WO2006102370A3 - Functional brain mri mapping as a marker in cns diseases and disorders - Google Patents

Functional brain mri mapping as a marker in cns diseases and disorders Download PDF

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Publication number
WO2006102370A3
WO2006102370A3 PCT/US2006/010324 US2006010324W WO2006102370A3 WO 2006102370 A3 WO2006102370 A3 WO 2006102370A3 US 2006010324 W US2006010324 W US 2006010324W WO 2006102370 A3 WO2006102370 A3 WO 2006102370A3
Authority
WO
WIPO (PCT)
Prior art keywords
disorders
marker
cns diseases
brain mri
functional brain
Prior art date
Application number
PCT/US2006/010324
Other languages
French (fr)
Other versions
WO2006102370A2 (en
Inventor
James Paskavitz
Original Assignee
Univ Massachusetts
James Paskavitz
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Massachusetts, James Paskavitz filed Critical Univ Massachusetts
Publication of WO2006102370A2 publication Critical patent/WO2006102370A2/en
Publication of WO2006102370A3 publication Critical patent/WO2006102370A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A61B5/165—Evaluating the state of mind, e.g. depression, anxiety
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/16—Devices for psychotechnics; Testing reaction times ; Devices for evaluating the psychological state
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4058—Detecting, measuring or recording for evaluating the nervous system for evaluating the central nervous system
    • A61B5/4064—Evaluating the brain
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/40—Detecting, measuring or recording for evaluating the nervous system
    • A61B5/4076—Diagnosing or monitoring particular conditions of the nervous system
    • G—PHYSICS
    • G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
    • G16H—HEALTHCARE INFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR THE HANDLING OR PROCESSING OF MEDICAL OR HEALTHCARE DATA
    • G16H50/00—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics
    • G16H50/20—ICT specially adapted for medical diagnosis, medical simulation or medical data mining; ICT specially adapted for detecting, monitoring or modelling epidemics or pandemics for computer-aided diagnosis, e.g. based on medical expert systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physiology (AREA)
  • Child & Adolescent Psychology (AREA)
  • Developmental Disabilities (AREA)
  • Educational Technology (AREA)
  • Neurosurgery (AREA)
  • Social Psychology (AREA)
  • Data Mining & Analysis (AREA)
  • Databases & Information Systems (AREA)
  • Epidemiology (AREA)
  • Primary Health Care (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)

Abstract

The invention relates in some aspects to methods of using functional connectivity brain mapping to assess predictive markers of selecting therapeutic agents, therapies, and/or treatment regimens based on predictive markers of CNS diseases that are determined using functional connectivity brain mapping. The methods of the invention are also useful for predicting whether a subject will or will not respond to a particular therapeutic agent or therapy.
PCT/US2006/010324 2005-03-22 2006-03-22 Functional brain mri mapping as a marker in cns diseases and disorders WO2006102370A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US66404705P 2005-03-22 2005-03-22
US60/664,047 2005-03-22

Publications (2)

Publication Number Publication Date
WO2006102370A2 WO2006102370A2 (en) 2006-09-28
WO2006102370A3 true WO2006102370A3 (en) 2008-10-23

Family

ID=37024549

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/010324 WO2006102370A2 (en) 2005-03-22 2006-03-22 Functional brain mri mapping as a marker in cns diseases and disorders

Country Status (1)

Country Link
WO (1) WO2006102370A2 (en)

Families Citing this family (26)

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US6684105B2 (en) 2001-08-31 2004-01-27 Biocontrol Medical, Ltd. Treatment of disorders by unidirectional nerve stimulation
US7778711B2 (en) 2001-08-31 2010-08-17 Bio Control Medical (B.C.M.) Ltd. Reduction of heart rate variability by parasympathetic stimulation
US8571653B2 (en) 2001-08-31 2013-10-29 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation techniques
US7885709B2 (en) 2001-08-31 2011-02-08 Bio Control Medical (B.C.M.) Ltd. Nerve stimulation for treating disorders
US7974693B2 (en) 2001-08-31 2011-07-05 Bio Control Medical (B.C.M.) Ltd. Techniques for applying, configuring, and coordinating nerve fiber stimulation
US7904176B2 (en) 2006-09-07 2011-03-08 Bio Control Medical (B.C.M.) Ltd. Techniques for reducing pain associated with nerve stimulation
US8036745B2 (en) 2004-06-10 2011-10-11 Bio Control Medical (B.C.M.) Ltd. Parasympathetic pacing therapy during and following a medical procedure, clinical trauma or pathology
US8204591B2 (en) 2002-05-23 2012-06-19 Bio Control Medical (B.C.M.) Ltd. Techniques for prevention of atrial fibrillation
US8320647B2 (en) 2007-11-20 2012-11-27 Olea Medical Method and system for processing multiple series of biological images obtained from a patient
JP5614599B2 (en) * 2010-12-06 2014-10-29 国立大学法人 岡山大学 Method and apparatus for confirming presence or absence of onset of dementia
CN102138782A (en) * 2011-03-10 2011-08-03 电子科技大学 Brain functional effective connection analyzing method
US9370660B2 (en) 2013-03-29 2016-06-21 Rainbow Medical Ltd. Independently-controlled bidirectional nerve stimulation
CA2969425A1 (en) * 2014-12-01 2016-06-09 The Feinstein Institute For Medical Research Use of striatal connectivity patterns for evaluating antipsychotic agents
US10105540B2 (en) 2015-11-09 2018-10-23 Bluewind Medical Ltd. Optimization of application of current
CN105249964B (en) * 2015-11-10 2017-12-22 东南大学 Appraisal procedure is rebuild based on magneticencephalogram and the multi-modal brain function of diffusion tensor
US10390766B2 (en) 2017-01-16 2019-08-27 General Electric Company System and method for predicting an excitation pattern of a deep brain stimulation
US10624588B2 (en) 2017-01-16 2020-04-21 General Electric Company System and method for predicting an excitation pattern of a deep brain stimulation
JP6722845B2 (en) * 2017-10-03 2020-07-15 株式会社国際電気通信基礎技術研究所 Discriminating apparatus, depressive symptom discriminating method, depressive symptom level determining method, depressive patient stratification method, depressive symptom therapeutic effect determining method, and brain activity training apparatus
CN107967686B (en) * 2017-12-27 2021-07-06 电子科技大学 Epilepsy recognition device combining dynamic brain network and long-time and short-time memory network
EP3776591A1 (en) * 2018-03-28 2021-02-17 Icahn School of Medicine at Mount Sinai Systems and methods for processing connectivity values between sub-processing regions
CN109330596B (en) * 2018-11-15 2022-04-12 郑州轻工业学院 Brain function connection dynamic variability measurement method based on time window analysis
CN110246566A (en) * 2019-04-24 2019-09-17 中南大学湘雅二医院 Method, system and storage medium are determined based on the conduct disorder of convolutional neural networks
US11733332B2 (en) 2019-12-09 2023-08-22 Nous Imaging, Inc. Systems and method of precision functional mapping-guided interventional planning
CN111755120B (en) * 2020-06-29 2023-07-21 西南民族大学 Cognitive disorder prediction method based on edge intelligence and multimode perception
CN112686098B (en) * 2020-12-15 2023-05-26 中国人民解放军战略支援部队信息工程大学 Shape-Resnet-based method and system for processing signals of middle and high-grade vision areas of brain
CN114533066B (en) * 2022-04-28 2022-08-19 之江实验室 Social anxiety assessment method and system based on composite expression processing brain network

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6400978B1 (en) * 1999-10-29 2002-06-04 The Mclean Hospital Corporation Method and apparatus for detecting mental disorders
US6434419B1 (en) * 2000-06-26 2002-08-13 Sam Technology, Inc. Neurocognitive ability EEG measurement method and system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6400978B1 (en) * 1999-10-29 2002-06-04 The Mclean Hospital Corporation Method and apparatus for detecting mental disorders
US6434419B1 (en) * 2000-06-26 2002-08-13 Sam Technology, Inc. Neurocognitive ability EEG measurement method and system

Also Published As

Publication number Publication date
WO2006102370A2 (en) 2006-09-28

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