WO2007031140A3 - Extracts from epimedium species method for production and use thereof - Google Patents

Extracts from epimedium species method for production and use thereof Download PDF

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Publication number
WO2007031140A3
WO2007031140A3 PCT/EP2006/006929 EP2006006929W WO2007031140A3 WO 2007031140 A3 WO2007031140 A3 WO 2007031140A3 EP 2006006929 W EP2006006929 W EP 2006006929W WO 2007031140 A3 WO2007031140 A3 WO 2007031140A3
Authority
WO
WIPO (PCT)
Prior art keywords
extracts
production
oestrogen
special purpose
epimedium species
Prior art date
Application number
PCT/EP2006/006929
Other languages
German (de)
French (fr)
Other versions
WO2007031140A2 (en
Inventor
Egon Koch
Clemens Erdelmeier
Hermann Hauer
Original Assignee
Schwabe Willmar Gmbh & Co
Egon Koch
Clemens Erdelmeier
Hermann Hauer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schwabe Willmar Gmbh & Co, Egon Koch, Clemens Erdelmeier, Hermann Hauer filed Critical Schwabe Willmar Gmbh & Co
Priority to EP06828796A priority Critical patent/EP1904075A2/en
Publication of WO2007031140A2 publication Critical patent/WO2007031140A2/en
Publication of WO2007031140A3 publication Critical patent/WO2007031140A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Diabetes (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to special purpose extracts (liquid and dry extracts) from Epimedium species, methods for production thereof, medicaments and foodstuffs comprising the same, in particular, dietary products and adjuncts including Medical Food and Dietary Supplements and use of the special purpose extracts for the prophylaxis and treatment of disease states caused by a lack of oestrogen or by a dysregulation of sex hormone metabolism, in particular, oestrogen metabolism.
PCT/EP2006/006929 2005-07-15 2006-07-14 Extracts from epimedium species method for production and use thereof WO2007031140A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06828796A EP1904075A2 (en) 2005-07-15 2006-07-14 Extracts from epimedium species method for production and use thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005033241 2005-07-15
DE102005033241.2 2005-07-15

Publications (2)

Publication Number Publication Date
WO2007031140A2 WO2007031140A2 (en) 2007-03-22
WO2007031140A3 true WO2007031140A3 (en) 2007-08-09

Family

ID=37865295

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/006929 WO2007031140A2 (en) 2005-07-15 2006-07-14 Extracts from epimedium species method for production and use thereof

Country Status (2)

Country Link
EP (1) EP1904075A2 (en)
WO (1) WO2007031140A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104001004A (en) * 2014-06-16 2014-08-27 徐艳 Traditional Chinese medicine composition for curing fractures and osteoporosis and preparation method and application thereof
CN105214012A (en) * 2015-11-16 2016-01-06 陈明海 A kind of Chinese medicine composition for the treatment of cyclomastopathy
CN112552356A (en) * 2020-06-29 2021-03-26 郑州福瑞堂制药有限公司 Method for preparing icariin
CN113980065A (en) * 2021-11-09 2022-01-28 陕西理工大学 Method for extracting icariin from epimedium herb

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071883A (en) * 1998-07-28 2000-06-06 Chen; Huifang Flavone analogues useful as anti-rejection agents
US20020013280A1 (en) * 2000-06-16 2002-01-31 Zhongcheng Xin Pharmaceutical composition for preventing and treating sexual dysfunction and vasculargenic disease comprising icariin
WO2002013842A1 (en) * 2000-08-15 2002-02-21 Hauser, Inc. Compositions comprising icariside i and anhydroicaritin and methods for making the same
US6476203B1 (en) * 2002-03-14 2002-11-05 Xinxian Zhao Safe pharmaceutical composition for treating and preventing infertility and increasing immune function
CN1403468A (en) * 2002-09-26 2003-03-19 中国药科大学 Prepn of epimedium general flavone with osteoporosis resisting function
US20030153515A1 (en) * 1999-06-17 2003-08-14 Zhongcheng Xin Method for prevention and treatment of male and female sexual dysfunction
US20030170292A1 (en) * 2001-11-09 2003-09-11 National University Of Singapore Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071883A (en) * 1998-07-28 2000-06-06 Chen; Huifang Flavone analogues useful as anti-rejection agents
US20030153515A1 (en) * 1999-06-17 2003-08-14 Zhongcheng Xin Method for prevention and treatment of male and female sexual dysfunction
US20020013280A1 (en) * 2000-06-16 2002-01-31 Zhongcheng Xin Pharmaceutical composition for preventing and treating sexual dysfunction and vasculargenic disease comprising icariin
WO2002013842A1 (en) * 2000-08-15 2002-02-21 Hauser, Inc. Compositions comprising icariside i and anhydroicaritin and methods for making the same
US20030170292A1 (en) * 2001-11-09 2003-09-11 National University Of Singapore Methods for preparing an estrogenic preparation and isolated estrogenic compounds from a plant and uses thereof
US6476203B1 (en) * 2002-03-14 2002-11-05 Xinxian Zhao Safe pharmaceutical composition for treating and preventing infertility and increasing immune function
CN1403468A (en) * 2002-09-26 2003-03-19 中国药科大学 Prepn of epimedium general flavone with osteoporosis resisting function

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 200354, Derwent World Patents Index; AN 2003-569805, XP002428387 *
MENG F H ET AL: "Osteoblastic proliferative activity of Epimedium brevicornum Maxim", PHYTOMEDICINE, GUSTAV FISCHER VERLAG, STUTTGART, DE, vol. 12, no. 3, 22 March 2005 (2005-03-22), pages 189 - 193, XP004957235, ISSN: 0944-7113 *
MENG FANHAO ET AL: "OSTEOBLASTIC PROLIFERATION STIMULATING ACTIVITY OF EPIMEDIUM KOREANUM NAKAI EXTRACTS AND ITS FLAVONOL GLYCOSIDES", PHARMACEUTICAL BIOLOGY, SWETS AND ZEITLINGER, LISSE,, NL, vol. 43, no. 1, January 2005 (2005-01-01), pages 92 - 95, XP009081516, ISSN: 1388-0209 *

Also Published As

Publication number Publication date
EP1904075A2 (en) 2008-04-02
WO2007031140A2 (en) 2007-03-22

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