WO2007059350A3 - Preparation of alkoxyamines - Google Patents

Preparation of alkoxyamines Download PDF

Info

Publication number
WO2007059350A3
WO2007059350A3 PCT/US2006/044931 US2006044931W WO2007059350A3 WO 2007059350 A3 WO2007059350 A3 WO 2007059350A3 US 2006044931 W US2006044931 W US 2006044931W WO 2007059350 A3 WO2007059350 A3 WO 2007059350A3
Authority
WO
WIPO (PCT)
Prior art keywords
reducing agent
nitroxide
coupling process
coupling
transition metal
Prior art date
Application number
PCT/US2006/044931
Other languages
French (fr)
Other versions
WO2007059350A2 (en
Inventor
Krzysztof Matyjaszewski
James Spanswick
Original Assignee
Univ Carnegie Mellon
Krzysztof Matyjaszewski
James Spanswick
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Carnegie Mellon, Krzysztof Matyjaszewski, James Spanswick filed Critical Univ Carnegie Mellon
Publication of WO2007059350A2 publication Critical patent/WO2007059350A2/en
Publication of WO2007059350A3 publication Critical patent/WO2007059350A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C239/00—Compounds containing nitrogen-to-halogen bonds; Hydroxylamino compounds or ethers or esters thereof
    • C07C239/08—Hydroxylamino compounds or their ethers or esters
    • C07C239/20—Hydroxylamino compounds or their ethers or esters having oxygen atoms of hydroxylamino groups etherified

Abstract

Embodiments of the process for the preparation of alkoxyamines of the present invention are directed to conducting a coupling reaction in a reaction medium initially comprising at least one transition metal catalyst, an ATRP initiator and a nitroxide or nitroxide precursor. The reaction medium may additionally comprise a reducing agent. In certain embodiments the reducing agent is the nitroxide precursor. The reducing agent may be added initially or during the coupling process in a continuous or intermittent manner. The coupling process may further comprises reacting the reducing agent with at least one of the transition metal catalyst in an oxidized state further comprising a radically transferable atom or group to form a compound that does not participate significantly in control of the coupling process. Embodiments of the present invention comprise reacting a reducing agent with at least one of catalyst in an oxidized state and an ATRP initiator to initiate and/or maintain catalytic activity throughout the coupling process between the formed radical and added nitroxide.
PCT/US2006/044931 2005-11-17 2006-11-17 Preparation of alkoxyamines WO2007059350A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US73754505P 2005-11-17 2005-11-17
US60/737,545 2005-11-17

Publications (2)

Publication Number Publication Date
WO2007059350A2 WO2007059350A2 (en) 2007-05-24
WO2007059350A3 true WO2007059350A3 (en) 2007-07-26

Family

ID=38038559

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/044931 WO2007059350A2 (en) 2005-11-17 2006-11-17 Preparation of alkoxyamines

Country Status (1)

Country Link
WO (1) WO2007059350A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7795355B2 (en) 2004-03-05 2010-09-14 Carnegie Mellon University Preparation of functional polymers
JP5171248B2 (en) 2004-03-05 2013-03-27 カーネギー−メロン ユニバーシティ Atom transfer radical polymerization
WO2007025086A2 (en) 2005-08-23 2007-03-01 Carnegie Mellon University Atom transfer radical polymerization in microemulsion and true emulsion polymerization
CN101379091B (en) 2005-08-26 2012-05-30 卡内基梅隆大学 Polymerization process with catalyst reactivation
US8367051B2 (en) 2006-10-09 2013-02-05 Carnegie Mellon University Preparation of functional gel particles with a dual crosslink network
WO2009023353A1 (en) 2007-05-23 2009-02-19 Carnegie Mellon University Hybrid particle composite structures with reduced scattering
WO2008148000A1 (en) 2007-05-23 2008-12-04 Carnegie Mellon University Atom transfer dispersion polymerization
WO2012091965A1 (en) 2010-12-17 2012-07-05 Carnegie Mellon University Electrochemically mediated atom transfer radical polymerization
EP2747753B1 (en) 2011-08-22 2023-03-29 Carnegie Mellon University Atom transfer radical polymerization under biologically compatible conditions
WO2013126745A2 (en) 2012-02-23 2013-08-29 Carnegie Mellon University Ligands designed to provide highly active catalyst complexes
EP2824155A1 (en) * 2013-07-09 2015-01-14 HILTI Aktiengesellschaft Reaction resin composition and its use
US9982070B2 (en) 2015-01-12 2018-05-29 Carnegie Mellon University Aqueous ATRP in the presence of an activator regenerator
US11174325B2 (en) 2017-01-12 2021-11-16 Carnegie Mellon University Surfactant assisted formation of a catalyst complex for emulsion atom transfer radical polymerization processes

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310149B1 (en) * 1996-06-12 2001-10-30 University Of Warwick Polymerization catalyst and process
US6541580B1 (en) * 1995-03-31 2003-04-01 Carnegie Mellon University Atom or group transfer radical polymerization
US6569967B1 (en) * 1999-02-18 2003-05-27 Atofina Alkoxyamines derived from β-phosphorous nitroxides

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6541580B1 (en) * 1995-03-31 2003-04-01 Carnegie Mellon University Atom or group transfer radical polymerization
US6310149B1 (en) * 1996-06-12 2001-10-30 University Of Warwick Polymerization catalyst and process
US6569967B1 (en) * 1999-02-18 2003-05-27 Atofina Alkoxyamines derived from β-phosphorous nitroxides

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JOHAN P. A. HEUTS ET AL.: "ATOM TRANSFER RADICAL POLYMERIZATION IN THE PRESENCE OF A THIOL: MORE EVIDENCE SUPPORTING RADICAL INTERMEDIATES", MACROMOL. CHEM. PHYS., vol. 200, no. 6, 1999, pages 1380 - 1385, XP002435319 *
KRZYSZTOF MATYJASZEWSKI ET AL: "DETERMINATION OF ACTIVATION AND DEACTIVATION RATE CONSTANTS OF MODEL COMPOUNDS IN ATOM TRANSFER RADICAL POLYMERIZATION", MACROMOLECULES, vol. 34, 2001, pages 5125 - 5131, XP002435317 *
VRIES DE A ET AL: "THE EFFECT OF REDUCING MONOSACCHARIDES ON THE ATOM TRANSFER RADICAL POLYMERIZATION OF BUTYL METHACRYLATE", MACROMOLECULAR CHEMISTRY AND PHYSICS, WILEY-VCH VERLAG, WEINHEIM, DE, vol. 202, no. 9, 6 July 2001 (2001-07-06), pages 1645 - 1648, XP001068087, ISSN: 1022-1352 *
YVES GNANOU ET AL.: "EFFECT OF PHENOL AND DERIVATIVES ON ATOM TRANSFER RADICAL POLYMERIZATION IN THE PRESENCE OF AIR", JOURNAL OF POLYMER SCIENCE: PART A: POLYMER CHEMISTRY, vol. 42, 2004, pages 351 - 359, XP002435318 *

Also Published As

Publication number Publication date
WO2007059350A2 (en) 2007-05-24

Similar Documents

Publication Publication Date Title
WO2007059350A3 (en) Preparation of alkoxyamines
WO2008009940A3 (en) Control of selective catalytic reduction
WO2008030439A3 (en) Dehydrofluorination process to manufacture hydrofluoroolefins
MY142272A (en) Method for preparing a catalyst for oxidation of methanol to formaldehyde
WO2007014191A3 (en) Weld metal material apparatus and method
WO2008073297A3 (en) Three dimensional printing material system and method using peroxide cure
AU4186500A (en) Polymerization catalyst ligands, catalytic metal complexes and compositions and processes using and methods of making same
AU5396000A (en) Plate-like multi-metal cyanide compounds, methods for their use and their use inthe production of polyethererpolyols
WO2004052939A3 (en) Ligands for metals and improved metal-catalyzed processes based thereon
WO2002079468A8 (en) A method of increasing complementarity in a heteroduplex polynucleotide
WO2003020988A1 (en) Production method of metal iron
WO2010077537A3 (en) Fluid catalytic cracking system and process
IN2006CH00411A (en)
JP2008511536A5 (en)
EP1764288A3 (en) Vehicle body
AU2001273986A1 (en) Method for the selective production of acetic acid by catalytic oxidation of ethane and/or ethylene
EP1579910A3 (en) Catalyst for production of acrylic acid and process for production of acrylic acid using the catalyst
WO2007008997A3 (en) Template specific inhibition of pcr
WO2003014109A1 (en) Process for producing pyridine compound
MXPA03005516A (en) Alkane oxidation catalyst, process for producing the same, and process for producing oxygen-containing unsaturated compound.
AU2002221508A1 (en) An oxidation reaction process catalysized by phase-transfer catalyst controlling reaction
WO2001085805A3 (en) Highly functionalized polymers and a process for making the same
WO2008034644A3 (en) Process for making anastrozole
WO2005047462A3 (en) Universal control for nucleic acid amplification
EP1178026A4 (en) Processes for producing oxide with higher oxidation than alcohol

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 06838089

Country of ref document: EP

Kind code of ref document: A2

122 Ep: pct application non-entry in european phase

Ref document number: 06838089

Country of ref document: EP

Kind code of ref document: A2