WO2006132950A3 - Therapeutic polymers and methods of use - Google Patents
Therapeutic polymers and methods of use Download PDFInfo
- Publication number
- WO2006132950A3 WO2006132950A3 PCT/US2006/021395 US2006021395W WO2006132950A3 WO 2006132950 A3 WO2006132950 A3 WO 2006132950A3 US 2006021395 W US2006021395 W US 2006021395W WO 2006132950 A3 WO2006132950 A3 WO 2006132950A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- therapeutic
- poly
- polymer
- polymer compositions
- ester
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/0008—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition
- A61K48/0025—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid
- A61K48/0041—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'non-active' part of the composition delivered, e.g. wherein such 'non-active' part is not delivered simultaneously with the 'active' part of the composition wherein the non-active part clearly interacts with the delivered nucleic acid the non-active part being polymeric
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/74—Synthetic polymeric materials
- A61K31/785—Polymers containing nitrogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/593—Polyesters, e.g. PLGA or polylactide-co-glycolide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/595—Polyamides, e.g. nylon
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G71/00—Macromolecular compounds obtained by reactions forming a ureide or urethane link, otherwise, than from isocyanate radicals in the main chain of the macromolecule
- C08G71/04—Polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L77/00—Compositions of polyamides obtained by reactions forming a carboxylic amide link in the main chain; Compositions of derivatives of such polymers
- C08L77/12—Polyester-amides
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002610745A CA2610745A1 (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
AU2006255262A AU2006255262A1 (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
JP2008514885A JP2008542393A (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
EP06760640A EP1906976A4 (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68757005P | 2005-06-03 | 2005-06-03 | |
US60/687,570 | 2005-06-03 | ||
US75917906P | 2006-01-13 | 2006-01-13 | |
US60/759,179 | 2006-01-13 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006132950A2 WO2006132950A2 (en) | 2006-12-14 |
WO2006132950A3 true WO2006132950A3 (en) | 2007-06-14 |
Family
ID=37498935
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/021395 WO2006132950A2 (en) | 2005-06-03 | 2006-06-02 | Therapeutic polymers and methods of use |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1906976A4 (en) |
JP (1) | JP2008542393A (en) |
AU (1) | AU2006255262A1 (en) |
CA (1) | CA2610745A1 (en) |
WO (1) | WO2006132950A2 (en) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9102830B2 (en) | 2005-09-22 | 2015-08-11 | Medivas, Llc | Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use |
US9517203B2 (en) | 2000-08-30 | 2016-12-13 | Mediv As, Llc | Polymer particle delivery compositions and methods of use |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7273469B1 (en) | 2003-12-31 | 2007-09-25 | Advanced Cardiovascular Systems, Inc. | Modified needle catheter for directional orientation delivery |
JP2009530484A (en) * | 2006-03-24 | 2009-08-27 | メディバス エルエルシー | Biodegradable poly (ester-amide) containing alkylene-dicarboxylate and method of use |
WO2007133616A2 (en) * | 2006-05-09 | 2007-11-22 | Medivas, Llc | Biodegradable water soluble polymers |
US20080200377A1 (en) * | 2007-02-16 | 2008-08-21 | Trollsas Mikael O | Polymer particles |
EP2227223A4 (en) * | 2007-12-06 | 2013-11-27 | Medivas Llc | Oligo-ethylene glycol-based polymer compositions and methods of use |
EP2723800B1 (en) | 2011-06-23 | 2015-10-07 | DSM IP Assets B.V. | Micro- or nanoparticles comprising a biodegradable polyesteramide copolymer for use in the delivery of bioactive agents |
US9873765B2 (en) | 2011-06-23 | 2018-01-23 | Dsm Ip Assets, B.V. | Biodegradable polyesteramide copolymers for drug delivery |
US10434071B2 (en) | 2014-12-18 | 2019-10-08 | Dsm Ip Assets, B.V. | Drug delivery system for delivery of acid sensitivity drugs |
CA2988679A1 (en) | 2015-06-23 | 2016-12-29 | Phagelux (Canada), Inc. | Composition comprising amino acid polymers and a bioactive agent and method of preparing thereof |
CN110804175B (en) * | 2019-11-08 | 2021-05-14 | 中国科学院理化技术研究所 | Antibacterial polyamino acid derivative or copolymer with alternating structure and preparation method thereof |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503538B1 (en) * | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
US20040098118A1 (en) * | 2002-09-26 | 2004-05-20 | Endovascular Devices, Inc. | Apparatus and method for delivery of mitomycin through an eluting biocompatible implantable medical device |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001051027A2 (en) * | 2000-01-11 | 2001-07-19 | Intralytix, Inc. | Polymer blends as biodegradable matrices for preparing biocomposites |
US6703040B2 (en) * | 2000-01-11 | 2004-03-09 | Intralytix, Inc. | Polymer blends as biodegradable matrices for preparing biocomposites |
CA2771263A1 (en) * | 2000-07-27 | 2002-02-07 | Rutgers, The State University | Therapeutic polyesters and polyamides |
US8765164B2 (en) * | 2005-10-21 | 2014-07-01 | Kenneth W. Carpenter | Poly(ester urea) polymers and methods of use |
-
2006
- 2006-06-02 JP JP2008514885A patent/JP2008542393A/en active Pending
- 2006-06-02 CA CA002610745A patent/CA2610745A1/en not_active Abandoned
- 2006-06-02 EP EP06760640A patent/EP1906976A4/en not_active Withdrawn
- 2006-06-02 WO PCT/US2006/021395 patent/WO2006132950A2/en active Application Filing
- 2006-06-02 AU AU2006255262A patent/AU2006255262A1/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6503538B1 (en) * | 2000-08-30 | 2003-01-07 | Cornell Research Foundation, Inc. | Elastomeric functional biodegradable copolyester amides and copolyester urethanes |
US20040098118A1 (en) * | 2002-09-26 | 2004-05-20 | Endovascular Devices, Inc. | Apparatus and method for delivery of mitomycin through an eluting biocompatible implantable medical device |
Non-Patent Citations (1)
Title |
---|
See also references of EP1906976A4 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9517203B2 (en) | 2000-08-30 | 2016-12-13 | Mediv As, Llc | Polymer particle delivery compositions and methods of use |
US9102830B2 (en) | 2005-09-22 | 2015-08-11 | Medivas, Llc | Bis-(α-amino)-diol-diester-containing poly (ester amide) and poly (ester urethane) compositions and methods of use |
Also Published As
Publication number | Publication date |
---|---|
CA2610745A1 (en) | 2006-12-14 |
JP2008542393A (en) | 2008-11-27 |
WO2006132950A2 (en) | 2006-12-14 |
AU2006255262A1 (en) | 2006-12-14 |
EP1906976A4 (en) | 2011-11-09 |
EP1906976A2 (en) | 2008-04-09 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO2006132950A3 (en) | Therapeutic polymers and methods of use | |
WO2007050415A3 (en) | Poly(ester urea) polymers and methods of use | |
WO2007130477A3 (en) | Delivery of ophthalmologic agents to the exterior or interior of the eye | |
Talebian et al. | Self‐healing hydrogels: the next paradigm shift in tissue engineering? | |
WO2007112046A3 (en) | Alkylene-dicarboxylate-containing biodegradable poly(ester amides) and methods of use | |
WO2007133616A3 (en) | Biodegradable water soluble polymers | |
WO2008021548A3 (en) | Epoxy-containing poly(ester amides) and methods of use | |
WO2008048298A3 (en) | Polymer particles for delivery of macromolecules and methods of use | |
Schutgens et al. | Biomaterials for intervertebral disc regeneration: past performance and possible future strategies. | |
PL2244752T3 (en) | Low viscosity liquid polymeric delivery system | |
WO2007035938A3 (en) | BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE | |
WO2007069068A3 (en) | Cell penetrating peptide conjugates for delivering nucleic acids into cells | |
WO2006097355A8 (en) | Biodegradable aliphatic-aromatic copolyester | |
WO2006108009A3 (en) | Controlled degradation materials for therapeutic agent delivery | |
JP2012514121A5 (en) | ||
MX347056B (en) | Pharmaceutical compositions. | |
WO2008094834A3 (en) | Multi-functional drug carriers | |
MX2010001219A (en) | Tunably crosslinked hyaluronic acid compositions. | |
WO2010005723A3 (en) | Drug loaded polymeric nanoparticles and methods of making and using same | |
EP1932863A3 (en) | Soft thermoplastic polyurethane elastomers and processes for their preparation and use | |
WO2001051027A3 (en) | Polymer blends as biodegradable matrices for preparing biocomposites | |
WO2011112482A3 (en) | Polymeric drug delivery conjugates and methods of making and using thereof | |
WO2006022754A3 (en) | Radiopaque polymeric stents | |
GB0620685D0 (en) | Bioresorbable polymers | |
Shariatzadeh et al. | Injectable and reversible preformed cryogels based on chemically crosslinked gelatin methacrylate (GelMA) and physically crosslinked hyaluronic acid (HA) for soft tissue engineering |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2008514885 Country of ref document: JP Kind code of ref document: A |
|
ENP | Entry into the national phase |
Ref document number: 2610745 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 12007502735 Country of ref document: PH |
|
NENP | Non-entry into the national phase |
Ref country code: DE |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006255262 Country of ref document: AU |
|
WWE | Wipo information: entry into national phase |
Ref document number: 2006760640 Country of ref document: EP |
|
ENP | Entry into the national phase |
Ref document number: 2006255262 Country of ref document: AU Date of ref document: 20060602 Kind code of ref document: A |