WO2006097205A3 - Verfahren zur extrakorporalen analyse von haarfollikelzellen - Google Patents

Verfahren zur extrakorporalen analyse von haarfollikelzellen Download PDF

Info

Publication number
WO2006097205A3
WO2006097205A3 PCT/EP2006/001946 EP2006001946W WO2006097205A3 WO 2006097205 A3 WO2006097205 A3 WO 2006097205A3 EP 2006001946 W EP2006001946 W EP 2006001946W WO 2006097205 A3 WO2006097205 A3 WO 2006097205A3
Authority
WO
WIPO (PCT)
Prior art keywords
hair follicle
hair
homeostasis
promoting
maintaining
Prior art date
Application number
PCT/EP2006/001946
Other languages
English (en)
French (fr)
Other versions
WO2006097205A2 (de
Inventor
Melanie Giesen
Dirk Petersohn
Kordula Schlotmann
Zur Wiesche Erik Schulze
Elisabeth Poppe
Original Assignee
Henkel Kgaa
Melanie Giesen
Dirk Petersohn
Kordula Schlotmann
Zur Wiesche Erik Schulze
Elisabeth Poppe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Henkel Kgaa, Melanie Giesen, Dirk Petersohn, Kordula Schlotmann, Zur Wiesche Erik Schulze, Elisabeth Poppe filed Critical Henkel Kgaa
Priority to EP06723191A priority Critical patent/EP1859272A2/de
Publication of WO2006097205A2 publication Critical patent/WO2006097205A2/de
Publication of WO2006097205A3 publication Critical patent/WO2006097205A3/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/12—Preparations containing hair conditioners
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5038—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects involving detection of metabolites per se

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Public Health (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

Die vorliegende Erfindung betrifft ein Verfahren zur extrakorporalen Analyse von Haarfollikelzellen, ein Verfahren zur extrakorporalen Bestimmung der ATP- Syntheserate in Haarfollikelzellen, ferner ein Testverfahren zum Nachweis der Wirksamkeit von kosmetischen oder pharmazeutischen Wirkstoffen zur Aufrechterhaltung oder Förderung der Homeostase des Haarfollikels bzw. zur Behandlung pathologischer Zustände des Haarfollikels sowie ein Screening- Verfahren zur Identifikation von kosmetischen oder pharmazeutischen Wirkstoffen zur Aufrechterhaltung oder Förderung der Homeostase des Haarfollikels bzw. zur Behandlung pathologischer Zustände des Haarfollikels und ein Verfahren zur Herstellung einer kosmetischen oder pharmazeutischen Zubereitung zur Aufrechterhaltung oder Förderung der Homeostase des Haarfollikels bzw. zur Behandlung pathologischer Zustände des Haarfollikels. Weiterhin betrifft die Erfindung ein Haarbehandlungsmittel, enthaltend mindestens eine Verbindung, die ausgewählt ist unter L-Camitin oder L-Carnitinderivaten, sowie deren Verwendungen, insbesondere zur Aktivierung des Haarstoffwechsels.
PCT/EP2006/001946 2005-03-14 2006-03-03 Verfahren zur extrakorporalen analyse von haarfollikelzellen WO2006097205A2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP06723191A EP1859272A2 (de) 2005-03-14 2006-03-03 Verfahren zur extrakorporalen analyse von haarfollikelzellen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE200510011957 DE102005011957A1 (de) 2005-03-14 2005-03-14 Neues Haarbehandlungsmittel, enthaltend L-Carnitin oder L-Carnitinderivate
DE102005011957.3 2005-03-14

Publications (2)

Publication Number Publication Date
WO2006097205A2 WO2006097205A2 (de) 2006-09-21
WO2006097205A3 true WO2006097205A3 (de) 2008-03-13

Family

ID=36992082

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2006/001946 WO2006097205A2 (de) 2005-03-14 2006-03-03 Verfahren zur extrakorporalen analyse von haarfollikelzellen

Country Status (3)

Country Link
EP (1) EP1859272A2 (de)
DE (1) DE102005011957A1 (de)
WO (1) WO2006097205A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005062356A1 (de) * 2005-12-23 2007-06-28 Henkel Kgaa Verringerung der Haaralterung
DE102006042243A1 (de) * 2006-09-06 2008-03-27 Henkel Kgaa Mittel, enthaltend Biochinone und Betaine
KR101483805B1 (ko) * 2007-01-30 2015-01-16 파마시클릭스, 인코포레이티드 히스톤 데아세틸라제 억제제에 대한 암 내성을 확인하는 방법
FR2918267B1 (fr) * 2007-07-03 2010-09-17 Oreal Utilisation de l-carnitine et/ou de ses derives pour attenuer, diminuer ou stopper la pousse des cheveux et des poils
DE102009044974A1 (de) * 2009-07-23 2011-01-27 Henkel Ag & Co. Kgaa Verwendung von Dihydroquercetin und mindestens einer Aminosäure zur positiven Beeinflussung des natürlichen Pigmentierungsprozesses
DE102009044975A1 (de) * 2009-07-23 2011-01-27 Henkel Ag & Co. Kgaa Verwendung von Carnitin und Dihydroquercetin zur positiven Beeinflussung des natürlichen Pigmentierungsprozesses
DE102009044964A1 (de) * 2009-09-24 2011-03-31 Henkel Ag & Co. Kgaa Verwendung einer Kombination aus Carnitin und/oder eines Carnitin-Derivats mit Purin und/oder einem Purin-Derivat zur Beeinflussung des natürlichen Pigmentierungsprozesses
DE102009043486A1 (de) 2009-09-30 2010-07-01 Henkel Ag & Co. Kgaa Verwendung von Wirkstoffen, erhältlich aus Pflanzen, zur Verhinderung und/oder Verminderung der Auswirkungen von psychoemotionalem Stress auf das Haar
DE102009043485A1 (de) 2009-09-30 2011-03-31 Henkel Ag & Co. Kgaa Verfahren zur Bestimmung von Stress
US20110281256A1 (en) 2010-05-17 2011-11-17 Michael Glenn Davis Systems and Methods of Detecting and Demonstrating Hair Damage Via Evaluation of Protein Fragments
DE102011079661A1 (de) * 2011-07-22 2013-01-24 Henkel Ag & Co. Kgaa Verfahren zur individualisierten Haarbehandlung
FR3090347B1 (fr) * 2018-12-20 2020-12-18 Oreal Procédé de traitement des fibres kératiniques mettant en œuvre une composition comprenant un sel de carnitine ou de dérivé de carnitine comprenant un anion d’acide dicarboxylique aliphatique

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08127520A (ja) * 1994-10-28 1996-05-21 Kyotaro Hasunuma 養毛化粧料
DE19539859A1 (de) * 1995-10-26 1997-04-30 Eugen Konrad Haar und Hautbehandlungsmittel
DE19618670A1 (de) * 1996-05-09 1997-11-13 Wella Ag Haar- und Hautbehandlungsmittel
DE19618671A1 (de) * 1996-05-09 1997-11-13 Wella Ag Haar- und Hautbehandlungsmittel
WO2002074265A1 (de) * 2001-03-19 2002-09-26 Hans Schwarzkopf Gmbh & Co. Kg Haarbehandlungsmittel mit betainen
WO2002094872A1 (en) * 2001-05-24 2002-11-28 Human Dna Technology Inc Therapeutic uses of keratinocyte growth factor-2
WO2004028495A1 (de) * 2002-09-19 2004-04-08 Henkel Kommanditgesellschaft Auf Aktien Haarbehandlungsmittel enthaltend eine wirkstoffkombination mit liposomen
WO2004059002A2 (de) * 2002-12-20 2004-07-15 Henkel Kommanditgesellschaft Auf Aktien Verfahren zur bestimmung der homeostase behaarter haut

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
US5885766A (en) * 1995-02-17 1999-03-23 Societe L'oreal S.A. Method of screening of substances for their effect on the expression of mediators of inflammation in a hair follicle
DE19631685A1 (de) * 1996-08-06 1998-02-12 Wella Ag Hydrolytisch spaltbare Wirkstoffderivate, diese enthaltene Haarbehandlungsmittel und Verfahren zum Behandeln von Haaren
WO1998034610A1 (en) * 1997-02-10 1998-08-13 Groton Robert B Composition for improving hair regrowth and method of use
DE10036797A1 (de) * 2000-07-28 2002-02-07 Beiersdorf Ag Verwendung von Kombinationen mit einem Gehalt an Carnitinen
DE10036798A1 (de) * 2000-07-28 2002-02-07 Beiersdorf Ag Mittel zur Behandlung der Haare und der Kopfhaut
CA2678135C (en) * 2003-02-28 2012-12-04 Elc Management Llc Method for increasing hair growth using a creatine compound

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08127520A (ja) * 1994-10-28 1996-05-21 Kyotaro Hasunuma 養毛化粧料
DE19539859A1 (de) * 1995-10-26 1997-04-30 Eugen Konrad Haar und Hautbehandlungsmittel
DE19618670A1 (de) * 1996-05-09 1997-11-13 Wella Ag Haar- und Hautbehandlungsmittel
DE19618671A1 (de) * 1996-05-09 1997-11-13 Wella Ag Haar- und Hautbehandlungsmittel
WO2002074265A1 (de) * 2001-03-19 2002-09-26 Hans Schwarzkopf Gmbh & Co. Kg Haarbehandlungsmittel mit betainen
WO2002094872A1 (en) * 2001-05-24 2002-11-28 Human Dna Technology Inc Therapeutic uses of keratinocyte growth factor-2
WO2004028495A1 (de) * 2002-09-19 2004-04-08 Henkel Kommanditgesellschaft Auf Aktien Haarbehandlungsmittel enthaltend eine wirkstoffkombination mit liposomen
WO2004059002A2 (de) * 2002-12-20 2004-07-15 Henkel Kommanditgesellschaft Auf Aktien Verfahren zur bestimmung der homeostase behaarter haut

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
GREEN M R ET AL: "RAPID ISOLATION IN LARGE NUMBERS OF INTACT VIABLE INDIVIDUAL HAIR FOLLICLES FROM SKIN BIOCHEMICAL AND ULTRASTRUCTURAL CHARACTERIZATION", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 87, no. 6, 1986, pages 768 - 770, XP002444989, ISSN: 0022-202X *
PHILPOTT M P ET AL: "Human hair growth in vitro", JOURNAL OF CELL SCIENCE, CAMBRIDGE UNIVERSITY PRESS, LONDON, GB, vol. 97, no. 3, 1990, pages 463 - 471, XP003000714, ISSN: 0021-9533 *
PHILPOTT M P ET AL: "METABOLIC STUDIES ON ISOLATED HAIR FOLLICLES: HAIR FOLLICLES ENGAGE IN AEROBIC GLYCOLYSIS AND DO NOT DEMONSTRATE THE GLUCOSE FATTY ACID CYCLE", JOURNAL OF INVESTIGATIVE DERMATOLOGY, NEW YORK, NY, US, vol. 96, no. 6, June 1991 (1991-06-01), pages 875 - 879, XP008063099, ISSN: 0022-202X *
See also references of EP1859272A2 *
WILLIAMS REBECCA ET AL: "Metabolism of freshly isolated human hair follicles capable of hair elongation: A glutaminolytic, aerobic glycolytic tissue", JOURNAL OF INVESTIGATIVE DERMATOLOGY, vol. 100, no. 6, 1993, pages 834 - 840, XP002444992, ISSN: 0022-202X *

Also Published As

Publication number Publication date
DE102005011957A1 (de) 2006-12-07
WO2006097205A2 (de) 2006-09-21
EP1859272A2 (de) 2007-11-28

Similar Documents

Publication Publication Date Title
WO2006097205A3 (de) Verfahren zur extrakorporalen analyse von haarfollikelzellen
Dobrota et al. Carnosine protects the brain of rats and Mongolian gerbils against ischemic injury: after-stroke-effect
RU2008103480A (ru) Средство, содержащее l-карнитин или производные l-карнитина и, по меньшей мере, одно определенное другое вещество
WO2007064872A3 (en) Urea compounds useful in the treatment of cancer
NO20081211L (no) Xantinderivater som selektive HM74A agonister
ATE470443T1 (de) Indol-1-yl-essigsäurederivate
NO20071549L (no) Nye benzofuserte heteroalrylsulfamidderivater, anvendelige som anti-krampemidler
WO2007127505A3 (en) Use of sulfonamide derivatives in the treatment of disorders of the metabolism and the nervous system
Zeng et al. Mechanism of fisetin suppressing superoxide anion and xanthine oxidase activity
WO2009032773A3 (en) Compositions and methods for treating demodex infestations
IL184898A0 (en) Pyrrolopyrimidine derivatives and pharmaceutical compositions containing the same
EP3311818A3 (de) Hemmer der bruton-tyrosinkinase zur behandlung solider tumore
EP1599213A4 (de) Zellmembran-translokation von regulierten snare- inhibitoren, zusammensetzungen dafür und verfahren zur behandlung von erkrankungen
IL176007A0 (en) Antibodies specific to c35 and pharmaceutical compositions containing the same
WO2006119510A3 (en) Isoforms of receptor for advanced glycation end products (rage) and methods of identifying and using same
MY162640A (en) Thioninium compounds and their use
WO2006096444A3 (en) Chemical compounds
EA201001283A1 (ru) Комбинация витамина d и 25-гидроксивитамина d3
de Oliveira Azevedo et al. Antinociceptive and anti-inflammatory effects of myricetin 3-O-β-galactoside isolated from Davilla elliptica: involvement of the nitrergic system
WO2002053774A3 (de) Verfahren zur bestimmung der homeostase der haut
WO2017038951A1 (ja) 黄ぐすみ低減用皮膚外用剤
PL1868631T3 (pl) Zastosowanie związków indukujących syntezę białek SIRT przy lub dla otrzymywania kompozycji kosmetycznej lub farmaceutycznej
WO2007077318A3 (fr) Utilisation d'un extrait peptidique de riz en tant qu'agent actif inducteur de la synthese des proteines sirt dans les cellules de la peau
HK1093016A1 (en) Use of alpha-ketoglutaric acid for the treatment of malnutrition or high plasma glucose condition
WO2005052140A3 (en) Multipotent postnatal stem cells from human periodontal ligament and uses thereof

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 2006723191

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

NENP Non-entry into the national phase

Ref country code: RU

WWW Wipo information: withdrawn in national office

Country of ref document: RU

WWP Wipo information: published in national office

Ref document number: 2006723191

Country of ref document: EP