suction position of each analyzer via the main lane, it is provided in the middle of the main lane and shifts in a direction perpendicular to the transport direction of the main lane.
  • a lane shift unit having a bridge lane and the lane shift unit is shifted in a direction perpendicular to the transport direction, and a desired bridge lane among the bridge lanes is combined with the main lane to
  • the sample rack existing in the bridging lane is withdrawn from the transport line force, and the emergency sample rack is moved by the other bridging lane.
  • a transfer control unit that controls the lane driving unit so as to bridge the main lane.
  • the automatic analyzer according to the present invention is the above invention, wherein the transfer control unit is After the emergency sample rack is bridged to the main lane, the lane driving unit is controlled so that the other sample racks withdrawn are returned to the transport line.
  • the lane shift unit is provided at a suction position of an analyzer set in the transport line.
  • the automatic analyzer according to the present invention is characterized in that, in the above invention, the lane shift unit has at least one bridging lane with respect to the number of the main lanes.
  • An automatic analyzer automatically transports a sample rack holding a test solution to be tested to a predetermined analyzer position among a plurality of analyzers by a transport lane.
  • a lane shift unit provided in the middle of the transport lane and having a plurality of bridging lanes that shift in a direction crossing the transport direction of the transport lane, and driving the lane shift unit to drive the plurality of bridging lanes
  • a lane driving unit that forms a transport line for the sample rack by combining a desired bridging lane of the lane with the transport lane, and an emergency sample rack having a high analysis priority are transported in advance.
  • the sample rack that has been transported is temporarily retracted out of the transport line by shifting the bridging lane, and is different from the bridging lane.
  • a transfer control unit that controls the lane driving unit so as to be positioned on the transfer line.
  • the automatic analyzer according to the present invention is characterized in that, in the above invention, the plurality of bridging lanes are juxtaposed in parallel with the transport lane.
  • the automatic analyzer includes a lane shift unit having at least two bridging lanes that shift in a direction orthogonal to the transport direction of the main lane in the middle of the main lane transporting the sample rack.
  • a lane shift unit having at least two bridging lanes that shift in a direction orthogonal to the transport direction of the main lane in the middle of the main lane transporting the sample rack.
  • FIG. 1 is a schematic configuration diagram showing a configuration of an automatic analyzer according to the present invention.
  • FIG. 2 is a front view showing the configuration of the automatic analyzer according to the present invention.
  • FIG. 3 is an enlarged plan view of the analyzer shown in FIG.
  • FIG. 4 is an enlarged plan view showing the configuration of the sample transport unit and the lane shift unit shown in FIG. 2.
  • FIG. 5 is a block diagram showing the configuration of the control system of the automatic analyzer according to the present invention.
  • FIG. 6 is a flowchart for explaining the sample rack transport operation of the automatic analyzer according to the present invention.
  • the automatic analyzer according to the present invention can be applied to an automatic analyzer that automatically performs analyzes such as biochemical analysis and immunological tests.
  • biochemical analyzer used for clinical tests and the like is used here. Will be described as an example.
  • FIG. 1 is a block diagram showing a schematic configuration of an automatic analyzer according to the present invention
  • FIG. 2 is a front view showing the configuration of the automatic analyzer according to the present invention
  • FIG. 3 is an enlarged plan view of the analyzer shown in FIG.
  • FIG. 4 is an enlarged plan view showing the configuration of the sample transport unit and the lane shift unit shown in FIG.
  • the automatic analyzer 1 includes a plurality of analyzers 1A to: LC, a sample supply unit 4 that is a sample supply unit, and a data processing unit 7.
  • the automatic analyzer 1 according to this embodiment includes three analyzers 1A to LC arranged in parallel.
  • the LC includes a reagent storage unit 2 and a reaction unit 3, respectively.
  • one analyzer 1B is shown enlarged as a representative.
  • the reagent storage unit 2 has a circular table 21.
  • the table 21 is rotatably provided around the center 21a and is rotated by a driving means (not shown).
  • the table 21 holds a plurality of reagent containers 22 containing reagents in the circumferential direction.
  • the reagent container 22 moves around the center 21 a as the table 21 rotates.
  • Ma The reagent storage unit 2 has a case (not shown) that covers the periphery of the table 21, and cools the reagent in the reagent container 22 by cooling the inside of the case to a predetermined temperature.
  • the reagent storage unit 2 includes a first reagent storage unit 2A and a second reagent storage unit 2B in order to store the first reagent and the second reagent, respectively.
  • the first reagent storage unit 2A is arranged in a container holding unit 31 of the reaction unit 3 described later, and the second reagent storage unit 2B is arranged outside the container holding unit 31 of the reaction unit 3.
  • the reagent container 22 is affixed with a bar code label having various information such as the type, amount, and lot number of the stored reagent.
  • the reagent storage unit 2 (1A, 2B) is provided with a barcode reader (not shown) that reads the barcode of the reagent container 22.
  • the reagent container 22 is a synthetic resin container having a fan-shaped outer shape in a plan view, and connecting the fan shapes in the vertical direction, and has an opening on the upper surface thereof.
  • the opening of the reagent container 22 is sealed with a stopper when not in use, and the stopper is removed when the reagent container 22 is stored in the reagent storage unit 2.
  • the reaction unit 3 includes a cylindrical container holding unit (cuvette wheel) 31.
  • the container holding part 31 is rotatably provided around the center 31a and is rotated by a driving means (not shown).
  • the container holding part 31 has a plurality of recesses (not shown) along its circumferential direction. Each recess holds a reaction container (cuvette) 32 for mixing the reagent and the specimen.
  • the container holding part 31 has a light shielding member (not shown) between the concave parts adjacent to each other in the circumferential direction, and the adjacent reaction containers 32 are shielded from light.
  • the container holding part 31 is provided with openings (not shown) penetrating in the radial direction in the respective recesses, and the reaction container 32 is exposed through the openings.
  • the reaction unit 3 has a case (not shown) that covers the periphery of the container holding unit 31, and the temperature inside the case is kept at a predetermined temperature (eg, 37 ° C.) as a thermostatic bath, thereby Incubate the reaction solution in which the reagent and sample reacted.
  • a predetermined temperature eg, 37 ° C.
  • the reaction vessel 32 is a bottomed rectangular tube-like vessel having an open top, and is a material that transmits 80% or more of light contained in analysis light described later (for example, glass containing heat-resistant glass, Synthetic resin such as cyclic olefin and polystyrene).
  • the reaction vessel 32 is used as a photometric region in which the lower peripheral wall transmits the analysis light. This photometric region defines the thickness of the reaction liquid in the direction in which the light for measuring the optical characteristics of the reaction liquid is transmitted between the peripheral walls.
  • the reaction unit 3 is provided with an analysis optical system 33.
  • the analysis optical system 33 includes a light source 331, a spectroscopic unit 332, and a photometric sensor 333.
  • the light source 331 emits analysis light (for example, 340 to 800 nm) for analyzing the reaction liquid in the reaction vessel 32.
  • This analysis light passes through the opening of the container holding part 31 in the reaction part 3 and passes through the reaction solution in the photometric region of the reaction container 32.
  • the spectroscopic unit 332 is located on the optical axis of the light emitted from the light source 331 and separates the analysis light transmitted through the reaction solution toward the photometric sensor 333.
  • the photometric sensor 333 measures the analysis light (parallel light) split by the spectroscopic unit 332.
  • the reaction section 3 is provided with a stirring section and a reaction container cleaning section.
  • the stirring unit is for mixing the reagent in the reaction container 32 and the specimen, and includes a part in which a stirring bar is inserted into the reaction container 32 and a non-contact type using ultrasonic waves.
  • a stir bar cleaning section for cleaning the stir bar is required.
  • the reaction vessel cleaning section is for cleaning the inside of the reaction vessel 32. For example, the reaction solution in the reaction vessel 32 is sucked and discharged, and then the washing solution is repeatedly injected and discharged into the reaction vessel 32. Further, the inside of the reaction vessel 32 is then dried and wiped off.
  • a reagent dispensing unit 5 is provided in the vicinity of the reaction unit 3.
  • the reagent dispensing unit 5 here is provided between the first reagent dispensing unit 5A provided in the vicinity of the reaction unit 3 on the adjacent analyzer 1C side, and between the second reagent storage unit 2B and the reaction unit 3.
  • the reagent dispensing unit 5 has an arm 51 and a probe 52.
  • the arm 51 is provided with a base end attached to the upper end of a central shaft 51a erected in the vertical direction and extending in the horizontal direction.
  • the arm 51 rotates around the central axis 51 a by the rotation of the central axis 51 a driven by the driving means 53.
  • the arm 51 moves to a predetermined position of the reagent storage unit 2 or a predetermined position of the reaction unit 3 by rotation. Further, the arm 51 moves in the vertical direction by the vertical movement of the central shaft 51a driven by the driving means 53.
  • the probe 52 dispenses a reagent and is attached to the distal end portion of the arm 51 with the distal end directed downward. That is, the reagent dispensing unit 5 moves the probe 52 by moving the position of the tip of the arm 51 and moving up and down, sucks the reagent from the reagent container 22 in the reagent storage unit 2 by the probe 52, and reacts the reagent. Pour into reaction vessel 32 in part 3.
  • the predetermined position of the reagent storage unit 2 is not clearly shown in the figure, but is the case of the reagent storage unit 2. It is the position of the opening hole provided in the upper surface.
  • the position of the opening of the reagent container 22 coincides with the opening hole of the case of the reagent storage unit 2 in a state where the rotation of the table 21 of the reagent storage unit 2 is stopped. Therefore, when the tip of the arm 51 moves to a predetermined position in the reagent storage 2, the probe 52 is located at the opening of the reagent container 22 through the opening hole of the case of the reagent storage 2, and the probe 52 The reagent can be aspirated from the reagent container 22.
  • the predetermined position of the reaction unit 3 is a position of an opening provided in the upper surface of the case of the reaction unit 3 although not clearly shown in the drawing.
  • the position of the opening of the reaction vessel 32 coincides with the opening hole of the case of the reaction unit 3 in a state where the rotation of the container holding unit 31 of the reaction unit 3 is stopped. Therefore, when the tip of the arm 51 moves to a predetermined position of the reaction unit 3, the probe 52 is located at the opening of the reaction vessel 32 through the opening hole of the case of the reaction unit 3. Reagent can be injected into reaction vessel 32.
  • another predetermined position where the probe 52 is moved by the reagent dispensing unit 5 is a washing position.
  • a cleaning unit that sucks and discharges the cleaning liquid is provided at this cleaning position to clean the probe 52.
  • a sample dispensing unit 6 is provided between the reaction unit 3 and a sample supply unit 4 (sample transport unit 44) described later.
  • the sample dispensing unit 6 includes an arm 61 and a probe 62.
  • the arm 61 has a base end portion attached to the upper end of a central shaft 61a erected in the vertical direction and extends in the horizontal direction.
  • the arm 61 rotates around the central axis 61 a by the rotation of the central axis 6 la by the drive of the driving means 63.
  • the end of the arm 61 moves to a predetermined position of the reaction unit 3 or a predetermined position of the sample transport unit 44 by rotation.
  • the arm 61 moves in the vertical direction by the vertical movement of the central shaft 61a driven by the driving means 63.
  • the probe 62 dispenses a specimen, and is attached to the tip end portion of the arm 61 with the tip directed downward. That is, the sample dispensing unit 6 moves the probe 62 by moving the position of the tip of the arm 61 and moving up and down, and aspirates the sample from the sample container (for example, a blood collection tube) 42 in the sample transport unit 44 by the probe 62. Then, the sample is injected into the reaction container 32 of the reaction unit 3.
  • the sample container for example, a blood collection tube
  • the predetermined position of the sample transport unit 44 is not clearly shown in the figure, but the transport of the sample rack 41 in the sample transport unit 44 is stopped in the state where the predetermined sample container 42 in the sample rack 41 is stopped.
  • the position of the opening. Therefore, the tip of the arm 61 is at a predetermined position of the sample supply unit 4.
  • the probe 62 is moved to the position, the probe 62 is located at the opening of the predetermined sample container 42, and the sample can be aspirated from the sample container 42 by the probe 62.
  • the predetermined position of the reaction unit 3 is the same as described above, and when the tip of the arm 61 moves to the predetermined position of the reaction unit 3, the reaction vessel 3 passes through the opening of the case of the reaction unit 3.
  • a probe 62 is provided at the position of the opening, and the sample can be injected into the reaction container 32 by the probe 62. Further, another predetermined position where the probe 62 is moved by the specimen dispensing unit 6 is a washing position. Although not clearly shown in the drawing, a cleaning unit that sucks and discharges the cleaning liquid is provided at this cleaning position to clean the probe 62.
  • the automatic analyzer 1 includes a sample supply unit 4 that sequentially supplies a sample rack 41 on which a sample container 42 is mounted to each analyzer 1A to LC. For example, ten sample containers 42 can be mounted on the sample rack 41, and a bar code label (not shown) for identifying the sample rack is attached to the side of the sample rack 41. This barcode label indicates whether the sample rack 41 is an emergency sample rack with an emergency sample that requires an urgent test or a normal test sample rack with a normal sample to be tested normally. Information about the sample is displayed.
  • the sample supply unit 4 includes a sample placement unit 43, a sample transport unit 44, and a sample collection unit 45.
  • the sample placement unit 43 is also used for transporting the placed sample rack 41 to the sample transport unit 44, for example, by a belt conveyor having a plurality of L-shaped attachments 43a orthogonal to the transport direction. is there.
  • the analyzers 1A to 1C arranged in parallel are arranged at one end in the juxtaposition direction (one end on the analyzer 1A side).
  • the sample placement unit 43 places a plurality of sample racks 41 and sends the sample racks 41 one by one to the sample transport unit 44. In addition, it receives the sample rack 41 returned from the sample transport unit 44 after it is determined that a retest is necessary after the test is completed.
  • the sample transport unit 44 is a main lane serving as a transport lane provided corresponding to each analyzer 1A to LC.
  • the sample transport unit 44 is composed of, for example, a belt conveyor 44a continuously arranged along the juxtaposed direction of the analyzers 1A to 1C, and the sample rack 41 placed on the belt conveyor 44a is connected to the analyzers 1A to 1A.
  • Transport in the direction of LC The sample rack 41 is placed on the sample transport unit 44 in a state where a plurality of sample containers 42 are arranged in the transport direction.
  • This sample transport unit 44 is configured by two rows of belt conveyors 44a to form a transport line.
  • the sample rack 41 is received from the sample placement unit 43 and sent to each analyzer 1A :: sent to the LC and stored in the sample collection unit 45, and the other sample rack 41 needs to be retested from the sample collection unit 45 to the sample placement unit. Return to 43.
  • the sample collection unit 45 also has a force such as a belt conveyor provided with a plurality of L-shaped attachments 45a orthogonal to the conveyance direction, and collects the loaded sample rack 41 from one sample conveyance unit 44. In addition, among the collected sample racks 41, the racks that are determined to need reexamination are transported to the other sample transport unit 44. In this embodiment, a plurality of analyzers 1A to 1 are arranged at one end (one end on the analyzer 1C side) in the direction in which LCs are arranged in parallel. The sample collection unit 45 collects the sample rack 41 that has been dispensed by the sample dispensing unit 6. In this process, the sample rack that is determined to require re-examination as an analysis result is sent back to the sample mounting unit 43 via the sample transport unit 44.
  • a force such as a belt conveyor provided with a plurality of L-shaped attachments 45a orthogonal to the conveyance direction, and collects the loaded sample rack 41 from one sample conveyance unit 44.
  • the sample supply unit 4 has a lane shift unit 46 and a lane drive unit 47.
  • the lane shift unit 46 is provided in the middle of the sample transport unit 44, and is used for shifting the lane.
  • the lane shift unit 46 is combined with the sample transport unit 44 to form a transport line for the sample rack 41.
  • a plurality of lane shift units 46 are provided at the dispensing position in the sample dispensing unit 6 on this conveyance line and on other conveyance lines, and are conveyed by the sample conveyance unit 44.
  • the sample rack 41 also has the function of retracting the transport line upward force in the analyzer 1A-: LC direction. As shown in FIGS.
  • the lane shift unit 46 is disposed in the middle of the sample transport unit 44, for example, and has a bridge lane 46a having three belt conveyor forces that can rotate in the left-right direction in the figure. And a partition plate 46b for cutting between the bridge lanes 46a and the outside of the bridge lanes 46a.
  • the bridge lane 46a is, for example, slightly shorter than the sample rack 41, that is, transported.
  • the sample transport section is arranged on the left and right sides of the bridge lane 46a.
  • the length of both ends of the belt conveyor 44a is 44 (see Fig. 4).
  • the sample rack 41 can be transported onto the bridge lane 46a and stopped.
  • the lane shift unit 46 is connected to the analyzer side and the central bridge.
  • the partition plate 46b is for preventing the sample rack 41 from falling down, and is configured to be longer than the bridging lane 46a, for example, slightly longer than the sample rack 41, along the transport direction of the sample rack 41. Standing up.
  • the lane driving unit 47 includes driving means and guides such as an air cylinder, a solenoid, and a rack opinion, for example, and the lane shift unit 46 is directed inward or outward of the analyzer indicated by arrows A and B in FIG. It is moved and the bridge lane 46a is shifted. Therefore, in the initial state described above, the sample rack 41 is transported to the position of the bridging lane 46a and stopped, and the lane shift unit 46 is moved from the position indicated by the solid line in FIG. When moving inside the dotted analyzer, the bridge lane 46a on the center and outside of the analyzer is driven in combination with the sample transport unit 44.
  • driving means and guides such as an air cylinder, a solenoid, and a rack opinion, for example
  • the sample rack 41 located in the bridging lane 46a inside the analyzer can also retract the force on the transport line into the analyzer.
  • the analyzer-side and central bridge lane 46a is moved to the sample transport unit.
  • the sample rack 41 which is driven in combination with 44 and located in the bridging lane 46a inside the analyzer, returns to the transport line and can be transported on this transport line.
  • the sample supply unit 4 includes a barcode reader 48 and a rack position / presence / absence detector 49.
  • the barcode reader 48 is disposed on the front side in the transport direction of the sample transport unit 44, and can acquire information on the sample rack 41 transported to the sample supply position.
  • the information of the sample rack 41 is information for identifying whether the sample rack is an emergency sample rack or a normal test sample rack as described above.
  • a plurality of rack position / presence detectors 49 are arranged at predetermined positions on the analyzer side of the sample transport unit 44, and detect the position of each sample rack 41 transported by the sample transport unit 44. In addition, the presence or absence of a sample rack on the transport line is detected.
  • the rack position / presence / absence detection unit 49 is disposed in the vicinity of the lane shift unit 46, and the lane shift unit The sample rack 41 transported to 46 can be detected.
  • FIG. 5 is a block diagram showing a control system of the automatic analyzer.
  • the control system of the automatic analyzer is composed of each analyzer 1A: LC control system, sample supply unit 4 control system, and data processing unit 7 control system.
  • various information of the reagent container 22 read by a bar code reader (not shown) provided in the reagent storage unit 2 (2A, 2B) is stored in a memory (not shown) in the analysis control unit 11. .
  • the reagent remaining amount detection unit 12 connected to the analysis control unit 11 detects the reagent remaining amount in each reagent container 22 held in the reagent storage unit 2.
  • the reagent remaining amount can be detected by, for example, comparing various information in the reagent container 22 with the past reagent usage amount and calculating the current reagent remaining amount.
  • the sample placement unit 43, the sample transport unit 44, the sample collection unit 45, the lane shift unit 46, the lane drive unit 47, the barcode reader 48, the rack position and presence detection unit 49 is connected to the transfer control unit 40, and each unit is centrally controlled by the transfer control unit 40. That is, the transfer control unit 40 controls the sample racks in the sample placement unit 43, the sample transport unit 44, and the sample collection unit 45, so that the sample placement unit 43 transfers the sample racks 41 one by one to the sample transport unit 44.
  • the sample transport unit 44 controls the sample rack 41 to transport the sample rack 41 to the dispensing position of the corresponding analyzer 1A to 1C, and transfers it to the sample collection unit 45 after dispensing the sample.
  • the sample collection unit 45 performs control to collect the sample rack 41 from the sample transport unit 44.
  • the transfer control unit 40 controls to transfer the collected sample racks 41 one by one to the sample transport unit 44, and controls the sample transport unit 44 to transport the sample rack 41 to the sample placement unit 43.
  • the sample placement unit 43 controls to receive the sample rack 41 from the sample transport unit 44.
  • the transfer control unit 40 drives and controls the lane drive unit 47 so that the lane shift unit 46 can be shifted in a direction orthogonal to the transport direction of the sample rack 41.
  • the transfer control unit 40 when the sample rack 41 exists in the transfer lane bridging lane 46a and transports an emergency rack holding a sample requiring urgent analysis to the transfer line, The sample rack 41 in lane 46a is also evacuated from the transport line, and the central bridge lane The lane drive unit 47 is driven and controlled so that the emergency sample rack on the transfer line can be bridged to the sample transfer unit 44 at the rear in the transfer direction by 46a.
  • the data processing unit 7 is a part that processes various data acquired by the analyzers 1A to 1C.
  • the data processing unit 7 includes an input unit 71 and an output unit 72.
  • the input unit 71 is, for example, a keyboard or a mouse, and can input various information such as the number of samples and analysis items.
  • the output unit 72 is, for example, a display panel or a printer, and can output various kinds of information such as analysis contents including analysis results and alarms.
  • the data processing unit 7 calculates the remaining amount of the reagent of the entire automatic analyzer based on the remaining amount of the reagent detected by each analyzer 1A to LC, and outputs the calculation result from the output unit 72. Can do.
  • the lane shift unit 46 is set at the initial position indicated by the solid line in FIG.
  • the sample rack 41 is supplied from the sample placement unit 43 to the sample transport unit 44 under the control of the transfer control unit 40 (step Sl 1).
  • the barcode reader 48 reads the barcode of the sample rack 41 (step S12), and the sample transport unit 44 identifies the sample rack at the input unit 71 of the data processing unit 7 according to the barcode information. (Step S13)
  • the transfer control unit 40 determines whether the sample rack 41 that has read the barcode is an emergency sample rack or a normal test sample rack (step S 14).
  • the rack position and presence detection unit 49 detects the position and presence of the sample rack 41 (step S16). Stopping on the specific analyzer's aspiration position, that is, on the lane 46a for bridging the lane shift unit 46 in the initial state (Step S17), and dispensing the sample mounted on the sample rack 41 by the sample dispensing unit 6 Enable.
  • Step S18 Yes
  • the sample rack 41 is transported to the transport line and is collected by the sample recovery unit 45 (Step S19).
  • step S14 when the sample rack 41 that has read the barcode is an emergency sample rack (step S14: Yes), the rack position and presence detection unit 49 detects the position and presence of the sample rack 41. (Step S20), another sample rack is placed on the lane of the transport line. Judgment is made (step S21). Since the rack position / presence / absence detection unit 49 is provided in the vicinity of the lane shift unit 46, the presence of the sample rack 41 in the lane shift unit 46 can also be determined here.
  • step S21: No when there is no other sample rack on the lane of the transport line (step S21: No), the transfer control unit 40 moves the emergency sample rack to the specific analyzer's arch I in step S17. Stop at the position and enable the dispensing operation by the sample dispensing unit 6. If there is another sample rack on the lane of the transport line (step S21: Yes), this other sample rack is stopped on the bridging lane 46a of the nearby lane shift unit 46 (step S22). Then, the lane shift unit 46 is shifted to the position (dotted line in FIG. 4) where the positional force in the initial state (solid line in FIG. 4) is also shifted to the inside of the analyzer (step S23).
  • the sample rack can be retracted into the analyzer, and the lane 46a for bridging the center and outside of the analyzer can be driven in combination with the sample transport unit 44.
  • the emergency sample rack is stopped on the suction position of a specific analyzer, that is, on the bridge lane 46a of the lane shift unit 46 (Step S24), and the emergency sample rack by the sample dispensing unit 6 is stopped. Enables dispensing of the sample mounted on the.
  • the emergency sample rack is bridged to the sample transport unit 44 at the rear in the transport direction, transported to the transport line, and further to the sample recovery unit 45. Collect (step S2 6).
  • the transfer control unit 40 shifts all the lane shift units 46 on the transport line to the initial state (step S27), transports them to the transport line of the sample rack (step S28), and transports them.
  • the rack position / presence / absence detection unit 49 detects the position and presence / absence of the sample rack (step S16), thereby enabling the dispensing and transport of the sample in a specific analyzer.
  • the lane driving unit is controlled so that the sample rack retreated by the lane shift unit is shifted and quickly returned to the transport line, so that the sample rack is immediately specified from the retreated position. It can be transported to the analyzer's suction position, and the sample rack can be transported efficiently even for sample racks other than the emergency sample rack.
  • the present invention in which the sample transport unit (main lane) is configured by two lanes is not limited to this, and may be one or three or more. Further, in the embodiment, the number of bridging lanes is one more than the number of main lanes, and the power is composed of three. The present invention is not limited to this, and the lane has two or more bridging lanes than the number of main lanes. It is also possible to have a configuration with a shift unit. In this case, the number of sample racks that can be evacuated at a time by the lane shift unit increases, and the rack can be transported more efficiently.
  • the present invention is useful for an automatic analyzer that transports a sample rack holding a sample to a suction position of each analyzer via a main lane, and particularly has a high analysis priority. This is suitable for the case where the subsequent emergency sample rack is first transported.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Analytical Chemistry (AREA)
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  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

La présente invention concerne un analyseur automatique (1) qui possède plus de voies qu'une section de transport d'analyte (44), ainsi qu'une section de décalage de voie (46) ayant une voie de liaison (46a) pour décaler une armoire d'analyte dans une direction perpendiculaire à la direction du transport. Pour transporter d'abord une armoire d'analyte d'urgence suivante ayant une priorité supérieure d'analyse, une armoire d'analyte précédente (41) présente sur la voie de liaison (46a) est temporairement évacuée, d'une voie de transport par une opération de décalage de la section de décalage de voie (46) pour permettre à l'armoire d'analyte d'urgence suivante d'être transportée en premier.
PCT/JP2007/061188 2006-06-01 2007-06-01 Analyseur automatique WO2007139212A1 (fr)

Applications Claiming Priority (2)

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JP2006-153919 2006-06-01
JP2006153919A JP2007322287A (ja) 2006-06-01 2006-06-01 自動分析装置

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WO2007139212A1 true WO2007139212A1 (fr) 2007-12-06

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JP (1) JP2007322287A (fr)
WO (1) WO2007139212A1 (fr)

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CN102027375A (zh) * 2008-07-16 2011-04-20 英派克埃彼有限公司 在自动化设施中管理紧急样本的方法
EP2199805A3 (fr) * 2008-11-18 2011-06-08 BST-Bio Sensor Technology GmbH Dispositif d'analyse, support d'échantillon et unité d'analyse pour l'analyse d'échantillons
US20160124010A1 (en) * 2013-06-17 2016-05-05 Hitachi High-Technologies Corporation Automatic analyzer
JP2017173156A (ja) * 2016-03-24 2017-09-28 株式会社日立ハイテクノロジーズ 検体搬送システムおよび検体検査システム
EP2693220A3 (fr) * 2012-07-31 2018-01-03 Sysmex Corporation Trieuse de tube, système de traitement d'échantillon et procédé de transport d'échantillon
EP2711715A3 (fr) * 2012-09-20 2018-01-17 Sysmex Corporation Appareil et procédé de tri d'échantillons

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CN102292645B (zh) * 2009-01-27 2014-02-12 株式会社日立高新技术 自动分析装置及自动分析方法
PL396829A1 (pl) 2011-10-31 2013-05-13 Pz Cormay Spólka Akcyjna Sposób przemieszczania próbki w analizatorze biochemicznym i analizator biochemiczny realizujacy ten sposób
JP5984699B2 (ja) * 2013-01-31 2016-09-06 シスメックス株式会社 検体移し替え装置、検体移し替えシステム、検体移し替え方法および搬送装置
CN103983797B (zh) 2013-01-31 2018-05-04 希森美康株式会社 容器分类装置、样本处理***及容器分类方法
JP6468973B2 (ja) * 2015-08-27 2019-02-13 株式会社日立ハイテクノロジーズ 検体搬送システム
CN107290557B (zh) * 2017-06-30 2019-06-04 迈克医疗电子有限公司 样本分析检测单元及样本分析仪

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* Cited by examiner, † Cited by third party
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CN102027375A (zh) * 2008-07-16 2011-04-20 英派克埃彼有限公司 在自动化设施中管理紧急样本的方法
EP2199805A3 (fr) * 2008-11-18 2011-06-08 BST-Bio Sensor Technology GmbH Dispositif d'analyse, support d'échantillon et unité d'analyse pour l'analyse d'échantillons
EP2693220A3 (fr) * 2012-07-31 2018-01-03 Sysmex Corporation Trieuse de tube, système de traitement d'échantillon et procédé de transport d'échantillon
EP2711715A3 (fr) * 2012-09-20 2018-01-17 Sysmex Corporation Appareil et procédé de tri d'échantillons
US10001498B2 (en) 2012-09-20 2018-06-19 Sysmex Corporation Sample sorting apparatus, sample processing system, and sample sorting method
US20160124010A1 (en) * 2013-06-17 2016-05-05 Hitachi High-Technologies Corporation Automatic analyzer
EP3012635A4 (fr) * 2013-06-17 2017-03-22 Hitachi High-Technologies Corporation Dispositif d'analyse automatique
US9709588B2 (en) * 2013-06-17 2017-07-18 Hitachi High-Technologies Corporation Automatic analyzer
US10495658B2 (en) 2013-06-17 2019-12-03 Hitachi High-Technologies Corporation Automatic analyzer
EP3654040A1 (fr) * 2013-06-17 2020-05-20 Hitachi High-Technologies Corporation Procédé de transport d'échantillon et analyseur automatique adapté pour réaliser le procédé
US11199559B2 (en) 2013-06-17 2021-12-14 Hitachi High-Tech Corporation Automatic analyzer
JP2017173156A (ja) * 2016-03-24 2017-09-28 株式会社日立ハイテクノロジーズ 検体搬送システムおよび検体検査システム

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