WO2007011887A3 - Production of morphinan alkaloids and derivatives in plants - Google Patents
Production of morphinan alkaloids and derivatives in plants Download PDFInfo
- Publication number
- WO2007011887A3 WO2007011887A3 PCT/US2006/027731 US2006027731W WO2007011887A3 WO 2007011887 A3 WO2007011887 A3 WO 2007011887A3 US 2006027731 W US2006027731 W US 2006027731W WO 2007011887 A3 WO2007011887 A3 WO 2007011887A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- derivatives
- plants
- production
- morphinan alkaloids
- morphinan
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/22—Bridged ring systems
- C07D221/28—Morphinans
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
- C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
- C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/001—Oxidoreductases (1.) acting on the CH-CH group of donors (1.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1048—Glycosyltransferases (2.4)
- C12N9/1051—Hexosyltransferases (2.4.1)
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Nutrition Science (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Compositions and methods for producing alkaloid compounds, e.g., morphinan alkaloids and derivatives thereof, in plants are disclosed. For example, a plant cell expressing a morphinan alkaloid modifying enzyme that catalyzes the synthesis of one or more morphinan alkaloids or derivatives is disclosed.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70055805P | 2005-07-18 | 2005-07-18 | |
US60/700,558 | 2005-07-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2007011887A2 WO2007011887A2 (en) | 2007-01-25 |
WO2007011887A3 true WO2007011887A3 (en) | 2007-10-04 |
Family
ID=37669475
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/027731 WO2007011887A2 (en) | 2005-07-18 | 2006-07-18 | Production of morphinan alkaloids and derivatives in plants |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2007011887A2 (en) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7598367B2 (en) | 2005-06-30 | 2009-10-06 | Ceres, Inc. | Early light-induced protein promoters |
US7655786B2 (en) | 2006-03-15 | 2010-02-02 | E.I. Du Pont De Nemours And Company | Gene expression modulating element |
CN103270947B (en) * | 2013-03-08 | 2014-09-03 | 浙江省农业科学院 | Duvalia angustiloba tissue culturing method |
GB201413899D0 (en) | 2014-08-06 | 2014-09-17 | Johnson Matthey Plc | Catalyst and use therof |
CA3030446C (en) | 2016-07-18 | 2021-01-26 | Saint-Gobain Glass France | Transparent fire protection glazing having burglary-resistant and antipanic properties |
KR20190034614A (en) | 2016-08-03 | 2019-04-02 | 쌩-고벵 글래스 프랑스 | A transparent, anti-scattering, anti-bullet glazing with fire characteristics |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1270727A1 (en) * | 2001-06-11 | 2003-01-02 | Institut für Pflanzenbiochemie | Salutaridinol 7-O-acetyltransferase and derivatives thereof |
WO2005053382A1 (en) * | 2003-12-02 | 2005-06-16 | Johnson & Johnson Research Pty Limited | Modulation of cytochrome p-450 reductase activity in poppy plants |
-
2006
- 2006-07-18 WO PCT/US2006/027731 patent/WO2007011887A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1270727A1 (en) * | 2001-06-11 | 2003-01-02 | Institut für Pflanzenbiochemie | Salutaridinol 7-O-acetyltransferase and derivatives thereof |
WO2005053382A1 (en) * | 2003-12-02 | 2005-06-16 | Johnson & Johnson Research Pty Limited | Modulation of cytochrome p-450 reductase activity in poppy plants |
Non-Patent Citations (3)
Title |
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BRUCE ET AL: "Engineering pathways for transformations of morphine alkaloids", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 13, no. 6, June 1995 (1995-06-01), pages 200 - 205, XP005030343, ISSN: 0167-7799 * |
RITTER J K ET AL: "Cloning and expression of human liver UDP-glucuronosyltransferase in COS-1 cells", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 265, no. 14, 15 May 1990 (1990-05-15), pages 7900 - 7906, XP002121919, ISSN: 0021-9258 * |
WOO HO-HYUNG ET AL: "Altered life cycle in Arabidopsis plants expressing PsUGT1, a UDP-glucuronosyltransferase-encoding gene from pea.", PLANT PHYSIOLOGY (ROCKVILLE), vol. 133, no. 2, October 2003 (2003-10-01), pages 538 - 548, XP002423855, ISSN: 0032-0889 * |
Also Published As
Publication number | Publication date |
---|---|
WO2007011887A2 (en) | 2007-01-25 |
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