WO2006069741A3 - Gelartiges material zur füllung von knochen- und/oder knorpeldefekten - Google Patents

Gelartiges material zur füllung von knochen- und/oder knorpeldefekten Download PDF

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Publication number
WO2006069741A3
WO2006069741A3 PCT/EP2005/013925 EP2005013925W WO2006069741A3 WO 2006069741 A3 WO2006069741 A3 WO 2006069741A3 EP 2005013925 W EP2005013925 W EP 2005013925W WO 2006069741 A3 WO2006069741 A3 WO 2006069741A3
Authority
WO
WIPO (PCT)
Prior art keywords
gel
type material
cartilage defects
filling bone
collagen
Prior art date
Application number
PCT/EP2005/013925
Other languages
English (en)
French (fr)
Other versions
WO2006069741A2 (de
Inventor
Marco Springer
Arne Briest
Original Assignee
Ossacur Ag
Marco Springer
Arne Briest
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ossacur Ag, Marco Springer, Arne Briest filed Critical Ossacur Ag
Priority to US11/722,528 priority Critical patent/US20090017093A1/en
Priority to EP05850340A priority patent/EP1835945A2/de
Publication of WO2006069741A2 publication Critical patent/WO2006069741A2/de
Publication of WO2006069741A3 publication Critical patent/WO2006069741A3/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/52—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14—Macromolecular materials
    • A61L27/22—Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24—Collagen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412—Tissue-regenerating or healing or proliferative agents
    • A61L2300/414—Growth factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/426—Immunomodulating agents, i.e. cytokines, interleukins, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/80—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special chemical form
    • A61L2300/802—Additives, excipients, e.g. cyclodextrins, fatty acids, surfactants

Abstract

Es wird ein gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten bereitgestellt, welches mindestens eine gelbildende Komponente und Kollagen in mindestens einem flüssigen Dispersionsmittel umfaßt, wobei das Kollagen einen Wirkstoffkomplex aufweist. Bevorzugt besitzt das Material osteokonduktive und -induktive Eigenschaften.
PCT/EP2005/013925 2004-12-23 2005-12-22 Gelartiges material zur füllung von knochen- und/oder knorpeldefekten WO2006069741A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US11/722,528 US20090017093A1 (en) 2004-12-23 2005-12-22 Gelatinous material for filling bone and/or cartilage defects
EP05850340A EP1835945A2 (de) 2004-12-23 2005-12-22 Gelartiges material zur f]llung von knochen- und/oder knorpeldefekten

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
DE102004063210.3 2004-12-23
DE102004063210 2004-12-23
DE102005018283.6 2005-04-13
DE102005018283 2005-04-13
DE102005034420.8 2005-07-13
DE102005034420A DE102005034420A1 (de) 2004-12-23 2005-07-13 Gelartiges Material zur Füllung von Knochen- und/oder Knorpeldefekten

Publications (2)

Publication Number Publication Date
WO2006069741A2 WO2006069741A2 (de) 2006-07-06
WO2006069741A3 true WO2006069741A3 (de) 2006-10-12

Family

ID=36590671

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2005/013925 WO2006069741A2 (de) 2004-12-23 2005-12-22 Gelartiges material zur füllung von knochen- und/oder knorpeldefekten

Country Status (4)

Country Link
US (1) US20090017093A1 (de)
EP (1) EP1835945A2 (de)
DE (1) DE102005034420A1 (de)
WO (1) WO2006069741A2 (de)

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US20040081704A1 (en) * 1998-02-13 2004-04-29 Centerpulse Biologics Inc. Implantable putty material
US20020114795A1 (en) * 2000-12-22 2002-08-22 Thorne Kevin J. Composition and process for bone growth and repair
US7166133B2 (en) 2002-06-13 2007-01-23 Kensey Nash Corporation Devices and methods for treating defects in the tissue of a living being
ITTO20040918A1 (it) * 2004-12-29 2005-03-29 Luigi Ambrosio Idrogel polimerici superassorbenti biodegradabili e procedimento per la loro preparazione
DE102005030614B4 (de) 2005-06-30 2014-05-08 Biotissue Ag Zellfreies Transplantat, dessen Verwendung, Verfahren zu dessen Herstellung, dabei hergestellte Matrix mit Gel und Verfahren zur Herstellung dieser Matrix mit Gel
DE102006047346A1 (de) 2006-10-06 2008-04-10 Transtissue Technologies Gmbh Matrix-Gel-Transplantat ohne Zellen
US7718616B2 (en) * 2006-12-21 2010-05-18 Zimmer Orthobiologics, Inc. Bone growth particles and osteoinductive composition thereof
EP1964583A1 (de) 2007-02-09 2008-09-03 Royal College of Surgeons in Ireland Verfahren zur Herstellung eines Kollagen/Hydroxyapatitverbundgerüsts
DE102009042493B4 (de) 2009-09-14 2016-07-21 Celgen3D Ag Granulatmischung, umfassend zwei verschiedene Granulate, zur künstlichen Kallusdistraktion
CN103313733A (zh) 2010-11-15 2013-09-18 捷迈整形外科生物材料有限公司 骨空隙填充剂
US8524662B2 (en) 2010-12-28 2013-09-03 Depuy Mitek, Llc Compositions and methods for treating joints
US8398611B2 (en) 2010-12-28 2013-03-19 Depuy Mitek, Inc. Compositions and methods for treating joints
US8455436B2 (en) 2010-12-28 2013-06-04 Depuy Mitek, Llc Compositions and methods for treating joints
DE102011011092A1 (de) * 2011-02-09 2012-08-23 Amedrix Gmbh Gelierendes Kollagen und Mittel zu dessen Bereitstellung
US8623839B2 (en) 2011-06-30 2014-01-07 Depuy Mitek, Llc Compositions and methods for stabilized polysaccharide formulations
WO2015162561A1 (en) * 2014-04-21 2015-10-29 Ineb - Instituto Nacional De Engenharia Biomédica Composition for local and controlled release of drugs and methods thereof
US9238090B1 (en) 2014-12-24 2016-01-19 Fettech, Llc Tissue-based compositions
US9682099B2 (en) 2015-01-20 2017-06-20 DePuy Synthes Products, Inc. Compositions and methods for treating joints

Citations (8)

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WO1993016657A1 (en) * 1992-02-28 1993-09-02 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
WO1993020857A1 (de) * 1992-04-11 1993-10-28 Karlheinz Schmidt Verfahren zur herstellung von wirkstoffkomplexen
US20020031551A1 (en) * 1996-04-16 2002-03-14 Peterson Dale R. Bioerodable polymeric adhesives for tissue repair
US20020076429A1 (en) * 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
US20020183855A1 (en) * 1995-10-16 2002-12-05 Yamamoto Ronald K. Tissue repair matrix
US20020192263A1 (en) * 1998-02-27 2002-12-19 Merboth Barbara L. Allograft bone composition having a gelatin binder
US20020197242A1 (en) * 1998-02-27 2002-12-26 Gertzman Arthur A. Composition for filling bone defects
WO2004060425A2 (en) * 2002-12-27 2004-07-22 Angiotech International Ag Compositions and methods of using collagen and mmpi

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DE69132973T2 (de) * 1991-12-30 2002-11-21 Norian Corp Mineralisiertes kollagen
US5532217A (en) * 1992-04-24 1996-07-02 Silver; Frederick H. Process for the mineralization of collagen fibers, product produced thereby and use thereof to repair bone
CN1264390A (zh) * 1997-05-28 2000-08-23 清水庆彦 胶原凝胶
DE19962090B4 (de) * 1998-12-22 2014-07-17 Karl Weis Verfahren zur Herstellung von Formkörpern
ATE243049T1 (de) * 1999-12-09 2003-07-15 Biosyntech Canada Inc Mineral-polymer hybrid-zusammensetzung
US20040078090A1 (en) * 2002-10-18 2004-04-22 Francois Binette Biocompatible scaffolds with tissue fragments
US7316822B2 (en) * 2003-11-26 2008-01-08 Ethicon, Inc. Conformable tissue repair implant capable of injection delivery
DE102004036882A1 (de) * 2004-07-22 2006-02-16 Ossacur Ag Bioresorbierbares Material zur Füllung von Knochendefekten
DE102004036881A1 (de) * 2004-07-22 2006-02-16 Ossacur Ag Bioresorbierbares Material zur Füllung von Knochendefekten

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993016657A1 (en) * 1992-02-28 1993-09-02 Collagen Corporation Injectable ceramic compositions and methods for their preparation and use
WO1993020857A1 (de) * 1992-04-11 1993-10-28 Karlheinz Schmidt Verfahren zur herstellung von wirkstoffkomplexen
US20020183855A1 (en) * 1995-10-16 2002-12-05 Yamamoto Ronald K. Tissue repair matrix
US20020031551A1 (en) * 1996-04-16 2002-03-14 Peterson Dale R. Bioerodable polymeric adhesives for tissue repair
US20020076429A1 (en) * 1998-01-28 2002-06-20 John F. Wironen Bone paste subjected to irradiative and thermal treatment
US20020192263A1 (en) * 1998-02-27 2002-12-19 Merboth Barbara L. Allograft bone composition having a gelatin binder
US20020197242A1 (en) * 1998-02-27 2002-12-26 Gertzman Arthur A. Composition for filling bone defects
WO2004060425A2 (en) * 2002-12-27 2004-07-22 Angiotech International Ag Compositions and methods of using collagen and mmpi

Also Published As

Publication number Publication date
WO2006069741A2 (de) 2006-07-06
EP1835945A2 (de) 2007-09-26
US20090017093A1 (en) 2009-01-15
DE102005034420A1 (de) 2006-07-06

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