WO2006055726A3 - Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations - Google Patents

Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations Download PDF

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Publication number
WO2006055726A3
WO2006055726A3 PCT/US2005/041708 US2005041708W WO2006055726A3 WO 2006055726 A3 WO2006055726 A3 WO 2006055726A3 US 2005041708 W US2005041708 W US 2005041708W WO 2006055726 A3 WO2006055726 A3 WO 2006055726A3
Authority
WO
WIPO (PCT)
Prior art keywords
healing
composition
ulcerations
slow
facilitating
Prior art date
Application number
PCT/US2005/041708
Other languages
French (fr)
Other versions
WO2006055726A2 (en
Inventor
Lindsey Berkson
Kenneth G Burton
Original Assignee
Lindsey Berkson
Kenneth G Burton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US10/992,636 external-priority patent/US20060105027A1/en
Priority claimed from US10/992,623 external-priority patent/US7731993B2/en
Application filed by Lindsey Berkson, Kenneth G Burton filed Critical Lindsey Berkson
Priority to EP05826664A priority Critical patent/EP1827466A4/en
Priority to JP2007543244A priority patent/JP2008520694A/en
Priority to AU2005307736A priority patent/AU2005307736A1/en
Priority to BRPI0517731-6A priority patent/BRPI0517731A/en
Priority to CA002588119A priority patent/CA2588119A1/en
Publication of WO2006055726A2 publication Critical patent/WO2006055726A2/en
Publication of WO2006055726A3 publication Critical patent/WO2006055726A3/en
Priority to IL183117A priority patent/IL183117A0/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Botany (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

A composition for treatment of non-healing and slow-healing wounds and ulcerations, and for treating and preventing peripheral neuropathy. The composition is primarily characterized by a combination of nitroglycerin, arginine and curcumin. Preferred embodiments comprise emollient cream, mineral oil, and zinc oxide.
PCT/US2005/041708 2004-11-17 2005-11-17 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations WO2006055726A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP05826664A EP1827466A4 (en) 2004-11-17 2005-11-17 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations
JP2007543244A JP2008520694A (en) 2004-11-17 2005-11-17 Compositions and methods for promoting healing of non-healing and delayed healing wounds and ulcers
AU2005307736A AU2005307736A1 (en) 2004-11-17 2005-11-17 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations
BRPI0517731-6A BRPI0517731A (en) 2004-11-17 2005-11-17 composition and method for facilitating healing of non-healing slow healing wounds and ulcerations
CA002588119A CA2588119A1 (en) 2004-11-17 2005-11-17 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations
IL183117A IL183117A0 (en) 2004-11-17 2007-05-10 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US10/992,636 US20060105027A1 (en) 2004-11-17 2004-11-17 Method for treating skin ulcers
US10/992,636 2004-11-17
US10/992,623 2004-11-17
US10/992,623 US7731993B2 (en) 2004-11-17 2004-11-17 Composition for treating a dermal anomaly

Publications (2)

Publication Number Publication Date
WO2006055726A2 WO2006055726A2 (en) 2006-05-26
WO2006055726A3 true WO2006055726A3 (en) 2007-03-22

Family

ID=36407755

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2005/041708 WO2006055726A2 (en) 2004-11-17 2005-11-17 Composition and method for facilitating the healing of non-healing and slow-healing wounds and ulcerations

Country Status (7)

Country Link
EP (1) EP1827466A4 (en)
JP (1) JP2008520694A (en)
AU (1) AU2005307736A1 (en)
BR (1) BRPI0517731A (en)
CA (1) CA2588119A1 (en)
IL (1) IL183117A0 (en)
WO (1) WO2006055726A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5401504A (en) * 1993-12-28 1995-03-28 University Of Mississippi Medical Center Use of turmeric in wound healing
US5672336A (en) * 1989-09-11 1997-09-30 Sharma; Vinay K. Process of preparing microparticulate collagen, collagen-based products thereby and method of applying same
US5693676A (en) * 1994-05-27 1997-12-02 Neptune Pharmaceutical Corporation Nitric oxide donor composition and method for treatment of anal disorders
US20030104033A1 (en) * 2001-07-13 2003-06-05 Lai Chon-Si Enteral formulations

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0665647B2 (en) * 1985-06-12 1994-08-24 株式会社三和化学研究所 Transdermal treatment agent
US5698589A (en) * 1993-06-01 1997-12-16 International Medical Innovations, Inc. Water-based topical cream containing nitroglycerin and method of preparation and use thereof
US5925376C1 (en) * 1994-01-10 2001-03-20 Madalene C Y Heng Method for treating psoriasis using selected phosphorylase kinase inhibitor and additional compounds
US5543430A (en) * 1994-10-05 1996-08-06 Kaesemeyer; W. H. Method and formulation of stimulating nitric oxide synthesis
US5891472A (en) * 1996-11-19 1999-04-06 Meri Charmyne Russell Treatment of equine laminitis
JP3667027B2 (en) * 1997-03-06 2005-07-06 株式会社ノエビア Topical skin preparation
CN1298309A (en) * 1998-02-27 2001-06-06 同步神经元有限责任公司 Method for treating painful conditions of the anal region and compositions therefor
US6627632B2 (en) * 1998-12-14 2003-09-30 Cellegy Pharmaceuticals, Inc. Compositions and methods for the treatment of anorectal disorders
US20030091601A1 (en) * 2001-11-13 2003-05-15 Abat Inc. Use of topical arginine to enhance wound healing

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5672336A (en) * 1989-09-11 1997-09-30 Sharma; Vinay K. Process of preparing microparticulate collagen, collagen-based products thereby and method of applying same
US5401504A (en) * 1993-12-28 1995-03-28 University Of Mississippi Medical Center Use of turmeric in wound healing
US5401504B1 (en) * 1993-12-28 1998-04-21 Univ Mississippi Medical Cente Use of tumeric in wound healing
US5693676A (en) * 1994-05-27 1997-12-02 Neptune Pharmaceutical Corporation Nitric oxide donor composition and method for treatment of anal disorders
US20030104033A1 (en) * 2001-07-13 2003-06-05 Lai Chon-Si Enteral formulations

Also Published As

Publication number Publication date
EP1827466A4 (en) 2009-11-11
AU2005307736A1 (en) 2006-05-26
CA2588119A1 (en) 2006-05-26
BRPI0517731A (en) 2008-10-21
WO2006055726A2 (en) 2006-05-26
JP2008520694A (en) 2008-06-19
IL183117A0 (en) 2007-10-31
EP1827466A2 (en) 2007-09-05

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