WO2007095523A3 - Stable dosage formulations of imidazolylalkyl-pyridines - Google Patents

Stable dosage formulations of imidazolylalkyl-pyridines Download PDF

Info

Publication number
WO2007095523A3
WO2007095523A3 PCT/US2007/062034 US2007062034W WO2007095523A3 WO 2007095523 A3 WO2007095523 A3 WO 2007095523A3 US 2007062034 W US2007062034 W US 2007062034W WO 2007095523 A3 WO2007095523 A3 WO 2007095523A3
Authority
WO
WIPO (PCT)
Prior art keywords
imidazolylalkyl
pyridines
dosage formulations
stable dosage
stable
Prior art date
Application number
PCT/US2007/062034
Other languages
French (fr)
Other versions
WO2007095523A2 (en
Inventor
Christian N Lavedan
Deepak Phadke
Original Assignee
Vanda Pharmaceuticals Inc
Christian N Lavedan
Deepak Phadke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vanda Pharmaceuticals Inc, Christian N Lavedan, Deepak Phadke filed Critical Vanda Pharmaceuticals Inc
Priority to EP07756903A priority Critical patent/EP1986659A4/en
Priority to BRPI0707736-0A priority patent/BRPI0707736A2/en
Priority to CA002642275A priority patent/CA2642275A1/en
Priority to JP2008554542A priority patent/JP5044572B2/en
Priority to AU2007214487A priority patent/AU2007214487A1/en
Priority to US12/278,298 priority patent/US8865210B2/en
Priority to MX2008010322A priority patent/MX2008010322A/en
Publication of WO2007095523A2 publication Critical patent/WO2007095523A2/en
Priority to NO20083646A priority patent/NO20083646L/en
Publication of WO2007095523A3 publication Critical patent/WO2007095523A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Stable formulations of imidazolylalkyl-pyridines, including controlled-release formulations.
PCT/US2007/062034 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines WO2007095523A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP07756903A EP1986659A4 (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines
BRPI0707736-0A BRPI0707736A2 (en) 2006-02-13 2007-02-13 stable dosage imidazolylalkyl pyridines formulations
CA002642275A CA2642275A1 (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines
JP2008554542A JP5044572B2 (en) 2006-02-13 2007-02-13 Stable dosage formulation of imidazolylalkyl-pyridine
AU2007214487A AU2007214487A1 (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines
US12/278,298 US8865210B2 (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines
MX2008010322A MX2008010322A (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines.
NO20083646A NO20083646L (en) 2006-02-13 2008-08-25 Stable dosage formulations of imidazolylalkyl pyridines

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US77272706P 2006-02-13 2006-02-13
US60/772,727 2006-02-13

Publications (2)

Publication Number Publication Date
WO2007095523A2 WO2007095523A2 (en) 2007-08-23
WO2007095523A3 true WO2007095523A3 (en) 2008-11-27

Family

ID=38372210

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2007/062034 WO2007095523A2 (en) 2006-02-13 2007-02-13 Stable dosage formulations of imidazolylalkyl-pyridines

Country Status (12)

Country Link
US (1) US8865210B2 (en)
EP (1) EP1986659A4 (en)
JP (1) JP5044572B2 (en)
KR (1) KR20080095873A (en)
CN (1) CN101394849A (en)
AU (1) AU2007214487A1 (en)
BR (1) BRPI0707736A2 (en)
CA (1) CA2642275A1 (en)
MX (1) MX2008010322A (en)
NO (1) NO20083646L (en)
WO (1) WO2007095523A2 (en)
ZA (1) ZA200806439B (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083978A (en) * 1976-01-27 1978-04-11 Egyt Gyogyszervegyeszeti Gyar Oxime ethers
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
US20050244496A1 (en) * 1999-08-26 2005-11-03 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4131584A1 (en) * 1991-09-23 1993-03-25 Sandoz Ag IMIDAZOLYLMETHYL-PYRIDINE, THEIR PRODUCTION AND USE AS A PHARMACEUTICAL
US20050244497A1 (en) 1997-11-05 2005-11-03 Wockhardt Limited Delayed delivery system for acid-sensitive drugs
US6312728B1 (en) 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
US5968554A (en) * 1998-07-07 1999-10-19 Cascade Development, Inc. A Subsidiary Of Cardinal Health, Inc. Sustained release pharmaceutical preparation
US6627223B2 (en) 2000-02-11 2003-09-30 Eurand Pharmaceuticals Ltd. Timed pulsatile drug delivery systems
JP2001302635A (en) 2000-04-21 2001-10-31 Suntory Ltd New heterocyclic compound
US6979462B1 (en) 2000-10-03 2005-12-27 Mutual Pharmaceutical Co., Inc. Stabilization of solid drug formulations
US6569311B2 (en) 2001-02-02 2003-05-27 Clariant Finance (Bvi) Limited Continuous electrochemical process for preparation of zinc powder
US6500454B1 (en) 2001-10-04 2002-12-31 Eurand Pharmaceuticals Ltd. Timed, sustained release systems for propranolol
US6663888B2 (en) 2001-12-14 2003-12-16 Eurand Pharmaceuticals Ltd. Pulsatile release histamine H2 antagonist dosage form
AR046410A1 (en) 2003-09-18 2005-12-07 Cephalon Inc PHARMACEUTICAL COMPOSITIONS FOR MODIFIED LIBERATION OF MODAFINILO
JP2005194491A (en) 2003-12-09 2005-07-21 Mitsubishi Plastics Ind Ltd Resin composition and resin film using thereof
KR101187461B1 (en) 2005-07-29 2012-10-02 반다 파마슈티칼즈, 인코퍼레이티드. Method of improving wakefulness

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4083978A (en) * 1976-01-27 1978-04-11 Egyt Gyogyszervegyeszeti Gyar Oxime ethers
US5635521A (en) * 1991-09-23 1997-06-03 Sandoz Ltd. Imidazolylmethyl-pyridines
US20050244496A1 (en) * 1999-08-26 2005-11-03 Neurocrine Biosciences, Inc. Controlled-release sedative-hypnotic compositions and methods related thereto

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1986659A4 *

Also Published As

Publication number Publication date
JP2009526783A (en) 2009-07-23
CA2642275A1 (en) 2007-08-23
EP1986659A4 (en) 2009-10-21
MX2008010322A (en) 2009-03-05
KR20080095873A (en) 2008-10-29
BRPI0707736A2 (en) 2011-05-10
JP5044572B2 (en) 2012-10-10
CN101394849A (en) 2009-03-25
NO20083646L (en) 2008-08-25
US8865210B2 (en) 2014-10-21
WO2007095523A2 (en) 2007-08-23
EP1986659A2 (en) 2008-11-05
ZA200806439B (en) 2009-10-28
AU2007214487A1 (en) 2007-08-23
US20090011011A1 (en) 2009-01-08

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