WO2006125050A3 - Biobarcode assays for ultra high sensitive detection - Google Patents
Biobarcode assays for ultra high sensitive detection Download PDFInfo
- Publication number
- WO2006125050A3 WO2006125050A3 PCT/US2006/019170 US2006019170W WO2006125050A3 WO 2006125050 A3 WO2006125050 A3 WO 2006125050A3 US 2006019170 W US2006019170 W US 2006019170W WO 2006125050 A3 WO2006125050 A3 WO 2006125050A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- biobarcode
- assays
- ultra high
- sensitive detection
- high sensitive
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2458/00—Labels used in chemical analysis of biological material
- G01N2458/10—Oligonucleotides as tagging agents for labelling antibodies
Abstract
The invention provides an extremely sensitive, reliable, and adaptable detection method of chemical detection through signal amplification from a reporter reagent capable of selectively binding to the target chemical of interest. The invention utilizes a detection reagent containing a streptavidin-biotin complex or a particle that has been derivatized to include on its surface selective binding compounds that specifically bind to the target chemical species and a large number of copies of a pre-selected reporter moiety.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US68174005P | 2005-05-17 | 2005-05-17 | |
US60/681,740 | 2005-05-17 | ||
US68216005P | 2005-05-18 | 2005-05-18 | |
US60/682,160 | 2005-05-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2006125050A2 WO2006125050A2 (en) | 2006-11-23 |
WO2006125050A3 true WO2006125050A3 (en) | 2007-02-08 |
Family
ID=37075627
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2006/019170 WO2006125050A2 (en) | 2005-05-17 | 2006-05-17 | Biobarcode assays for ultra high sensitive detection |
Country Status (1)
Country | Link |
---|---|
WO (1) | WO2006125050A2 (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008140620A2 (en) * | 2006-12-21 | 2008-11-20 | Nanosphere, Inc. | Ultra sensitive biomolecule detection using double stranded dna co-loaded gold nanoparticles and co-immobilized capture molecules |
KR20100042082A (en) | 2008-10-15 | 2010-04-23 | 삼성전자주식회사 | Solid support with enhanced density of a signal material, kit containing the same and method for detecting target material using the same |
WO2012016936A1 (en) | 2010-07-31 | 2012-02-09 | Aj Innuscreen Gmbh | Detection of specific nucleic acid sequences by means of fluorescence quenching |
DE102010033107A1 (en) | 2010-08-02 | 2012-02-02 | Aj Innuscreen Gmbh | Detection of specific nucleic acid sequences by fluorescence quenching |
CN111693691B (en) * | 2019-03-14 | 2023-09-05 | 天津华科泰生物技术有限公司 | Polymer label based on porphyrin structure |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050037397A1 (en) * | 2001-03-28 | 2005-02-17 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
WO2005113817A2 (en) * | 2004-05-03 | 2005-12-01 | Nanosphere, Inc. | Aptamer-nanoparticle conjugates and method of use for target analyte detection |
-
2006
- 2006-05-17 WO PCT/US2006/019170 patent/WO2006125050A2/en active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050037397A1 (en) * | 2001-03-28 | 2005-02-17 | Nanosphere, Inc. | Bio-barcode based detection of target analytes |
WO2005113817A2 (en) * | 2004-05-03 | 2005-12-01 | Nanosphere, Inc. | Aptamer-nanoparticle conjugates and method of use for target analyte detection |
Non-Patent Citations (2)
Title |
---|
NAM JWA-MIN ET AL: "Bio-bar-code-based DNA detection with PCR-like sensitivity.", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY. 19 MAY 2004, vol. 126, no. 19, 19 May 2004 (2004-05-19), pages 5932 - 5933, XP002403224, ISSN: 0002-7863 * |
NAM JWA-MIN ET AL: "Nanoparticle-based bio-bar codes for the ultrasensitive detection of proteins.", SCIENCE. 26 SEP 2003, vol. 301, no. 5641, 26 September 2003 (2003-09-26), pages 1884 - 1886, XP002403223, ISSN: 1095-9203 * |
Also Published As
Publication number | Publication date |
---|---|
WO2006125050A2 (en) | 2006-11-23 |
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