WO2006060140A3 - Monoclonal anti-idiotypic antibody as a probe to define the viral receptor and as a vaccine candidate for porcine reproductive and respiratory syndrome virus - Google Patents

Monoclonal anti-idiotypic antibody as a probe to define the viral receptor and as a vaccine candidate for porcine reproductive and respiratory syndrome virus Download PDF

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Publication number
WO2006060140A3
WO2006060140A3 PCT/US2005/040971 US2005040971W WO2006060140A3 WO 2006060140 A3 WO2006060140 A3 WO 2006060140A3 US 2005040971 W US2005040971 W US 2005040971W WO 2006060140 A3 WO2006060140 A3 WO 2006060140A3
Authority
WO
WIPO (PCT)
Prior art keywords
probe
define
monoclonal anti
respiratory syndrome
syndrome virus
Prior art date
Application number
PCT/US2005/040971
Other languages
French (fr)
Other versions
WO2006060140A2 (en
Inventor
En-Min Zhou
Original Assignee
Univ Iowa State Res Found Inc
En-Min Zhou
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Iowa State Res Found Inc, En-Min Zhou filed Critical Univ Iowa State Res Found Inc
Publication of WO2006060140A2 publication Critical patent/WO2006060140A2/en
Publication of WO2006060140A3 publication Critical patent/WO2006060140A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4216—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-viral Ig
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

This disclosure outlines a particular monoclonal anti-idiotype antibody, designated Mab2-3H. This antibody has been established as being capable of eliciting an anti-GP5 response, and to induce neutralization antibodies to PRRS infection in porcine cells.
PCT/US2005/040971 2004-11-12 2005-11-11 Monoclonal anti-idiotypic antibody as a probe to define the viral receptor and as a vaccine candidate for porcine reproductive and respiratory syndrome virus WO2006060140A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US62706404P 2004-11-12 2004-11-12
US60/627,064 2004-11-12

Publications (2)

Publication Number Publication Date
WO2006060140A2 WO2006060140A2 (en) 2006-06-08
WO2006060140A3 true WO2006060140A3 (en) 2006-10-12

Family

ID=36565504

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/040971 WO2006060140A2 (en) 2004-11-12 2005-11-11 Monoclonal anti-idiotypic antibody as a probe to define the viral receptor and as a vaccine candidate for porcine reproductive and respiratory syndrome virus

Country Status (1)

Country Link
WO (1) WO2006060140A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111450248B (en) * 2020-04-29 2023-02-28 西北农林科技大学 Antibody medicine for preventing and treating PRRSV infection
CN114316038B (en) * 2022-01-15 2023-06-27 杭州恒奥科技有限公司 Rapid detection test strip for porcine reproductive and respiratory syndrome virus, and preparation method and application thereof
CN117025545B (en) * 2023-08-10 2024-04-09 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） Hybridoma cell strain secreting highly pathogenic porcine reproductive and respiratory syndrome virus specific monoclonal antibody and application thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040014028A1 (en) * 2002-07-19 2004-01-22 Wolf Biotech Method for determination of protective epitopes for vaccination, diagnosis and vaccine quality control

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040014028A1 (en) * 2002-07-19 2004-01-22 Wolf Biotech Method for determination of protective epitopes for vaccination, diagnosis and vaccine quality control

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HORTER ET AL.: "Characterization of the carrier state in porcine reproductive and respiratory syndrome virus infection", VETERINARY MICROBIOLOGY, vol. 86, 2002, pages 213 - 228 *

Also Published As

Publication number Publication date
WO2006060140A2 (en) 2006-06-08

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