WO2006136892A3 - Neuartige cherlasky - fusionsproteine enthalten antikorperbindeproteine oder ihre regionen - Google Patents

Neuartige cherlasky - fusionsproteine enthalten antikorperbindeproteine oder ihre regionen Download PDF

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Publication number
WO2006136892A3
WO2006136892A3 PCT/IB2006/001490 IB2006001490W WO2006136892A3 WO 2006136892 A3 WO2006136892 A3 WO 2006136892A3 IB 2006001490 W IB2006001490 W IB 2006001490W WO 2006136892 A3 WO2006136892 A3 WO 2006136892A3
Authority
WO
WIPO (PCT)
Prior art keywords
regions
novel
antibody binding
cherkasky
containing antibody
Prior art date
Application number
PCT/IB2006/001490
Other languages
English (en)
French (fr)
Other versions
WO2006136892A2 (de
Inventor
Alexander Cherkasky
Original Assignee
Alexander Cherkasky
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200510028619 external-priority patent/DE102005028619A1/de
Priority claimed from DE200510028545 external-priority patent/DE102005028545A1/de
Application filed by Alexander Cherkasky filed Critical Alexander Cherkasky
Publication of WO2006136892A2 publication Critical patent/WO2006136892A2/de
Publication of WO2006136892A3 publication Critical patent/WO2006136892A3/de
Priority to US12/003,272 priority Critical patent/US20080200652A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Neuartige Fusionsproteine enthalten Antikörperbinderegionen und bestimmte andere Regionen und können Komplexe mit Antikörpern bilden. Diese können somit modifiziert und in ihrer Wirkung verstärkt sowie räumlich angeordnet werden.
PCT/IB2006/001490 2005-06-20 2006-06-07 Neuartige cherlasky - fusionsproteine enthalten antikorperbindeproteine oder ihre regionen WO2006136892A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/003,272 US20080200652A1 (en) 2005-06-20 2007-12-21 Novel Cherkasky fusion proteins containing antibody binding proteins or the regions thereof

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE200510028619 DE102005028619A1 (de) 2005-06-20 2005-06-20 Neuartige Cherkasky-Fusionsproteine enthaltend Antikörperbindeproteine oder ihre Regionen
DE102005028619.4 2005-06-20
DE200510028545 DE102005028545A1 (de) 2005-06-21 2005-06-21 Neuartige Cherkasky - Fusionsproteine enthaltend Antikörperbindeproteine oder ihre Regionen
DE102005028545.7 2005-06-21

Publications (2)

Publication Number Publication Date
WO2006136892A2 WO2006136892A2 (de) 2006-12-28
WO2006136892A3 true WO2006136892A3 (de) 2007-08-23

Family

ID=37570806

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2006/001490 WO2006136892A2 (de) 2005-06-20 2006-06-07 Neuartige cherlasky - fusionsproteine enthalten antikorperbindeproteine oder ihre regionen

Country Status (2)

Country Link
US (1) US20080200652A1 (de)
WO (1) WO2006136892A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2447277A1 (de) 2010-10-28 2012-05-02 Laboratorios Del. Dr. Esteve, S.A. Impfstoffzusammensetzungen auf Basis von modifizierten gp41-Immunogenen

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004109A1 (fr) * 1995-07-21 1997-02-06 Universite Pierre Et Marie Curie (Paris Vi) PROTEINES HETERO-MULTIMERIQUES RECOMBINANTES DU TYPE α - β C4BP
WO2005040382A2 (de) * 2003-10-28 2005-05-06 Alexander Cherkasky Cherkasky - fusionsproteine enthaltend antikorperbinde-, antigenbinde - mikrotubulibinde und immunantwortauslosende

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5763733A (en) * 1994-10-13 1998-06-09 Enzon, Inc. Antigen-binding fusion proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997004109A1 (fr) * 1995-07-21 1997-02-06 Universite Pierre Et Marie Curie (Paris Vi) PROTEINES HETERO-MULTIMERIQUES RECOMBINANTES DU TYPE α - β C4BP
WO2005040382A2 (de) * 2003-10-28 2005-05-06 Alexander Cherkasky Cherkasky - fusionsproteine enthaltend antikorperbinde-, antigenbinde - mikrotubulibinde und immunantwortauslosende

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
BEGENT ET AL: "Novel antibody-based fusion proteins in cancer treatment", EUROPEAN JOURNAL OF CANCER, PERGAMON PRESS, OXFORD, GB, vol. 33, June 1997 (1997-06-01), pages S39, XP005064565, ISSN: 0959-8049 *
HEUSER C ET AL: "Anti-CD30-IL-12 antibody-cytokine fusion protein that induces IFN-gamma secretion of T cells and NK cell-mediated lysis of Hodgkin's lymphoma-derived tumor cells", INTERNATIONAL JOURNAL OF CANCER, NEW YORK, NY, US, vol. 106, no. 4, 10 September 2003 (2003-09-10), pages 545 - 552, XP002405178, ISSN: 0020-7136 *
JOOSTEN VIVI ET AL: "The production of antibody fragments and antibody fusion proteins by yeasts and filamentous fungi", MICROBIAL CELL FACTORIES, BIOMED CENTRAL, LONDON, NL, vol. 2, no. 1, 30 January 2003 (2003-01-30), pages 1, XP021007176, ISSN: 1475-2859 *
LODE H N ET AL: "Synergy between an antiangiogenic integrin alphav antagonist and an antibody-cytokine fusion protein eradicates spontaneous tumor metastases", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, NATIONAL ACADEMY OF SCIENCE, WASHINGTON, DC, US, vol. 96, no. 4, 16 February 1999 (1999-02-16), pages 1591 - 1596, XP002134006, ISSN: 0027-8424 *
ROHRBACH P ET AL: "THERAPEUTIC ANTIBODIES AND ANTIBODY FUSION PROTEINS", BIOTECHNOLOGY AND GENETIC ENGINEERING REVIEWS, INTERCEPT LTD., ANDOVER, GB, vol. 20, 2003, pages 137 - 163, XP009071969, ISSN: 0264-8725 *
SCOTT C ET AL: "Targeting of NPC1 to late endosomes involves multiple signals, including one residing within the putative sterol-sensing domain", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOCHEMICAL BIOLOGISTS, BIRMINGHAM,, US, vol. 279, no. 46, 12 November 2004 (2004-11-12), pages 48214 - 48223, XP002371639, ISSN: 0021-9258 *
STEIDLER L ET AL: "PAP PILI AS A VECTOR SYSTEM FOR SURFACE EXPOSITION OF AN IMMUNOGLOBULIN G-BINDING DOMAIN OF PROTEIN A OF STAPHYLOCOCCUS AUREUS IN ESCHERICHIA COLI", JOURNAL OF BACTERIOLOGY, WASHINGTON, DC, US, vol. 175, no. 23, 1 December 1993 (1993-12-01), pages 7639 - 7643, XP000612669, ISSN: 0021-9193 *
UGEN K E ET AL: "New recombinant multimer of two fusion proteins, each including part of C4 binding protein", VACCINE, BUTTERWORTH SCIENTIFIC. GUILDFORD, GB, vol. 15, no. 8, June 1997 (1997-06-01), pages 935, XP004075692, ISSN: 0264-410X *

Also Published As

Publication number Publication date
WO2006136892A2 (de) 2006-12-28
US20080200652A1 (en) 2008-08-21

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