WO2007038564A3 - Global transcription machinery engineering - Google Patents
Global transcription machinery engineering Download PDFInfo
- Publication number
- WO2007038564A3 WO2007038564A3 PCT/US2006/037597 US2006037597W WO2007038564A3 WO 2007038564 A3 WO2007038564 A3 WO 2007038564A3 US 2006037597 W US2006037597 W US 2006037597W WO 2007038564 A3 WO2007038564 A3 WO 2007038564A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- transcription machinery
- machinery engineering
- global transcription
- global
- engineering
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/24—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
- C07K14/245—Escherichia (G)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1058—Directional evolution of libraries, e.g. evolution of libraries is achieved by mutagenesis and screening or selection of mixed population of organisms
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
- C12N15/1034—Isolating an individual clone by screening libraries
- C12N15/1079—Screening libraries by altering the phenotype or phenotypic trait of the host
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P23/00—Preparation of compounds containing a cyclohexene ring having an unsaturated side chain containing at least ten carbon atoms bound by conjugated double bonds, e.g. carotenes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
- C12P7/04—Preparation of oxygen-containing organic compounds containing a hydroxy group acyclic
- C12P7/06—Ethanol, i.e. non-beverage
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/42—Hydroxy-carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02E—REDUCTION OF GREENHOUSE GAS [GHG] EMISSIONS, RELATED TO ENERGY GENERATION, TRANSMISSION OR DISTRIBUTION
- Y02E50/00—Technologies for the production of fuel of non-fossil origin
- Y02E50/10—Biofuels, e.g. bio-diesel
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Bioinformatics & Computational Biology (AREA)
- Ecology (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Processing Of Solid Wastes (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
Abstract
Priority Applications (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP06825155A EP1943343A2 (en) | 2005-09-28 | 2006-09-28 | Global transcription machinery engineering |
JP2008533553A JP2009509533A (en) | 2005-09-28 | 2006-09-28 | Comprehensive transcription mechanism engineering |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11/238,096 US20070072194A1 (en) | 2005-09-28 | 2005-09-28 | Global transcription machinery engineering |
US11/238,096 | 2005-09-28 | ||
US74831505P | 2005-12-07 | 2005-12-07 | |
US60/748,315 | 2005-12-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007038564A2 WO2007038564A2 (en) | 2007-04-05 |
WO2007038564A3 true WO2007038564A3 (en) | 2007-06-28 |
Family
ID=37891512
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/037597 WO2007038564A2 (en) | 2005-09-28 | 2006-09-28 | Global transcription machinery engineering |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1943343A2 (en) |
JP (1) | JP2009509533A (en) |
WO (1) | WO2007038564A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2407541A1 (en) * | 2006-12-07 | 2012-01-18 | Massachusetts Institute of Technology | Global transcription machinery engineering |
US8193314B2 (en) | 2007-07-12 | 2012-06-05 | Massachusetts Institute Of Technology | Transcriptional engineering of Lactobacillus |
US9267118B2 (en) | 2007-08-17 | 2016-02-23 | Massachusetts Institute Of Technology | Methods for identifying bacterial strains that produce L-tyrosine |
US20100330614A1 (en) * | 2007-11-06 | 2010-12-30 | Massachusetts Institute Of Technology | Global transcription machinery engineering targeting the rnap alpha subunit (rpoa) |
WO2011159629A2 (en) * | 2010-06-14 | 2011-12-22 | Cobalt Technologies, Inc. | Salt selection of microbial mutants to increase bioproduct tolerance, titer, or osmotic shock tolerance |
KR101646310B1 (en) * | 2013-06-24 | 2016-08-12 | 씨제이제일제당 (주) | Microorganisms for production of l-threonine and process for producing l-threonine using the same |
CN104630149B (en) * | 2013-11-08 | 2018-08-21 | 中国科学院广州生物医药与健康研究院 | Xenogenic mitochondrial imported into the method in mammalian cell |
CN104845924B (en) * | 2015-04-01 | 2018-03-16 | 农业部沼气科学研究所 | Zymomonas mobilis of one plant of resistance to furtural and its preparation method and application |
-
2006
- 2006-09-28 EP EP06825155A patent/EP1943343A2/en not_active Withdrawn
- 2006-09-28 WO PCT/US2006/037597 patent/WO2007038564A2/en active Application Filing
- 2006-09-28 JP JP2008533553A patent/JP2009509533A/en active Pending
Non-Patent Citations (9)
Title |
---|
ALPER H. AND STEPHANOPOULOS G.: "Global transcription machinery enginering: a new approach for improving cellular phenotype", METABOLIC ENGINEERING, 8 January 2007 (2007-01-08), XP002428724 * |
ALPER H.: "Development of systematic and combinatorial approaches for the metabolic engineering of microorganisms", June 2006, MASSACHUSSET INSTITUTE OF TECHNOLOGY, BOSTON, USA, XP002429707 * |
ALPER HAL ET AL: "Engineering yeast transcription machinery for improved ethanol tolerance and production.", SCIENCE (NEW YORK, N.Y.) 8 DEC 2006, vol. 314, no. 5805, 8 December 2006 (2006-12-08), pages 1565 - 1568, XP002428725, ISSN: 1095-9203 * |
ALPER HAL ET AL: "Tuning genetic control through promoter engineering.", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 6 SEP 2005, vol. 102, no. 36, 6 September 2005 (2005-09-06), pages 12678 - 12683, XP002428722, ISSN: 0027-8424 * |
GOWRISHANKAR J ET AL: "In vitro properties of RpoS (sigma(S)) mutants of Escherichia coli with postulated N-terminal subregion 1.1 or C-terminal region 4 deleted.", JOURNAL OF BACTERIOLOGY APR 2003, vol. 185, no. 8, April 2003 (2003-04-01), pages 2673 - 2679, XP002430364, ISSN: 0021-9193 * |
MAHREN SUSANNE ET AL: "Functional interaction of region 4 of the extracytoplasmic function sigma factor FecI with the cytoplasmic portion of the FecR transmembrane protein of the Escherichia coli ferric citrate transport system.", JOURNAL OF BACTERIOLOGY JUL 2002, vol. 184, no. 13, July 2002 (2002-07-01), pages 3704 - 3711, XP002430363, ISSN: 0021-9193 * |
See also references of EP1943343A2 * |
WU WEI-HUA ET AL: "Mutational analysis of yeast TFIIB: A functional relationship between Ssu72 and sub1/tsp1 defined by allele-specific interactions with TFIIB", GENETICS, vol. 153, no. 2, October 1999 (1999-10-01), pages 643 - 652, XP002428723, ISSN: 0016-6731 * |
YURA T. AND OSAWA T.: ""Genetic studies of RNA polymerase sigma factor in Escherichia coli" in Genetics and Evolution of RNA Polymerase, tRNA and Ribosomes", 1980, UNIVERSITY OF TOKYO PRESS, TOKYO, JAPAN, XP001245627 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007038564A2 (en) | 2007-04-05 |
EP1943343A2 (en) | 2008-07-16 |
JP2009509533A (en) | 2009-03-12 |
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